Ivermectin Tested against 28 types of Cancer: Most Sensitive vs Least Sensitive

A research group from Mexico investigated Ivermectin in Cancer. This is the first study that has tested as many as 28 Cancer types with Ivermectin. 


Paper: 2020 (Juarez et al) - Antitumor effects of ivermectin at clinically feasible concentrations support its clinical development as a repositioned cancer drug. 

Ivermectin was tested at 2mg/kg/day which translates to roughly 5uM in vitro concentration.

The most sensitive cancer cell lines were: 1. Ovarian 2. Breast 3. Glioblastoma 4. Lung Cancer 5. Colon Cancer 6. Uterine SCC 7. hepatocellular 8. breast TNBC 9. Pancreatic 10. Endometrial.

Least sensitive were: 1. osteosarcoma 2. gastric 3. melanoma 

Although lymphoma and leukemia cell lines appear to be more resistant to Ivermectin, Ivermectin has a significant impact on those cells' ability to form colonies. So yes, Ivermectin is useful against BOTH lymphomas and leukemias. 

Ivermectin also goes after CANCER STEM CELLS, which tend to be resistant to chemotherapy:
 
“Ivermectin has a preferential depletion effect on the cancer stem-like cell population…” 

“We observed that among all the evaluated cell lines, a decrease in cell viability and clonogenicity is more evident in the cancer stem-like cells than in their parental population.” 

Ivermectin was also found to be synergistic with docetaxel, cyclophosphamide and tamoxifen.

KEY findings of this study: At a human dose of 2mg/kg, Ivermectin can achieve anti-cancer effects such as cell cycle arrest (inhibit proliferation), preferrential inhibition of cancer stem-like cells, synergize with several chemotherapy drugs and inhibit tumor growth in a breast cancer mouse model. 

Ivermectin and Cancer: Evidence in Human Subjects

Read more than 700 case reports and some of the stage 4 cancer case reports in "Ivermectin and Fenbendazole Cancer Success Stories: Case Reports Compilation". Some achieved NED - the remarkable category of “No Evidence of Disease” where their scans showed no more evidence of cancer. When this occurs in metastatic cancer, it is tantamount to a miracle for those patients and their families. However, it's vital to consult with qualified medical professionals regarding any treatment decisions.

While conventional medical professionals often regard case reports as anecdotal or lower-quality evidence, they generally prioritize large, double-blinded, randomized placebo-controlled trials (RCTs) as the gold standard. We acknowledge that RCTs provide stronger evidence. 

Still, the potential benefits of Ivermectin, coupled with its comparatively low risk profile and cost, warrant serious consideration and further exploration. Typically, when one adds ivermectin to standard cancer treatment, they might improve their outcome, meaning that the tumor shrinks faster or their cancer biomarkers, such as PSA, CA 125, or CEA drop.

When this occurs in Stage 1, 2, or 3 cancers, it is sometimes difficult to tell whether it was the standard treatment, that is the surgery, chemotherapy, radiation or immunotherapy that produced the benefit. However, when the cancer has progressed to Stage 4, and particularly when it involves one of the often-incurable cancers such as the types in the below table under the “Palliation Only (Metastatic)” category where standard chemotherapy is largely ineffective, it becomes obvious that the repurposed drug made the difference.

New & Improved Joe Tippens Protocol

In 2016, Joe Tippens was diagnosed with non-small-cell lung cancer with extensive metastatic disease. At the advice of a veterinarian friend, he took Fenbendazole together with nanocurcumin, and three months after starting these drugs his PET scan was completely clear.

Below is a modified version of the Joe Tippens protocol, a synergistic combination of fenbendazole, ivermectin and nutraceuticals, updated based on the ivermectin and mebendazole based protocol published in the Journal of Orthomolecular Medicine (2024):
  • Ivermectin (24 mg, 6 days a week) or in the case of severe aggressive cancers up to 1mg/kg/day.
  • Mebendazole (Dose of 200 - 400 mg/day) or Fenbendazole, commonly taken at 300 mg for six days a week, with doses increasing to up to 1 gram in cases of aggressive cancers.
  • Vitamin D (62.5 mcg [2500 IU] seven days a week).
  • Bio-Available Curcumin (600 mg per day, 7 days a week). 
  • Enhanced absorption Berberine (500 mg per day) to starve your cancer of sugar.
  • Diet and Lifestyle: 
    • 2026 study (American Association for Cancer Research), linked Ultra-Processed Foods to Reduced Survival after Cancer. Sugar, starch, saturated fat packed into ultra-processed food not only associated with obesity, diabetes, and heart disease, it also worsens cancer prognosis.
    • Another 2026 study published in The BMJ examined how everyday exposure to food preservatives influences cancer risk. The findings were clear — people who consumed more preservatives had higher rates of overall cancer and breast cancer. The findings support recommendations for consumers to favour freshly made, minimally processed foods.
    • Another 2026 findings published in Nature Communications, insulin resistance has been linked to a 25% higher risk of 12 different types of cancer. Insulin resistance is often caused by obesity and its associated chronic inflammation. Both diabetes and obesity are associated with a higher risk of cancer. 
    • Adopt a whole-food diet and avoid ultra-processed foods, as recommended by the BMJ 2024 guidelines. 
    • Eliminate sugar consumption as supported by the BMJ 2023 umbrella review, which recommends reducing free and added sugars to below 25 g/day and limiting sugar-sweetened beverages to less than one serving per week to reduce adverse health effects. 
    • Additionally, prioritise adequate sleep and effective stress management to support overall health.
*Notes:
  • Please note that this protocol now includes the vital Vitamin D addition, with the one day off for the fenbendazole administration. This protocol represents the most comprehensive and cutting edge repurposed drug and vitamin treatment approach to date.
  • Vitamin E: Removed from the protocol (Joe Tippens, July 22, 2020) due to interactions (e.g., with blood thinners).


RELATED: 



Ivermectin and mebendazole, both approved for human use, are now available in the U.S.

Researched and approved by Dr. Peter McCullough.
  • Prescribed by licensed medical professionals
  • Compounded and dispensed by a licensed US-based pharmacy
  • Approved for human use
Where to buy Ivermectin and Mebendazole Formula: Available on The Wellness Company's website. Here is the link: Ivermectin and Mebendazole.

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