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Dementia risk was linked with blood levels of certain antioxidants, an observational study showed. Higher serum levels of lutein+zeaxanthin and beta-cryptoxanthin -- two types of carotenoids -- were tied to a lower risk of incident dementia, reported May Beydoun, PhD, MPH, of the NIH National Institute on Aging in Baltimore, Maryland, and colleagues, in  Neurology . Findings were attenuated in adjusted analyses, suggesting socioeconomic status, lifestyle, and diet quality may mediate the associations. When oxidative stress occurs at an abnormally high level, consuming antioxidants may help protect cells of the body, including brain cells, from damage, Beydoun noted. "Carotenoids, which are the pigments found in orange and yellow plants, are converted by the body into vitamin A. We found that the most important carotenoids in potentially protecting the brain may be lutein+zeaxanthin and beta-cryptoxanthin," she told  MedPage Today . "Unlike other studies, we did not analy

Age-related macular degeneration (AMD), a leading cause of blindness in the United States, is said to be a disease associated with aging but Dr. Chris Knobbe believes it’s mostly related to diet. Nine years of extensive research and investigation has led Knobbe to conclude that AMD is driven by nutrient deficiencies and toxicity caused by processed foods. Knobbe, an ophthalmologist, is the founder and president of the Cure AMD Foundation, a nonprofit dedicated to the prevention of AMD. If Knobbe is correct, and his data and biochemical analysis suggests he is, it would line up with what we know about the most common chronic diseases today, including Type 2 diabetes, heart disease, and cancer. The root of the problem lies in mitochondrial dysfunction, which is caused by the excessive consumption of the so-called Standard American Diet, including toxic industrially processed seed oils (incorrectly called “vegetable oils”), refined flour, refined added sugars, and trans fats. Laying out h

Endocrine disrupting chemicals (EDCs) are similar in structure to natural hormones such as the female sex hormone estrogen, the male sex hormone androgen and thyroid hormones, which allow them to interfere with development, 1   reproduction, neurological functioning, metabolism, satiety and your immune system function, and much more. 2 For example, they may block certain hormonal signals, alter your hormone levels or change the way your natural hormones travel through your body. As noted in a World Health Organization report published in 2012, 3 , 4  the effects of EDCs on your hormonal systems “can lead to obesity, infertility or reduced fertility, learning and memory difficulties, Type 2 diabetes or cardiovascular disease, as well as a variety of other diseases." What’s more, since hormones operate at parts per million and parts per billion concentrations, the Endocrine Society warns there may be no safe level of exposure for many EDCs, 5

David Sinclair, Ph.D., A.O. is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School . Dr. David Sinclair’s main research interest is the epigenetics of aging, with a focus on epigenetic reprogramming of aging (e.g. via Yamanaka factors ), NAD+ metabolism and sirtuins, and NAD+ precursors like NR and NMN . You may have come across his published, New York Times best-selling book on aging, “ Lifespan: Why We Age – And Why We Don’t Have To ”, going deeper into those subjects. So what supplements does Professor David Sinclair take to live longer? Keep in mind that to date, Dr. David Sinclair has made a point to not promote or endorse any supplement products. We compiled this list from interviews and books in which Professor David Sinclair mentions supplements he takes. We don’t know if he still takes these supplements, or whether he takes additional supplements that are not included on this list. Fo