Fenbendazole vs Ivermectin for Cancer: What's the difference?

In recent years, unconventional drugs like Fenbendazole and Ivermectin have gained popularity as alternative forms of treatment for cancer. We’ve broken down the essential things you need to know about these medications for cancer in humans.

What Is Ivermectin?

Ivermectin is an anti-parasite drug used to treat various parasite infections in humans, but it can also be used to treat other health conditions like river blindness, onchocerciasis, intestinal strongyloidiasis, and onchocerciasis.

What Is Fenbendazole?

Fenbendazole is a benzimidazole that offers a wide spectrum anthelmintic effect. It is a dewormer medication used to treat parasites in dogs and cats. Some common names for Fenbendazole are Panacur® and Safe-Guard®.

Note: In everyday conversations within the fenbendazole communities, you might encounter Fenbendazole referred to as Phenbendazole, Panacur or SafeGuard. This interchangeability is representative of the common use of the trademarked name; it signifies a consensus within these circles that these terms denote the same medication. Fenbendazole is the active ingredient in all these products. Molecular formula for fenbendazole is C15H13N3O2S.

The Role of Ivermectin in Cancer Symptoms

Several clinical trials have been done to prove the effectiveness of Ivermectin against cancer cells with low enough dosages to be non-toxic to the normal cells. Research suggests that Ivermectin suppresses the growth and spread of cancer cells and promotes cancer cell death. Ivermectin proved successful against cancer cells when combined with chemotherapy or other targeted drugs and shows brilliant effectiveness against conventional chemotherapy drug-resistant cancer cells.

Ivermectin also shows efficacy for colorectal antitumor properties. Colorectal cancer still doesn’t have an effective treatment, but Ivermectin has been shown to possess anti-virus, anti-inflammatory, and antitumor properties. Another study shows that after treatment with Ivermectin for breast cancer, the proliferation of multiple breast cancer cell lines was significantly reduced.

The Role of Fenbendazole in Cancer Symptoms

Fenbendazole acts as a moderate microtubule destabilizing agent and possesses a potent antitumor effect. Fenbendazole causes cancer cells to erupt by modulating multiple cellular pathways. To prove the effectiveness of using fenbendazole for cancer, a study treated human non-small cell lung cancer with this dewormer. The cancer cells were analyzed, and researchers found that fenbendazole causes partial alteration of the microtubule network around the nucleus of the cell. There was also an increase in the WT p53 tumor suppressor genes, which enhanced cell death-inducing activity.

Cancer cells have been shown to use more glucose to fuel their energy requirements. Researchers tested the effectiveness of fenbendazole on glucose uptake in human cancer cells and found inhibition of glucose in the cell lines. Researchers also suggest that fenbendazole can be beneficial in evading the drug resistance encountered in cancer therapy.

Should You Use Ivermectin or Fenbendazole for Cancer?

Ivermectin Effectiveness

  • Ivermectin and breast cancer Ivermectin has been found to turn cold breast tumors hot. Cold tumors mean there are little to no infiltrating T-cells. However, Ivermectin treatment led to robust T-cell infiltration, which turned the tumors into hot ones. This suggests that Ivermectin could synergize with proteins like the PD-1, which help the immune system by acting as a brake on T-cells. This will increase immunity and help the body eradicate cancer.
  • Ivermectin and digestive system cancer Clinical studies show that dose-dependant Ivermectin inhibits the proliferation of glioblastoma cells in humans and induced apoptosis. Ivermectin has the potential to resist tumor angiogenesis and tumor metastasis.
  • Ivermectin and lung cancer Ivermectin significantly inhibits the production of lung cancer cells by inhibiting the YAP1 activity. Ivermectin can also reduce the metastasis of lung cancer cells by impeding EMT.
  • Ivermectin and melanoma Melanoma cells were treated with Ivermectin and showed the potential to effectively inhibit melanoma activity.
  • Ivermectin and ovarian cancer Ivermectin has the potential to block a cell cycle and induce cell apoptosis in ovarian cancer. The combination of Ivermectin and paclitaxel has a synergized effect on ovarian cancer. A combined treatment of these two almost completely inhibited tumor growth in vivo.
  • Ivermectin and colon cancer Ivermectin has been shown to have anti-virus, anti-inflammatory, and anti-tumor properties when it comes to colorectal cancer.

Fenbendazole Effectiveness

  • Fenbendazole and prostate cancer Fenbendazole has been shown to be cytotoxic against paclitaxel-resistant prostate cancer.
  • Fenbendazole and lung cancer Fenbendazole has been found to be effective against small cell lung cancer, and one of the success stories of this is Joe Tippens, who had small cell lung cancer that spread to his neck, right lung, stomach, liver, bladder, pancreas, and tail bone—and he was given three months to live. He managed to cure his cancer with a mix of fenbendazole, curcumin, CBD oil, and vitamin E, and has been cancer-free ever since.
  • Fenbendazole and lymphoma A recent study shows that a combination of fenbendazole and supplemented vitamins inhibited the growth of human lymphoma cells in mice.
Overall, when it comes to cancer in the body, fenbendazole has been shown to destroy the tubular structure of the cancer cells, reduce the ability of cancer cells to metabolize, and boost the body’s immune response to the cancer cells.

Ivermectin and Fenbendazole for Cancer

When taken together, ivermectin and fenbendazole deliver a one-two punch to cancer. When combined with other anti-cancer nutrients such as quercetin, vitamins C and D, and curcumin, the effects are even more pronounced.

Preclinical studies show that both ivermectin and fenbendazole exhibit cytotoxic effects against cancer cells. The two drugs also inhibit the growth and spread of cancerous tumors.

"The mechanisms underlying these effects appear to involve disruption of critical cellular processes, leading to cancer cell death," wrote Sid Belzberg in a paper cited by one of 2nd Smartest Guy in the World's readers.

Both ivermectin and fenbendazole are off-patent drugs, meaning their original intended use as licensed has expired and they have become generics. This allows for many different generic drug manufacturers, including a slew of them across India, to produce them cheaply and abundantly.

United States regulators make it hard to access them without a prescription – unless you purchase the versions available for pets – but they are out there. And when combined with other anti-cancer vitamins and minerals they show incredible promise in cancer prevention and mitigation.

You will be hard-pressed to find much helpful information about these two drugs in the mainstream, though. Because they are off-patent, ivermectin and fenbendazole bring in minimal profits, which means pharmaceutical companies are not interested in promoting them or touting their benefits.

Belzberg makes the case for ivermectin and fenbendazole to be compounded with other complementary substances to create a synergistic anti-cancer concoction that is safe and effective for widespread use.

"Despite these challenges, the repurposing of these compounds carries potential advantages that justify further exploration," Belzberg wrote. "Since the safety and pharmacokinetic profiles of these substances are well-known, their development as anticancer agents could be faster and less expensive than for new drugs."

"Furthermore, the successful repurposing of these compounds could provide a cost-effective way to expand anticancer treatments, possibly improving patient outcomes while reducing healthcare costs."

Another paper by Belzberg suggests that taking ivermectin with quercetin can synergistically fight prion diseases, also known as transmissible spongiform encephalopathies, or TSEs.

TSEs represent a group of fatal neurodegenerative diseases characterized by the misfolding of the prion protein, or PrP.

"The promise shown by ivermectin and quercetin in their potential anti-prion activities and their modulation of tauopathy offers an interesting avenue for further exploration," he wrote.

New & Improved Joe Tippens Protocol

  • Tocotrienol and Tocopherol forms (all 8) of Vitamin E (400-800mg per day, 7 days a week). A product called Gamma E by Life Extension or Perfect E are both great.
  • Bio-Available Curcumin (600mg per day, 2 pills per day 7 days a week). A product called Theracurmin HP by Integrative Therapeutics is bioavailable.
  • Vitamin D (62.5 mcg [2500 IU] seven days a week).
  • CBD oil (1-2 droppers full [equal to 167 to 334 mg per day] under the tongue, 7 days a week) CBD-X: The most potent full spectrum organic CBD oil, with 5,000 milligrams of activated cannabinoids and hemp compounds CBD, CBN & CBG per serving.
  • Fenbendazole (300 mg, 6 days a week) or in the case of severe turbo cancers up to 1 gram
  • Ivermectin (24 mg, 7 days a week) or in the case of severe turbo cancers up to 1mg/kg/day
  • Removing sugars and carbohydrates from one’s diet is crucial during this protocol.

In Summary: Which Product Is Better?

It is impossible to say which product is more effective as both are alternate forms of treatment for cancer, and their effectiveness is still being studied—despite the promising results and relevant success stories.


Fenbendazole for Cancer


How To Use Fenbendazole for Cancer: It can be taken as a single dose in the morning, with or without food.

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