The Medical Advisor

By Dr. Francis Yap · Aesthetics Advisor / One Day Media Network · Originally published June 2026 · Updated October 8, 2026 · About 14 min read Quick Answer “Ozempic face” is facial volume loss and skin laxity that can follow substantial weight loss on GLP-1 medicines. The best evidence links it to the amount of weight lost, not a proven direct drug effect. About 25–40% of weight lost in trial substudies is lean mass (not all of it muscle). Strength training, adequate protein, and a maintenance plan lower the risks; stopping treatment typically brings back roughly 0.8 kg a month. [1] [2] [3] [5] Key takeaways (October 2026) Facial change tracks weight lost. Imaging in 20 patients showed about 7% midfacial volume loss per 10 kg lost; the study had no control group. [5] Lean mass loss is real but often misread. Lean mass was roughly 25% (tirzepatide) to 38% (semaglutide) of weight lost in DXA substudies, and it includes water, organs, and bone, not only muscle. [1] [2] Muscl...

Since its approval for human dermatological use, ivermectin has transformed how we manage specific inflammatory and parasitic skin conditions—most notably rosacea and scabies. If you are struggling with persistent facial redness, bumps, or intense itching, understanding how ivermectin works can help you determine if it is the right addition to your skincare regimen. What is Ivermectin and How Does It Work for Skin? Ivermectin is a powerful anti-parasitic and anti-inflammatory medication available in both topical (cream) and oral (pill) forms. In dermatology, it works via a dual-action mechanism: it eliminates microscopic skin parasites while simultaneously calming the pathways that cause swelling, redness, and acne-like lesions. Topical vs. Oral Ivermectin: A Quick Reference Depending on your diagnosis, a dermatologist will prescribe either a localized cream or a systemic oral dose. Here is how they compare: Form Common Brand Names Primary Skin Co...

Demodex mites are microscopic, eight-legged arthropods that commonly live in human hair follicles and sebaceous glands. They are often called “face mites” because they are especially associated with facial skin, eyelashes and eyebrows. The surprising part is how difficult it is to answer a seemingly simple question: How many adults actually have Demodex mites? Some studies have reported extremely high prevalence, including one molecular study in which Demodex DNA was detected in 100% of adults over 18 in a small sample . But a much larger 2025 systematic review and meta-analysis estimated a global pooled prevalence of approximately 35% across the available studies. The key lesson: “100% of adults have Demodex” is too absolute as a general population statement. The available evidence suggests that Demodex is extremely common in adults, but the measured prevalence varies dramatically according to age, population, body site and—especia...