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Showing posts from June, 2024

Fenbendazole Review by Dr David Gorski: Fenbendazole is fast becoming the laetrile of the 2020s

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Let’s start with the article that caught my attention over the weekend,  Triple-Negative Breast Cancer Eradicated by Fenbendazole , in which 2SGitW brags, “Fenbendazole kills the cancer cells responsible for killing cancer patients.” As I learned, it’s a followup to a  cancer cure testimonial published a week earlier  on the Substack in which 2SGitW massively exaggerated the the significance of some promising preclinical and lab studies suggesting that fenbendazole might have anticancer activity against triple-negative breast cancer written by someone going under the ‘nym of  BenFen , who claims to be a “retired University scientist who happened across fenbendazole when a loved one developed terminal cancer” and runs a  Substack  that publishes cancer cure testimonials due to fenbendazole. More interestingly, it turns out that fenbendazole repurposing has been a favorite “alternative cancer cure” since at least 2017, if not earlier, but the rise of ivermect...

Secretome vs Exosome: What's the Difference?

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In scientific terms, the secretome is the totality of all substances released by stem cells to the outside. These include micro-vesicles, exosomes, proteins, cytokines (cell messengers), hormone-like substances and so-called immunomodulatory substances. Based on current science, it is believed that the effect of stem cells in clinical trials conducted to date is not from the cells as such, but via the vesicles, protein molecules and other substances such as cytokines released by the cells. These substances released to the outside are called "the secretome" as an umbrella term, because the release is called secretion. Which substances of the secretome trigger the actual effects is still largely unknown. What is a Secretome? Stem cells communicate with other cells by releasing messenger substances to the outside. The totality of all released substances is called secretome (from secretion = release to the outside). The secretome can contain exosomes, micro-vesicles, proteins, gr...

List of CAR T-Cell Companies Worldwide 2024

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CAR T-cell therapy (Chimeric Antigen Receptor T-Cell) is a type of immunotherapy where doctors collect immune cells, modify them in a laboratory, and provide them the power to easily recognize and kill cancer cells. When infused into a patient, the cells get multiplied and stay in the body as “living drugs.” This article provides a comprehensive list of CAR-T therapy companies worldwide. Read on to learn more about innovative CAR-T cell therapy companies and the technologies they are using to fight cancer. Leaders of the CAR-T Cell Therapy Industry In 1987, an Israeli immunologist, Dr. Zelig Eshhar from The Weizmann Institute of Science, created the world’s first “chimeric antigen receptor” (CAR). Because CARs are engineered receptors, they do not exist in nature. Today, over one hundred companies are developing CAR-T technologies from across the globe. An Introduction to CAR-T Companies CAR T-cell therapy  is an approach that is being explored as an alternative to conventional tr...

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