Fenbendazole and Ivermectin Testimonials in Multiple Sclerosis, Rheumatoid Arthritis and Osteoarthritis (2025)

Is there any research on the utility of the anti-parasitic Fenbendazole in Multiple Sclerosis? Yes, but it's very well hidden, and you've likely never heard of it. I'll be honest, I hadn't either. There is a 2010 paper by Australian Researchers led by A A Ramp: "Strain-related effects of fenbendazole treatment on murine experimental autoimmune encephalomyelitis".

Dr William Makis posted on X/Twitter:

What is murine experimental autoimmune encephalomyelitis? Animal model of Multiple Sclerosis! "FBZ is delivered orally by premixing into rodent chow at a rate of 150 mg/kg of diet. This assumes an average daily food intake of 8 mg/kg body weight, sufficient to ensure a therapeutic dose". Rodent chow. Sounds delicious. FENBENDAZOLE decreased # of sick mice from 99% to 38.6% in one MS disease model (NOD/LtJ) FENBENDAZOLE decreased # of sick mice from 99% to 62.5% in another MS disease model (C57BL/6J) These are absolutely wild results and completely unknown to the world. Have a look at the attached tables. For any Multiple Sclerosis patient, I would start a trial of Fenbendazole at either 444mg or 888mg daily depending on the weight. The adverse events at these doses are minimal vs the potential benefit!

Read More: Multiple Sclerosis series.

In another post (2025), Dr Makis shared:

"Ivermectin and Fenbendazole can bring significant relief in Rheumatoid Arthritis as well as Osteoarthritis! I have several testimonials already and more people willing to try every day."

Ivermectin and Fenbendazole Testimonial - 72 year old ER Physician with Osteoarthritis

Dr Makis shared on X (Twitter) in March 2025 in another post:

IVERMECTIN and FENBEDAZOLE Testimonial - 72 year old ER Physician with Osteoarthritis reports back after 3 weeks: Osteoarthritis...would you have thought of Ivermectin or Fenbendazole? I hadn't, to be honest... 72 year old ER Physician who took Ivermectin 12mg and Fenbendazole 222mg for 3 weeks: “Pain basically gone” “Morning stiffness greatly improved” “Real improvement immediately began with the addition of Fenbendazole” This one surprised me a bit. "So grateful for your post on X. I've been at my wits end to try to stop the osteoarthritis progression" There seems to be an anti-inflammatory effect to Fenbendazole I didn’t account for!