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McCullough Protocol Base Spike Detox: Nattokinase, Bromelain & Curcumin (2026)

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Quick Answer: What is the Base Spike Detox Protocol? The Base Spike Detox Protocol is an over-the-counter oral regimen developed by cardiologist Dr. Peter McCullough designed to assist the body in degrading and clearing persistent SARS-CoV-2 spike protein resulting from COVID-19 infection or vaccination. The core protocol consists of three natural compounds taken daily for a minimum of 3 to 12 months: Nattokinase: 2,000 FU (100 mg) twice daily on an empty stomach. Bromelain: 500 mg once daily on an empty stomach. Nano/Liposomal Curcumin: 500 mg twice daily with food. Medical Note: Due to significant fibrinolytic and antiplatelet properties, individuals taking prescription anticoagulants (blood thinners) or antiplatelet agents must consult a physician before starting. Key Takeaways Targeted Spike Degradation: Nattokinase directly degrades SARS-CoV-2 spike protein in cell models, while bromelain assists in secondary protein clearin...

Base Spike Detox Protocol: Nattokinase, Bromelain, and Curcumin for Clearance of Persistent SARS-CoV-2 Spike Protein (2026)

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Immune Systems Advisor Formerly The COVID Advisor — evidence-based analysis of long COVID, immune injury, and post-viral disease Review Article · Post-COVID & Post-Vaccine Syndrome A clinical review of the evidence base, dosing rationale, safety considerations, and monitoring strategy for the Base Spike Detox regimen in long COVID and post-vaccine injury syndromes — updated June 2026. Last Updated: June 2026 Authors: Editorial Team, Immune Systems Advisor Abstract Persistent SARS-CoV-2 spike protein — derived from infection, vaccination, or both — has been proposed as a pathophysiological driver of long COVID and post-vaccine inflammatory syndromes. Dr. Peter McCullough, a board-certified internist and cardiologist, has developed a three-agent over-the-counter regimen termed the "Base Spike Detox" that combines nattokinase (2,000 FU twice daily), ...

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