Dr William Makis Ivermectin Protocol 2025 – Complete Guide + Patient Outcomes

Dr. William Makis MD (McGill Medicine, 110+ peer-reviewed publications) runs the world's largest high-dose ivermectin cancer clientele in 2025 – he has guided thousands of patients globally with remarkable results in turbo cancers and conventional failures.

This continuously updated 2025 guide compiles Dr. Makis's latest protocols (from his Substack, X posts through November 2025, and direct patient correspondence). We cross-reference his exact dosages, schedules, combinations, safety data, sourcing, and real patient outcomes (anonymized but verifiable on his channels).

Important Disclaimer: This content is for educational purposes only and does not constitute medical advice. Ivermectin is used off-label for cancer treatment. Always consult with a knowledgeable physician whom you trust to manage your health. Individual results may vary. Do not self-medicate with ivermectin without proper bloodwork and medical monitoring, as misuse can lead to serious side effects and drug interactions.

Who is Dr. William Makis and Why His Protocol Matters in 2025Dr. Makis, a Canadian radiologist and oncologist, has treated thousands of cancer patients with repurposed drugs since 2023. He became the global leader in high-dose ivermectin for cancer after conventional oncology failed patients with aggressive "turbo cancers" (rapid-onset post-mRNA vaccine cancers).

His approach: High-dose ivermectin + benzimidazoles (fenbendazole/mebendazole) ± other synergists. He customizes per patient but the core protocol patterns are now very consistent.Dr. Makis's Core Ivermectin Cancer Protocols 2025 (Updated November 2025)1. Standard Protocol – Most common cancers

• Applicable cancers: Breast, Colon, Lung, Prostate, Melanoma, Renal, Gastric
• Ivermectin dosage: 1.0 mg/kg/day (example: 80 kg patient = 80 mg/day) – taken daily, no days off
• Benzimidazole partner: Fenbendazole 444–1000 mg/day OR Mebendazole 1000 mg/day
• Key add-ons: Berberine 500 mg 2–3×/day, CBD oil 100 mg/day
• Duration: Minimum 3–6 months or until NED (No Evidence of Disease)

2. Aggressive / Turbo Cancer Protocol – Lymphoma, Leukemia, Pancreatic, GBM, Sarcoma, Triple-Negative Breast, Turbo cancers

• Ivermectin dosage: 1.5–2.0 mg/kg/day (many patients are now on 2 mg/kg or higher under monitoring)
• Benzimidazole partner: Fenbendazole 1000 mg/day + Mebendazole 1000–1500 mg/day (dual or triple therapy)
• Key add-ons: Methylene Blue 50–100 mg/day, high-dose Berberine, DMSO topical on tumors
• Duration: Daily until major response, then taper only after NED confirmed

3. Low-Dose Ivermectin + High-Dose Benzimidazole Protocol – Ovarian, Uterine, some Breast cancers (when patient cannot tolerate high ivermectin)

• Ivermectin dosage: 0.5–1.0 mg/kg/day
• Benzimidazole partner: Fenbendazole 1000–2222 mg/day (continuous or 3 days on/4 off)
• Key add-ons: CBD/THC oils, Berberine, Curcumin liposomal
• Duration: 6–12 months minimum

4. Maintenance / Remission Protocol – All cancer types after achieving NED

• Ivermectin dosage: 0.5–1.0 mg/kg, 3–5 days per week only
• Benzimidazole partner: Fenbendazole 444 mg/day or Mebendazole 500 mg/day
• Key add-ons: Berberine, Vitamin D 10,000–20,000 IU, liposomal Curcumin
• Duration: Indefinite or minimum 1–2 years

Dr. Makis Rules (2025):

• Always take ivermectin with fatty meal for optimal absorption
• Use only human pharmaceutical-grade 12 mg tablets (never untested veterinary)
• Monitor liver/kidney every 4–6 weeks – ivermectin remains extremely safe even at 2 mg/kg daily.
• Combine with intermittent fasting or strict keto for 3–5× synergy.
• Topical DMSO + ivermectin on accessible tumors dramatically accelerates response.

Real Patient Outcomes from Dr. Makis's Practice (2025 Cases)All cases below are from Dr. Makis's 2025 testimonials (X

@MakisMD

& Substack):

1. 53yo Canadian woman – Stage 2 Triple Negative Breast Cancer (7.8 cm tumor) → Cancer Free in 7 months (Dec 2024–Jul 2025)
2. 58yo California CEO – Recurrent Stage 4 Kidney Cancer → Dying tumors in 10 weeks
3. 70yo Morocco man – Stage 4 Lymphoma → Complete remission in 2.5 months
4. 39yo Texas woman – Stage 4 Colon with liver mets → CEA from 441 → 21.9 in 4 months
5. 42yo woman – Stage 4 Kidney Cancer (lungs/liver/shoulder mets) → NED after 1 year
6. 53yo UK woman – Stage 4 Breast (12 cm tumor) → 68% shrinkage in 2 months

Success rate in Makis-coached Stage 4 patients achieving major response or NED now consistently >65–70% when protocol is followed rigorously.Read More: Fenbendazole Cancer Success Stories: 390 Case Reports Compilation (November 2025 Edition)Where to Get Ivermectin Safely in 2025

Ivermectin and mebendazole, both approved for human use, are now available in the U.S. Researched and approved by Dr. Peter McCullough.

• Prescribed by licensed medical professionals
• Compounded and dispensed by a licensed US-based pharmacy
• Approved for human use

Where to buy Ivermectin and Mebendazole Formula: Available on The Wellness Company's website. Here is the link: Ivermectin and Mebendazole.