Fenbendazole and Ivermectin for Pancreatic Cancer Success Stories – 13 Case Reports (2025)

Can Fenbendazole and Ivermectin play a key role in treating Stage 4 Pancreatic Cancer?

Several peer-reviewed papers and case studies (below) strongly suggest that it might. 

• Ivermectin, Fenbendazole and Mebendazole in Cancer: 2024 Peer-Reviewed Protocol in Cancer
• Ivermectin and Cancer: 15 Anti-cancer Mechanisms of Action
• FENBENDAZOLE and CANCER - 12 Anti-Cancer Mechanisms of Action

Exploring Fenbendazole as a Potential Treatment for Stage 4 Pancreatic Cancer

Pancreatic cancer is one of the most aggressive and challenging cancers to treat, especially in its advanced stages. With conventional treatments often offering limited success, many patients and researchers are exploring alternative and adjunct therapies. One such emerging option is fenbendazole, an anti-parasitic drug traditionally used in veterinary medicine, which has recently gained attention for its potential anti-cancer properties.

Using SEER* 5-year survival statistics: Public median survival ~3–6 months post-diagnosis vs. multiple cases reporting survival beyond 1 year with fenbendazole below.

*The Surveillance, Epidemiology, and End Results (SEER) Program provides information on cancer statistics in an effort to reduce the cancer burden among the U.S. population. SEER is supported by the Surveillance Research Program (SRP) in NCI's Division of Cancer Control and Population Sciences (DCCPS).

Pancreatic Cancer Awareness

In this article, we examine case studies of fenbendazole and its possible role in managing late stage pancreatic cancer. Could this repurposed drug offer new hope for patients seeking additional treatment options? Let’s take a closer look.

 

Pancreatic Cancer Success Stories

Case 13: 57 year old California man with Stage 2 Pancreatic Cancer

Dr William Makis shared on X (Twitter) in April 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 57 year old California man with Stage 2 Pancreatic Cancer (history of two Moderna mRNA vaccines) has excellent response after only 2 months!

"His oncologist is aware of the supplements he is taking (she's not so happy about it)"

I almost fell off my chair...I love when my patients write to me about their interesting interactions with their Oncologists! But let's go to the beginning... 57 year old California man was diagnosed with Stage 2 Pancreatic Cancer with a 3.6cm mass in the head of the Pancreas. He had two Moderna mRNA Vaccines. Was this an mRNA Induced Turbo Cancer? Possibly. December 2024: "After waiting for a chemo date and without a Protocol in place, his CA19-9 rose from 1341 to 2244 in 11 days!" Yes, very possibly a Turbo Cancer. This kind of growth in Cancer markers is absolutely frightening... He came to me in early January 2025. He started chemo on Jan.29, 2025 along with: 

• Ivermectin 96mg/day
• Fenbendazole 1776mg/day

Those of you who know me, know I prefer to work with higher doses. The Stanford Group used Fenbendazole 1000mg/day but for Pancreatic Cancer, I like to go higher. RESULTS after 2 months: CA19-9: 2244 to 914 to 1328 to 601 to 426 (after 2.5 months) PET/CT: Pancreatic mass SUV 5.0 to 2.7 (46% drop in metabolic activity) These are incredible results for a Pancreatic Turbo Cancer! Cancer blood markers dropped 81%, metabolic activity of pancreatic tumor dropped 46%!

Case 12: 46 year-old-male with Stage 4 Pancreatic Cancer

Dr William Makis shared on X (Twitter) in April 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - Stage 4 Pancreatic Cancer post Moderna mRNA Vaccines - 46 year old USA patient improves dramatically after only 2 months! All tumors and metastases shrink! This family has two incredible Pancreatic Cancer success stories from my Ivermectin Cancer Clinic! STORY: 46 year old man (USA) was diagnosed with Stage 4 Pancreatic Cancer metastatic to lymph nodes, liver and bones. He had two Moderna COVID-19 mRNA Vaccines in 2021. (Possible Turbo Cancer) Oncologist started Folfirinox and Gemcitabine

We started the Makis Ivermectin Cancer Clinic Protocol:

• Ivermectin 1.5mg/kg/day 
• Fenbendazole 1500mg/day

A follow-up PET/CT was done after 2 months on Ivermectin Protocol RESULTS: After 2 months on Ivermectin and Fenbendazole:

Pancreatic head mass shrunk by 21% with 56% drop in metabolism
Lymph node metastases improved or resolved

Liver metastases reduced by 40-45% in number.
Bone metastases improved or resolved.

You never see this kind of response with just chemo. In only 2 months!! This patient was referred by a family friend: "Hi Dr.Makis...just want to let you know that my uncle who has been on your Protocol since September 1st has seen drastic improvement, his most recent scan showed the tumor in his pancreas has shrunk. This is something the oncologists said was nearly impossible.

However, the main reason for my email is to try and help a family friend with HIS cancer...he has stage 4 pancreatic cancer which has spread to many other organs, his situation is somewhat dire". That's the case described here with the pancreatic mass and all metastases shrinking after 2 months on Ivermectin and Fenbendazole.

Case 11: 53 year-old-male with Stage 4 Pancreatic Cancer

Dr William Makis shared on X (Twitter) in April 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 53 year old man with Stage 4 Pancreatic Cancer reports back after first 3 weeks... 

53 year old man with a new diagnosis of Stage 4 Pancreatic Cancer (metastatic to liver) and rising CA19-9. Got started on 120mg Ivermectin and 1332mg Fenbendazole as soon as possible. CA 19-9 dropped 43% from 154 to 87 after 3 weeks!! From the patient: "He began full 120mg Ivermectin + 1332mg Fenbendozole et al approx. March 25. So in about 3 weeks from start of full Makis protocol, BIG DROP in CA 19-9 and Liver ALT went normal too!!!
Even though Liver Mets and legions seen few weeks ago on MRI scan. Everything appears to be clearing rapidly! Anxiously awaiting next scans to see if tumors/legions shrinking but I wanted to reach out and thank you for your tireless efforts!!!
You are making a HUGE difference in the world!!!"

Case 10: 77 year old Stage 4 Pancreatic Cancer

Dr William Makis shared on X (Twitter) in April 2025:

FENBENDAZOLE and MEBENDAZOLE Testimonial - 77 year old Stage 4 Pancreatic Cancer patient sees 99.9% drop in CA19-9 levels and shrinkage of tumors by 70 to 87%! 

Another incredible Stage 4 Pancreatic Cancer success story!  This one may surprise you because Ivermectin was not involved. 

77 year old Stage 4 Pancreatic Cancer patient started taking a regimen of Mebendazole and Fenbendazole.

1000mg Mebendazole in the morning 

888mg Fenbendazole in the afternoon 

RESULTS: 

- CA19-9 dropped from 44960 to 21 (99.9% drop) 

- small liver lesions resolved - large liver lesion shrunk from 3.6cm to 2.4cm (70% tumor volume decrease) 

- 2nd liver lesion shrunk from 2.4cm to 1.2cm (87% tumor volume decrease) 

"His Doctors are amazed. His main oncologist told him in 35 years he does not remember a person with results like this. He went as far as calling the results a miracle." 

" Dr. Makis, you have saved countless lives with your message, you are the epitome of what health care should be. Thank you" 

Very nice to see a Stage 4 Pancreatic Cancer testimonial using Fenbendazole and Mebendazole!

Case 2: Stage 4 Pancreatic Cancer

Dr George Fareed shared on X/Twitter (January 2025):

"Patient with stage 4 pancreatic cancer today txted: Great news. Tumor is much smaller than before. 5.4cm to 3.3 cm. I’ve gained about 12 lbs. He continued IVM/mebendazole protocol started 10/24 as well as chemo started 11/24."

 

Case 3: 40s-yr-old male with Stage 4 Pancreatic Cancer (December 2024)

Case shared by Dr William Makis (X/Twitter):

IVERMECTIN and FENBENDAZOLE Testimonial - 40s year old man with Stage 4 Pancreatic Cancer post 2x Pfizer mRNA Vaccines, sees 91% drop in CA19-9* in 2 months! Possible case of Turbo Cancer post 2 Pfizer COVID-19 mRNA Vaccines 40s year old man diagnosed with Pancreatic cancer in 2022 post 2 Pfizer COVID-19 mRNA Vaccines. Had Whipple procedure, then 12 cycles of chemo and 2 months of radiation. Treatments ended May 2023.

Recurrence in June 2024 (mass encasing SMA & liver lesions) Restarted chemo in July 2024 but chemo wasn't working. CA19-9 was skyrocketing. I was consulted in October 2024. We immediately started high dose Ivermectin (up to 2mg/kg/day) and high dose Fenbendazole (up to 888mg/day) 2 months later: (you can read the email for yourself) 91% drop in CA19-9 cancer blood markers! 28340 to 2699. This is my favorite part, seeing results like this, especially when chemo was failing. It's worth persevering on high doses of Ivermectin, Fenbendazole or Mebendazole, and i know it isn't always easy. We struggle with this sometimes.

*Note on pancreatic cancer marker (CA 19-9):

A CA 19-9 test measures the amount of a protein called CA 19-9 (cancer antigen 19-9) in a sample of your blood. CA 19-9 is a type of tumor marker. Tumor markers are substances made by cancer cells or by normal cells in response to cancer in your body. Healthy people can have small amounts of CA 19-9 in their blood. High levels of CA 19-9 are often a sign of pancreatic cancer. But high levels can also be a sign of other types of cancer or certain conditions that aren't cancer. For example, gallstones, pancreatitis and cirrhosis of the liver can cause high CA 19-9 levels.

Case 4: Pancreatic Cancer patient who didn’t respond to first line chemotherapy (November 2024)

Case shared by Dr William Makis (X/Twitter):

IVERMECTIN and FENBENDAZOLE Testimonial - Pancreatic Cancer - CA19-9 drops 1349 to 450 in less than 2 months - loving daughter outsmarts Oncologist! This is a Pancreatic Cancer patient who didn’t respond to first line chemotherapy, the best chemo that the Oncologists had in their arsenal. Lessons: Oncologist with his best medical training and best medicine = Pancreatic tumor grows 4.1cm to 4.6cm and CA19-9 rises 880 to 1349 Loving daughter with internet and dog medicine = CA19-9 drops 1349 to 450. Low doses can work: 

12mg Ivermectin (I would have done 60mg) 

444mg Fenbendazole 4/7 

(I would have done 6/7 or even 888mg) She still did brilliantly. Work with what you have and don't be afraid. The daughter outsmarted the best Oncologists with their best medicine!

Case 5: 50s man with Stage 3 Pancreatic Cancer (November 2024)

Case shared by Dr William Makis (X/Twitter):

IVERMECTIN and FENBENDAZOLE Testimonial - 50s man with Stage 3 Pancreatic Cancer - incredible response to therapy after 8 weeks - 75% drop in CA19-9 

75% reduction in blood tumor marker CA19-9 after only 8 weeks of high dose Ivermectin and Fenbendazole is wild! We’re certainly on the right track. 

75% of cancer cells may be dead, no longer producing tumor markers. Excellent question and lesson point here. Is it problematic that the tumor is not shrinking yet? 

That takes a bit longer and is a more involved process. That’s why a PET/CT scan would be good here. We could see the metabolic activity of the tumor drop dramatically, suggesting most of the cancer cells are dead, even if the tumor mass hasn’t shrunk yet. 

Some Oncologists are good at ordering them, some aren't. 

It takes time for the body to re-absorb or clear dead tumor cells from a solid mass. The tumor mass could be 75% dead cells and still appear unchanged in size. Eventually the body does get to mopping it up, though.

Case 6: Male with terminal Stage 4 pancreatic cancer (October 2024)

Posted by Dave on X.com:

My dad is still alive today 2.5 years after a terminal stage 4 pancreatic cancer diagnosis thanks to MEBENDAZOLE. His pancreatic tumor has been undetectable for 2 years.

Note: Although technically mebendazole is not the same as fenbendazole, both mebendazole and fenbendazole are part of a larger group of drugs known as benzimidazole*, which are anthelmintic drugs (i.e., drugs that kill parasitic worms).

*The class of drugs known as benzimidazoles includes fenbendazole, mebendazole, albendazole and flubendazole.

 

Fenbendazole and mebendazole are similar in that they both eliminate parasitic worms, but there is a difference. Mebendazole is approved for human consumption by the FDA, while fenbendazole is only approved for veterinary use and has not been approved for human use.

Mebendazole is the form that is approved for human use while fenbendazole is approved for veterinary use. The main difference is the cost. While most of the pre-clinical research uses mebendazole, probably because it is the FDA-approved-for-humans form of fenbendazole, virtually most of the self-treating clinical reports involve the use of fenbendazole.

Case 7: Recurring Pancreatic Tumor - September 2024 (Last update)

Source: X/Twitter

Case 8: Stage 4 Pancreatic Cancer with Liver metastasis - December, 2022

I’m in Remission!! Pancan stage 4 to liver. 5 months JTP 4 months of that 5 with Chemo biweekly. Check out my scan images.(The black areas on 2nd image are my kidneys). I’m getting last chemo infusion today then going on maintenance pills. God Bless Joe Tippens, God, all the prayer warriors. Never give up yall !!

You'r welcome to share my story anywhere and everywhere. I feel I was saved so that I can be a testament to the protocol and share it as much as I can.

Case 9: Stage 4 Pancreatic Cancer - June 2024

“My Cancer Story! I was diagnosed with stage 4 pancreatic cancer in August 2023, and without treatment, I had 3-6 months to sort out my affairs.

I began my fenbendazole protocol immediately.

I nearly quit up since my quality of life had deteriorated dramatically. But I started to feel better. Less nausea. I had gained some weight back! Increased energy. My scan in November 2023 indicated that this severe cancer had neither grown or spread. My cancer marker dropped from over 100,000 to 35,000. As of January 2024, my new marker number was 18k!!! My oncologist was just scratching his head, and a family member said he seemed bewildered! And no, I did not inform him about the fenben.”

I was terrified he’d drop me as a patient. I was quite appreciative for fenben and how it has helped me. I was feeling better and stronger. I had scans and bloodwork done in March, and my markers are now down to 6000. And the tumors were shrinking!!! Two weeks after my previous scan. I scanned again, and it returned NED.

This was my protocol:

Morning

• Curcumin (600mg daily)
• Zinc (50mg)
• Milk thistle, As a food supplement, take 15 – 30 drops, 2-3 times daily in a little fruit juice or water. 7 days a week
• Serrapeptase (120,00IU)
• Fenbendazole (1000mg of Panacur C is advised to be taken seven days a week. It is recommended that it should be taken with a meal).

Night

• Curcumin (600mg tablet per day are recommended
• Berberine (600mg 2-3 times a day )
• Quercetin (500mg 1/day)
• Turkey Tail
• Vitamin E (800mg for 7 days a week)
• Fenbendazole (1000mg at night)
• Ivermectin 12mg daily 5/7days a week
• Limit sugar and processed food intake
• Drank green tea often”

*My Take…

This is an excellent protocol.

*Dr. William Makis is a Canadian physician with expertise in Radiology, Oncology and Immunology. Governor General’s Medal, University of Toronto Scholar. Author of 100+ peer-reviewed medical publications.    

**Note on pancreatic cancer marker (CA 19-9):

A CA 19-9 test measures the amount of a protein called CA 19-9 (cancer antigen 19-9) in a sample of your blood. CA 19-9 is a type of tumor marker. Tumor markers are substances made by cancer cells or by normal cells in response to cancer in your body. Healthy people can have small amounts of CA 19-9 in their blood. High levels of CA 19-9 are often a sign of pancreatic cancer. But high levels can also be a sign of other types of cancer or certain conditions that aren't cancer. For example, gallstones, pancreatitis and cirrhosis of the liver can cause high CA 19-9 levels.

The original source of this article is COVID Intel.

Case 1: Stage 4 Pancreatic Cancer (Last update: March, 2023)

My family member was diagnosed in stage 4 pancreatic cancer in August 2022. She was told it was very aggressive and without treatment she had 3-6 months and to get her affairs in order. She started 220 fenben immediately. She was very ill and hospitalized with sepsis and colitis from eating tainted peanut butter. She lost about 20 pounds. It took 2 months to start chemo, which made her very sick. We almost gave up because her quality of life had declined significantly. But she started feeling better. Less nausea. She has gained weight back! More energy.. Her latest scan showed this aggressive cancer has not grown or spread. Her cancer numbers or markers went from being over 100k down to 35k.

*** UPDATE: As of today, march 2nd, her new marker number is 18k!!) Her oncologist was just scratching his head.. my family member stated he looked confused! And no, she didn’t tell him about the fenben. We are afraid he would drop her as a patient.We are so very grateful for fenben and how it’s helped her. She is feeling better, stronger, and enjoying her family. I have never posted on here. But I wanted to give you some hope!

**UPDATE**She had scans and bloodwork done 2 weeks ago and we got the results today!! She is eating better and gaining weight.. Her markers are now down to 6000. AND THE TUMORS ARE SHRINKING!!! We are very grateful!!

Are there more? For more Fenbendazole case series in other cancer types, check out Fenbendazole Cancer Case Series.

Related: 

Potential Repurposed Therapies for Pancreatic Cancer: A Review of Emerging Approaches (2025)

Pancreatic Cancer Patient Survivor Stories (Seena Magowitz Foundation)

Repeated COVID-19 Vaccination as a Poor Prognostic Factor in Pancreatic Cancer: A Retrospective, Single-Center Cohort Study (2025)

Read More: Pancreatic Cancer series