12 Best Anti-Cancer Supplements for Cancer Prevention (2023): Research Review
It can be difficult to determine which dietary supplements may be beneficial
for cancer prevention or treatment, as many do not have the scientific
evidence to support the use. This article compiles more than 100 references and supporting studies related to cancer and supplements.
It's important to note that dietary supplements
are not regulated by the U.S. Food and Drug Administration (FDA) in the same
way that medications are, and the safety and effectiveness of these products
may not be fully established.

That being said, taking the right supplements with a nutritious and well-rounded diet can provide a host of added health benefits.
For example, supplements can fill in the nutritional gaps of your diet, and can even assist the body in preventing and assisting in the treatment of certain kinds of illnesses, including cancer.
Note: When interpreting scientific studies, let’s remember that cell
culture results are trumped by mouse results. Mouse results are trumped by
human results. Case studies & small human trial results are trumped by
double-blind placebo controlled ones.
Cancer and supplements
When it comes to cancer of any kind, it’s important to realize that no dietary supplement can fully treat or cure cancer, according to BreastCancer.org. However, there are some supplements that can potentially help prevent cancer or assist in your cancer recovery.
While many vitamins and minerals can benefit your general health, there’s a
huge market of unregulated supplements that may provide no added benefit to
your health. Certain supplements even have the potential to
negatively impact
cancer treatments. This is because some supplements can counteract
medications or medical therapies. If you’re thinking about supplementing
your diet with anti-cancer vitamins, always talk to your doctor first.
1. Vitamin D3, K2 and Magnesium
Vitamin D can absorb calcium and help the immune, muscle, and nervous systems function properly.A number of epidemiologic studies have investigated whether people with higher vitamin D intakes or higher blood levels of vitamin D have lower risks of specific cancers. The results of these studies have been inconsistent, possibly because of the challenges in carrying out such studies. For example, dietary studies do not account for vitamin D made in the skin from sunlight exposure, and the level of vitamin D measured in the blood at a single point in time (as in most studies) may not reflect a person’s true vitamin D status. Also, it is possible that people with higher vitamin D intakes or blood levels are more likely to have other healthy behaviors. It may be one of these other behaviors, rather than vitamin D intake, that influences cancer risk.
Several randomized trials of vitamin D intake have been carried out, but these were designed to assess bone health or other non-cancer outcomes. Although some of these trials have yielded information on cancer incidence and mortality, the results need to be confirmed by additional research because the trials were not designed to study cancer specifically.
The cancers for which the most human data are available are colorectal, breast, prostate, and pancreatic cancer. Numerous epidemiologic studies have shown that higher intake or blood levels of vitamin D are associated with a reduced risk of colorectal cancer (R). In contrast, the Women’s Health Initiative randomized trial found that healthy women who took vitamin D and calcium supplements for an average of 7 years did not have a reduced incidence of colorectal cancer (NEJM 2006). Some scientists have pointed out that the relatively low level of vitamin D supplementation (10 μg, or 400 IU, once a day), the ability of participants to take additional vitamin D on their own, and the short duration of participant follow-up in this trial might explain why no reduction in colorectal cancer risk was found.
Several randomized trials of vitamin D intake have been carried out, but these were designed to assess bone health or other non-cancer outcomes. Although some of these trials have yielded information on cancer incidence and mortality, the results need to be confirmed by additional research because the trials were not designed to study cancer specifically.
The cancers for which the most human data are available are colorectal, breast, prostate, and pancreatic cancer. Numerous epidemiologic studies have shown that higher intake or blood levels of vitamin D are associated with a reduced risk of colorectal cancer (R). In contrast, the Women’s Health Initiative randomized trial found that healthy women who took vitamin D and calcium supplements for an average of 7 years did not have a reduced incidence of colorectal cancer (NEJM 2006). Some scientists have pointed out that the relatively low level of vitamin D supplementation (10 μg, or 400 IU, once a day), the ability of participants to take additional vitamin D on their own, and the short duration of participant follow-up in this trial might explain why no reduction in colorectal cancer risk was found.
According to BreastCancer.org, research suggests that certain cancers such as breast cancer, can have a higher risk of occurring when the body has low levels of vitamin D.
Studies also show a link between vitamin D deficiency and cardiovascular disease, diabetes, and cancer (Sizar, 2020).
In 2016, a landmark study published in PLOS ONE found that women over 55 with blood concentrations of vitamin D higher than 40 ng/ml, had a 67% lower risk of cancer compared women with levels lower than 20 ng/ml.
The recommended daily amount of vitamin D is 15 mcg. Vitamin D can be absorbed through sunlight, or with the following diet:
- fatty fish
- egg yolks
- fortified milk
Make sure to take 500 mg to 1000 mg of magnesium and 150 mcg of vitamin K2, (not K1) which are important cofactors for optimizing vitamin D function. And, remember the only way you know what your vitamin D level is, is to test it. Vitamin D level should be in a therapeutic range of 50 to 70 ng/ml for treatment of rheumatoid arthritis. Most people are shocked how low their level is when they finally get around to testing it.
Furthermore, it is still uncertain if vitamin D alone will be effective for all cancers, and the reason for cancer patients’ ailments vary from one to another.
2. Omega-3 Fatty Acids
Most people use fish oil supplements to enhance the amount of omega-3’s in their diet.Findings from a study performed in mice, research from Harvard Medical School’s Beth Israel Deaconess Medical Center in Boston demonstrated omega-3 fat could reduce tumor growth by 67% (R).
The research was presented April 4, 2022 at the annual Experimental Biology meeting in Philadelphia. The animal model showed that omega-3 fatty acids helped promote the cancer-fighting activities of immunotherapy and anti-inflammatory therapy.
Many governments recommend eating omega-3 containing fatty fish, two times
per week. But that is often not enough. Ideally, people would need to eat
fatty fish four times per week, while also supplementing with omega-3 fatty
acids, at least 1,000 mg of pure omega-3 (DHA and EPA) per day.
However, fish oil was shown in one study on mice (2015) to possibly reduce the effectiveness of chemotherapy, and for that
reason ground flax seed is a worthy alternative.
Make sure you buy high-quality omega-3 fatty acid supplements, meaning that the omega-3 fatty acids are pure and have not oxidized much (having low “TOTOX” value).
Related: Researchers Showed Omega-3 Could Cut Tumor Growth by 67%
3. Green tea (EGCG)
Several
in vitro, in vivo, and epidemiological studies
have reported that the consumption of green tea may decrease cancer
risk. Studies have also confirmed numerous health benefits of green tea including
prevention of cancer (R, R) and cardiovascular disease, as well as anti-inflammatory, antioxidant,
antiarthritic, antibacterial, and antiviral effects. (R, R, R, R).
Green tea also contains chemicals called polyphenols that have antioxidant
and anti-inflammatory properties.
The Minnesota Green Tea Trial (MGTT. 2015) is the largest and longest double-blind,
placebo-controlled, randomized intervention study that specifically
evaluated the effects of oral GTE (green tea extract) containing defined
quantities of EGCG on established biomarkers of breast cancer risk.
They randomized and stratified 1075 healthy postmenopausal women at
high risk of breast cancer according to their breast tissue density
and catechol-O-methyltransferase genotypes and divided them into two
groups: 537 placebo and 538 green tea groups. Green tea group
participants took 4 capsules that contained 843 mg EGCG, whereas the
placebo group took capsules without green tea extracts.
Researchers measured changes in percent mammographic density,
circulating endogenous sex hormones, and proteins of the insulin-like
growth factor axis. Their results showed that supplementation
with green tea extract could modify and reduce mammographic density
(MD) and protect against breast cancer, even though it was only
significant in younger women (50–55 years) and had no effect in older
women (R), an age-dependent effect similar to those of tamoxifen.
If you have cancer, consider drinking up to 3 cups of green tea per day to
experience the benefits. Green tea pills are also available, but may be
too concentrated.
4. Garlic
Garlic is a great choice when it comes to giving your body a little extra protection. To reap the benefits of garlic, you should eat one clove per day, or- antibacterial properties
- blocking and halting the activation of cancer-causing substances
- enhanced DNA repair
- a reduction in cancer cells spreading
The active component in garlic is allicin, a compound that has
been shown to kill off cancer cells in multiple test-tube studies
(Source, Source, Source).
There is evidence demonstrating garlic can kill cancer cells in vitro. Several studies have analyzed the effects that dietary garlic may have on the development of colorectal cancer.
Several clinical studies have found an association between garlic intake and a lower risk of certain types of cancer.
One study of 543,220 participants found that those who ate lots of Allium vegetables, such as garlic, onions, leeks and shallots, had a lower risk of stomach cancer than those who rarely consumed them (Source).
A study of 471 men showed that a higher intake of garlic was associated with a reduced risk of prostate cancer (Source).
A meta-analysis of 11 studies, published in January 2020, did find evidence that garlic could reduce the risk of ColoRectal Cancer.
Another study published in the Asia Pacific Journal of Clinical Oncology (2019) revealed the odds of getting ColoRectal Cancer were 79% lower in those who a diet high in allium vegetables, which include garlic, leeks and onions.
Based on these findings, including 2–5 grams (approximately one clove) of fresh garlic into your diet per day can help you take advantage of its health-promoting properties.
Despite the promising results showing an association between garlic and a reduced risk of cancer, more studies are needed to examine whether other factors play a role.
Despite the promising results showing an association between garlic and a reduced risk of cancer, more studies are needed to examine whether other factors play a role.
5. Turmeric / Curcumin
The spice turmeric can be extremely helpful when it comes to fighting cancer. Studies show that the curcumin in turmeric may kill cancer cells and slow tumor growth. This preclinical research has taken curcumin from the lab to the clinic.The benefits of curcumin may include:
- blocking cancer cells from multiplying
- killing colon, breast, prostate, and melanoma cancer cells
- slowing tumor growth
In 2023, there are
more than 50 clinical trials
with curcumin, most of which are still ongoing.
Curcumin has also been identified as one of the most powerful
chemopreventive and anticancer agents, and recognized for its wide spectrum
of pharmacological properties and inhibitory effects on metabolic enzymes,
according to
PubChem, which notes its wound healing and antimicrobial effects, and states:
"Curcumin blocks the formation of reactive-oxygen species, possesses anti-inflammatory properties as a result of inhibition of cyclooxygenases (COX) and other enzymes involved in inflammation; and disrupts cell signal transduction by various mechanisms including inhibition of protein kinase C.
These effects may play a role in the agent's observed antineoplastic properties, which include inhibition of tumor cell proliferation and suppression of chemically induced carcinogenesis and tumor growth in animal models of cancer."
"Curcumin blocks the formation of reactive-oxygen species, possesses anti-inflammatory properties as a result of inhibition of cyclooxygenases (COX) and other enzymes involved in inflammation; and disrupts cell signal transduction by various mechanisms including inhibition of protein kinase C.
These effects may play a role in the agent's observed antineoplastic properties, which include inhibition of tumor cell proliferation and suppression of chemically induced carcinogenesis and tumor growth in animal models of cancer."
Another
study (2013)
showed curcumin as able to suppress cancer proliferation and apoptosis
(programmed cell death), thereby acting as a chemopreventive agent in skin, colon and stomach
cancers. Other studies using animal models list breast, bladder, brain,
esophageal, kidney, liver, lung, pancreas and prostate cancers, and
more.
Because it's not easily absorbed through your gastrointestinal tract, it's
more effective to use a high-quality bioavailable curcumin extract,
according to a
2013 study. A typical anticancer dose is just under 1 teaspoon of curcumin extract
three or four times daily.
Both curcuminoids and related turmeric products have been sanctioned by the U.S. Food and Drug Administration (FDA) as safe.
6. Molecular Hydrogen

1975 - Although hydrogen gas was studied as a
therapy in a skin squamous carcinoma mouse model back in 1975
(Science. 1975), its potential in medical application has not been vastly
explored.
2007 - Oshawa et al. reported that hydrogen
could ameliorate cerebral ischemia-reperfusion injury by
selectively reducing cytotoxic reactive oxygen species (ROS),
including hydroxyl radical (•OH) and peroxynitrite (ONOO-) [Nat Med. 2007], which then provoked a worldwide attention.
2008 -
In human cancer cells, hydrogen water suppressed tumor growth by
reducing oxidative stress (Oncol Res. 2008). Hydrogen water also blocked the creation of new blood
vessels in human lung cancer cells, preventing cancer from
spreading and growing [Biol Pharm Bull. 2008].
2010 - Hydrogen water combined with increased temperature
(hyperthermia) had a strong cancer-killing effect in cells [Oncol Rep. 2010].
2011 - A study of 49 patients (published in 2011) on radiation
therapy for liver cancer, drinking hydrogen water (1.5 – 2
L/day) improved the patients’ quality of life and appetite.
Hydrogen water could reduce oxidative stress and damage from
radiation without compromising its cancer-killing effects [R].
2015 - In a lab study published in 2015 (PeerJ. 2015), hydrogen water administration improved the survival of mice
with colon 26-induced cancer. Furthermore, hydrogen water
enhanced cell death in cancer cells. Hydrogen water also
increased the inhibitory effect of 5-FU on colon 26 cells.
Additionally, high-content hydrogen water exhibited stronger
anti-oxidative and anticancer activity than did the natural
hydrogen water.
2017 - A study (published in
the Molecular and Clinical Oncology), evaluated the protective
effect of hydrogen-rich water on liver function of colorectal
cancer patients treated with chemotherapy in 152 patients. The
hydrogen-rich water group exhibited protective effect against
the chemotherapy related liver injury [R].
2019 - The first case report of hydrogen inhalation therapy in a
patient with metastatic Gall Bladder Cancer was published by a
team in China. The patient has gradually improved and has survived
for more than 10 months (Onco Targets Ther. 2019).
In a review paper on hydrogen gas and cancer
treatment, it was suggested that hydrogen gas may work alone or
synergistically with other therapy to suppress tumor growth (Front Oncol. 2019).
In Japan, patients with stage IV colorectal cancer inhaled H2 gas
for 3 h/day in their own homes and received chemotherapy. H2 gas
improved progression-free survival and overall survival times (Oncol Rep. 2019).
In China, 82 patients with stage III and IV cancer (advanced
cancer) were prospectively followed-up, after treatment with
Hydrogen (H2) inhalation. No severe blood toxicity was observed.
H2 Inhalation of H2 gas induced complete and partial remission in
tumors of the 80 patients (Med Gas Res. 2019). Most of the cancer types are mainly solid tumors with 19
non-small cell lung cancer, 16 gynecological cancer, 11
hepato-cellular cancer, 10 breast cancer, 6 gastrointestinal
cancer, 6 urological cancer and 8 other types of advanced
cancer.
2020 - An updated review was published in 2020 (Med Gas Res. 2020).
One clinical trial (NCT03818347) is now on-going to study hydrogen gas in cancer
rehabilitation for multiple cancer types in China. 2
publications that are associated with this research data
have been
published.
The first publication
(Ann Palliat Med. 2019) was case reports of 3 nasopharyngeal cancer (NPC)
patients with radiotherapy-induced hearing loss. This is the
first study to show that, after treatment for nasopharyngeal
carcinoma, hearing loss can be reduced using hydrogen-oxygen
therapy.
The second publication (Med Gas Res. 2020), 58 patients with advanced non-small lung cancer were
enrolled into 5 groups:
1) refused drug treatment (control group)
2) refused drug treatment (hydrogen therapy only)
3) H2 + chemotherapy,
4) H2 + targeted therapy, and
5) H2 + immunotherapy group.
After 16 months of follow-up, progression-free survival of
the control group was lower than that of the H2-only group, and
significantly lower than that of H2 + chemotherapy, H2 + targeted
therapy, and H2 + immunotherapy groups.

1975 - Although hydrogen gas was studied as a therapy in a skin squamous carcinoma mouse model back in 1975 (Science. 1975), its potential in medical application has not been vastly explored.
2007 - Oshawa et al. reported that hydrogen could ameliorate cerebral ischemia-reperfusion injury by selectively reducing cytotoxic reactive oxygen species (ROS), including hydroxyl radical (•OH) and peroxynitrite (ONOO-) [Nat Med. 2007], which then provoked a worldwide attention.
2008 - In human cancer cells, hydrogen water suppressed tumor growth by reducing oxidative stress (Oncol Res. 2008). Hydrogen water also blocked the creation of new blood vessels in human lung cancer cells, preventing cancer from spreading and growing [Biol Pharm Bull. 2008].
2010 - Hydrogen water combined with increased temperature (hyperthermia) had a strong cancer-killing effect in cells [Oncol Rep. 2010].
2011 - A study of 49 patients (published in 2011) on radiation
therapy for liver cancer, drinking hydrogen water (1.5 – 2
L/day) improved the patients’ quality of life and appetite.
Hydrogen water could reduce oxidative stress and damage from
radiation without compromising its cancer-killing effects [R].
2017 - A study (published in the Molecular and Clinical Oncology), evaluated the protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with chemotherapy in 152 patients. The hydrogen-rich water group exhibited protective effect against the chemotherapy related liver injury [R].
In a review paper on hydrogen gas and cancer treatment, it was suggested that hydrogen gas may work alone or synergistically with other therapy to suppress tumor growth (Front Oncol. 2019).
In Japan, patients with stage IV colorectal cancer inhaled H2 gas
for 3 h/day in their own homes and received chemotherapy. H2 gas
improved progression-free survival and overall survival times (Oncol Rep. 2019).
In China, 82 patients with stage III and IV cancer (advanced
cancer) were prospectively followed-up, after treatment with
Hydrogen (H2) inhalation. No severe blood toxicity was observed.
H2 Inhalation of H2 gas induced complete and partial remission in
tumors of the 80 patients (Med Gas Res. 2019). Most of the cancer types are mainly solid tumors with 19
non-small cell lung cancer, 16 gynecological cancer, 11
hepato-cellular cancer, 10 breast cancer, 6 gastrointestinal
cancer, 6 urological cancer and 8 other types of advanced
cancer.
2020 - An updated review was published in 2020 (Med Gas Res. 2020).
The second publication (Med Gas Res. 2020), 58 patients with advanced non-small lung cancer were
enrolled into 5 groups:
After 16 months of follow-up, progression-free survival of the control group was lower than that of the H2-only group, and significantly lower than that of H2 + chemotherapy, H2 + targeted therapy, and H2 + immunotherapy groups.
One clinical trial (NCT03818347) is now on-going to study hydrogen gas in cancer
rehabilitation for multiple cancer types in China. 2
publications that are associated with this research data
have been
published.
The first publication (Ann Palliat Med. 2019) was case reports of 3 nasopharyngeal cancer (NPC) patients with radiotherapy-induced hearing loss. This is the first study to show that, after treatment for nasopharyngeal carcinoma, hearing loss can be reduced using hydrogen-oxygen therapy.
published.
The first publication (Ann Palliat Med. 2019) was case reports of 3 nasopharyngeal cancer (NPC) patients with radiotherapy-induced hearing loss. This is the first study to show that, after treatment for nasopharyngeal carcinoma, hearing loss can be reduced using hydrogen-oxygen therapy.
1) refused drug treatment (control group)
2) refused drug treatment (hydrogen therapy only)
3) H2 + chemotherapy,
4) H2 + targeted therapy, and
5) H2 + immunotherapy group.
After 16 months of follow-up, progression-free survival of the control group was lower than that of the H2-only group, and significantly lower than that of H2 + chemotherapy, H2 + targeted therapy, and H2 + immunotherapy groups.
7. Quercetin
Quercetin is an antioxidant flavonol that's found in foods such as red grapes, green tea, elderflower and onions, to name a few. As the health benefits of the supplement become more widely known, the market has grown rapidly (R). According to market research, quercetin market was worth $261.12 million in 2020 and is expected to reach $406.58 million in 2027.2022 - A paper published in August 2022 in Nutrition Research analyzed the pro-apoptotic effect that quercetin has on aging cells. The paper reviewed preclinical and early phase data using quercetin as a senolytic agent and found the data showed it was effective in “preventing or alleviating cancer formation.”
The authors reviewed the importance of cellular aging in the development of cancer cells and the effect that quercetin may have on the suppression of cancer cell proliferation.
Cellular senescence is a dynamic and multi-step process that is associated with alterations in metabolic activity and gene expression. This can compromise tissue regeneration and contribute to aging. On the other hand, by removing senescent cells, age-related dysfunction can be attenuated and potentially extend the lifespan.
2020 - Another paper (2020) identified some of the anti-inflammatory, antioxidant
and antiproliferative properties quercetin has that enhances breast cancer
treatment, while another (2020) evaluated its effect on the treatment of ovarian
cancer, which is a serious cancer growth and threat to women's health.
2019 - Research also has demonstrated that quercetin can promote the loss of cell
viability and autophagy through several pathways, including those
involving mitochondrial function and glucose metabolism.
This study published in 2017 in Oncology Reports took things a step further, finding that quercetin induced cancer cell death in nine types of cancer, including prostate cancer, colon cancer, and breast caner.
In another 2017 study, researchers gave quercetin to mice with tumors. Researchers found that mice in the quercetin-treated group showed delayed tumor growth, no significant changes in daily behavior, significantly better survival ratings, and increased rates of cell death.
This study published in 2017 in Oncology Reports took things a step further, finding that quercetin induced cancer cell death in nine types of cancer, including prostate cancer, colon cancer, and breast caner.
In another 2017 study, researchers gave quercetin to mice with tumors. Researchers found that mice in the quercetin-treated group showed delayed tumor growth, no significant changes in daily behavior, significantly better survival ratings, and increased rates of cell death.
Quercetin may also target bladder cancer. In 2016, researchers published a landmark study in the American Journal of
Cancer Research. Researchers analyzed quercetin’s effect on cancer cells
in a test tube. They concluded, “We are the first to show that quercetin
displays potent inhibition on bladder cancer cells via activation of AMPK
pathway.”
In 2015, researchers reviewed available test tube and animal studies on quercetin and prostate
cancer. After reviewing available evidence, researchers found that
quercetin suppressed cell growth and induced cell death in prostate cancer
cells.
Lab studies (2011) have also demonstrated that quercetin is a strong antioxidant and has pro-apoptotic effects on tumor cells, with the ability to block growth at different phases of the cell cycle.
Lab studies (2011) have also demonstrated that quercetin is a strong antioxidant and has pro-apoptotic effects on tumor cells, with the ability to block growth at different phases of the cell cycle.
Data (2015) indicate that quercetin could play a role in cancer
treatment as it reportedly has synergistic effects in combination with
chemotherapy agents or radiation therapy. Quercetin has also shown
promising results with chemoprotective and radioprotective properties, by
protecting normal cells against the effects of chemotherapy and radiation
therapy.
According to Mount Sinai, quercetin should be used with caution as it may interact with certain
antibiotics by reducing the effectiveness of the drug. It may also enhance
the effect of some blood thinners, which can increase your risk of
bleeding. In addition to these, it may interact with corticosteroids,
digoxin, cyclosporine and fluoroquinolones.
Early research on the cancer-fighting benefits of quercetin is promising,
although more research needs to be performed to verify these effects in
humans.
8. Melatonin
Melatonin is one of the most important antioxidant molecules. In the human body — aside from having direct antioxidant effects — it also stimulates the synthesis of glutathione and other important antioxidants like superoxide dismutase and catalase.
Many people are not aware that only 5% of your body’s melatonin — which is
also a potent anticancer agent — is produced in your pineal gland. The
other 95% is produced inside your mitochondria — provided you get
sufficient near infrared exposure which is typically from sun on your bare
skin. This is why vitamin D is more than likely a biomarker for sun
exposure, which is intricately involved in melatonin production. (R)
A case series of 14 advanced cancer patients (Trends in Oncology 2020), treated with high dose (1,000 mg/day) of melatonin; achieved a disease
control of 54% of the patients.
The authors also concluded that:
"Moreover, this preliminary study may also suggest that high dose
melatonin has no toxicity in cancer patients with poor clinical status, as
well as in healthy subjects."
Vitamin C is known as an antioxidant, but at high concentrations, vitamin
C can kill cancer cells through a pro-oxidant property (Transl Oncol. 2020). This study has also demonstrated that vitamin C treatment with
magnesium supplementation provided more effective anticancer therapy than
vitamin C treatment alone.
High-dose vitamin C cancer therapy was introduced by Linus Pauling and
Ewan Cameron [R]. Clinical demonstration results by Pauling and Cameron showed that
intravenous injection of 10 g/day of vitamin C extended the survival time
of terminal cancer patients by about 4.2 times. However, results from the
Mayo Clinic in 1979 showed that the survival time of vitamin C–treated
patients was even shorter than that of the placebo group patients [R]. A significant difference between those two research groups was the
route of AA administration: intravenous injection and oral administration,
respectively.
The best way to prevent cancer is by maintaining good health, like from
eating a nutritious whole-food diet with lots of fruits and vegetables,
and a healthy lifestyle. While there’s no silver bullet supplement,
there are some anti-cancer supplements on the market that may help you
keep the disease at bay or stop it from getting worse. Whether you’re
living with cancer, a survivor, or just concerned for your health, talk
to your doctor to determine the best treatment for you.
@briomedical Melatonin pro-oxidative effects can provide cancer patients with an additional layer of support during conventional, alternative and holistic treatments. Melatonin is a hormone that helps regulate the body’s circadian rhythm and sleep-wake cycle, but it also has powerful antioxidant and anti-inflammatory effects. In cancer patients, melatonin can help fight oxidative stress, which can help reduce cancer tumor growth and improve the body’s response to anti-cancer treatments. Furthermore, melatonin can help protect healthy cells from damage caused by radiation and chemotherapy, while also increasing the body’s overall immunity and energy levels. By providing cancer patients with an extra layer of protection against the damaging effects of cancer treatments, melatonin pro-oxidative effects can be an invaluable tool in the fight against cancer. @briomedical #melatonin #melatoninsupplement #cancer #integrativemedicine #alternativetreatment #cancercare #research #science #carcinogen ♬ Storytelling - Adriel
9 - 10. Vitamin C and B6
Obese women who took vitamin C and B6 at amounts that exceeded the
recommended daily intake levels were associated with a lower risk of
breast cancer, according to a five-year long South Korean cohort study. 40,432 women without a history of cancer at baseline were included in
this study.
To understand the mechanism of AA's anticancer activity, many research
groups have treated colon, prostate, leukemia, lymphoma, brain, and
stomach cancer cells and chemically or genetically transformed cancer
cells with AA and showed cancer growth inhibition and even cancer cell
death through hydrogen peroxide–mediated reactive oxygen species (ROS)
generation [R]. In most cases, the pharmacological concentration of vitamin C required
for anticancer effects (EC50 value of 1–10 mM) could only be achieved by
intravenous administration. Thus, to apply vitamin C as an anticancer
therapy, a high intracellular concentration in cancer cells is critically
important (R).
Sally Norton, author of “Toxic Superfoods: How Oxalate Overload Is Making You Sick — and How to Get Better,” explains:
For these reasons, if you take vitamin C on a regular basis, Norton recommends limiting it to 250 mg a day. This is enough to meet your nutritional requirements and is unlikely to cause oxalic acid-related trouble. The exception would be if you are septic, in which case large doses of IV ascorbic acid can save your life.
The Hazards of Excessive Vitamin C
Vitamin C and ascorbic acid can lead to problems if your body is
already loaded with oxalates as it is metabolically reduced to
oxalic acid during breakdown.
Sally Norton, author of “Toxic Superfoods: How Oxalate Overload Is Making You Sick — and How to Get Better,” explains:
“The major source of internal oxalate is ascorbic acid or vitamin
C ... There are lots of case studies of train wrecks from
supplements, and lots of case studies about problems with
intravenous vitamin C. Let me tell you my personal story. I had
vitamin C chelation ... I didn't know I had an oxalate problem
...
By the third time, I became harder and harder to stab for the IV needle because now my veins were ropier and rollier and would run away from the needle. That's fibrosis ... I only had IV vitamin C maybe 10 times. But the doctor and the nurse took no notice of this side effect of the treatment — that I was becoming more fibrotic and harder to puncture ...
It's hubris to say, ‘Oh, well, it's fine. All my patients are doing great on my vitamin C IVs when you're not open to seeing the side effects. One of the studies demonstrated that just with oral supplementation, for not all that long, once they stopped the vitamin C, the level of oxalate in the urine went way up.
So, while the body's being assaulted by too much vitamin C, it's busy sequestering the oxalate that's forming and holding onto it and protecting the kidneys from devastation, from excessive oxalate load. Once you stop producing or eating too much oxalate, this holding pattern can let go, and now you see much higher oxalate levels in the blood and the urine.”
By the third time, I became harder and harder to stab for the IV needle because now my veins were ropier and rollier and would run away from the needle. That's fibrosis ... I only had IV vitamin C maybe 10 times. But the doctor and the nurse took no notice of this side effect of the treatment — that I was becoming more fibrotic and harder to puncture ...
It's hubris to say, ‘Oh, well, it's fine. All my patients are doing great on my vitamin C IVs when you're not open to seeing the side effects. One of the studies demonstrated that just with oral supplementation, for not all that long, once they stopped the vitamin C, the level of oxalate in the urine went way up.
So, while the body's being assaulted by too much vitamin C, it's busy sequestering the oxalate that's forming and holding onto it and protecting the kidneys from devastation, from excessive oxalate load. Once you stop producing or eating too much oxalate, this holding pattern can let go, and now you see much higher oxalate levels in the blood and the urine.”
For these reasons, if you take vitamin C on a regular basis, Norton recommends limiting it to 250 mg a day. This is enough to meet your nutritional requirements and is unlikely to cause oxalic acid-related trouble. The exception would be if you are septic, in which case large doses of IV ascorbic acid can save your life.
11. Resveratrol and Pterostilbene
Resveratrol is a polyphenol in grapes, berries, peanuts, and red wine
that may promote longevity by activating certain genes called
sirtuins. It has been shown to increase the lifespan of fruit flies,
yeasts, and nematodes (Source).
It displays powerful antioxidant, anti-inflammatory, and anti cancer
properties in clinical trials. Resveratrol also enhances sirtuin
function (R).
Some of the biggest hurdles for reaping the benefits of resveratrol in
humans appear to be its limited bioavailability and rapid elimination
from the body. But those hurdles might be overcome by a compound that
has more recently gained some notice i.e. pterostilbene, with a slight
difference in molecular structure.
PubMed has indexed more than 12,000 research studies on resveratrol,
but only 500 on pterostilbene. However, the sheer number of scientific
studies on a compound doesn’t necessarily mean the compound is
superior. It’s also important to note that pterostilbene research lags
about 10 years behind resveratrol research.
The slight difference in molecular structure between resveratrol and pterostilbene provides a sound rationale for the superiority of pterostilbene. Pterostilbene should be more stable and bioavailable in theory, and preclinical studies so far validate the assumption.
The slight difference in molecular structure between resveratrol and pterostilbene provides a sound rationale for the superiority of pterostilbene. Pterostilbene should be more stable and bioavailable in theory, and preclinical studies so far validate the assumption.
12. Vitamin E
Vitamin E is an excellent cancer-fighting nutrient. Vitamin E is fat-soluble and acts as a strong antioxidant, helping the body remove cell-damaging free radicals.
Vitamin E can significantly decrease the risk for prostate, colon, and lung cancers. In fact, low amounts of
vitamin E may increase the risk of cancer. It’s important to get enough
of this vitamin daily from diet or supplements. The recommended daily
amount of vitamin E is 8 to 10 mg. You can also eat the following foods
to supplement vitamin E in your diet for example avocado, broccoli,
beans, mango and olive oil.
Precautionary note: Please do not take dosages that exceed recommended
daily intake without the guidance of a trusted medical provider.
Outlook
When interpreting scientific studies, let’s remember that cell culture
results are trumped by mouse results. Mouse results are trumped by
human results. Case studies & small human trial results are
trumped by double-blind placebo controlled ones.
This article is part of the diet and cancer series. Other diet and
cancer related articles:
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