Fenbendazole Cancer Success Stories: 239 Case Reports Compilation (September 2025 Edition)

Contents:
  • Editor's Preface
  • Introduction
  • Fenbendazole Case Series Compilation (alphabetical)
    1. Breast Cancer Success Stories (48 cases)
    2. Brain Cancer (including Glioblastoma) (7 cases)
    3. Bile Duct Cancer (Cholangiocarcinoma)
    4. Bladder Cancer Success Stories (7 cases)
    5. Cervical Cancer (2 cases)
    6. Colorectal Cancer (including Appendix cancer) (32 cases)
    7. Esophageal and Stomach cancer (11 cases)
    8. Endometrial Cancer (6 cases)
    9. Gastric (Stomach) cancer (refer to Esophageal and Stomach Cancer)
    10. Head and Neck Cancer (13 cases)
    11. Kidney Cancer Case Series (12 cases)
    12. Liver Cancer (HepatoCellular Cancer) (3 cases)
    13. Lung Cancer (20 cases)
    14. Leukemia (2 cases)
    15. Lymphoma (10 cases)
    16. Melanoma (refer to Skin Cancer)
    17. Multiple Myeloma (3 cases)
    18. Myelodysplastic Syndrome
    19. Oral Cancer
    20. Ovarian Cancer (6 cases)
    21. Pancreatic Cancer (23 cases)
    22. Prostate Cancer (32 cases)
    23. Sarcoma (4 cases)
    24. Skin Cancer (10 cases)
    25. Throat Cancer
    26. Thymus cancer
    27. Thyroid Cancer (2 cases)
    28. Turbo Cancer
    29. Uterine cancer (6 cases)
  • Conclusion

It is important to acknowledge that the Fenbendazole protocol is not a universal cure for cancer. We do not advocate for or against any treatment—whether conventional (such as surgery, chemotherapy, radiation, immunotherapy), alternative, complementary, or adjunctive approaches. Our focus remains on effective and safe strategies that may offer hope and improve outcomes for patients.

Fenbendazole Cancer Success Stories

This article is not intended to be your definitive guide but rather a step in your journey toward the best possible health. It emphasizes that fenbendazole and other approaches may form part of a comprehensive, multi-modal cancer treatment strategy tailored to your individual needs. We encourage you to seek additional resources, ask questions, and explore all available options, including conventional treatments such as surgery, chemotherapy, radiation, targeted therapy, immunotherapy, and hormone therapy, as well as emerging modalities. Personalized treatment plans developed with your healthcare team offer the best chance for effective management and improved outcomes.

Editor's Preface

Introduction: From a Handful to Hundreds

The mission of this compilation is to inspire and encourage patients who find themselves in similar circumstances, especially those who have felt abandoned or overlooked in their medical journey. What started as a small collection of case reports has grown into more than 200 stories of resilience, hope, and determination—gathered from diverse independent sources to remind patients that they are not alone.

The Conventional Perspective on Cancer Treatments

Before addressing inflammatory claims in mainstream fact-checking articles and the 'misinformation' labels applied by social media platforms, let’s explore the conventional perspective on cancer, as typically presented by medical specialists and major media outlets:
  • We need larger, high-quality studies before making formal recommendations.
  • This is medical misinformation! There is no evidence that fenbendazole works, or its effectiveness is not scientifically proven.
  • Case series are 'anecdotals' (not necessarily true or reliable; weak evidence). There are no randomized controlled trials* on fenbendazole and cancer in humans.
  • This is ‘false hope.’ If something sounds too good to be true, it probably is.

*RCT methods are 50+ years old... RCT (Randomised Controlled Trial) is a form of scientific experiment used to control factors not under direct experimental control. RCT is considered the 'gold standard' for human research. RCTs were recognised as the standard method in the 20th century. First 'blind experiment' was in 1784 and first published RCT was in 1948 (Wikipedia). The Randomised placebo Controlled Trial (RCT) method for hard evidence is a very expensive and impractical model when it comes to something as complicated as cancer. Most drugs are designed to affect one part of cancer and not the other parts of cancer or even the root causes of cancer. To understand more of this concept, check out 'hallmarks of cancer'. The randomized placebo-controlled trial (RCT)* is widely regarded as the gold standard for generating high-quality evidence in medicine. However, when it comes to cancer, the RCT model is often prohibitively expensive, time-consuming, and sometimes impractical. See "Randomised controlled trials (RCTs), are often costly, slow, and logistically challenging - ChatGPT". RCTs typically focus on evaluating a single intervention under controlled conditions, which does not reflect the complexity and heterogeneity of real-world cancer care (12). 

Cancer is a multifaceted disease involving numerous biological pathways and mechanisms, as described by the “hallmarks of cancer”—a conceptual framework that outlines the diverse capabilities cancer cells acquire during tumor development and progression. 

“The cure for cancer? It all started with a single case study.”

Why You’re Reading This Here—Not in Mainstream Media

Most mainstream doctors will dismiss fenbendazole as ineffective. But have they actually read the case reports presented in this article? Most likely, they have not. And if they have, they may dismiss these case reports as biased or of low-quality evidence—implying that more than 180 patient testimonials are simply false. Yet when faced with a stage 4 cancer diagnosis for themselves or a loved one, many may revisit this article for a second look.

You may have also found this article through a social media link rather than mainstream news outlets or major search engines. Why is that?

Unlike traditional platforms, social media allows the rapid sharing of niche or under-represented stories—giving content like this a chance to reach those who might otherwise miss it.

When diagnosed with cancer, most people rely on discussions with family members and doctors. However, they often encounter conflicting recommendations—some professionals support exploring fenbendazole, while others strongly oppose it.

Navigating Fact and Fiction

So, what’s fact and what’s fiction? The answer depends on science and research. However, science can be biased, manipulated, or selectively presented to fit a particular narrative. That’s why it’s crucial to do your own research in consultation with a trusted doctor. Many media references rely on outdated studies or cherry-picked data that align with a specific viewpoint.

Note: Do we have any conflicts of interest? Are we trying to sell you something? The information in this article is provided completely free of charge—there’s no need to purchase anything or make any payment to us.

Real Stories, Real Hope

Many people immediately dismiss the potential of fenbendazole when they learn it is “dog medicine.” That initial reaction is overcome when the success stories regarding fenbendazole and cancer are told including the lack of serious side effects.

The testimonials you are about to read are from individuals who have bravely shared their experiences in the hope of inspiring and uplifting others. These are raw human accounts, unfiltered by gatekeepers—not peer-reviewed studies—but they offer insights and clues that may be valuable to those searching for better options.

It's important to note that many of the cases below involve stage 4 cancers that have failed conventional treatments. Achieving a Complete Response (CR) or No Evidence of Disease (NED) is uncommon, especially after chemotherapy failure. Complete responses in stage 4 cancers are rare and represent exceptional outcomes given the advanced disease and limited treatment options at this stage.

If you or a loved one have a matching cancer subtype, it can be especially compelling to consider trying fenbendazole and/or ivermectin —particularly when dealing with aggressive cancers that have low survival rates, such as triple-negative breast cancer or stage 4 pancreatic cancer.

The Case for a Precautionary Approach

According to The Cochrane Review’s editor-in-chief, Karla Soares-Weiser (source):

“Lack of evidence of effectiveness is not evidence that the interventions are ineffective… Waiting for strong evidence is a recipe for paralysis. Public health officials must take measured gambles, based on circumstantial evidence from the reviewed studies and other sources. When protecting the public from harm, they must act even when evidence is uncertain (or not of the highest quality), particularly when the harms and costs of such action are likely limited.”

Even if the chance of fenbendazole helping is small, individuals have the right to explore it as an option.

Dr. John Campbell, a health educator with over 3 million YouTube followers, shared (video) a compelling perspective in his video on fenbendazole and ivermectin for cancer:

“People have the right to try. They could try these drugs... and we could track them over time. We could build national cohorts of tens of thousands of patients in no time… then hand it over to statisticians to analyze the data and uncover the mathematical truth. This could be done, and in my view, it should be done.” - Dr John Campbell

"When you've tried everything, sometimes it's the unexpected that brings the miracle." - One Day MD

A Final Word of Encouragement

If you have stage 4 cancer, don’t lose hope. Your story could be the next inspiring success.

“N=1 is the future.”Michael Snyder, Stanford Medicine (source)

Instead of relying solely on large-scale studies, case reports focus on individuals—allowing people to directly assess how specific interventions affect their unique health profiles in the real world. As Snyder told The Epoch Times“We are all different, and now we can collect a lot of data on a single person or a few individuals to make very specific recommendations.”

In the end, science evolves. Until then, the right to try belongs to you.

Introduction

Access to effective, cancer-specific therapies remains limited, particularly in low- and middle-income countries where cancer survival rates lag behind those in high-income settings due to inadequate funding and infrastructure (sourcesource). This has led to increased interest in repurposing existing drugs as more affordable alternatives. Exploring such options may provide valuable insights and potential solutions for expanding treatment accessibility, warranting further scientific investigation.

Traditional cancer therapies—including surgery, chemotherapy, radiation, targeted therapy, and immunotherapy—have relatively low documented survival rates and outcomes for advanced, metastatic and stage 4 cancers:
  • Stage 4 Breast Cancer 5-year relative survival rate: 26% (distant/metastatic) (2).
  • Stage 4 Colorectal Cancer 5-year survival rate: 13% (distant) (2).
  • Lung Cancer (Stage III NSCLC): Addition of immunotherapy after chemo-radiation increased 3-year survival to 52% versus 44% for chemo-radiation alone in a large US study (JAMA 2022).
One emerging area of interest in recent years is the potential use of fenbendazole (FBZ) as either a standalone treatment or a complementary therapy alongside conventional treatment for various forms of cancer. FBZ is a widely available and cost-effective deworming medication primarily used in veterinary medicine, commonly sold in pet stores and through commercial websites. Its accessibility and affordability have contributed to growing public interest in its possible anti-cancer properties.

Fenbendazole, often referred to as FenBen, is an anti-parasitic or de-worming medication initially developed to eliminate roundworms and pinworms in animals and humans. 

Fenbendazole is a broad spectrum anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits, most reptiles, freshwater shrimp tanks as planaria and hydra treatments, as well as seals.

Common brand names include Pancur, Panacur C and Safe-Guard.

Note: In everyday conversations within the fenbendazole communities, you might encounter Fenbendazole referred to as Phenbendazole, Panacur or SafeGuard. This interchangeability is representative of the common use of the trademarked name; it signifies a consensus within these circles that these terms denote the same medication. Fenbendazole is the active ingredient in all these products. Molecular formula for fenbendazole is C15H13N3O2S.

Although first introduced in 1961, it wasn't until 2009 that FenBen's potential as a cancer treatment was discovered during a glioblastoma (GBM) study at Johns Hopkins University. Since then, numerous case reports have demonstrated FenBen's effectiveness in treating various cancers, including lung, kidney, liver, breast, prostate, melanoma, bone, ovary, colon, and brain tumors. A cancer treatment method known as the Joe Tippens Fenbendazole Protocol has also been gaining rapid interest over the past years.

Given the complexity of cancer treatment, it is crucial for patients to consult a specialized oncology team to determine the most appropriate course of action for their specific diagnosis.
 
Despite numerous anecdotal reports and media coverage suggesting that FBZ may be effective in treating metastatic cancer, there is currently not enough clinical literature supporting its use as an anti-cancer agent. 

This work-in-progress paper aims to compile anecdotal success stories and case reports to help establish a stronger scientific foundation for further investigation of fenbendazole (FBZ) as part of a potential combination therapy for cancer.


fenbendazole dosage for cancer in humans
Fenbendazole dosage for Cancer in Humans


Fenbendazole for Cancer Case Series Compilation

The following success stories were gathered from various web and social media sources, providing anecdotal, crowd-sourced information.

The list of fenbendazole related cancer case reports below is organised alphabetically by cancer type.

Notes: 
  • Some cancer types have more than 10 case reports, so we’ve created dedicated articles for each to make updates and management easier. To view the complete set of case reports, click “Read More” under the relevant cancer type.
  • This is a lengthy article. To quickly find the specific cancer type you're looking for, use "Command + F" (Mac) or "Control + F" (Windows) to search the page.

1. Breast Cancer Success Stories (44 Cases)

The compilation includes over 40 ivermectin and fenbendazole for breast cancer case reports, with selected cases summarized below. Full details are provided in this article: Fenbendazole, Ivermectin and Mebendazole for Breast Cancer Success Stories.

2. Brain Cancer Success Stories (7 cases)

Case No. 7 - 2025: 66 year old Ontario man with Glioblastoma (unmethylated)

Dr William Makis shared on X/Twitter (June 2025):

IVERMECTIN and MEBENDAZOLE* Testimonial - 66 year old Ontario man with Glioblastoma (unmethylated) reports after 5 months - no recurrence A Glioblastoma success story! 66 year old Ontario man with Glioblastoma (unmethylated) For 5 months, the patient was on:
  • Ivermectin 168mg/day
  • Mebendazole 1500mg/day
  • Melatonin 500mg/day
RESULT: No recurrence on follow-up imaging! Glioblastoma (GBM) is a lethal disease. At least in part, the recurrence of GBM is caused by cancer stem cells (CSCs), which are resistant to chemotherapy Ivermectin targets and kills Cancer Stem Cells! The question is whether we can completely prevent recurrence of Glioblastoma (unmethylated) over the long term. I believe we can. But we have to prove it with long term studies. That's next.

*Note: Although the fenbendazole and mebendazole are very similar in effectiveness at higher doses, Mebendazole has superior brain cancer cell killing at lower loses compared to Fenbendazole. So for Glioblastoma, it’s Mebendazole if you can get it. Otherwise, you can't go wrong with Fenbendazole. It's still almost as good. (source)


Case No. 6 - 2025: 74 year old Canadian man with Glioblastoma

Dr William Makis shared on X/Twitter (June 2025):

IVERMECTIN and MEBENDAZOLE - 74 year old Canadian man with Glioblastoma gives an exciting update after 3 months! Do you want to hear a brain cancer success story? Of course you do! 74 year old Canadian man with Glioblastoma In early March 2025 we started:
  • Ivermectin 1.5mg/kg/day
  • Mebendazole 1500mg/day
  • CBD Oil 100mg/day
The patient was on this regimen for 3 months (and if you count the Ivermectin and Fenbendazole they started on their own in early February, then 4 months). From the patient: "he recently had his first MRI since chemo and radiation begun - there were no abnormal changes - no abnormalities - no new artifacts Overall, both our family and the oncologists were extremely happy to not see any visible growth or changes." "First off, thank you for your work and services, I have zero doubt that the results would have been different if we didn’t have your guidance." I do believe that Glioblastoma recurrence could be eliminated with a repurposed drug regimen that includes Ivermectin and Mebendazole. Of course, now we have to prove it with long term follow-up and publish it. Remember, this patient was quoted a life expectancy as low as 6 months as Glioblastomas are notorious for recurrence despite best conventional cancer treatment. We are 4 months in and the patient is CANCER FREE.


Case 5 - 2025: Brain Cancer Testimonial from Brazil

"We applied your protocol plus methylene blue to a friend with brain cancer...started in beginning of February 2025...she is cancer free now!

"Getting more details...story developing.

Ivermectin. Mebendazole. Methylene Blue.




Case 4 - 2025: 36 year old California woman with multifocal Grade 4 Astrocytoma


Dr William Makis shared on X/Twitter (May 2025):

IVERMECTIN and MEBENDAZOLE Testimonial - 36 year old California woman with multifocal Grade 4 Astrocytoma is now improving after 2 months! I get asked for Brain Cancer stories ALL THE TIME Here is one! (More are coming soon) STORY: 36 year old California woman was diagnosed with multifocal Grade 4 Astrocytoma (7 brain lesions) in January 2025 In late January 2025 we started:
  • Ivermectin 1mg/kg/day
  • Mebendazole 1500mg/day
RESULTS after 2 months: "We received results of her MRI yesterday...her oncologist informed us that her tumors are at the very least stable and appear to be shrinking" “They were absolutely shocked as they didn’t seem to have much hope for her prior to this as her cancer was aggressively progressing prior to your treatment”

"If you are unsure how big of a role an Ivermectin/Fenbendazole/Mebendazole protocol plays, always look at the reaction of the Oncologists. They rarely hide their shock. Brain tumors are difficult to treat in general, but the Ivermectin & Mebendazole combination is starting to make a huge impact in this area." - Dr William Makis


Case 3: Stage 4 brain cancer terminal and on radiation and chemo

Doverschoice posted on X/Twitter in April 2025:

My mother had the vaccine and one booster stage 4 brain cancer terminal and on radiation and chemo. Have tried to reach out to William for some time to get some help on what to give her!

Dr William replied (April 2025):

Mebendazole, CBD, Ivermectin would be my top 3.


Case 2: 41 year old Canadian man with Grade 3 Oligodendroglioma Brain Cancer

Dr William Makis shared on X/Twitter (Feb 2025):

IVERMECTIN and FENBENDAZOLE Testimonial - 41 year old Canadian man with Grade 3 Oligodendroglioma Brain Cancer opts out of chemo & radiation - doing extremely well! 

STORY: 

41 year old Ontario man had an aggressive Grade 3 Oligodendroglioma that was mostly resected in early June 2024. After surgery, he opted out of chemo and radiation therapy. Sep.2024 MRI showed “residual parenchymal tumoral component” 4.5x4.1x3.6cm.

We started an aggressive Makis Ivermectin Cancer Clinic Protocol: 
  • Ivermectin 1mg/kg/day increasing to 2mg/kg/day 
  • Fenbendazole 888mg/day
He had a follow-up MRI 3 months later: RESULTS: The Radiologist couldn’t find the residual tumor! From the patient: 
"Thank you so much. I don't know how else to put it. This is not a big deal...its THE deal. A cure for "terminal" brain cancer. The implications are mind-blowing and its sad so few people know about these options." 
"Keep up the good fight please!"


Case 1: Male with Glioblastoma

Case sharing by Michelle Wright (X/Twitter):

The reading of the results has been posted!! There is a whole lot that I DON’T understand, but I can understand enough to see that THERE HAS BEEN IMPROVEMENT!!  I appreciate all of the prayers and well wishes!  For anyone that isn’t up to date- my Dad was diagnosed with Glioblastoma in April of this year. He had completed one full round of chemo and radiation, and at the beginning of August he was not well. I won’t go into detail. However, I had been doing a lot of research and one of the AWESOME pages I found here was @JohnDParody  I went with a protocol that I felt was best and got my Dad started on a journey with Ivermectin and Fenbendazole. He HAS continued his chemo treatments, but I 100% believe it has been that being used in combination with the Ivermectin and Fenben that has gotten him where he is today. I’ve been here, and I’ve watched him improve daily. I do not have pictures of the scans themselves, because they’re not posted on the portal. But if anyone would like to compare it to any of his previous readings, I can get those as well. I’m going to go celebrate with my Dad.



Note:

Although the fenbendazole and mebendazole are very similar in effectiveness at higher doses, Mebendazole has superior brain cancer cell killing at lower loses compared to Fenbendazole. So for Glioblastoma, it’s Mebendazole if you can get it. Otherwise, you can't go wrong with Fenbendazole. It's still almost as good. (source)

Albendazole is also recommended for brain related cancers or brain spread, as it can cross the blood-brain barrier. (source)


3. Bile Duct Cancer (Cholangiocarcinoma)

Dr William Makis shared on X/Twitter (December 2024 update):

IVERMECTIN and FENBENDAZOLE Testimonial - 53 year old Stage 4 Cholangiocarcinoma Cancer patient with 15cm tumor declared "Cancer Free" after reaching out to me 14 months ago!! This is a very special story. 53 year old Canadian Cancer patient diagnosed with Stage 4 Cholangiocarcinoma, metastatic to liver in March 2023. Multiple lesions, largest 15cm. Patient had chemo and reached out to me in October 2023. "I was taken off the bag of immunotherapy because the tumour didn't shrink" "Second oncologist...was worse than the oncologist I have now...told me my supposed mortality chart and to watch for "the end" because I'd be lucky to make it to summer (2024)"

"I'm terrified...I'm losing hope" I replied on Nov.3, 2023: "Don't lose hope..
  • Ivermectin is 1mg/kg/ or 2mg/kg daily
  • Fenbendazole is typically 444mg daily
  • Melatonin is 100mg-300mg daily" (see note below)
Life went on...then I get an email in July 2024: "I'm still here thanks to you :)"

We went to work. Oncologists were pressuring to give her more and more chemo. In November 2023, she had started Fenbendazole 444mg (Panacur) and Melatonin 100mg

In August 2024 we added 150mg of Ivermectin or 2.5m/kg/day, and CBD-THC Oil. You heard that right. Ivermectin 2.5mg/kg/day. And then... December 12, 2024: "Cancer Free".

Note: "Melatonin induces apoptosis in cholangiocarcinoma cell lines by activating the reactive oxygen species-mediated mitochondrial pathway" (source)






Related: Adjuvant Chemoradiation and Immunotherapy for Extrahepatic Cholangiocarcinoma and Gallbladder Cancer (2025 JAMA Oncology)

4. Bladder Cancer Success Stories (7 cases)

Case 7: 65 year old patient from Sweden with recurrent Bladder (urinary) Cancer

Dr William Makis shared on X/Twitter (April 2025):

IVERMECTIN and FENBENDAZOLE Testimonial - 65 year old patient from Sweden with recurrent Bladder Cancer becomes "Cancer Free" for the first time in 2.5 years! Cancer patients come to me from around the world. This time: Sweden. "I am 65 years old. I was diagnosed with bladder cancer 2 years ago. I have follow-up visits every 3 months and then relapse all the time". This time he did something different, he came to my Ivermectin Cancer Clinic. We started some Ivermectin & Fenbendazole 3 months later... "April 3, it was time again for my cystoscopy of the bladder...doctor said before the examination that now I have to start chemotherapy" 
"This time they did not find a single tumor!!! After the examination, the doctor said I could forget about the chemo, but she couldn't understand how I was suddenly cancer-free" 
"That was absolutely amazing news, and I want to thank you for helping me get cancer-free. Without your help, it wouldn't have been possible".


Case 6 - 2025: 75-year-old man with Stage 4 urothelial bladder cancer with metastases to multiple organs


Description: Shared on March 24, 2025, by @MakisMD, this details a 75-year-old man with Stage 4 urothelial bladder cancer with metastases to multiple organs. He reportedly showed dramatic improvement on PET/CT scans after using ivermectin and fenbendazole.

TREATMENT 
  • Padcev and Keytruda 12/23/2024 to 3/10/2025 
  • Fenbendazole 222mg/d 1/3/2025 to 2/19/2025 
  • Ivermectin 30mg/d 1/20/2025 to 2/19/2025 
  • Fenbendazole 1500mg/d (Makis Protocol) 2/19/2025 - 3/10/2025 
  • Ivermectin 1mg/kg/d (Makis Protocol) 2/19/2025 - 3/10/2025
Related: EV-302: Long-term subgroup analysis from the phase 3 global study of enfortumab vedotin in combination with pembrolizumab (EV+P) vs chemotherapy (chemo) in previously untreated locally advanced or metastatic urothelial carcinoma (la/mUC)


Case 5: Papillary Urothelial Bladder Cancer

Dr William Makis shared on X/Twitter (Feb 2025):

IVERMECTIN and FENBENDAZOLE Testimonial - Bladder Cancer (Papillary Urothelial Carcinoma) - "Cancer Free for the first time since 2014" "Dr.Makis...I'm writing to inform you about my latest bladder biopsy which was negative. Since 2014, every pathology returned was positive for low-grade papillary urothelial tumors, until now" "I started taking Ivermectin 1mg per kilo. Then somehow I was able to get in touch with you to ask if I should do anything else. You mentioned 444mg of Fenbendazole". "Cancer Free for the first time since 2014"
  My Take… "I believe this is my first bladder cancer testimonial. Can you imagine helping someone become "cancer free" for the first time in 10 years?"  Recent research backs the use of Ivermectin + Fenbendazole in bladder cancer: 2024 - Fan et al - Ivermectin Inhibits Bladder Cancer Cell Growth and Induces Oxidative Stress and DNA Damage.
  “Our study showed that in vitro and in vivo, Ivermectin inhibited the growth of bladder cancer cells. In addition, Ivermectin could induce apoptosis, ROS production, DNA damage, and activate ATM/P53 pathway-related proteins in bladder cancer cells. Conclusion: According to these findings, Ivermectin may be a potential therapeutic candidate against bladder cancer due to its significant anti-cancer effect.” 2022 Tung et al - Ivermectin induces cell cycle arrest and caspase-dependent apoptosis in human urothelial carcinoma cells “Ivermectin inhibited growth, regulated the cell cycle, and induced apoptosis in human UC cells. It also induced the activation of both extrinsic and intrinsic caspase-dependent apoptotic pathways. Further investigation revealed that ivermectin induced apoptosis in UC cells is mediated via c-Jun N-terminal kinase signaling. Herein, we demonstrated that Ivermectin can be used as a new therapeutic agent for treating UC cells.” 2021 Chiang et al - Fenbendazole Enhancing Anti-Tumor Effect: A Case Series “A 63-year-old Caucasian female presented with increasing lower urinary tract symptoms and hematuria. CT imaging revealed a 7.5 cm right lateral bladder mass with extension to the right pelvic sidewall and right-sided hydronephrosis requiring percutaneous nephrostomy. There was no evidence of metastatic disease, consistent with clinical T4 tumor. Transurethral Resection of Bladder Tumor (TURBT) demonstrated a large necrotic mass with pathology confirming urothelial carcinoma with 85% squamous and 2% sarcomatoid histology. She was treated with Accelerated Methotrexate, Vinblastine, Doxorubicin, and Cisplatin (AMVAC) for 6 cycles over the course of 4 months along with concurrent Fenbendazole (FBZ) 1 gram three times weekly. Follow-up CT revealed no evidence of disease with minimal residual thickening in the right inferior bladder wall. She declined to proceed with cystectomy and remains on surveillance with no evidence of progression.”
  • Ivermectin 1mg/kg/day.
  • Fenbendazole 444mg/day

Case 4

Wonderful!

Yes, I take three Ivermectin and one Doxycycline when I get up in the morning with a large, 16 oz glass of water. I wait an hour and have some light food (organic eggs and avocado slices, kimchi for example).

At around 5 p.m. I take three Fenbendazole with a light meal with little carb and higher fat/protein.

I started protocol on 11/11/23.

I had surgery on the 22nd of November for the removal of three cancerous tumors from my bladder(my third surgery, and will have an MRI in two weeks to see if muscle invasive as was before.)

As a result of my 11/11 initiation protocol I noticed an area the size of a dime below my left clavicle disappear ( a skin lesion that I had had for 2-3 years that was raised and would be prone to slight bleeding when rubbed too hard with a towel) to now virtually nothing.

I know this protocol was the reason for this healing. Thrilled! I feel this regime is doing the same to any cancer I may have left in my bladder area. I’ll keep you posted.

I am so grateful to you.

Thank YOU!!!!!

Best, K.

(Please note that K. is using a modified ketogenic diet to starve the cancer of sugars and carbohydrates, which we know is what feeds cancers. An important article on this subject is forthcoming, along with a new product that not only serves as a sugar replacement, but, also, helps eradicate both cancers and diabetes.)


Case 2: Plasmacytoid urothelial (bladder) carcinoma (PUC) (Updated February 2023)

Condition: Plasmacytoid urothelial (bladder) carcinoma (PUC)

July 2022:
I was told from the pathologist report that I had Plasmacytoid cancer after they removed two tumors from my bladder. I was informed that this type of cancer is very rare and is highly aggressive and that it doesn’t respond to chemo or radiation and that I was a candidate for bladder removal. I asked how long I had to live and they said they couldn’t tell me for sure maybe a year maybe 6 months they didn’t know how it was going to react. The it was between me and God!!

I walked out with my death sentence in my hand on the papers they gave me of the report an letter from the Dr. It was a difficult time, but I have been in recovery from alcoholism an drug addict for 10 years as of the 2nd of April 2022, this was on April 22nd 2022. I refused to accept it I thought that there must be something I could do I prayed to God for direction!

I thought about contacting MD Anderson and donate my body to them for trials they wanted money up front!! I post my condition on face book so my friends would know, I begin to get calls and text about people using Fenbenzadole found in Dog Dewormer so I googled it and found it.

I started taking Fenben last part of April 2022, and it is July 19th now an I’m still taking it. I quit my job came back to Oklahoma and contact OU Cancer hospital. I went July 15th an had CT’s an scans done to see what the cancer was doing an how it had spread. The Dr. came in and said he couldn’t see any cancer anywhere in my body that had spread and that he couldn’t see any cancer anywhere else or any Tumors or cancer in my Bladder!!!

I take Fenbenzadole every day I have changed my diet I eat only fish an chicken no meat with blood in it, I drink hot lemon juice once a day I eat all kinds of berries an fruits, take vitamins an I believe that that God has healed me through this medicine an I pray that you don’t give up any do what you must if it healed me then maybe it can heal you too.

Update – February 2023:

Yesterday I received my PET scan report. No signs of any METASTATIC DISEASE ANYWHERE! MRI of my brain was NORMAL, NO SIGNS OF CANCER OR TUMORS ANYWHERE !! These factors prove that FENBENZADOLE AND TURMERIC CURCUMIN AND CHANGES IN MY DIET HAVE KILLED THIS RARE AND HIGHLY AGGRESSIVE CANCER WITH KNOW KNOWN CURE ALONG WITH FAITH IN A GOD THAN CAN PERFORM MIRACLES AND STUN THE MEDICAL PEOPLE WHO ARE IN DENIAL ABOUT THIS DRUG!! NOW must continue to follow this path and make the changes to keep cancer free and use Fenbenzadole as I must. Thank you and never give up !!!

Listen here for an interview with Earnest: Earnest Best was Given the Death Sentence and He Didn’t Take It.
 

Case 1: High grade, Urothelial carcinoma (December, 2021)

From high grade, urothelial carcinoma to no evidence of disease (NED) in less than a year – thanks to fenbendazole! I was diagnosed late 2021 with tumors the size of my thumb growing on the inside of my uterus. The tumor was removed as soon as possible with several immunotherapy BCG treatments that followed (delivers immunotherapy drugs directly to your bladder through a catheter).

Related: 
See also Kidney Cancer success stories (below)

5. Cervical Cancer Success Stories (2 cases)

Case 2: SCNECC (Small Cell Neuro-Endocrine Carcinoma of the Cervix)

@dori61318179 shared on X in May 2025 (source):

"Our daughter was diagnosed with SCNECC And was told she had 30% chance to live three years with traditional treatment. We immediately started her on your protocol, and after only four months, she is completely cancer free! God bless you, sir!"


Case 1: 50s year old Stage 4 Cervical Cancer patient (October 2024 and November 2024 Update)

November 2024 - Case study from Dr William Makis (X/Twitter):

IVERMECTIN & FENBENDAZOLE Testimonial - 50s year old Stage 4 Cervical Cancer patient - CA125 drops 46% in 2 months on high dose protocol! 

50s year old Stage 4 Cervical Cancer metastatic to liver patient (USA) 

We started a Protocol early Sep.2024: Ivermectin 2mg/kg/day (split over 2 doses) Fenbendazole 2000mg/day (split over 2 doses) Continue ongoing Tivdak (Tisotumab vedotin) (there was no improvement in CA125 on it so far) 

(we switched Fenbendazole brands after a few weeks, when CA125 hit 99.1) Results: 46% drop in CA125 in 1.5 months ! 

The picture of the CA125 trend is worth a thousand words!






October 2024 - Case study from Dr William Makis (X/Twitter):

IVERMECTIN & FENBENDAZOLE TESTIMONIAL - Stage 4 Cervical Cancer patient sees first dramatic drop in blood cancer markers after a few weeks of adjusting Ivermectin & Fenbendazole doses!

We started a High Dose Ivermectin/Fenbendazole Protocol beginning of September and after 4 weeks the CA125 value hadn’t changed, it had gone from 91U/mL to 99.2U/mL which I considered stable but a little bit stubborn. 

We were a bit slow getting the Ivermectin up, so I increased it by 30% increments to +100%.
We also switched up and mixed the Fenbendazole Brands! And the next CA125 dropped by 30% for the first time! 

In just 3 weeks! You have to be able to adapt and fine-tune. Ivermectin really does work at higher doses. But sometimes it’s not easy to get there. And for Fenbendazole, you CANNOT be married to a brand. Mix things up. If you feel a brand is not working, add a completely different brand! DON’T BE AFRAID TO CHANGE BRANDS! That’s the lesson here. Be flexible.

"Switched from Happy Healing to Sanare Lab Fenbendazole"

6. Colorectal Cancer Success Stories (29 cases)

Read More: Fenbendazole and Ivermectin for Colorectal Cancer (29 cases)

7. Esophageal and Stomach (Gastric) Cancers (11 cases)


8. Endometrial (Uterine) Cancer (6 cases)

Cases 3 - 6: Endometrial (Uterine) cancer

Dr. William Makis shared on X (Twitter) in March 2025:

IVERMECTIN and FENBENDAZOLE Testimonials - ENDOMETRIAL Cancer - Four patients from Canada, USA and Germany respond. This is also a world's first! I had a pile of good responses from my Endometrial Cancer patients so I thought it would make sense to put some together for a short article. Summary: I have seen Stage 4 Endometrial cancers respond to both Ivermectin and Fenbendazole. In this article I present four cases: Case 01: 88 yr old Female (Germany) Stage 4 Endometrial Ca, on Fenben CA19-9 dropped from 800 to 90, added Ivermectin and CA19-9 dropped to 80. That’s 90% decrease in CA19-9 Cancer marker. Case 02: 83 yr old Female (Canada) High Grade Serous Endometrial Ca Stage 4, on Ivermectin 1mg/kg/day and Fenben 888mg/day, omental metastasis decreased in size after 2 months. Case 03: 63 yr old Female (USA) High Grade Serous Endometrial Cancer, had surgery in Sep.2024, on Ivermectin 1mg/kg/day and Fenbendazole 888mg/day, “Cancer Free” with negative PET/CT in Jan.2025 after 5 months.

Case 04: 74 yr old Female (Canada) Stage 4 Endometrial Ca, CA125 dropped from 659 to 68 to 44, after 3 months.

The use of Ivermectin and Fenbendazole in Endometrial Cancer has never been published, so my Ivermectin Cancer Clinic is breaking new ground here.
There is one paper that describes Ivermectin inhibiting the WNT pathway, which is key in the proliferation and growth of certain cancers including ENDOMETRIAL. 2014 Melotti et al: The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer. "A variety of sporadic human cancers have been found to harbor hyperactive canonical WNT signaling" "Other cancers also show an active canonical WNT pathway; these include carcinomas of the lung, stomach, cervix, endometrium, and lung as well as melanomas and gliomas"

"We report that Ivermectin inhibits the expression of WNT‐TCF targets" "Ivermectin inhibits the proliferation and increases apoptosis of various human cancer types" "In vivo, Ivermectin selectively inhibits TCF‐dependent, but not TCF‐independent, xenograft growth without obvious side effects" "Given that Ivermectin is a safe anti‐parasitic agent used by > 200 million people against river blindness, our results suggest its additional use as a therapeutic WNT‐TCF pathway response blocker to treat WNT‐TCF‐dependent diseases including multiple cancers." This is why I can often succeed where the top Cancer Centers in the United States fail. Oncologists don't look at Ivermectin research. In fact, they do everything to avoid it. It's not that they don't know. They don't want to know. Yes, some of this Ivermectin research is obscure, not easy to find, and not easy to read. But it's there. Endometrial cancer responds to Ivermectin, and we have an idea why (Ivermectin blocks a key cancer proliferation pathway called the WNT pathway that is active in Endometrial and Cervical cancers).


Case 2: 81-yr-old female with recurrent Endometrial Uterine Cancer (May, 2023)

My 81 yo mother, Virginia, found out she had recurrent Endometrial Uterine Cancer back in Sept 2022. Stage 4 and Mets to abdominal area, lymph nodes, chest cavity and lungs. Radiation was not an option and she opted out of chemo, which would have only bought her a few extra months but would have made her very sick and weak. The doctor put her on a Hormone Blocker to keep it from growing any more. (But if in the lymph nodes, does it really stop it??) The Dr. sent her home to be under Hospice care for the remainder of her short time left on this earth.

I was not ready to accept this!! (Plus, my father has dementia and desperately needs her!) I prayed to God to give us wisdom and guidance. Within 24 hrs., three people approached me about the Joe Tippen Protocol, which I had never heard of at that time. I figured I might ought to listen so I googled and got sucked in! I started learning everything I could learn about it. Then I presented it to mom. She said, “Well, what do we have to lose!?!?”

So, in Oct, through prayer and God’s guidance, I got her up and running on “things” (FenBen, Tudca, Serrapetase, Tumeric, High-Dose Melatonin, Turkey Tail, Apricot Seeds, drinking Baking Soda water, and rubbing on Frankincense). She has been very weak this whole time so we weren’t sure if it was working or not. We planned her funeral, etc….

Then, 5 mo later, her Dr insisted she have another scan. She was very apprehensive but agreed. We (including the dr) were blown away by the results!!! The tumors are either gone or have shrunk considerably!!!! (All but ONE, which basically has stayed the same). All of the ascites (malignant fluid all in her Ab area) was GONE!! The Doctor patted himself on the back but WE PRAISE GOD AND FENBEN!!!

We take one day at a time and hope and pray for the best for years to come but, for today, things are going well!!! (Other than her weakness)

*UPDATE: I added her protocol as a picture so take notice for those interested.





Case 1: Stage 4 Endometrial carcinoma (January, 2023)

Condition: Endometrial carcinoma

In May 2021 I was diagnosed with stage IV endometrial carcinoma. I went through 6 months of hard chemo and 12 months of Maintenance chemo. March 2022 I started fenbendazole working up to 2000 mg a day, along with other supplements. I had a consult this month with Zahara, and she recommended tweaking a few things and adding a few more supplements. I worked hard on my mindset and made sure I surrounded myself with positivity. I received the best news today I could hope for. No evidence of active disease. Never give up!



Related: Nivolumab and Ipilimumab (Immunotherapies) Combination Treatment in Advanced Ovarian and Endometrial Clear Cell Cancers

9. Gastric (Stomach) Cancer: Fenbendazole and Ivermectin


10. Head and Neck Cancer Success Stories (13 cases)

Case 13 - 2025: Head and Neck Small squamous cell Carcinoma stage 3+ (Left tonsil cancer with extension to the posterior tongue and involvement of lymph nodes on the left side of the neck)

Published in Jan 2025 on Brighter-Works Cancer Alternatives Substack:

In December of 2023, I received a life-altering diagnosis: cancer that had originated in my left tonsil and had metastasized to the back of my tongue and into the lymph nodes on the left side of my neck. Faced with the oncologists' recommendation of undergoing 37 sessions of radiation and chemotherapy, I chose to forge my own path by developing a personalized treatment protocol. I firmly believe in the potential of natural products and their ability to support our bodies in healing, but similar to pharmaceuticals, some elements of my protocol, such as Ivermectin, can also present opportunities for abuse or misuse. I cured my cancer with the protocol and my faith. But i did so using smaller doses.

Yes, I utilized Ivermectin alongside Fenbendazole on a daily basis and tailored my dosage to what I felt was appropriate for my specific needs. Concurrently, I incorporated CBD products into my regimen through a tincture I created, along with a carefully considered selection of supplements and dietary adjustments. Importantly, I did not abuse Ivermectin by taking excessively high doses; rather, I adhered to a moderate dosage based on my weight. Specifically, I took a dose of 0.4 mg per kg and, at times, increased it to 0.6 mg per kg of body weight. These doses are relatively small, and I maintained them over three months while actively fighting cancer and three additional months, post-treatment, to target any residual cancer cells that might remain. I believe, for myself, that this low dose was safe as an Ivermetin Dose for Humans.


When I fought my Cancer, Head and Neck Small squamous cell Carcinoma stage 3+, I used Fenben at 444mg a day. When people take this many do so on an empty stomach or with just a little food as they are not aware of the poor absorption rates for Fenbendazole. However, unlike the many people who use it I incorporated it in such a way that it increased bioavailability by up to 500% (see my notes at the end of my article). Because Fenben is not water soluble it MUST be taken the way I mention, or you lose it’s real potential. and in effect I may have taken a 444mg dose but with the increased bioavailability of my methods can increase that to a comparative 900 -1700mg dose, taken without an oil carrier. This is all about Absorption and how we can best use a simple method to increase the effectiveness of our Fenbendazole dose.


Case 12 - 2025: Stage 4 Adenoid Cystic Carcinoma (ACC), a type of salivary gland cancer

Published in July 2025 on Heal Navigator:

In 2017, Tim Schooley noticed a bump on his cheek.

At first, he thought it was dental-related. But after a series of referrals, a biopsy revealed a rare and slow-growing cancer: Adenoid Cystic Carcinoma (ACC), a type of salivary gland cancer.

“I was told there was a possibility that I might not be able to open my left eye again after surgery. But the operation went swimmingly.”

Tim underwent a 12-hour surgery followed by traditional radiation. The treatment successfully removed the tumor. At that point, he was cancer-free and because of the slow-growing nature of this type of cancer, doctors were hopeful it might never return…

But it did.

Scans later showed the cancer had returned this time spreading to his lungs, making it stage 4 and considered incurable.

In late 2018, scans showed that the cancer had returned this time in Tim’s lungs. Despite having six tumors, Tim still didn’t feel any symptoms.

“My oncologist said, ‘We don’t really have any great standard treatment strategy for this… but we can connect you to clinical trials.’”

Over the next few years, Tim enrolled in three clinical trials. Though it was unclear how effective they were, he believes they bought him time. Time to ask better questions. Time to explore other options.

It was during this in-between period that Tim began researching integrative strategies. An integrative oncologist handed him a study on intermittent fasting and cancer, and it clicked. He dove into books like “Tripping Over the Truth” and “Radical Remission”, learning about metabolic therapies and the terrain theory of cancer.

In early 2022, Tim sought out a repurposed drug protocol that included four medications: metformin, doxycycline, mebendazole, and atorvastatin. The overlap between metabolic disease and cancer became increasingly clear to him.

A turning point came in August 2022, when Tim underwent stereotactic radiation, a highly targeted therapy directed at the tumors in his lungs. This, combined with his ongoing metabolic protocol, laid the foundation for a remarkable outcome.

In May 2025, Tim’s scans came back: No evidence of disease in his lungs.

“There was just one little asterisk left, a tiny tumor that wasn’t growing. Now, it’s gone. It feels surreal.”

Even though his oncologist was cautious in tone, the scan report was clear. And Tim? He feels strong, empowered, and hopeful.

“I’ve worked myself into great functional shape. It’s strange I’ve had six tumors and never felt a symptom. Now I just feel healthy.”

Tim’s approach wasn’t a single fix. It was a layered, patient-driven journey anchored in metabolic healing, personal agency, and curiosity.

“I wish more people understood how much they can do for themselves. Don’t outsource your healing. Focus on your terrain. Stay curious.”

He also acknowledges the role conventional treatments played from the skilled surgical team to radiation and clinical trials. But for him, healing began when he stopped waiting for a silver bullet and started building a supportive internal environment.

“I used the money I earned from participating in clinical trials to pay for my repurposed meds. So really, my off-label scholarship was sponsored by Big Pharma,” he joked.

Today, Tim lives cancer-free, with a sense of peace, clarity, and gratitude. He knows the journey isn’t over, but for now, he’s thriving.


Case 11 - 2025: 46 year old Oklahoma man with Squamous Cell Carcinoma of Base of Tongue combines it with Proton Radiation

Dr William Makis shared on X/Twitter in July 2025:

IVERMECTIN, MEBENDAZOLE and FENBENDAZOLE Testimonial - 46 year old Oklahoma man with Squamous Cell Carcinoma of Base of Tongue combines it with Proton Radiation - they have never seen such a case! Another fascinating Cancer Testimonial! 46 year old Oklahoma man with Squamous Cell Carcinoma of Base of Tongue Patient was on: 1. Ivermectin 80mg/day 2. Mebendazole 1500mg/day 3. Fenbendazole 1000mg/day From the patient: "let me tell you my base of tongue and neck tumors have shrunk to almost nothing" "I began Proton Radiation Therapy" "My tolerance of the treatments has been something of a buzz among the Drs and caregivers. I am 21 of 35 treatments in and I can still eat and speak fine, I can even still lead the singing at one of our weekly church services! I have no pain! Minimum skin burn, like a slight sun burn. No thick saliva and no mucositis. Many of the people I have met since we started were in really bad shape by this point and several had to delay or quit treatment due to mucositis and swallowing difficulties" Despite the chemo and 1500mg Mebendazole, 1000mg Fenbendazole and 80mg Ivermectin daily, my liver numbers have been excellent"


Case 10 - 2025: 67 year old woman from Zimbabwe with Stage 4 H&N SCC of Oropharynx

Dr William Makis shared on X/Twitter in May 2025:

IVERMECTIN and MEBENDAZOLE Testimonial - 67 year old woman from Zimbabwe with Stage 4 H&N SCC of Oropharynx has excellent response after less than 3 months! I have patients from Australia to Zimbabwe. I'm going to go deep with this success story. STORY: 67 year old woman from Zimbabwe was diagnosed with H&N Squamous Cell Carcinoma of the back of the tongue in August 2022. She had chemo/rad. May 2023 to Nov.2023 declared cancer free, then found to have liver mets and was declared Stage 4. Dec.2023 to Nov.2024 was on Keytruda with good response. Nov.2024 she failed Keytruda and developed new liver and bone metastases. Reached out to me in late January 2025. In February 2025 we started: Ivermectin 1mg/kg/day Mebendazole 1000mg/day RESULTS on PET/CT after less than 3 months: Liver: “Previously visualized metastatic deposits have decreased in size, quantity and avidity” Pelvic Lymph nodes: Left paraaortic 2.1x1.3cm SUV 7.6 to 1.6x1.1cm SUV 2.1 (46% volume shrinkage) Right common iliac: 1.2x1.1cm to 0.6x0.4mm (93% volume shrinkage) Bone lesions: Manubrium SUV 11.5 to 1.7 L2 vertebral body SUV 3.5 to 2.6 Left Sacrum SUV 5.6 to 2.0 This success was a combination of: Keytruda + Carboplatin + Paclitaxel + Xgeva + Ivermectin + Mebendazole. Summary: Dec.2023 to Nov.2024: Patient on cutting edge cancer drugs developed liver and bone metastases. Feb.2025 to May 2025: Patient added Ivermectin & Mebendazole to new chemo/immuno and all metastases are shrinking and decreasing in metabolic activity. Liver, bone and lymph node metastases. LESSON: Patients often come to me when they’re at Stage 4 and progressing on the best cancer drugs modern Oncology has to offer. I am asked to clean up Modern Oncology's failures. Imagine if this patient had Ivermectin and Mebendazole at initial diagnosis. She may have never progressed to stage 4. And Big Pharma would have missed out on $100,000s in profit. This is how it works. Let’s say I can go back in time and re-do history. My Revision: Patient is diagnosed with tongue cancer in Aug.2022, is put on Chemo/Rad/ Ivermectin/Mebendazole, declared cancer free in May 2023 and stays cancer free. But where is the profit in that? Reality of Modern Oncology: Patient is diagnosed with tongue cancer in Aug.2022, is put on chemo/rad, doctors mock Ivermectin & Mebendazole, declared cancer free May 2023, becomes Stage 4 Nov.2023 with liver mets and eventually spreads to the bones, and she spends 1.5 years battling an uphill battle with Stage 4 Cancer, while big pharma rakes in $100,000s of profit on chemo and immunotherapy. This IS Modern Oncology. No one knows how bad it is until they experience it. Now imagine how low IQ someone has to be to attack me for trying to help these patients. Not only does Modern Oncology not solve the problem at initial diagnosis, but vast majority of patients see their cancer return within 1-2 years. This is where Modern Oncology really makes their money, once the patient is Stage 4 and on the endless treadmill of chemo and immunotherapy that allows Big pharma to make $100,000s until the patient dies. These are the messes I am asked to clean up. This is why I am so confident with my approach with repurposed drugs: Ivermectin, Fenbendazole, Mebendazole. Because I know how weak Modern Oncology is. How utterly abysmal their success rates. I do what they can't even dream of. From the patient: "As a matter of interest, her oncologist was blown away with her recent scan results and I told her about you and that she has been on a repurposed medicine protocol from you." "Her Oncologist was blown away".


Case 9: 62-year-old man with Head and Neck Squamous Cell Carcinoma of Tonsil (HPV+) with Lung Metastases

Dr William Makis shared on X/Twitter in May 2025:

IVERMECTIN and MEBENDAZOLE Testimonial - 62 year old man with Head and Neck Squamous Cell Carcinoma of Tonsil (HPV+) progressing with Lung Metastases - Cancer Free after 2.5 months! Sounds unbelievable, doesn't it? Stage 4 to Cancer free in such a short time... STORY: 62 year old man diagnosed with HPV Head and Neck Squamous Cell Carcinoma of Tonsil in August 2024 Treated with 5 rounds of chemo and 37 rounds of radiation in late 2024. Was told cancer had spread to lungs in Dec.2024. Reached out to me in January, 2025. We started: Ivermectin 1mg/kg/day Mebendazole 1000mg/day Oncologist put him on: Paclitaxel, Carboplatin, Pembrolizumab RESULTS (after 2.5 months): Negative NavDx Test Result CT: "Substantial response to treatment with near complete resolution of pulmonary metastatic disease. No new suspicious pulmonary nodule" From the patient: "I had a scan on Dec.30 and it showed the cancer had moved to my lungs and I had numerous nodules in both lungs" "Heard about you and reached out in January to you. As soon as I received your protocol I began following your regimen" "The good news is the scan of my lungs taken March 30 and the NavDx Blood test drawn on April 3 both reflect I am cancer free" I run the world's largest Ivermectin Cancer Clinic. Yes, the results can be this dramatic. This quickly. Here is the part that most people miss. This patient developed Stage 4 metastatic disease to the lungs after doing 5 rounds of chemo and 37 radiation treatments. In other words, this patient was at an earlier stage, went to get the best treatment modern Oncology had to offer, and ended up with Stage 4 Cancer spread shortly after. I see this all the time. Mainstream Oncology is an absolute disaster. They don't cure anything. The treatments have no long term durability. No staying power. The cancer comes back. Oncology needs a complete overhaul, but until then - we save lives with repurposed drugs: Ivermectin, Fenbendazole, Mebendazole and more...Mainstream Oncology has no idea what's coming and they're NOT ready for it....


Case 8: Head and Neck Squamous Cell Carcinoma

Dr William Makis shared on X/Twitter in March 2025:

IVERMECTIN Paste and FENBENDAZOLE Testimonial - Man with Head and Neck Squamous Cell Carcinoma gets to "No active disease".

This is a very short testimonial and sometimes success stories are like that. Short and sweet.

"My husband was diagnosed in 2021 with squamous cell cancer in his neck! He had a mass surrounding his carotid artery!

Had a needle biopsy but couldn’t be removed because of the location! I stumbled upon Joe Tippens protocol and so I got some ivermectin paste and some fenbendazole and some other things I had read about!

While he was on a round of chemotherapy and radiation therapy he started taking the 444mg fenbendazole for 4 days and ivermectin the other 3 days!

After 6 months his scans were showing no new cancer and scans every 6 months are still showing no new disease! He will stay on this protocol for the remainder of his life! If anything ever shows up we’ll just double the dose on the fenbendazole and ivermectin! No more chemo!"
I am working on many Head and Neck squamous cell carcinoma cases in my Ivermectin Cancer Clinic.

There is evidence that H&N SCC responds to Mebendazole as well as Fenbendazole, although there is more published research on H&N SCC and Mebendazole.
2017 Zhang et al - Anthelmintic mebendazole enhances cisplatin's effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC) "Our results are the first to demonstrate that MBZ may exert its anticancer activity by inhibiting proliferation while promoting differentiation of certain HNSCC cancer cells. It's conceivable the anthelmintic drug MBZ can be repurposed as a safe and effective agent used in combination with other frontline chemotherapy drugs such as cisplatin in HNSCC treatment."

2024 Zhang et al - Synergistic inhibition of proliferation and induction of apoptosis in oral tongue squamous cell carcinoma by mebendazole and paclitaxel via PI3K/AKT pathway mitigation.

"Both MBZ and paclitaxel treatments inhibited of cell proliferation and microtubule formation by reducing the PI3K/AKT pathway in CAL-27 and UM-SCC-1 cells, with the combination demonstrating synergistic effects. Our study suggests MBZ and paclitaxel as potential agents for the treatment of OTSCC."


Case 7: Salivary Gland Cancer (January 2025)

Shared on a Facebook Private Group (January 2025):

"I was diagnosed with stage 4 salivary gland cancer in April 2023. Had surgery and got most removed then did a very light chemo and 30 rounds of radiation. In August of 2023 my scans came back clean. We thought I was all done! Around March I had follow up scans done and now I have tumors on my spine, tailbone, liver, lung and pelvis. I've been on the ivermectin, fenbendazole protocol for a few months now. I'm from Kansas city and they aren't really familiar with my type of cancer...it's pretty rare. We came to MD ANDERSON Sunday to see if there is more they can do for me. I had scans done today but no results as of yet. The doctor has some ideas on what he wants to do. He was amazing, wish I could take him home with me! Anyway, that's my story in a nutshell and praying the doctors , protocol I'm doing and the grace of God, my Lord and Savior will help prolong my life cause I'm definitely not ready to go yet! Thank you for letting me share....God bless all of you".


Read More: Fenbendazole and Salivary Gland Cancer


Case 6: Tongue Cancer

Dr William Makis shared a case report on X-Twitter (Dec 2024):

IVERMECTIN & FENBENDAZOLE & Topical Ivermectin Testimonial - 70s year old US patient with Squamous Cell Carcinoma of Tongue seeing improvement - mainstream doctors coming on board! I have a 70s year old US patient with a bad case of tongue cancer (squamous cell carcinoma) Mainstream Oncology has offered to resect her tongue.  We started a high dose Ivermectin and Fenbendazole Protocol with one extra feature: topical Ivermectin cream applied twice a day. 
  • Ivermectin 1mg/kg/day 
  • Fenbendazole 888mg/day 
  • Topical Ivermectin applied to tongue lesion twice a day
One of her physicians contacted me:

"started on your protocol for a tongue neoplasm...She's noticed significant improvement in tumor size of the last few months...we would be in contact throughout treatment...thanks for all that you're doing!"


Case 5: 71 year old Canadian man with aggressive Stage 4 Oropharynx cancer (February 2025)

Dr William Makis shared on X/Twitter:

IVERMECTIN & FENBENDAZOLE Testimonial - 71 year old Canadian man with aggressive Stage 4 Oropharynx cancer sees hope and dramatic tumor shrinkage.
This patient was really not doing well on conventional radiation and chemotherapy, until he came to me... 71 year old Canadian man with aggressive Stage 4 Oropharynx cancer, progressing with lung metastases and not doing well with conventional treatments. His Canadian oncologists couldn't get the cancer under control. TREATMENT: From October 2024 we started: Ivermectin 40 to 80mg a day (he struggled but really tried to get the dose up) Fenbendazole 1000mg a day, 6 days a week A few weeks later oncologists started: Keytruda RESULTS: CT Jan.20, 2025: “On palliative systemic therapy” A bit over 3 months on Ivermectin 40-80mg and Fenbendazole 1000mg 6 times a week. Oropharynx primary tumor down from 4.0cm to 3.2cm. Right parotid mass shrunk 71% from 5.8cm to 1.7cm !! Laryngeal soft tissue mass is GONE. Cervical adenopathy shrunk 31% from 1.6cm to 1.1cm. !! 

Not bad for 3 months of repurposed drugs in combination with palliative KEYTRUDA.

This was an extremely challenging case of a Stage 4 Cancer patient who was deteriorating rapidly after radiation and conventional chemotherapy I believe we've turned things around beautifully in a way his Canadian Oncologists simply couldn't'. So far from what I'm seeing, Head and Neck cancers are responsive to Ivermectin/Fenbendazole or Ivermectin/Mebendazole, either will work!


Case 4: Advanced Epiglottis Cancer (Throat cancer)

Dr William Makis shared on X/Twitter in November 2024:

IVERMECTIN and FENBENDAZOLE - Testimonial in a patient with Advanced Epiglottis Cancer (who was offered no treatment options) Epiglottis Cancer is a type of Head and Neck Cancer that is difficult to treat surgically or otherwise. "One year ago I had the death sentence" “Surgeons offered no hope, no options” "I heard about Ivermectin...Fenbendazole" “I am alive & in gratitude to you and your....”


Case 3: Head & Neck Squamous Cell Cancer (Sep 2024)

According to Dr William Makis (X/Twitter):

IVERMECTIN & FENBEDAZOLE Head & Neck SCC Cancer testimonial 
For those who proceed with conventional chemotherapy or radiation therapy - you should know that you will get much better results combining with Ivermectin & Fenben. The results will often surprise the Oncologist!



Case 2: Oral cancer (Squamous cell carcinoma), February 2023

Condition: Oral cancer (Squamous cell carcinoma)

I was diagnosed 11/2/2022 with oral cancer on base of lower gums and on 11/5/2022, I start taking:

– Merck brand fenbendazole liquid goat dewormer 3ml a day (also equal 1/2 teaspoon) for 5 days a week.
– Doctor’s best brand: curcumin phytosome 500mg for 7 days a week.
– Now brand: ginger root extract 250mg for 7 days a week.

Went to my ENT doctor and he examined and scheduled surgery for 1/27 2023, (still taking fenben all the time) after excision of skin lesion it was sent to pathologist, the result came back – no cancer!!!

Which of the protocol components did you use? Fenbendazole, Curcumin, Other.

Other supplements used? Curcumin phytosome 500mg— ginger root extract 250mg.

Which conventional treatments did you do? Surgery.



Case 1: Throat Cancer (HPV Squamous Cell Carcinoma) (December, 2021)

I never knew that the day would surface for me to find out that I got diagnosed with cancer. My life turned upside down in seconds that day and ever since I have been doing research upon research – reading and gathering all the information I could get on the prognosis of my cancer and the treatments that are out there to help fight what is called HPV Squamous Cell Carcinoma (throat cancer).

I ended up taking fenbendazole (dose of 2,000 mg) after a consultation with a holistic doctor who examined it with added supplements to the fenben protocol the doctor has put me on.

My tumor shrunk 1 cm in one month from using fenbendazole which was also before I had to start with several radiation treatments and doses of cisplatin chemotherapy to come. As the radiation and chemo journey started for me, I could not tolerate what it was doing to my body any more and decided to stop with it completely and just commit to my health and take fenbendazole along with the individualized supplements suggested for me to use. This took not just a lot of commitment but a lot of faith in the matter!

A few months past and near to the end of 2021, I received my follow up PET scan with the greatest news ever – I am completely cancer free – and still today! With results of significant response to the treatment.

Without saying a word to anyone out there, I pursued this journey and with experience I can say that fenbendazole can definitely cure cancer!


11. Kidney Cancer Success Stories (13 cases)

Case 13 - 2025: 68 year old North Carolina man with Stage 4 Renal Cell Clear Cell Carcinoma*

*Note: Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer, where cancer cells appear clear or pale under a microscope and originate from the kidney's filtering tubules.

Dr. William Makis shared on X.com in September 2025:

IVERMECTIN and MEBENDAZOLE Testimonial - 68 year old North Carolina man with Stage 4 Renal Cell Clear Cell Carcinoma - Cancer Free after 9 months! Oncologists have very poor success record with Kidney cancers. I think we do much better! This is one of my early successes. 68 year old North Carolina man with Stage 4 Renal Cell Clear Cell Carcinoma We got to work back in November 2024
  • Ivermectin
  • Mebendazole
9 months later: "CT Scan reveals suspected lung metastases faded away". Oncologist confirms that I am cured of kidney cancer" "THANK YOU so much for all that you have done for me and others. Your one of the very few honest doctors out there that cares".


Case 12 - 2025: 42 year old woman with Stage 4 Kidney Cancer to lungs, liver and shoulder

Dr. William Makis shared on X.com in August 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 42 year old woman with Stage 4 Kidney Cancer to lungs, liver and shoulder, is CANCER FREE after one year! STORY: 42 year old woman with Stage 4 Kidney Cancer to lungs, liver and shoulder Started Ivermectin and Fenbendazole Reports back after 1 year: "my scan today showed NED (No Evidence of Disease)." "I cannot thank you enough for what you are doing for people who are being handed a death sentence. You have given so many of us hope! Bless you"



Case 11 - 2025: 74 year old North Carolina woman with new Renal Cell Carcinoma (papillary)

Dr. William Makis shared on X (Twitter) in July 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 74 year old North Carolina woman with new Renal Cell Carcinoma (papillary) has tumor shrinkage after 4 months Oncologists have no answers for Kidney Cancer but there is hope! 74 year old North Carolina woman with new Renal Cell Carcinoma (papillary) Regimen (started Feb.16, 2025): Ivermectin 1mg/kg/day Fenbendazole 1000mg/day Results after 4 months Left kidney cancer shrunk 1.4x1.7cm to 0.9x1.3cm = 68.4% tumor volume shrinkage It’s important to note that neither Radiologists, nor Oncologists do any calculations of tumor volume reduction. This radiologist called a 68% tumor volume reduction “mildly decreased”.


Case 10: 63 year old Florida man with Stage 4 Clear cell renal cell carcinoma (ccRCC)* metastatic to chest

*Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer, making up about 80% of all kidney cancer cases.

Dr. William Makis shared on X (Twitter) in April 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 63 year old Florida man with Stage 4 Renal Cell Clear Cell Cancer metastatic to chest becomes "CANCER FREE" after 3 months! Renal Cancer is a tough one...or...is it? 62 year old man with history of Stage 3 locally advanced Renal Clear Cell Carcinoma had a 3 cm tumor recurrence in the hilum. In early August 2024, this was one of my first patients. We started:
  • Ivermectin 1mg/kg/day increasing to 2mg/kg/day
  • Fenbendazole 1000mg/day
July 2024 PET/CT showed: 3cm hilar metastasis Aug 2024 (early): Ivermectin + Fenbendazole Oncologist: immunotherapy Nov.18, 2024 PET/CT: Cancer Free Apr.5, 2024 PET/CT: Cancer Free April 7 patient wrote me: "I promised I would keep you in the loop on my follow-up PET/CT scan. No evidence of cancer! Again, I want to thank you for helping me. " "Most people I talk to, especially those that have cancer or their loved ones have cancer, think I am nuts with the protocol I take but the results speak for themselves!" "I will keep spreading the word and praying for you and your family" PET/CT April 5, 2025: "No evidence of recurrent or residual renal cell cancer". "The most recent PET/CT showed a complete response" "My Oncologist is thrilled". I bet he is!
Because he sure as heck didn't do this. My Take... Quick. Easy. Cancer Free. Look, it honestly doesn't have to be complicated. The good news here is that there wasn't much overall tumor burden to deal with. One 3cm lesion. Patient jumped on this quickly before it spread further and he also knew that the Oncologist, having failed once, probably wasn't going to fix this. Remember, he was cancer free, on top of the line treatment that modern Oncology can offer in the United States (immunotherapy) and he STILL developed a 3cm recurrent cancer! I don't know how he found me, but he did. It was Day 3 of my Cancer Clinic. I'm now in the 8th month.


Case 9: 2 year old girl with Wilm's Tumor (Kidney Cancer) metastatic to the lungs

Dr. William Makis shared on X (Twitter) in April 2025:

IVERMECTIN and MEBENDAZOLE Testimonial - 2 year old girl in India with Wilm's Tumor (Kidney Cancer) metastatic to the lungs is improving. My youngest cancer patient! Let me tell you about my youngest cancer patient. 2 year old girl in Mumbai, India, has a recurrent Wilm's Tumor (pediatric kidney tumor) metastatic to the lungs. She had an operation to remove the tumor in Sep.2024 But it came back in March 2025: "We have today found that she has relapsed in spite of the ongoing chemotherapy". The family reached out to me. We started Ivermectin and Mebendazole. One month later: "Kindly find the latest CT report of the lungs (refractory Wilms tumor metastasis) along with the one from March. This shows a significant improvement in the last 30 days...we have used your protocol" After starting Ivermectin and Mebendazole, she is improving and the lung tumors are shrinking. Largest lung tumor has shrunk from 7.2x6.0cm to 4.6x5.3cm. Radiologist: "Interval regression in size...Imaging features suggest partial response to therapy" These are very difficult cases and I always hesitate to take on pediatric patients.

But if I don’t help, who will? Pediatric Oncologists don't put their neck on the line any more than adult Oncologists. You don't upset big pharma, or your Oncology career is over, patient be damned. There is research to back the use of Ivermectin and Mebendazole in children. Ivermectin: 
2020 de Castro et al - Continuous high-dose ivermectin appears to be safe in patients with acute myelogenous leukemia and could inform clinical repurposing for COVID-19 infection - three children with leukemia were successfully treated with Ivermectin. Mebendazole: NCT02644291 - Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors This is a safety (Phase 1) trial using mebendazole for recurrent pediatric brain cancers that include medulloblastoma and high grade glioma, that are no longer responding to standard therapies We have shown efficacy in preclinical laboratory models of high grade glioma and medulloblastoma. Mebendazole therapy demonstrated safety in a phase I clinical trial for adults with high grade gliomas such as glioblastoma The patients for this experimental trial are those between the age of 1 to 21 with the diagnosis of medulloblastoma, or high grade glioma, where the tumor has resumed growth or continued to grow despite standard medical therapy. Mebendazole is provided at no cost in the form of a chewable 500 mg tablets, recommended to be taken three times daily with meals or food. In one month we achieved with Ivermectin and Mebendazole what Oncologists couldn't achieve - the tumors are shrinking. I don't share this case for any reason other than to give hope to parents out there struggling with such cases. This case is in God’s hands. I pray for success.


Case 8: 68 yr old Male with Stage 4 Clear Cell Renal Cell Carcinoma - shrinking lung metastases by 60-70%! 

Dr. William Makis shared on X (Twitter) in March 2025:

Do you think Renal Cell Carcinoma can be beaten? Most doctors will tell you it can't. Well, they're wrong. Of course, your local friendly mRNA Vaccinated Oncologist has no chance to even contemplate this. Story: 68 year old man with Stage 4 Clear Cell Renal Cell Carcinoma and lung metastases reached out to my Ivermectin Cancer Clinic.
  Did a 3 month protocol of :
  • Ivermectin 2mg/kg/day
  • Fenbendazole 888mg/day
  • CBD Oil 25mg/day
  • Melatonin 120mg/day
RESULTS: Largest lung metastasis shrunk from 1.3x0.7cm to 1.2x0.3cm. According to Grok, that’s a reduction of 60-70% tumor volume. Another lung nodule shrunk 0.7cm to 0.6cm, a reduction of 37% tumor volume. No chemo. No radiation. No immunotherapy.


Case 1,2 and 3: Three patients with different primary kidney related tumors demonstrated complete response (CR) after receiving FenBendaZole (FBZ) therapy.

Despite multiple anecdotal stories and news outlet reports for its efficacy in treating metastatic cancer, the clinical literature behind utilizing FBZ (fenbendazole) as a potential anti-neoplastic agent remains nonexistent. Existing scientific studies have primarily studied its mechanism of action through the use of animal models. In a study published in Clin Oncol Case Rep (2020), researchers from Stanford University describe three cases where patients achieved complete responses, including two who experienced progression after multiple lines of therapy, when FBZ was used alone or in combination with standard therapies.

In summary, three patients with different primary genitourinary tumors who demonstrated complete response after receiving FBZ therapy. This raises the question of how effective FBZ can be as an anti-oncogenic agent and merits further investigation. 

According to the authors:

Prior studies have demonstrated cancer response to immune checkpoint inhibitors such as nivolumab as a third-line agent in mRCC (metastatic renal cell carcinoma). The duration of therapy was often much longer requiring a median therapy duration of 6 months with 24% overall response rate in third-line treatment. It is possible that our first patient with mRCC would have achieved a significant response to nivolumab alone without FBZ. However, given the complete radiologic response on only 1 month of immune checkpoint inhibitor therapy, it also seems likely that FBZ played a notable role in inducing remission. This is supported by the fact that our patient has remained in extended remission while only on FBZ for nearly a year without further administration of immune checkpoint inhibitor therapy.

Case 4: July, 2022


Husband diagnosed 7/19/21

Stage 4 Metastatic Clear Cell Renal Carcinoma (aka Kidney cancer).

Surgery 8/2/21 left radical nephrectomy with complications and have colostomy

9/2/21 Start Opdivo

10/2021 colostomy reversal

11/2021 land in ER with sepsis (unknown origin) and have surgery

11/2021 Start Yervoy in addition to Opdivo (and FenBen)

11/2021 (just before Thanksgiving), doctor said ”let’s see if you can make it 5 weeks” when husband asked about prognosis

12/21 Travel to NYC to spend what my husband believes is his last Christmas

1/3/21 ER visit due to lack of lucidity

1/22 Start Cabo (have been off FenBen because of all the hospital visits)

2/4/22 see medical consultant – start FenBen again

5/22 – Cancer is shrinking some totally gone – off nearly all pain meds. Doctor says he’s never seen this much progress in such little time.

6/22 – Cancer is still shrinking – off almost every pain med (1 10MG Oxy a day)

7/22 – Cancer still shrinking!! PTL

Not doing anything crazy

Case 5: November, 2021


In the beginning of 2021 I was diagnosed with stage three kidney cancer followed by stomach cancer a few months after.

I did not want to go for any radiation or chemo knowing the adverse effects it will have on my body. I jumped onto a fenbendazole course immediately which I followed for a good 6 months and got the incredible news that I am completely cancer free!

Case 6: December, 2021

In 2016 I was diagnosed with stage 4 cancer in my kidney and abdomen alongside a secondary diagnosis of follicular lymphoma. The Oncologist predicted that if I am lucky I will have 6 months left to spare.

I declined any medical help that came my way and decided with dedication and faith to take the natural path to healing from the very beginning of my cancer journey.

It has been a challenging journey for me the last year and I thought I might not make it at one point. But, then, everything started to change and my symptoms were fading slowly but surely from using various methods and eventually ended up taking fenbendazole and following the protocol religiously. I started off on a dose of 150mg and kept on increasing it from there over a period of four months. I showed symptoms when I hit the 600mg dosage and was very concerned that it might not be the best approach and even though I kept on increasing the dose over a reasonable amount of time and took a break off of it for a couple of days before I would continue on it again.

Over the last month the swelling in my face seems to have decreased and I don’t experience anymore pain in my eye, and the lymph nodes were busy disappearing up to the point of not being visible anymore. My persistence and belief in the protocol paid off, this is the least I can say!

I still have a long journey to walk, but I am more motivated than ever and I attribute all the success to the use of this protocol and encourage everyone to give it a go! Do not lose hope.


Case 7: Renal Cell Carcinoma (Stage 4) - July 2024

Source: William Makis, MD (X.com)

See also Bladder (Urinary) Cancer success stories (above)

Related: First-Line Therapy For Advanced Non–Clear Cell Renal Cell Carcinoma: A Systematic Review and Meta-Analysis (JAMA Oncology 2025)

13. Liver Cancer Success Stories: Fenbendazole (3 cases)

Case No. 3: 44 year old Australian Man with Hepatocellular Carcinoma (HCC)

Dr. William Makis shared on X (Twitter) in July 2025:

Ivermectin and Mebendazole Testimonial - 44 year old Australian Man with Hepatocellular Carcinoma (HCC) reports success after 3 months A success story all the way from Australia! I'm actually helping many cancer patients in Communist Australia, where it's much harder to get Ivermectin and Fenbendazole but where there's a will... 44 year old Australian Man with Hepatocellular Carcinoma (HCC) Late Feb 2025 we started:
  • Ivermectin 1mg/kg/day
  • Mebendazole 1000mg/day
  • Melatonin 300mg/day
Results after 3 months: Tumor markers decreased by 25% Liver lesion decreased from 37mm to 30mm = 46% tumor volume shrinkage CT: "Significant decreased volume and extent of enhancement of the hepatic lesions from prior" From patient: "Looks like I am going in the right direction. Thanks a lot for your help"

HCC is extremely difficult to treat and Oncologists have no answer for it.


Case No. 2: September, 2021

I was given less than two years to live in 2020 when I was diagnosed with stage 4 (metastatic) HCC (HepatoCellular Carcinoma) liver cancer. I received radiation directly onto the tumors and went for immunotherapy which did not bring any improvement to my state I was in. My wife and family did research and came across the fenbendazole protocol. I had nothing left to lose, so I decided to give it a try.

Case No. 1: September, 2021

In 2021 the doctor discovered a tumor growth at the end part of my colon. The test results declared a colon tumor with some small lesions on my liver back then. This was a lot to take in considering the thought of having to go through surgery and a colostomy. I have been a super active person for almost all of my life, taking my vitamins on a daily basis as I start my day – I never thought that something like this could ever happen to me.

After I made peace with what was happening inside my body, I gathered myself and started seeking for the best possible advice/guidance out there on any alternative approach other than putting my body through all this stress. I managed to start a protocol on: 1mg FECO, RSO oil which I used on the daily, and supplements at night along with some juicing which includes soursop & green tea, 20000mg Vit D, 5000mg Vit C & Vit K, 800mg grape seed extract, 2100mg ashwagandha, 1950mg curcumin with ginger & black pepper, sea cucumber extract, and 2000mg Fenbendazole on a daily basis (½ in the morning; ½ at before bed).

I never told my doctors about this and continued with treatment alongside the use of this protocol. A few months has passed since I started this journey and I received my results again later that year, showing no presence of any tumor. It completely vanished into thin air! After only four chemo treatments the doctor could not comprehend how the cancer just managed to disappear like that, and so quickly too – considering the time period for chemo to work to be proven to take much longer before it actually starts working.

See Bile Duct Cancer (Cholangiocarcinoma) above.

14. Lung Cancer Success Stories (15 Cases)

Case 15: 68 year old man in India was diagnosed with Stage 4 Lung Cancer with metastases in the lymph nodes, bones, liver, spleen and brain

Dr William Makis shared on X/Twitter in May 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 68 year old man in India with Stage 4 Lung Cancer baffles doctors as all tumors shrink by up to 94% after 2 months!!
This success story from India is dedicated to everyone who attacked me this week.
  If you think I'm only helping cancer patients in North America, you'd be wrong... 68 year old man in India was diagnosed with Stage 4 Lung Cancer with metastases in the lymph nodes, bones, liver, spleen and brain. His family reached out to my Ivermectin Cancer Clinic. We started: 
  • Ivermectin 1mg/kg/day 
  • Fenbendazole 1000mg/day
Results after 2 months: "His doctor did not say any word after seeing the report. He just mentioned report is OK, we will complete the remaining chemo cycle. Inside I knew he was also shocked to see the report.

"I can not thank you enough" PET/CT showed shrinkage and decreased metabolism of EVERY metastatic tumor including in the brain.

Example: Right Lung Primary Malignancy: 
3.2x2.7x3.5cm shrunk to 1.6x1.0x1.2cm (94% tumor volume shrinkage) 
SUV 14.5 to SUV 3.1

"Hypermetabolic mediastinal lymph nodes, spleen lesion and brain lesion and liver lesion with low significant metabolism. Interval significant reduction in metabolic activity and size"


Case 14: 45-year-old UK woman with Stage 4 Non-Small Cell Lung Cancer with lymph node, liver and adrenal metastases

Dr William Makis shared on X/Twitter in April 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 45 year old UK woman with Stage 4 Non-Small Cell Lung Cancer with lymph node, liver and adrenal metastases, has 75% of disease gone after 4 months! Ready for a nice Stage 4 Lung Cancer story? 45 year old UK woman with Stage 4 NSCLC Lung Cancer with lymph node, liver, and adrenal metastases. In early September 2024 we started:
  • Ivermectin 1 to 2 mg/kg/day (eventually built up to 96mg Ivermectin a day, or 1.5mg/kg)
  • Fenbendazole 444mg a day
  • CBD Oil 25mg a day
  • Melatonin 120mg a day
Oncologist started Osimertinib (Tagrisso)

RESULTS (January 2025 PET/CT):
  • Adrenal metastasis shrunk from 6cm to 3.6cm
  • Lymph node metastases resolved
  • Liver metastases resolved
  • Oncologist estimated 75% of tumor burden had resolved.
The patient had some transient visual side effects with Ivermectin which are typical in the beginning but they went away.

"Liver completely cleared up" 
"Lymph lump in neck completely gone"


Case 13: IVERMECTIN and FENBENDAZOLE Testimonial - Stage 4 Lung Cancer patient in India with metastases to brain, liver and bones, sees dramatic recovery including "complete resolution" of liver & bone mets!  (Jan 2025 update)

Case testimonial from Dr William Makis (X/Twitter):

"IVERMECTIN and FENBENDAZOLE Testimonial - Stage 4 Lung Cancer patient in India with metastases to brain, liver and bones, sees dramatic recovery including "complete resolution" of liver & bone mets! An International story you're going to love! Adarsh contacted me in early September 2024 about his dying father in India who had Stage 4 Lung Cancer with metastases everywhere including brain, liver, bones. 
"doctors has given some months to live".
So I suggested an Ivermectin/Fenbendazole Protocol - something simple, yet powerful: Ivermectin 1.5mg/kg/day 
Fenbendazole 444mg/day (I suggested up to 888mg)

RESULTS:

PET Scan of 27 November, 2024: - complete metabolic resolution of liver and bone metastases (!) - decrease in size and number of mediastinal lymph nodes - decrease in size of brain metastases (!) - decrease in lung lesion. There are people who claim Ivermectin and Fenbendazole don't cross the Blood Brain Barrier. Well, they're wrong!"
 





Case 12:

source: https://substack.com/home/post/p-155091883


Case 10: IVERMECTIN and FENBENDAZOLE Testimonial - 40s year old California Man with Stage 4 Lung Cancer (Jan 2025 update)

Case testimonial from Dr William Makis (X/Twitter):

"IVERMECTIN and FENBENDAZOLE Testimonial - 40s year old California Man with Stage 4 Lung Cancer (post three Pfizer COVID-19 Vaccines, Turbo Cancer?) sees dramatic improvement in 3 months! Another wonderful story for you:

40s year old California man (who had three Pfizer COVID-19 mRNA Vaccines), was coughing for months, and was diagnosed with an unexpected Stage 4 Lung Cancer (NSCLC) metastatic to numerous lymph nodes and pleura, with a pleural effusion. We started an aggressive protocol: 
  • Ivermectin 1mg/kg/day increasing slowly to 2mg/kg/day (high dose!)
  • Fenbendazole 888mg/day
  • Oncologist also started Tagrisso (Osimertinib)
3 Months Later: Primary lung tumor reduced in size from 3cm to 2cm. Pleural effusion resolved completely (!) Gained 15 pounds of weight from his lowest before he started the protocol. These are very significant improvements!"







Case 9: November 2024 - Ivermectin and Fenbendazole for stage 4 NSCLC Lung Cancer

Case testimonial from Dr William Makis (X/Twitter):

IVERMECTIN and FENBENDAZOLE Testimonial - 40s year old woman with Stage 4 NSCLC (Non Small Cell Lung Cancer) - dramatic improvement after 3 months! 

40s year old Stage 4 Lung Cancer Patient in the UK In August 2024, we started Ivermectin 1mg/kg/day and Fenbendazole 444mg/day 6 days on 1 day off 

There were some transient visual effects from Ivermectin to overcome in the first few weeks (see messages) But they went away after a few days! 

And less need for strong pain medications! 3 month Follow-up Report: 

“Cancer is stable and all lesions / tumours have shrunk” 
“biggest shrink of all was the one above adrenal gland which has gone from 6cm to 3.6cm!” 
“spots on the left lung and liver were so small they were too small to measure” 

My Take… It is wonderful to see results like this after only 3 months! Sometimes there are some minor growing pains in the beginning - some transient side effects to overcome (like the visual side effects of ivermectin), but once you overcome them, it’s smooth sailing! In this case they lasted about 10 days and then they were gone. 

And yes, we did push to get to Ivermectin 2mg/kg/day (substantial dose) and Fenbendazole 888mg/day (moderate dose). Can you imagine a Stage 4 Lung 6cm adrenal metastasis shrinking to 3.6cm and all other lesions shrinking, some disappearing or becoming too small to measure? In just 3 months? Not bad for horse medicine!






Case 8: November 2024

Case sharing by Gerard Donald (X/Twitter):

I'm not ready to post exact details, but my wife's Stage 4 lung cancer is seemingly going away. Main tumor has gone from 6.4 to 2.6. Lymph spits all but gone. Lower lung spot gone. She has been on a targeted gene therapy drug and is using fenbendazole, curcumin, and Vitamin E.



Case 7: October 2024 - Ivermectin and Fenbendazole for stage 4 Lung Cancer

Case testimonial from Dr William Makis (X/Twitter):

One of my cancer patients is a woman in her 70s with Stage 4 Lung Cancer with multiple liver metastases. “Less than 7 weeks after initiating the protocol” 

Primary Lung lesion LLL 2.9cm to 2.1cm (28% decrease) 

Liver at porta hepatis 5.3cm to 1.6cm (70% decrease) 

Right hepatic lobe inferiorly, 2.4cm to 1.0cm (58% decrease) 

Right hepatic lobe, 2.1cm to 0.8cm (62% decrease) 

“Overall, hepatic metastases appear markedly decreased in size when compared to the previous CT”
"I wholly believe, as does my wife, that the protocol is doing the heavy lifting".



Case 6: September, 2023


Condition: Stage 2 Adenocarcinoma in his upper right lung lobe

In July of 2018, my husband received his first cancer diagnosis. Stage 2 Adenocarcinoma in his upper right lung lobe. Mutations tested. Lobe was removed

July 23, 2018, and he was put on active surveillance, no treatment.

On 11/14/2018, he received his second diagnosis, prostate cancer, adenocarcinoma with metastasis, stage 4, and Gleason score 9. Prostate was removed,followed by 7 weeks of radiation, and put on ADT therapy (Lupron and Xtandi), no chemo. Mutations tested, not favorable, and very aggressive. He is a rare case where cancer didn’t show in blood or any scans. To this day, it still doesn’t. We can only monitor by symptoms.

He started to progress in symptoms in June of 2022. August of 2022, diagnosed with a 2nd lung cancer, stage 4 adenocarcinoma. Mutation testing repeated, this time, it showed similar mutations as 1st lung cancer, but also some slightly different ones that led them to believe it was a different cancer.

He began treatment on 01/09/2023. We were not given any hope, and they said mutations were not in his favor and that treatment was highly unlikely to do anything, but they offered it anyways saying it would buy him time. They made it very clear he did not have the mutations they were hoping to see, they were hoping it was a mutation that responds favorably to treatment,and he didnt have those.

It didn’t make sense, in 1 sentence they stated it wasn’t likely to work, but yet it could buy him time?? It is his journey, and he decided to try. 2 chemo drugs, and I immunotherapy for 4 treatments spaced 3 weeks apart. Then they dropped 1 chemo and said he would stay on double treatment for up to 2 years, then they would drop to just immunotherapy. He stayed on double for 7 treatments. But his body was worn out. They decided 1 more treatment, and if scans looked good, they would drop the other chemo. But he got sick just before the last double treatment was supposed to happen. It has delayed his scan as well. But it is a viral thing, not cancer related, as far as we know.

Let’s get to the good stuff though… People started sending me messages, LOTS of people, asking me if I’d heard of the Fenben Protocol. I started getting these messages in August of 2022, right after his biopsy confirmed a new occurrence. To be honest, I ignored the messages until I got 2 in 1 day in November. I decided ok, I’m going to check this out. I joined the group on December 16th, 2022 and I started tearing into the files. And I started researching, and research led me to a medical sight that leaned very favorably in Fenbens direction. We discussed as to whether to bring it up to oncology, but they had made it clear in the beginning that if we choose to do natural, they would not treat him, so we kept our mouths shut.

He started the protocol at the end of February. His scans on 12/22 and 02/23 showed new masses had grown since the scan in July of 22. But by the next scan on 04/06/2023 many of the masses were still present, but stopped growing. But the masses in his pleura (which is what deemed him terminal) were almost gone! Let me note right here, that by this time, his prostate symptom progression stopped, and then the symptoms resolved.

Next scan on 05/30/2023, pleura masses are now unremarkable, and the other scattered masses still haven’t grown any.

Next scan on 07/30/2023, pleura isn’t even discussed, no remarks! Dr says they can’t see anything there at all! And the other masses remain unchanged, no growth! Whether we simply bought him time, or he’s healing, we will take it! But our hope is restored. He’s not in pain and he’s still his ornery self. And we remain grateful to the community for the knowledge and support.

Case 5: July, 2022

I have stage 4 Adenocarcinoma of the lungs…doctor told me it’s not curable. I’m 44 with two teenagers so I don’t want to hear that kind of news. Anyway, I was diagnosed in December and by January I received chemotherapy. A friend told me about Fenbendazole and I started it immediately. I am now on chemotherapy, immunotherapy, and Fenbendazole. After 4 treatments…I had a PET Scan….the scan was remarkable. Many subcentimeters nodules resolved, the two large masses are shrinking, no enlarged lymph nodes in the hilar and mediastinal region. No new growth! I’m hoping this is a good sign.

*Using Fenbendazole 220mg day and night, chemo taxol/Carbo, and Keytruda since January.

Plan to start Vitamin E, Milk thistle for liver, and Turmeric/Curcumin this week.



Case 4: July, 2022

They gave my husband 18 months to live in 2019, from having SCLC with no primary tumor. Mets everywhere. He has been doing Joe Tippens protocol before he even started chemo. Chemo didn’t work and he is now on Opdivo infusions once a month. We found out he had cancer from 3 fractures on his vertebrae. Went to his brain and that’s all gone also. Thank you Joe!! Praise the dear Lord!!

DATE OF EXAM: May 5 2022 10:17AM

AKP 0063 – NM PET/CT SKULL-THIGH SUBQ / ACCESSION # 130564079

PROCEDURE REASON: Malignant neoplasm of unspecified part of unspecified

bronchus or lung (HCC)

Case 3: March, 2022

In 2020, I was diagnosed with stage 4 lung carcinoma. The Oncologist found a big tumor growing on my left lung along with a massive tumor inside my chest cavity so big that it started constricting my heart arteries.

They started me with radiation right away followed by weeks of intensive chemotherapy, and I got so sick that they had to lower the doses and frequency to half of what they originally had me on.

Case 2: November, 2021

About three months ago my wife was diagnosed with metastatic cancer on her lungs and gave her a 3 months prognosis. She had five aggressively growing nodules.

A friend reached out to me about the fenbendazole protocol that she was following at the time. Today my wife came back from a visit to the Oncologist with test results showing a major improvement on the growths – only two small nodules were found! This is truly a miracle and a blessing!

Case 1: Small Cell Lung Cancer (SCLC) with Joe Tippens Cancer Protocol (2017)

Joe Tippens founded the fenbendazole protocol after he was told a story about a scientist at Merck Animal Health that had been performing cancer research on mice. The research included injecting different types of cancers into different mice body parts. The scientists discovered, through trial and error, a product in their canine product line, fenbendazole, that was batting 1.000 in killing these different cancers in the mice. The scientist was later diagnosed with stage 4 brain cancer and was given a grim prognosis of only three months to live. She decided to try the fenbendazole, and after six weeks, showed a clean scan.

Joe Tippens had been initially diagnosed with small cell lung cancer. The cancer later spread to his neck, right lung, stomach, liver, bladder, pancreas and tail bone. Like the scientist from Merk Animal Hospital, Joe was told he only had three months to live. In 2017, after hearing the story of the scientist who treated her cancer with a canine drug, Joe decided he was going to do the same. However, in addition to taking the fenbendazole, Joe added his own ingredients to the regimen (curcumin, CBD oil, and vitamin E), thus creating the Joe Tippens Cancer Protocol.



14. Leukemia (Acute Myelogenous Leukemia (AML) and Chronic Lymphocytic Leukemia (CLL))

2 Case testimonials from Dr William Makis (X/Twitter):

IVERMECTIN and FENBENDAZOLE Testimonial - Two blood Cancer Cases: Acute Myelogenous Leukemia (AML) patient becomes "cancer free" and Chronic Lymphocytic Leukemia (CLL) patient improves 1st time in 2 years! Case 1: AML Patient diagnosed in October 2024 Immediately started 72mg Ivermectin and 1000mg Fenbendazole 3 days on 4 days off Also did 2 rounds of chemo in November and December, and in December added oral chemo pill Venclexta Results after 2 months of Ivermectin & Fenbendazole: "His bone marrow biopsy from December 24th came back clear! His blood work is looking good." "We are so thankful for men like you that are willing to do the right thing in the face of great persecution" ====== Case 2: 63M CLL patient with a high WBC count in Sep.2022, on “watch and see” I didn’t go aggressive here, started: 70mg Ivermectin and 500mg Mebendazole: Results: WBC 16.1 (Oct.2) → 15.6 (Dec.6) —> 14.1 (Jan.15) Lymphocytes 13.0 (Oct.2) —> 12.5 (Dec.6) —> 11.3 (Jan.15) On Dec.11 I made a few minor adjustments: increased from 500mg to 1000mg/day Mebendazole and added 1000mg/day Lactoferrin. After 2 years of being abnormal, the WBC and Lymphocytes are trending towards normal range (almost there)! "It is definitely trending down since beginning the protocol" Right now, there is only one peer reviewed publication that has documented the use of Ivermectin in Human Cancer Patients. Can you guess what the Cancer is? Leukemia. And it's behind a paywall. 2020 de Castro: "Continuous high-dose Ivermectin appears to be safe in patients with acute myelogenous leukemia and could inform clinical repurposing for COVID-19 infection"






15. Lymphoma Success Stories (10 cases)

Case 10 - 2025: 46 year old Canadian man with Stage II Hodgkin Lymphoma

Ivermectin and Fenbendazole Testimonial - 46 yo Canadian man with Stage II Hodgkin Lymphoma (9x7x11cm mediastinal mass) goes into remission after 3 months with Ivermectin, Fenbendazole and Radiation! An incredible story of lymphoma - from a massive 11cm mediastinal tumor to "Cancer Free". 46 year old Canadian man with Stage II Hodgkin Lymphoma (9x7x11cm mediastinal mass) From Dec.2024 to March 2025, for 3 months, he took:
  • Ivermectin 1mg/kg/day (increasing to 2mg/kg/day)
  • Fenbendazole 1332mg/day
  • CBD Oil 100mg/day
  • Melatonin 300mg/day
Results: The anterior mediastinal mass shrunk from 11cm to 2.9cm with no FDG uptake (could just be residual scar at this point) The Oncologist informed the patient that he is now in remission!

Source: https://x.com/MakisMD/status/1937984358432051382 (June 2025)


Case 9 - 2020: 83-year-old male with Diffuse Large B-Cell Lymphoma

An 83-year-old male, presented with heartburn, trouble swallowing, and fatigue. An Esophagogastroduodenoscopy (EGD) revealed superficial duodenal ulcer which was biopsied and revealed DLBCL, GCB subtype. Fluorescence in Situ Hybridization (FISH) was negative for c-MYC, BCL2 and BCL6. A Positron Emission Tomography/Computed Tomography (PET/CT) scan revealed hyper-metabolic activity in the distal gastric antrum, proximal duodenum, peri-aortic lymph node, and pulmonary nodules. Patient was staged as stage Iva, and was offered chemotherapy, but he declined treatment due to side effect profile.

He started to take fenbendazole 1g daily based on self-research (used to take between 1-6 tabs daily based on his symptoms). After 6 months, he cut down fenbendazole to 1-3 tabs daily due to peripheral neuropathy. He presented to his primary care physician who obtained a repeated CT scan which revealed smaller mediastinal lymph nodes. After 2 months, he decided to follow with oncology, so he had repeated PET/CT scan which revealed improved lymphadenopathy from prior scans.

In the next 3 months, he continued to taper down fenbendazole and reached 3 pills weekly. A repeated PET/CT scan revealed interval improvement in his disease with no new lesion seen.

Source: Annals of Hematology & Oncology 2020


Case 8 - 2025: 65-yr-old male with Early Lymphoma

Mike Ridgway of Tennessee treated his early lymphoma with two shoeboxes of medications from India. Within eleven months, his three PET scans went from ominous to better to normal.

A retired software programmer, Ridgway took long-established, off-patent drugs that are surely not on a typical oncologist’s radar: ivermectin, fenbendazole (a veterinary drug), and colchicine. They cost $400 for six months of treatment. Standard pharmaceuticals for early lymphoma, by contrast, cost an average $12,396 a year in the United States.

Ridgway, who is sixty-five years old, represents a small share of cancer patients who choose alternative care in part because they mistrust profit-driven oncology and dislike the chemo drawbacks. The drugs they take—under the supervision of a physician and sometimes with traditional therapies—are supported by considerable laboratory and animal studies and some human research.

For cases in which the outcomes are known, he prescribed his ivermectin-fenbendazole cocktail to sixteen patients, who almost all had been given one to four weeks to live. Thirteen survived from six to ten months before dying, he said. One near-death pancreatic patient, who had exhausted the gamut of chemotherapy, lasted more than a year.

“It’s difficult to reverse the (chemotherapy) damage,” DeMello said, who has six other cases in various treatment stages.

In two of his first sixteen cases, however, patients bypassed traditional care and went first to DeMello. Rohini Hughes, a fity-three-year-old advanced colon cancer patient, is alive though suffering, twenty months after her remaining time was measured in days. Mike Ridgway, whose cancer was caught early, was given a clean bill of health nearly a year after the disease emerged.

“I cannot overstate how blessed my wife and I feel,” Ridgway said.

Ridgway became friends with DeMello through Facebook, where they shared like-minded views of the flaws of official pandemic policies.

Ridgway’s first inkling that he was facing a serious health problem was in February 2024 after suffering abdominal pain and enlarged lymph nodes. “This PET scan will find cancer anywhere in your body,” the technician told a startled Ridgway.

Indeed, the scan showed “two nodes in the left upper abdominal mesentery that are markedly hypermetabolic, and lymphoma is a primary consideration.”

An oncologist ordered a biopsy, telling Ridgway unequivocally, “The tissue is the issue.”

He turned to DeMello, who “was very, very emphatic against it,” Ridgway said.

“I am convinced that there is no useful role of biopsy (and risk of spreading cancer) especially when a non-invasive test like PET scan can confirm the presence of malignancy,” DeMello explained. “Two huge lymphomas” on Ridgway’s scan were diagnostic for him.

“Unless he had a major infection, with symptoms of fever, high WBC counts, high neutrophil counts,” he said, “the only diagnosis for such huge tumors in the abdomen is malignancy’.”

After that, Ridgway opted to follow the advice of a doctor he respected half a world away.

“It’s nothing short of a miracle that the two of us were in communication when I received my diagnosis for cancer,” he told me.

Source: Ivermectin and Fenbendazole May Just Quell Cancer - Mary Beth Pfeiffer


Case 7: 49 year old Georgia man with Stage 4 Diffuse Large B-Cell Lymphoma in mesentery

Dr William Makis shared on X/Twitter in May 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 49 year old Georgia man with Stage 4 Diffuse Large B-Cell Lymphoma in mesentery has almost complete response after 3 months and NO CHEMO! A lymphoma case. Almost complete response. The most shocking part: NO CHEMO! STORY: 49 year old Georgia man presented to ER in Oct.2024 with a large abdominal mass, pain and ascites. He was diagnosed with Stage 4 Diffuse Large B-Cell Lymphoma He had very bad side effects with 1st cycle of R-CHOP chemo and did not want to repeat any more chemo treatments. I don't know how they found me, but in early January 2025 we started: Ivermectin 1mg/kg/day Fenbendazole 1332mg/day RESULTS after 3 months: CT showed: "Significant treatment response. Mass-like conglomerate in the left abdomen on previous exam demonstrating significant improvement. Minimal residual mesenteric nodularity measuring 3x2cm" My Take…. Ivermectin and Fenbendazole are often dismissed as not having had any effect on the cancer when the patient also takes chemo. “Chemo did all the work”. But when there is no chemo, and the cancer shrinks or disappears, the critics are silent. There was no chemo in this case and the patient is almost cancer free after 3 months of Ivermectin and Fenbendazole only. Horrible side effects with chemo. No side effects with Ivermectin and Fenbendazole. We're going for "Cancer Free" on the next scan. I have had several Lymphoma success stories like this already. In this case, the patient was more than willing to do chemo but became so sick with the 1st cycle (losing 20+ pounds), that he couldn't do another cycle.


Case 6: 60 year old Oregon woman with Mantle Cell Lymphoma

Dr William Makis shared on X/Twitter in May 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 60 year old Oregon woman with Mantle Cell Lymphoma has up to 96% tumor shrinkage. STORY: 60 year old Oregon Woman was diagnosed with Mantle Cell Lymphoma and bowel involvement. As of December 2024 she was progressing on imaging scans. We started in December 2024:
  • Ivermectin 1mg/kg/day
  • Fenbendazole 888mg/day going to 1332mg/day
RESULTS after 3.5 months (CT results): Neck node: 9mm to 3mm (96.3% shrinkage) Mediastinum precarinal node: 7mm to 3mm (92.1% shrinkage) Right axilla node: 8mm to 4mm (87.5% shrinkage) Abdominal Node: 18mm to 7mm (94% shrinkage) How impressive is that? 88% to 96% tumor shrinkage From the patient: “Beyond the shrinkage, side effects almost non-existent.” “I’ve been feeling energetic and strong enough to do many hours of yard work, gardening, hauling debris and shoveling soil” “Feeling phenomenal”
This doesn’t get talked about nearly enough. Ivermectin and Fenbendazole often REDUCE chemo side effects. This makes a huge difference to the overall Cancer treatment experience.


Case 5: 83 year old Florida man was diagnosed with extensive Stage 3 Follicular Lymphoma (a slow-growing type of non-Hodgkin lymphoma)

Dr William Makis shared on X/Twitter in April 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 83 year old FLORIDA Man with Stage 3 Follicular Lymphoma has a dramatic response (almost 100% resolution), Oncologist refuses to believe it! This is an incredible story for several reasons, but you'll have to read to the end, to find out STORY:
83 year old Florida man was diagnosed with extensive Stage 3 Follicular Lymphoma Oncologist put him on “watch and wait” Patient came to me in early September 2024. We started the Makis Ivermectin Cancer Clinic Protocol in early October 2024:
  • Ivermectin 1mg/kg/day 
  • Fenbendazole 444mg/day 
  • Melatonin 120mg/day
RESULTS after 6 months, on PET/CT (April 2025): "Dramatic improvement in the lymphadenopathy previously seen in the axillary regions bilaterally. Previously the largest right axillary lymph node at approximately 3.4 x 1.9 cm, currently 1.0 x 0.7 cm. Previous maximum SUV of 9.5, currently 1.3" "Dramatic improvement in the retroperitoneal adenopathy" "IMPRESSION: Dramatic improvement of the lymphadenopathy from the neck all the way through the groin. No new or enlarging lymph nodes seen. Only mild activity seen within the right axillary lymph node. Other lymph nodes are not able to be discerned above background significantly improved from the exam September 2024." My Take: I have never seen a Radiology report use the word “Dramatic” three times in the same report. And I have seen 10,000s of PET/CT Reports. Radiologists don’t get emotional with their language.

No chemo. No radiation. Almost all the cancer is gone. But that’s not the best part of the story. Best part is the reaction of the Oncologist: “We discussed findings on PET…which did show improvement in his lymphadenopathy” “We had extensive discussion about PET imaging”

“Discussed waxing and waning nature of lymphadenopathy” TRANSLATION: Waxing and waning = “Cancer comes and goes.” In other words, the results are random. Yes, 99% of the cancer is gone but it was all coincidence. He then refused to do a follow-up PET scan in 6 months! Heaven forbid the excellent results would confuse him even more!

CONCLUSION: This is an incredible story because:

1. No chemo, no radiation, only "watch and wait" from Oncologist

2. 6 months of low dose Ivermectin & Fenbendazole
3. 99% of cancer gone (one mildly active little lymph node remained)

4. Oncologist says cancer comes and goes and attributes the results to coincidence. Chance.

I can assure you that when you have "extensive adenopathy from neck through groin" that is Stage 3 Lymphoma (with SUVmax up to 12.0 on PET/CT), it doesn't just disappear if you close your eyes and wait. 

This Florida Oncologist was so uncomfortable with the excellent results, he won't do a follow-up PET/CT scan. He'd rather close his eyes and pretend. Stay in the dark - it's the world he knows. But guess what, repurposed drugs like Ivermectin and Fenbendazole are revolutionizing Cancer Care and more and more Oncologists are going to get "uncomfortable" with results they don't comprehend...


Case 4:  Female with Hodgkin's Lymphoma (December 2024)

Case testimonial from PerilousPeg (X/Twitter):

"Dr Makis, my daughter just beat Hodgkin’s lymphoma with these drugs, supplements and a few other lifestyle changes. No chemo. No radiation. I have been telling people who are commenting on her video on TikTok with questions qbout ivermectin and fenbendazole to follow you."


Case 3: 70s year old male with Diffuse Large B-Cell Lymphoma (December 2024)

Case testimonial from Dr William Makis (X/Twitter):

IVERMECTIN and FENBENDAZOLE Testimonial - 70s year old patient with Diffuse Large B-Cell Lymphoma - dramatic impact in first two weeks!! 70s year old USA patient recently diagnosed with LYMPHOMA. We started a high dose Ivermectin and Fenbendazole Protocol "We visited my husband's oncologist today and my Husband's blood results were the best we've seen them since the beginning of all this." "He has large B cell lymphoma"
 


Case 2: April, 2021


In 2020 my cancer returned, low grade lymphoma in the neck and chest. I refused to go on another course of chemotherapy and followed the Fenbendazole protocol instead. I decided not to inform the doctors on the protocol I will be using as they would argue that it is a crazy belief with no proof of success.

It is almost a year later today that I received my second biopsy and PET scan results coming back completely clear from any disease, meaning there were no signs of lymphoma found from the neck lymph node that was removed.

Case 1: December, 2021

My twin sister was diagnosed with stage 2 non-Hodgkin’s B-cell double hit lymphoma a few years ago, which is known to be a very aggressive cancer out there. She won the battle, but not so long ago found out that the lymphoma has returned.

As a family we had to weigh the options and see what the next best approach is to this fight against cancer and so her journey started on Fenben. Here is a list of the protocol and other supplements she used and still use today:
  • Fenbendazole (222mg for the first few months and the increased the doses to 444mg/double)
  • CBD
  • Curcumin
  • Vitamin E
  • Additional supplements (recommended by doctors in Mexico)
After she finished her second round of chemotherapy – the PET scan confirmed that she was cancer free, again, after being on the fenbendazole protocol along with the treatment she has been getting since. She still consumes fenbendazole as a preventative measure to ensure the cancer does not return ever again!


Related: Lymphomas: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up (Annals of Oncology 2025)

16. Melanoma

Please refer to Skin Cancer (chapter 25)

17. Multiple Myeloma (3 cases)

Case 3: 49 year old Canadian woman with Multiple Myeloma

Dr William Makis shared on X (September 2025):

IVERMECTIN and FENBENDAZOLE and DMSO Testimonial - 49 year old Canadian woman with Multiple Myeloma has incredible results after 3 months An incredible success story with a very difficult cancer!! We have had some struggles with Multiple Myeloma, a blood cancer that can be incredibly difficult to deal with. But some patients have responded miraculously.
  • Ivermectin
  • Fenbendazole
  • DMSO


Case 2: 60 year old American woman with Multiple Myeloma

Dr William Makis shared on X (May 2025):

IVERMECTIN and MEBENDAZOLE Testimonial - 60 year old American woman with Multiple Myeloma sees improvement in blood work after 5 months! Multiple Myeloma is a very challenging blood cancer. 60 year old American woman was diagnosed with Multiple Myeloma in October 2024 She came to my Ivermectin Cancer Clinic in mid Nov 2024 and we started:
  • Ivermectin 1mg/kg/day
  • Mebendazole 1500mg/day
  • CBD Oil 50mg/day
Five months on Ivermectin/Mebendazole Protocol and we see a trend towards normalization of many blood values such as: Free K/L Light Chain Ratio (most important) Free Lambda Light Chain Gamma protein fraction Total Protein Multiple Myeloma has been one of the more challenging cancers for me to work with. Some patients respond to repurposed drug combination of Ivermectin and Mebendazole and some don't seem to respond at all. The blood cancers in general are really unpredictable but Oncologists are also extremely limited in the treatment options they offer these patients. So the risk/reward ratio here is still heavily skewed towards potential response and benefit with minimal to no side effects.


Case 1: January 2022* with January 2025 update

*Published as a January 2022 case testimonial on Heal Navigator but has been deleted.

18. Myelodysplastic Syndrome

Dr William Makis shared on X/Twitter (January 2025):

IVERMECTIN and FENBENDAZOLE Testimonial - 74 year old former Olympic athlete with Myelodysplastic Syndrome (MDS) post Moderna COVID-19 mRNA Vaccines - first improvement in blood counts in 2 years! Another short but inspiring story! 74 year old former Olympian had two Moderna COVID-19 mRNA Vaccines and recently developed MDS (Myelodysplastic Syndrome). From his wife: "I'm grateful I found you...he is on the Ivermectin and Fenbendazole regime I found on your site" After 1 month: "My husband had his blood tests last week and met with Oncologist today. For the first time in 2 years his blood counts are up and I can only attribute that to your Protocol of Ivermectin and Fenbendazole which he has been following for just a month" And now my favorite part  "You are a miracle worker and I think after the Rogan/Gibson podcast you will be very famous in the USA" Ok that was too sweet of her! The doses used for 1 month:
  • 24mg Ivermectin (daily)
  • 222mg Fenbendazole
These are relatively small doses but still effective! I've had many requests to help patients with Myelodysplastic Syndrome (MDS) and the research is very limited but guess what... several MDS patients and I are now working on it! Many blood disorders respond to Ivermectin and Fenbendazole and this is a hot area of research for those of us staying one step ahead of mainstream oncologists and hematologists!

19. Oral Cancer

Refer to Head and Neck Cancer (chapter 11)

20. Ovarian Cancer Success Stories (6 Cases)

Case 6 - 2025: 60s year old woman from Boston with Stage 4 Ovarian Cancer

Dr William Makis shared on X/Twitter in September 2025:

IVERMECTIN and MEBENDAZOLE Testimonial - 60s year old woman from Boston with Stage 4 Ovarian Cancer reports after 3 months Now here's an interesting story! 60s year old woman from Boston with Stage 4 Ovarian Cancer In late Feb, 2025 she started:
  • Ivermectin (high dose) 
  • Mebendazole (high dose)
Results after 3 months: Metastatic lymph nodes were necrotic. I see this often. After several months of Ivermectin and Mebendazole, when the surgeons go in, they find dead tumors or dead cancer cells. "The cancer cells within the enlarged lymph node which the doctor removed were dead" I'm going to have more stories like this, of unexpected surgical findings after several months of Ivermectin and Fenbendazole or Mebendazole.


Case 5 - 2025: 67 year old WA woman diagnosed with Stage 4 Ovarian Cancer

Dr William Makis shared on X/Twitter in June 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 67 year old WA woman diagnosed with Stage 4 Ovarian Cancer almost cancer free after 2 months! Another Stage 4 Ovarian Cancer Success Story 67 year old WA woman diagnosed with Stage 4 Ovarian Cancer She started low dose Ivermectin and Fenbendazole in January 2025. By end of February 2025, her CA125 rose from 3000 to over 7000. In mid March 2025 we started: Ivermectin 1.5mg/kg/day Fenbendazole 1500mg/day RESULTS after 2 months: "Your customized protocol, combined with metronomic weekly dosing of paclitaxel and carboplatin and some additional naturopathic anticancer treatments, dropped my cancer markers from a high of over 7000 prior to starting your protocol and weekly chemo in early March to a low of 27 on May 12. "A PET/CT scan on 5/12/25 showed NO METASTASIS found and two small areas of increased uptake." "Thank you for giving me my life back!!!! " "I'm no longer spending much of my time in bed and I'm able to walk my dog for an hour! There's no way chemo alone could have done that." My Take… Ivermectin + Fenbendazole + Chemo is a very powerful combination. Some patients want to avoid chemo and I completely understand. But by the time you’re dealing with Stage 4 Cancer, you usually have to throw everything at it.


Case No. 4: 41-year-old Thai female patient diagnosed with recurrent platinum-resistant clear-cell ovarian cancer (PRCCC) in the year 2020

In this case report, we present the case of a 41-year-old Thai female patient diagnosed with recurrent platinum-resistant clear-cell ovarian cancer (PRCCC) in the year 2020. After undergoing chemotherapy for two courses and failing to respond to treatment, she began alternative medicine with repurposing drugs in November 2020. Simvastatin, metformin, niclosamide, mebendazole, itraconazole, loratadine, and chloroquine were also administered. Two months after therapy, a computerized tomography (CT) scan revealed a conflict between a decline in tumor marker levels (CA 125, CA 19-9) and an increase in the number of lymph nodes. However, after continuing all medications for 4 months, the CA 125 level decreased from 303.6 to 54 U/ml, and the CA 19-9 level decreased from 1210.3 to 386.10 U/ml. The patient's EQ-5D-5L score increased from 0.631 to 0.829 (abdominal pain and depression), indicating improved quality of life. Overall survival was 8.5 months, and progression-free survival was 2 months.

Source: Repurposing Drugs in Controlling Recurrent Platinum-Resistant Clear-Cell Ovarian Cancer (Case Rep Oncol Med. 2023)


Case 3 - 2025: 63 year old woman with Stage 4 Ovarian Cancer metastatic to peritoneum (April 2025)

Dr William Makis shared on X/Twitter:

IVERMECTIN and MEBENDAZOLE Testimonial - 63 year old woman with Stage 4 Ovarian Cancer metastatic to peritoneum sees CA125 drop from 2138 to 357, most cancer gone on PET! Beware of inexperienced Integrative MDs who want to play with Ivermectin and Fenbendazole! 

This is a success story that almost wasn't.
63 year old woman with Stage 4 Ovarian Cancer metastatic to peritoneum. In early October 2024, she saw an integrative MD who put her on low dose Ivermectin (24mg) and Fenbendazole 300-600mg, eventually increasing to 1000mg a day. Her CA125 increased from 1097 to 1668 (+ Fenben/IVM) to 2628.5 by mid Nov.2024!

Her CA125 rose from 1668 to 2628 after being on Fenbendazole and low dose Ivermectin for over a month! Then she came to me. 

I switched her from 1000mg Fenbendazole to 1000mg Mebendazole and increased the Ivermectin from 24mg to 72mg. Her CA125 from that point onwards: 2628.5 to 853 to 619 to 357 (!!) PET/CT Scan done March 11, 2025 showed:

“extensive peritoneal carcinomatosis seen previously is essentially resolved” “retroperitoneal adenopathy seen previously has returned to normal”
“left axillary adenopathy seen previously has resolved on both CT and PET images” “most of the pelvic adenopathy seen previously has returned to normal on CT and PET”
“suspected capsular implant seen previously at the posterior aspect of the spleen is no longer visible on CT or PET”
Lesson:

Most Integrative MDs don’t know what they’re doing when it comes to Ivermectin and Benzimidazoles. They get the dosing and combinations wrong. This patient wasn’t responding to low doses of Ivermectin or Fenbendazole and the Integrative MD increased the Fenbendazole dose to 1000mg, but the CA125 rose regardless, from 1097 to 2628!

Ovarian Cancer is known to respond to Mebendazole and Ivermectin but South Korean researchers discovered it doesn’t respond well to Fenbendazole. Some health professionals are attracted to the promise of repurposed drugs but wouldn’t know what to do at the sign of first trouble with their Protocol. Imagine coming to a health professional who has no idea what to do when their Ivermectin Protocol fails. You wouldn't go to an inexperienced hairdresser, barber, or car mechanic, for an important job. And what's more important than Stage 4 Cancer?


Case 2: 40s-year-old Stage 4 Ovarian Cancer (Dec 2024)

According to Dr William Makis (X/Twitter):

IVERMECTIN & FENBEDAZOLE Testimonial - 40s year old Stage 4 Ovarian Cancer patient declared "CANCER FREE" after 2 months 40s year old Stage 4 Ovarian Cancer patient followed at a large US Cancer Centre (Mayo Clinic), reached out to me in July 2024 Patient was diagnosed in Feb.2024 with Stage 4 Ovarian Cancer (High Grade Serous Carcinoma) She had 4 cycles of neoadjuvant chemo, then cytoreduction (surgery) June 24, then plan was for 2 additional cycles of chemo. Post Surgery Cancer Clinic Visit in July 2024: plan was for 2 more chemo cycles - patient then reached out to me after her visit. CA125 on July 15, 2024 peaked at 86.7 (pre-surgery it was 41.7) Even though much of the tumor was removed, the CA125 had jumped from 41.7 to 86.7, indicating rapid cancer growth and spread IVERMECTIN: We started a medium dose Protocol:
  • Ivermectin 1mg/kg/day
  • Fenbendazole 444mg/day
  • Melatonin 100+mg/day
6th cycle of chemo 

Two months later she was CANCER FREE.

Do you think the Chemo did it? The same chemo that after 4 cycles resulted in a CA125 of 41.7? And then rapid progression right after surgery? I don’t think so. It was the combination of chemo + IVERMECTIN Protocol. Now, as of Dec.21, with a CA125 of 16 (in the normal range), she’s been CANCER FREE since end of September.









Case 1: October 2024

According to Dr William Makis (X/Twitter):

IVERMECTIN and MEBENDAZOLE Testimonial in a patient with Advanced Ovarian Cancer. 
3 weeks of high dose regimen results in CA125 cancer marker drop of 30%! 
Ovarian cancer is very responsive to Ivermectin but people forget about Mebendazole (FDA approved version of Fenbendazole). (Hint: combine them) 
We hit this cancer hard and have it on the run 3 weeks in!

  

Note: Although technically mebendazole is not the same as fenbendazole, both mebendazole and fenbendazole are part of a larger group of drugs known as benzimidazole*, which are anthelmintic drugs (i.e., drugs that kill parasitic worms). 

*The class of drugs known as benzimidazoles includes fenbendazole, mebendazole, albendazole and flubendazole. 

Fenbendazole and mebendazole are similar in that they both eliminate parasitic worms, but there is a difference. Mebendazole is approved for human consumption by the FDA, while fenbendazole is only approved for veterinary use and has not been approved for human use.

Mebendazole is the form that is approved for human use while fenbendazole is approved for veterinary use. The main difference is the cost. Mebendazole is expensive ~$450 per pill (two pills of mebendazole cost just $4 in the UK.), while fenbendazole is inexpensive ~48 cents per 222 mg free powder dose (Williams, 2019). Albendazole is the form used to treat intestinal parasites in India and these cost 2 cents per pill. 

While most of the pre-clinical research uses mebendazole, probably because it is the FDA-approved-for-humans form of fenbendazole, virtually most of the self-treating clinical reports involve the use of fenbendazole.


21. Pancreatic Cancer Success Stories (23 cases)

22. Prostate Cancer Success Stories (31 Case Reports)

Read More: Fenbendazole and Ivermectin for Prostate Cancer Success Stories

23. Sarcoma* (4 cases)

*Sarcoma refers to a broad group of cancers that start in the bones and soft tissues. Soft tissues connect, support and surround other body structures. Soft tissues include muscle, fat, blood vessels, nerves, tendons and the lining of the joints. Cancer that starts in the soft tissue is called soft tissue sarcoma.

Case 4 - 2025: 61 year old Texas woman with 2 cancers: Sarcoma of arm metastatic to adrenal, and Neuroendocrine Cancer of the Lung

Case shared by Dr William Makis in August 2025 (X/Twitter):

IVERMECTIN, FENBENDAZOLE and MEBENDAZOLE Testimonial - 61 year old Texas woman with 2 cancers: Sarcoma of arm metastatic to adrenal, and Neuroendocrine Cancer of the Lung reports after 3 months Both are difficult cancers that Oncologists have almost zero success with! STORY: 61 year old Texas woman with 2 cancers: Sarcoma of arm metastatic to adrenal, and Neuroendocrine Cancer of the Lung, came to me for help. Patient took Ivermectin, Fenbendazole and Mebendazole for 4+ months starting March 10, 2025. Oncologist prescribed Keytruda. The synergy is well documented in the literature. Both Cancers responded extremely well: The sarcoma metastatic to adrenal (shrunk 3.4cm to 2.6cm) The Neuroendocrine lung Cancer (lung nodules shrunk 2.0cm to 1.2cm and 1.2cm to 0.7cm All other metastases shrunk as well. This has never been described.


Case 3: Stage 4 Leiomyosarcoma

@BattlingSarcoma shared on X (May 2025):

"@MakisMD I am trying your protocol on Sarcoma (Leiomyosarcoma) - rapid growth, a few inches a month, stage 4. Mebendazole + Ivermectin - no radio, no chemo no immuno, after a month I noticed it stopped growing and I no longer need blood transfusions. I will keep you updated."

Source: https://x.com/BattlingSarcoma/status/1905231385889030146

Useful related discussions under the comment section on X:

"My 14 year old is stage 4 osteosarcoma also. That's great news" (https://x.com/0x_abbie/status)

"Most likely he has Li-Fraumeni TP53 mutation just like me. Sarcomas affect young people. Many people suffered from Sarcoma in my family, chemo/radio did not work on anyone, made things worse." https://x.com/BattlingSarcoma/status/1912133810889671128

"After radio and resection of large retroparitoneal Liposarcoma in 2013, and another resection of recurrent pelvic tumor 2020, still growing. Last scan in 2/2025. measures 6.9 x 8.5 x 15 cm. began IVM, fenben, and niclosamide with alinea and tinidazole. Suggested by Dr Thomas Lodi"
"Also milk thistle and ALA for liver support, Vitamins ABCD and K2 mk7, Quercitin, turmeric, zinc and berberine, beta glucan and Nattokinase. Mostly vegan and juicing. Throwing everything at it."

"My wife has intimal sarcoma of the left atrium in the heat, Mets to bone, lung, scapula and subcutaneous, she had a surgery end Jan by March it had already grown to 4 cm and metastasized, doing chemo and maki’s protocol plus a bunch of supplements Also doing ddw water."

"My mom's BFF has that same cancer. I wouldn't be surprised if you know her only bc there are so few of you w that diag. She's survived 15yrs. She tried that protocol but it didn't take. I'm glad it's work for you! Her go-to for tumor maint/shrinkage is Honokiol and MCP."
"NIH studies on Honokiol shows that it works on the P34 pathway."
https://x.com/Anfoooey/status/1905403782453772592


Case 2: 70 year old woman with Stage 4 Spindle Cell Sarcoma

Dr William Makis updated on X/Twitter (Mar 2025):

IVERMECTIN and FENBENDAZOLE Testimonial - 70 year old woman Stage 4 Spindle Cell Sarcoma with lung metastases has tumor shrinkage! You don't hear many success stories from mainstream Oncology with Sarcoma! There's a good reason for that - chemo almost never works in these cancers. Here is yet another Ivermectin success story: 70 year old woman with Spindle Cell Sarcoma who lost her right leg. Now Stage 4 with lung metastases. She took the Joe Tippens Protocol of Fenbendazole 222mg/day and 12mg Ivermectin/day during chemo and her largest lung metastasis shrunk by 60%. “Had scan after chemo in Aug and had very good unexpected results - shrinkage of tumor by over 60% and disappearance of multiple other lesions.” She then gave me an update a few months later: “Have been off chemo for nearly 4 months, still taking Fenben, etc…and had a scan 3 weeks ago (Dec.2024)…my tumor had actually shrunk again! From 27x18mm to 22.7x12.3mm” Tumor shrunk again from 27x18mm to 22.7x12.3mm (another 60%). This story shows two important things: 1. Combination of chemo plus low dose Fenbendazole and low dose Ivermectin was sufficient to get 60% tumor shrinkage of lung metastases (and resolution of several lesions). Again, the combination of chemo + Ivermectin + Fenbendazole is very powerful, even in a difficult to treat cancer like SARCOMA. These are much lower doses than what I usually use and yet they were still effective. 2. She continued to take Fenben 222mg and Ivermectin 12mg while off chemo and had further tumor shrinkage of another 60%!

Dr William Makis shared on X/Twitter (November 2024):

IVERMECTIN & FENBENDAZOLE Testimonial - 70 year old woman with Stage 4 Spindle Cell Sarcoma gets 60% tumor shrinkage & multiple metastases disappear with low dose protocol 70 year old woman with Stage 4 Spindle Cell Sarcoma originally in the right leg, with lung metastases.
She took the following: 

Palliative chemo (was not expected to help and it's all the doctors had left to offer) 

222 mg Fenbendazole 3 days on / 4 days off (Joe Tippens Protocol) 
12 mg Ivermectin 3 days on / 4 days off 

Unexpected Results: tumor shrinkage by 60% & disappearance of multiple lesions (!!)

My Take… Spindle Cell Sarcoma is a cancer that’s notoriously difficult to treat. The response rate of chemo is on the order of 20% (which means 80% of patients don’t see ANY improvement). The ones who respond see minimal results. To get tumor shrinkage by 60% and disappearance of multiple lesions is stunning. The chemo was palliative and was not expected to help in this case.
 
So yes, it wasn't the chemo. Sorry. And these were VERY LOW doses of Ivermectin & Fenbendazole !! I tend to suggest higher doses as cancer killing with Ivermectin & Fenbendazole is dose dependent.




Case 1: September, 2023


Condition: Alveolar Rhabdomyosarcoma (Bone and Muscle cancer)

When my 13 year old son was diagnosed, I basically became a cancer researcher!
I discovered a few new very promising treatments that are close to being ready for pediatric use, and I also came across Joe Tippen’s story. I joined a couple of large, international Facebook groups related to the Protocol, which are by far the most positive of all of the cancer-related groups I’m in, and have the most success stories. I connected with a mom in the group whose 2 year old has the same type of cancer as my son, which had spread to his lymph nodes during frontline chemotherapy treatment. She started him on Fenben and his next 2 scans so far have been clear!
I would do anything to help my son beat the odds, and I came to the conclusion that it would be far more dangerous NOT to give him repurposed meds than to give them.
My husband supported my decision, but wanted some medical oversight, which we have received from Heal Navigator.
We noticed an improvement in our son’s energy level and general health after just 2 days of giving him the Fenben! He had zero side effects, besides feeling a lot better.
I hope and pray that is a sign that it’s doing what we need it to! If you’re hesitating about getting started, I would encourage you to go for it!

Protocol components used: Fenbendazole , Curcumin, Milk thistle, Ivermectin, Vitamin D3, Claritin, Melatonin, Propranolol, Niclosamide, Mushroom blend, Omega 3, Papaya Leaf Extract as needed to raise blood counts.

Conventional treatments: Radiation, Chemotherapy.

24. Skin Cancer and Fenbendazole (10 cases)

Case 10 - 2025: Metastatic Melanoma NRAS Variant, age 69, Male

Shared by Ben Fen in August 2025:

This Case Report of PC, as told by his wife, documents the case of a 69-year-old male, with Stage 4 metastatic melanoma who achieved a complete metabolic response. PC initiated treatment with fenbendazole, resulting in a significant partial response, including the resolution of multiple metastatic sites. The subsequent addition of combination immunotherapy (Nivolumab/Relatlimab) led to the complete resolution of all detectable disease. This case highlights a successful therapeutic sequence, demonstrating the profound anti-neoplastic effects of fenbendazole and its synergy with checkpoint inhibitors in achieving a durable, cancer-free outcome.

Clinical Timeline: Diagnosis, Treatment, and Response

Jan 2023: Diagnosis: Stage 4 metastatic melanoma confirmed. Widespread disease in clavicle, aorta, abdomen, leg, mediastinum, and a suspicious brain lesion.

Initiated Fenbendazole: 222 mg daily. PC begins self-directed therapy.

May 2024: PET-CT: Resolution of clavicular and mediastinal metastases. Persistent para-aortic disease (SUV max 7.04). Unremarkable brain CT.

Fenbendazole 222 mg daily. Significant partial response to fenbendazole monotherapy.

June 8, 2024: Genetic testing confirmed NRAS mutation, CDKN2A gene )p.M53l variant).

June 10, 2024: Blood Panel: Transient elevation of liver enzymes (ALT/AST).

Fenbendazole 222 mg daily. Liver enzyme elevation likely due to tumor lysis; therapy continued.

June 20, 2024: Dose Adjustment: Fenbendazole increased to 444 mg daily (222 mg twice per day). Fenbendazole Dose Escalation. Dose increased to drive further therapeutic response.

Sept 17, 2024: PET-CT: Resolution of cutaneous leg lesion. Further reduction in para-aortic node (SUV max 5.89). No new disease.

Fenbendazole 444 mg daily. Continued favorable response.

Blood Panel: Liver enzymes returned to normal range.
Fenbendazole 444 mg daily. Normalization confirms the transient nature of the enzyme elevation, ruling out hepatotoxicity.

Sept 20, 2024: Immunotherapy Initiated: Began combination therapy with Nivolumab/Relatlimab (monthly infusions).

Immunotherapy Introduced. Standard-of-care immunotherapy added to consolidate gains.

Jan 10, 2025: CT & PET Scans: No nodal or metastatic disease detected. Para-aortic node no longer avid (SUV max 2.3). Clear brain scan.

Immunotherapy complete. Complete Metabolic Response Achieved.

May 15, 2025: Follow-up: PC is active, in excellent health, and remains cancer-free. Immunotherapy-induced colitis fully resolved. No active cancer treatment.

Durable Complete Response.

Case Presentation and Clinical Course

Initial Diagnosis and Fenbendazole Monotherapy: In January 2023, a 69-year-old male (PC) with a 35-year history of surgically managed melanomas was diagnosed with Stage 4 metastatic disease. PET-CT imaging confirmed extensive metastases involving the left supraclavicular fossa, mediastinal lymph nodes, para-aortic arch, abdomen, a cutaneous leg lesion, and a brain lesion of high concern. PC commenced self-administered fenbendazole at 222 mg daily. Over the next 16 months, he achieved a significant partial response on fenbendazole monotherapy. A PET-CT in May 2024 confirmed the complete resolution of metastases in the left supraclavicular fossa and mediastinal nodal stations.

Dose Escalation of Fenbendazole and Continued Response: In June 2024, a routine blood panel revealed a transient elevation in liver enzymes (ALT/AST). This was interpreted as a consequence of tumor lysis rather than drug toxicity. The fenbendazole dose was confidently increased to 444 mg daily. By September 2024, follow-up imaging demonstrated further disease regression, including resolution of the cutaneous leg lesion and a decrease in the metabolic activity of the remaining para-aortic lymph node (SUV max reduced from 7.04 to 5.89). Concurrently, his liver enzymes had normalized, validating the decision to continue and escalate the fenbendazole dose.

Introduction of Immunotherapy and Complete Response: With the majority of the disease burden eliminated by fenbendazole, combination immunotherapy (Nivolumab/Relatlimab) was introduced in September 2024 to target the residual disease. PC experienced a significant adverse event of immunotherapy-induced colitis, which persisted for approximately eight months before resolving. Follow-up scans in January 2025 revealed a complete metabolic response. All evidence of nodal or metastatic melanoma was absent. The metabolic activity in the previously persistent para-aortic lymph node had fallen to background levels (SUV max 2.3). As of May 2025, PC remains in excellent health, active, and cancer-free.

Conclusions: The Foundational Role of Fenbendazole

The clinical timeline establishes that fenbendazole monotherapy was responsible for the substantial initial tumor debulking. By the time immunotherapy was introduced, the majority of the metastatic burden had resolved, indicating fenbendazole acted as the primary therapeutic agent in this case. This initial response likely created a more favorable tumor microenvironment for immunotherapy. By inducing immunogenic cell death through mechanisms such as microtubule disruption, fenbendazole enhanced the presentation of tumor neoantigens, effectively "priming" the remaining disease for a robust and complete response to checkpoint inhibition.

Tumor Lysis as the Potential Cause of Transient Liver Enzyme Elevation

The transient elevation of liver enzymes is attributed to the metabolic stress of processing significant tumor lysis, a phenomenon observed in other cases of effective fenbendazole treatment. The resolution of the transaminitis (liver enzyme fluctuation), even after a fenbendazole dose escalation, coincided directly with the reduction in overall tumor burden. This temporal relationship suggests that the enzymatic rise was a consequence of therapeutic efficacy, not drug-induced liver injury. The return of AST/ALT to within normal limits despite continued fenbendazole administration supports the assertion as well.

This case documents a complete and durable metabolic response in a patient with advanced metastatic melanoma. A sequential treatment protocol, initiating with fenbendazole to debulk the tumor followed by consolidation immunotherapy, proved to be a highly effective strategy. This outcome underscores the potent anti-neoplastic capability of fenbendazole and its synergistic potential with modern immunotherapies.

PC’s wife reports that he is presently a “box of birds” after coming through this experience in successfully eradicating his cancer.


Case 9: Ivermectin & Fenbendazole Testimonial - Stage 4 Malignant Melanoma
  • Source: https://t.co/WGllfQFysg
  • Description: Posted on March 29, 2025, by
    @MakisMD
    , this highlights an Australian man with Stage 4 malignant melanoma with metastases to multiple sites. He reportedly achieved a "cancer-free" status after 12 months using ivermectin and fenbendazole.

Case 8: Stage 4 melanoma with mets to lymph nodes

Shared by DavidCarl (X/Twitter):

"As I’ve told you, my wife had stage 4 melanoma with mets to lymph nodes. She started taking ivermectin before you released your protocols, 1mg/kg. Weeks later you published your protocols and I bumped her to 2mg/kg. I added 444 mg of fenbendazole. Her last pet scan was approximately 6 months where she was cancer free. Her oncologist was all smiles, but I never told him I was giving her the protocol. She continues to take .5mg/kg of ivermectin 6x week and 3x week of 444 mg fenbendazole. She was taking immunotherapy for about a year before I read about ivermectin. Her lesions were having moderate response to the immunotherapy per pet scans. After putting her on ivermectin, 45 days later with a pet scan she presented cancer free. We were blown away. I almost cried. Doctor this is the hope you’ve given us. Your stories continue to give my wife confidence. It is like a big dark cloud we lived with was lifted."


Case 7: Stage 3B Melanoma with liver failure

Shared by Dr William Makis (X/Twitter) - February 2025:

IVERMECTIN, FENBENDAZOLE and MEBENDAZOLE Testimonial:

FROM THE BRINK OF DEATH - Stage 4 Melanoma patient with extensive liver metastases given 2-3 days to live! Survives and most metastases are gone! 

If you only read 1 of my testimonials EVER, make it this one. Canadian patient had Stage 3B Melanoma 5 years prior. In Dec.2024, he presented to emergency in liver failure.
"He was told (by an Oncologist) Dec.2nd that he had 2-3 days to live and was in liver failure as his entire liver was consumed with tumors". 

(Diagnosis: Stage 4 Melanoma recurrence with extensive liver metastases & liver failure) “The only thing he (Oncologist) could suggest to try was Bractovi and Mektovi but has never given it to anyone with their liver in such bad shape – we are told that it is completely taken over with both cystic and solid lesions. Against our belief we were faced with a ‘try or die….” "He was given 1-2% chance with Braftovi/Mektovi so started that Dec.3rd" "I reached out to you shortly thereafter and started your protocol. The CT results from Jan.30th (2025) that I am sending you show significant regression or complete resolution!!!" 

Braftovi/Mektovi - 59 days 
Ivermectin - 43 days 
Mebendazole - 38 days 
Fenben - 28 days MAKIS IVERMECTIN CLINIC PROTOCOL Implemented: 
Ivermectin 1mg/kg/day (43 days) 
Mebendazole 400mg/day (38 days) 
Fenbendazole 444mg/day (28 days)

Yes, you read that correctly. This is what's called "weighing the risks and benefits".

CT RESULTS: "All previously detected hepatic lesions have markedly regressed or resolved." "Excellent response to the interval instituted treatment regime, where there has been marked regression of the metastatic liver disease with associated significant reduction in the associated hepatomegaly. "There has been significant regression of the metastatic lymphadenopathy of the root of the small bowel mesentery" "there has been complete resolution of the underlying anasarca and ascites" "There are presently no signs of acute intra-abdominal/pelvic process observed" ----- My Take… Do you know what is probably the single most frustrating question I get every day? “Is Fenbendazole safe? My doctor told me it will damage my liver!” "My doctor told me Fenbendazole will destroy my liver" Let me summarize: Stage 4 Melanoma patient with extensive liver metastases told he had 2-3 days left to live... in LIVER FAILURE...
Implemented a Protocol with Ivermectin, Fenbendazole and Mebendazole! 

And is alive 2 months later with all metastases either shrunk or gone! FROM THE BRINK OF DEATH… If anyone ever tells you that Fenbendazole or Mebendazole will damage your liver, know that they are lying to you, and if you want to, show them this story!







Case 6: Basal Cell Carcinoma (BCC)

In this December 2024 case report published by Canadian Oncologist Dr. William Makis, we note the pictorial resolution of basal cell cancer [BCC] to the point that the patient may have to cancel his appointment for a planned surgical removal. One cannot surgically remove a basal cell cancer [BCC] that no longer exists.

This gentleman reports he is a long-time reader of Dr. Makis and was particularly interested in his reports of Fenbendazole and Ivermectin. He contracted basal cell cancer on his face in February or March of 2024, and did what most of us would do - he booked an appointment with his GP in June 2024, apparently the first available.

The soonest he could get scheduled for the Dermatology referral was sometime in November. Having nothing to lose, he decided to apply Fenbendazole paste per the articles he had previously read, and to his pleasant surprise the persistent non-healing skin cancer of seven months began to shrink in size.

FenBen Treatment from September 25 through October 28, 2024

By the time of his November Dermatology appointment, there was very little to biopsy, yet it was done. He reports the Dermatologist was not the least bit interested in his tumor shrinkage with the Fenbendazole paste. Instead, the Dermatologist booked him for a tumor removal appointment three months later in February 2025.

The patient continued to apply the paste for the next month following the November biopsy, and here is what the BCC looked like as of December 6, 2024.


Result of FenBen Topical Treatment from September 25 through December 6, 2024

He writes,

“I’m still treating it once a day with Safeguard 10% Fenbendazole and it seems to still be improving. So I’m undecided about whether I need to have anything removed. I guess I’ll see how it goes over the next while. Maybe it’s deep into the tissue despite having improved the surface cells. No idea.”

Dr. Makis writes in response that patients who take matters into their own hands seem to do better.


Case 5:

source: https://substack.com/home/post/p-155091883


Case 4: Melanoma (Skin Cancer)

Shared by Dr William Makis (X/Twitter) - Last Edited: October 2024:

FENBENDAZOLE Testimonial in Stage 4 Melanoma Cancer patient - didn't listen to Oncologist's advice to stop Fenben, and is now cancer free.

There is a key lesson here. The Oncologist gave the opposite advice of what was good for the patient. That's because the Oncologist was following Cancer Guidelines set by Big Pharma (like Pfizer). If this patient had followed his Oncologist’s advice and stopped the Fenbendazole, he would still have active Stage 4 melanoma metastases with a much worse prognosis. Maybe he'd already be dead. How do you know if you have a good Oncologist? Ask them how many COVID-19 Vaccines they took! The only correct answer is "0".



Case 3: May, 2022 - Squamous Cell Carcinoma


In September 2021, I went to the cancer clinic to get my second PET scan done after receiving the news in March 2021 that I have been diagnosed with cancer, and learnt that day that my tumor has shrunk to half the size it first was. There were still signs of lymph nodes increasing or being classified as unknown results. I continued the use of the fenben protocol along with a whole bunch of other supplements to take on a daily basis, as within 5 months results improved in comparison to a whole year of fighting off the protocol before with little to non improvement in results. I strongly believe in this protocol and in case you wondered – I am not on any chemotherapy/radiation/immunotherapy or any other western medicine use – this is a full on natural and holistic journey I went on, and I am happy to share my current protocol with all cancer patients out there:
  • Serrapeptase (at midnight)
  • Vit D & K2, Tudca 500mg, Graviola 1ml (on an empty stomach)
  • Varies supplementation with breakfast (like Vit C & B complex, probiotics, fish oil, curcumin, etc. along with fenben 888mg)
  • Multi-vitamin, turkey tail extract, fenben 888mg, and B17 apricot seed (with dinner)
  • Some more other supplements just before bed (like magnesium, Vit C, Graviola, high dose of melatonin, coffee enemas, etc)
  • Detox baths (1 x week)
  • Frequency music (before bed designed to kill cancer cells)
  • Mainly following a plant-based diet
  • Protein intake is limited to certain meats
  • Fresh whole foods/vegetables
  • Healthy fats only
I trust that this protocol I am following will guide a lot of people out of their state – just belief and trust the process along with the support from others who have been through this before. Good luck.

Case 2: October, 2022

In February and March of this year I was diagnosed with stage four melanoma. It had metastasized to my brain, lymph nodes, right lung, adrenal gland and right hip. My daughter pointed me to Joe’s story and this site. I started taking the fenbendazole protocol even before my oncologist gave me her treatment plan using Immuno therapy. The oncologist said that it had about a 30% success rate but not to expect any great results on the first scan after 4 treatments.

I had a PET scan last week and the results were almost too good to be true. Cancer basically gone. The tumor in my right lung had shrunk to less than half the size it was on the first PET scan. The uptake on that tumor decreased from 19.9 to 2.6. I was told by her that an uptake of less than 4.0 is no longer considered as cancerous.

I have been on the fenbendazole protocol for 166 days now. I received 4 immunotherapy injections using 2 different drugs. I can’t say for sure what definitively gave me these great results. Draw your own conclusions but I think the fenbendazole was largely responsible for the great results.

Case 1: January, 2022

At first me and my partner were unsure about trying alternative treatments in addition to the radiation my partner receives. With the help from a holistic healer and referrals from a couple of people in our community, we found out about the fenbendazole protocol and started to add the protocol along with a few other supplements to my partner’s daily intake/routine to aid in fighting the skin cancer on his neck.

25. Throat cancer

Refer to "Head and Neck" Cancer.

26. Thymus cancer

October, 2022

Condition: Thymus cancer

Was diagnosed with Thymic Carcinoma 06/2022. Just finished week 8 of 12 week chemotherapy. I have been taking fenbendazole, curcumin, vit D & K, and CBD oil. We will do another PET scan in October and I fully expect the tumors to be completely gone or greatly reduced. Will update with the results asap. Blessings to all.

27. Thyroid Cancer


28. Turbo Cancer (Aggressive Cancer)

Experts are seeing a puzzling rise in cancer in people under 50 that appears biologically different from late-onset cancers. While some claim cancer rates have been rising for decades and attribute the increase to sugary drinks, lifestyle, and sleep disruptions, others say mRNA COVID-19 vaccines have caused an emergence of “turbo cancers”—and U.S. regulatory agencies have not addressed the ever-growing problem.  


29. Uterine Cancer (6 cases)

Uterine cancer, also known as womb cancer, includes two types of cancer that develop from the tissues of the uterus. Endometrial cancer forms from the lining of the uterus, and uterine sarcoma forms from the muscles or support tissue of the uterus.

Refer to "Endometrial Cancer" case reports above.

Conclusion and Key Takeaway

Keep in mind that these references are based on case reports, which offer preliminary evidence. Critics may dismiss them as pseudoscience or low-quality data or even misinformation. However, these testimonials could represent just the tip of the iceberg—an emerging frontier that science is only beginning to explore.

For a more comprehensive understanding, it's worth looking into additional research studies and clinical trials. As always, consult with your healthcare provider(s) before making any treatment decisions, as close monitoring and personalised care are essential.


Disclaimers:
  • Statements on this website have not been evaluated by the Food and Drug Administration. The contents of this website is for educational and informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis or treatment.
  • Please do not consider this guide as personal medical advice, but as a recommendation for use by professional providers. Consult with your doctor and discuss with her/him. Our aim here isn't to replace your doctors' advice. It is intended as a sharing of knowledge and information. Do take note that cancer is a continuous struggle between the immune system and the cancer cells. Cancer treatments are meant to assist the immune system in this battle. Any potential treatment—whether conventional or complementary—must be evaluated on a case-by-case basis, with careful consideration of the benefit-risk ratio to ensure both safety and efficacy.
  • The case reports presented reflect the real-life experiences and opinions of other readers or users of the website. The experiences of those readers or users are personal to those particular readers/users and may not necessarily be representative of all readers/users. We do not claim, and you should not assume, that all other readers/users will have the same experiences. Do you own research, consult with relevant medical professionals before attempting to self-treat for any condition.
  • Cancer treatment should be part of a multi-modal approach in order to provide the best possible outcome. Diet and lifestyle changes are meant to run alongside conventional treatment. They are complementary, not alternative. 
  • Cancer care is a team effort with the patient at the centre. Care should be supervised and coordinated by a primary healthcare provider. Patients with cancer should consult with their regular oncologist as well as an integrative provider/oncologist, in addition to their primary care provider and the supporting nurses, dieticians and other allied healthcare professionals.
  • While the term 'alternative' might imply opposition to conventional oncology, we prefer 'complementary,' 'integrated,' or 'holistic.' These terms better reflect the role of these strategies as part of a personalized value-added menu of strategies, ensuring the most effective and safe solutions for patients.
  • Integrating a repurposed drug doesn't mean rejecting modern medicine — It enhances it and offers a more comprehensive approach to wellness and healing. By combining conventional cancer management with root-cause resolution, this model creates a path to sustained recovery and resilience. 

Sources and References: 

Find Integrative Oncologists in USA, Mexico, Europe or Asia

While the potential anti-cancer properties of fenbendazole are intriguing, it’s crucial to approach with caution.

Consulting with an integrative healthcare expert is key to crafting a Fenbendazole protocol tailored to your unique health requirements. 


New & Improved Joe Tippens Protocol

In 2016, Joe Tippens was diagnosed with non-small-cell lung cancer with extensive metastatic disease. At the advice of a veterinarian friend, he took Fenbendazole together with nanocurcumin, and three months after starting these drugs his PET scan was completely clear.

Below is a modified version of the Joe Tippens protocol, a synergistic combination of fenbendazole, ivermectin and nutraceuticals, updated based on the ivermectin and mebendazole based protocol published in the Journal of Orthomolecular Medicine (2024):
  • Ivermectin (24 mg, 7 days a week) or in the case of severe aggresive cancers up to 1mg/kg/day.
  • Mebendazole (Dose of 200 - 400 mg/day) or Fenbendazole, commonly taken at 300 mg for six days a week, with doses increasing to up to 1 gram in cases of aggressive cancers.
  • Vitamin D (62.5 mcg [2500 IU] seven days a week).
  • Bio-Available Curcumin (600 mg per day, 7 days a week). 
  • Enhanced absorption Berberine (500 mg per day) to starve your cancer of sugar.
  • Diet and Lifestyle: Eliminate sugar consumption as supported by the BMJ 2023 umbrella review, which recommends reducing free and added sugars to below 25 g/day and limiting sugar-sweetened beverages to less than one serving per week to reduce adverse health effects. Adopt a whole-food diet and avoid ultra-processed foods, as recommended by the BMJ 2024 guidelines. Additionally, prioritise adequate sleep and effective stress management to support overall health.
*Notes:
  • Please note that this protocol now includes the vital Vitamin D addition, with the one day off for the fenbendazole administration. This protocol represents the most comprehensive and cutting edge repurposed drug and vitamin treatment approach to date.
  • If you are taking ivermectin and mebendazole, you might not need fenbendazole. Consult your doctor.
  • Vitamin E: Removed from the protocol (Joe Tippens, July 22, 2020) due to interactions (e.g., with blood thinners).



Ivermectin and mebendazole, both approved for human use, are now available in the U.S.

Researched and approved by Dr. Peter McCullough.
  • Prescribed by licensed medical professionals
  • Compounded and dispensed by a licensed US-based pharmacy
  • Approved for human use
Where to buy Ivermectin and Mebendazole Formula: Available on The Wellness Company's website. Here is the link: Ivermectin and Mebendazole.

Comments

Labels

Show more

Archive

Show more

Popular posts from this blog

Ivermectin and Fenbendazole: Treating Turbo Cancer - Dr William Makis

Ivermectin, Fenbendazole and Mebendazole in Cancer: 2024 Peer-Reviewed Protocol in Cancer

Fenbendazole Joe Tippens Protocol: A Step-by-Step Guide (2025)

Best Ivermectin Dosage for Humans with Cancer or Different Cancer Types (2025)

Ivermectin Tested against 28 types of Cancer: Most Sensitive vs Least Sensitive

DMSO 101: Benefits, Uses, Dosage and Side Effects (2025)

Best Fenbendazole Dosage for Humans: Safety, Side Effects and Efficacy Examined (2025)

Fenbendazole and Ivermectin for Prostate Cancer Success Stories: 34 Case Reports Compilation (September 2025 Edition)

Fenbendazole, Ivermectin and Mebendazole for Breast Cancer Success Stories: 49 Case Reports (October 2025)