Repurposing Anthelmintics for Cancer Treatment: A Fenbendazole-Based Protocol with Ivermectin and Mebendazole (2025)
Introduction Cancer remains one of the most challenging diseases to treat, despite advances in targeted therapies, immunotherapy, and precision medicine. As patients seek alternative and complementary treatments, drug repurposing has gained significant attention. Among these repurposed drugs, fenbendazole (FBZ) —a broad-spectrum anthelmintic commonly used in veterinary medicine—has emerged as a potential anticancer agent. Initially anecdotal, reports of its effectiveness in various cancer types have sparked interest in its mechanisms and possible therapeutic role. Several patients, including Joe Tippens , have publicly shared their experiences of tumor regression and disease stabilization after integrating fenbendazole into their cancer treatment regimens. Encouraged by these cases, further investigations have explored its microtubule-disrupting, apoptosis-inducing, and glucose-metabolism-inhibiting properties, which resemble the mechanisms of e...