Fenbendazole and Ivermectin in Kidney-Urinary Cancers: 2021 Stanford University Case Series and More (27 Case Reports) (December 2025)

Introduction

What is the "Stanford Fenbendazole Protocol"?

I bet you've never heard of the "Stanford Fenbendazole Protocol" for treating Cancer. Yet, it exists. But it's heavily suppressed by search engines and mainstream Oncology, especially in the United States and Canada. In 2021 a group at Stanford University Medical Center, Department of Medicine, published a Case Series (Clin. Oncol. Case Rep 2021)* on a "forbidden" repurposed drug, Fenbendazole.

*Note: Clinical Oncology Case Reports is a peer-reviewed International clinical and medical oncology and cancer research Journal. Clinical Oncology Case Reports (COCR) is a high-impact multidisciplinary journal focus on the area of clinical and medical investigation.


They wrote about 3 cases of Stage 4 Cancer patients who self-treated and cured their cancers.
 
Case 1: 63 year old man with a Stage 4 Renal Cell Carcinoma (clear cell), a 5.3cm mass and mets to pancreas and bone, failed 3 lines of chemo. He achieved remission on 1000mg Fenbendazole 3 times per week and his tumors shrank dramatically. Case 2: 72 year old man with Stage 4 Urothelial Carcinoma of Urethra, developed lung, lymph node and brain metastases. He failed radiotherapy, carboplatin, paclitaxel, pembrolizumab, and 6 cycles of gemcitabine and cisplatin Started 1000mg Fenbendazole orally 3 days per week, Vitamin E 800mg daily, Curcumin 600mg daily and CBD Oil CT scan showed tumor shrinkage of 2cm aortocaval node metastasis until it disappeared (complete radiographic response). Case 3: 63 year old woman with Stage 4 Urothelial Carcinoma of Bladder, with a 7.5cm tumor and extension to pelvic side wall. She took combination of Chemotherapy WITH Fenbendazole 1000mg three times a week. Follow-up CT revealed no evidence of disease. Sources and References:
For more Fenbendazole in Genito-Urinary stage 4 cancer case series, check out the case reports below. 

Ivermectin and Fenbendazole Kidney Cancer Success Stories (15 cases)

Case No. 15 - 2025: 81 year old California man with Stage 4 Renal Cell Carcinoma metastatic to skin, lungs, adrenal (Kidney cancer)

Dr. William Makis shared on X.com in December 2025:

IVERMECTIN, MEBENDAZOLE, CBD Oil Testimonial - 81 year old California man with Stage 4 Renal Cell Carcinoma metastatic to skin, lungs, adrenal, reports after 3 months - all tumors shrinking.

Warning: Ivermectin is so "dangerous", a lovely 81 year old California man with an 11cm kidney tumor took it with no issues - and now all his tumors are shrinking! STORY: 81 year old California man with Stage 4 Renal Cell Cancer (11cm tumor) with extensive metastases Since Mid-August 2025 he has been taking:
  • Ivermectin 75mg/day
  • Mebendazole 750mg/day
  • CBD Oil 100mg/day
Results after 3 months: All tumors are shrinking Kidney tumor 112x70x95mm shrunk to 99x60x90mm with more extensive necrosis Adrenal metastasis SUV 6.0 down to SUV 3.8 RLL Lung metastasis 38x34x32mm SUV 13 to 37x29x34mm SUV 5.3 Subpleural metastases 8mm and 4mm = 100% resolved. ========== There are several ways most Radiologists describe tumors shrinking and cancer cell killing: 1. Decreased size of tumor. 2. Decreased SUV (metabolic activity) of tumor (50% decrease in SUV suggests 50% of the cancer cells are now dead).
3. Increased necrosis (dead cancer tissue areas, often liquified). 

Ivermectin and Mebendazole are perfectly safe for an 81 year old with a 11.2cm tumor mass in his kidney (shocking, isn't it?). And no, he's not a horse. Or a cow.

Case No. 14 - 2025: 86 year old Oregon man with Stage 2 Renal Cell Carcinoma (Kidney cancer)

Dr. William Makis shared on X.com in November 2025:

IVERMECTIN and MEBENDAZOLE Testimonial: 86 year old Oregon man with Stage 2 Renal Cell Carcinoma reports after 3 months
There is NO AGE LIMIT for cancer patients getting help from repurposed drugs! STORY: 86 year old Oregon man with Stage 2 Renal Cell Carcinoma For 3 months he took: Ivermectin 100mg/day Mebendazole 1000mg/day Result: Kidney tumor shrunk from 2.7x1.5cm to 2.7x0.9cm (64% tumor volume reduction according to Grok). "There is no enhancement" From patient's family: "doctor is very satisfied and plans on checking with XXX (patient) in another year with a new MRI" From clueless Oncologist: "Great News. No concern for tumor recurrence on MRI. Let's plan for another MRI in a year."


Case No. 13 - 2025: 42 year old Saudi Arabian woman with Stage 4 Renal Cell (Kidney) Cancer

Dr. William Makis shared on X.com in October 2025:

IVERMECTIN and MEBENDAZOLE Testimonial - 42 year old Saudi Arabian woman with Stage 4 Renal Cell Carcinoma sees improvement after 2 months!
I was very happy to learn recently that I shocked an Oncologist at the King Faisal Specialist Hospital in Saudi Arabia! STORY: 42 year old Saudi Arabian woman with Stage 4 Renal Cell Carcinoma metastatic to the lungs On July 9 she started: Ivermectin 1.5mg/kg/day Mebendazole 1500mg/day After only 2 months her lung metastases are shrinking and her kidney tumor is dying (turning necrotic). "The CT showed amazing improvement" "You are our hero and you made my day. My Oncologist was speechless."


Case No. 12 - 2025: 58 year old California CEO with Stage 4 Kidney Cancer recurrence and extensive metastatic disease

Dr. William Makis shared on X.com in September 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 58 year old California CEO with Stage 4 Kidney Cancer recurrence and extensive metastatic disease shows dying tumors after 10 weeks! Yes, I have several CEOs who have come to me for help. A few famous names as well. 58 year old California CEO with Stage 4 Kidney Cancer recurrence and extensive metastatic disease (had partial nephrectomy in 2010 but cancer returned and started spreading exponentially from Dec.2024) From mid April, 2025 he started taking Ivermectin and Fenbendazole. Results are after 2.5 months or 10 weeks, with all tumors showing various degrees of dying off.


Case 11 - 2025: 68 year old North Carolina man with Stage 4 Renal Cell Clear Cell Carcinoma*

*Note: Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer, where cancer cells appear clear or pale under a microscope and originate from the kidney's filtering tubules.

Dr. William Makis shared on X.com in September 2025:

IVERMECTIN and MEBENDAZOLE Testimonial - 68 year old North Carolina man with Stage 4 Renal Cell Clear Cell Carcinoma - Cancer Free after 9 months! Oncologists have very poor success record with Kidney cancers. I think we do much better! This is one of my early successes. 68 year old North Carolina man with Stage 4 Renal Cell Clear Cell Carcinoma We got to work back in November 2024
  • Ivermectin
  • Mebendazole
9 months later: "CT Scan reveals suspected lung metastases faded away". Oncologist confirms that I am cured of kidney cancer" "THANK YOU so much for all that you have done for me and others. Your one of the very few honest doctors out there that cares".


Case No. 10 - 2025: 75 year old Southern Florida man with Stage 4 Renal Cell Carcinoma

Dr. William Makis shared on X.com in August 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 75 year old Southern Florida man with Stage 4 Renal Cell Carcinoma sees dramatic improvement after 6 months. He started low doses initially but with some research and peer review based guidance, increased those to more appropriate levels for Cancer. After 6 months on high doses of Ivermectin and Fenbendazole (in combination with Keytruda): - Lung metastasis shrunk from 14cm to 4cm - stomach metastases disappeared "Thank you for your advice and your work with our global community in fighting cancer. God Bless!"


Case No. 9 - 2025: 42 year old woman with Stage 4 Kidney Cancer to lungs, liver and shoulder

Dr. William Makis shared on X.com in August 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 42 year old woman with Stage 4 Kidney Cancer to lungs, liver and shoulder, is CANCER FREE after one year! STORY: 42 year old woman with Stage 4 Kidney Cancer to lungs, liver and shoulder Started Ivermectin and Fenbendazole Reports back after 1 year: "my scan today showed NED (No Evidence of Disease)." "I cannot thank you enough for what you are doing for people who are being handed a death sentence. You have given so many of us hope! Bless you"



Case 8 - 2025: 74 year old North Carolina woman with new Renal Cell Carcinoma (papillary)

Dr. William Makis shared on X (Twitter) in July 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 74 year old North Carolina woman with new Renal Cell Carcinoma (papillary) has tumor shrinkage after 4 months Oncologists have no answers for Kidney Cancer but there is hope! 74 year old North Carolina woman with new Renal Cell Carcinoma (papillary) Regimen (started Feb.16, 2025): Ivermectin 1mg/kg/day Fenbendazole 1000mg/day Results after 4 months Left kidney cancer shrunk 1.4x1.7cm to 0.9x1.3cm = 68.4% tumor volume shrinkage It’s important to note that neither Radiologists, nor Oncologists do any calculations of tumor volume reduction. This radiologist called a 68% tumor volume reduction “mildly decreased”.


Case No. 7: 63 year old Florida man with Stage 4 Clear cell renal cell carcinoma (ccRCC)* metastatic to chest

*Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer, making up about 80% of all kidney cancer cases.

Dr. William Makis shared on X (Twitter) in April 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 63 year old Florida man with Stage 4 Renal Cell Clear Cell Cancer metastatic to chest becomes "CANCER FREE" after 3 months! Renal Cancer is a tough one...or...is it? 62 year old man with history of Stage 3 locally advanced Renal Clear Cell Carcinoma had a 3 cm tumor recurrence in the hilum. In early August 2024, this was one of my first patients. We started: Ivermectin 1mg/kg/day increasing to 2mg/kg/day Fenbendazole 1000mg/day July 2024 PET/CT showed: 3cm hilar metastasis Aug 2024 (early): Ivermectin + Fenbendazole Oncologist: immunotherapy Nov.18, 2024 PET/CT: Cancer Free Apr.5, 2024 PET/CT: Cancer Free April 7 patient wrote me: "I promised I would keep you in the loop on my follow-up PET/CT scan. No evidence of cancer! Again, I want to thank you for helping me. " "Most people I talk to, especially those that have cancer or their loved ones have cancer, think I am nuts with the protocol I take but the results speak for themselves!" "I will keep spreading the word and praying for you and your family" PET/CT April 5, 2025: "No evidence of recurrent or residual renal cell cancer". "The most recent PET/CT showed a complete response" "My Oncologist is thrilled". I bet he is! Because he sure as heck didn't do this. My Take... Quick. Easy. Cancer Free. Look, it honestly doesn't have to be complicated. The good news here is that there wasn't much overall tumor burden to deal with. One 3cm lesion. Patient jumped on this quickly before it spread further and he also knew that the Oncologist, having failed once, probably wasn't going to fix this. Remember, he was cancer free, on top of the line treatment that modern Oncology can offer in the United States (immunotherapy) and he STILL developed a 3cm recurrent cancer! I don't know how he found me, but he did. It was Day 3 of my Cancer Clinic. I'm now in the 8th month.


Case 6: 2 year old girl with Wilm's Tumor (Kidney Cancer) metastatic to the lungs

Dr. William Makis shared on X (Twitter) in April 2025:

IVERMECTIN and MEBENDAZOLE Testimonial - 2 year old girl in India with Wilm's Tumor (Kidney Cancer) metastatic to the lungs is improving. My youngest cancer patient! Let me tell you about my youngest cancer patient.  2 year old girl in Mumbai, India, has a recurrent Wilm's Tumor (pediatric kidney tumor) metastatic to the lungs. She had an operation to remove the tumor in Sep.2024 But it came back in March 2025: "We have today found that she has relapsed in spite of the ongoing chemotherapy". The family reached out to me. We started Ivermectin and Mebendazole. One month later: "Kindly find the latest CT report of the lungs (refractory Wilms tumor metastasis) along with the one from March. This shows a significant improvement in the last 30 days...we have used your protocol" After starting Ivermectin and Mebendazole, she is improving and the lung tumors are shrinking. Largest lung tumor has shrunk from 7.2x6.0cm to 4.6x5.3cm. Radiologist: "Interval regression in size...Imaging features suggest partial response to therapy" These are very difficult cases and I always hesitate to take on pediatric patients.

But if I don’t help, who will?  Pediatric Oncologists don't put their neck on the line any more than adult Oncologists. You don't upset big pharma, or your Oncology career is over, patient be damned. There is research to back the use of Ivermectin and Mebendazole in children. Ivermectin: 
2020 de Castro et al - Continuous high-dose ivermectin appears to be safe in patients with acute myelogenous leukemia and could inform clinical repurposing for COVID-19 infection - three children with leukemia were successfully treated with Ivermectin. Mebendazole: NCT02644291 - Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors This is a safety (Phase 1) trial using mebendazole for recurrent pediatric brain cancers that include medulloblastoma and high grade glioma, that are no longer responding to standard therapies We have shown efficacy in preclinical laboratory models of high grade glioma and medulloblastoma. Mebendazole therapy demonstrated safety in a phase I clinical trial for adults with high grade gliomas such as glioblastoma The patients for this experimental trial are those between the age of 1 to 21 with the diagnosis of medulloblastoma, or high grade glioma, where the tumor has resumed growth or continued to grow despite standard medical therapy. Mebendazole is provided at no cost in the form of a chewable 500 mg tablets, recommended to be taken three times daily with meals or food.  In one month we achieved with Ivermectin and Mebendazole what Oncologists couldn't achieve - the tumors are shrinking. I don't share this case for any reason other than to give hope to parents out there struggling with such cases. This case is in God’s hands. I pray for success.


Case No. 5: 68 yr old Male with Stage 4 Clear Cell Renal Cell Carcinoma - shrinking lung metastases by 60-70%

Dr. William Makis shared on X (Twitter) in March 2025:

Do you think Renal Cell Carcinoma can be beaten? Most doctors will tell you it can't.  Well, they're wrong.  Of course, your local friendly mRNA Vaccinated Oncologist has no chance to even contemplate this. Story: 68 year old man with Stage 4 Clear Cell Renal Cell Carcinoma and lung metastases reached out to my Ivermectin Cancer Clinic.
   Did a 3 month protocol of :
  • Ivermectin 2mg/kg/day
  • Fenbendazole 888mg/day
  • CBD Oil 25mg/day
  • Melatonin 120mg/day
RESULTS: Largest lung metastasis shrunk from 1.3x0.7cm to 1.2x0.3cm. According to Grok, that’s a reduction of 60-70% tumor volume. Another lung nodule shrunk 0.7cm to 0.6cm, a reduction of 37% tumor volume. No chemo. No radiation. No immunotherapy.


Case 4: Renal Cell Carcinoma (Stage 4) - August 2024

Source: William Makis, MD (X.com)


Case 3: Stage 4 Metastatic Clear Cell Renal Carcinoma (aka Kidney cancer) - July, 2022

Husband diagnosed 7/19/21

Stage 4 Metastatic Clear Cell Renal Carcinoma (aka Kidney cancer).

Surgery 8/2/21 left radical nephrectomy with complications and have colostomy

9/2/21 Start Opdivo

10/2021 colostomy reversal

11/2021 land in ER with sepsis (unknown origin) and have surgery

11/2021 Start Yervoy in addition to Opdivo (and FenBen)

11/2021 (just before Thanksgiving), doctor said ”let’s see if you can make it 5 weeks” when husband asked about prognosis

12/21 Travel to NYC to spend what my husband believes is his last Christmas

1/3/21 ER visit due to lack of lucidity

1/22 Start Cabo (have been off FenBen because of all the hospital visits)

2/4/22 see medical consultant – start FenBen again

5/22 – Cancer is shrinking some totally gone – off nearly all pain meds. Doctor says he’s never seen this much progress in such little time.

6/22 – Cancer is still shrinking – off almost every pain med (1 10MG Oxy a day)

7/22 – Cancer still shrinking!! PTL


Case 2: Stage 4 Kidney Cancer (December, 2021)

In 2016 I was diagnosed with stage 4 cancer in my kidney and abdomen alongside a secondary diagnosis of follicular lymphoma. The Oncologist predicted that if I am lucky I will have 6 months left to spare.

I declined any medical help that came my way and decided with dedication and faith to take the natural path to healing from the very beginning of my cancer journey.

It has been a challenging journey for me the last year and I thought I might not make it at one point. But, then, everything started to change and my symptoms were fading slowly but surely from using various methods and eventually ended up taking fenbendazole and following the protocol religiously. I started off on a dose of 150mg and kept on increasing it from there over a period of four months. I showed symptoms when I hit the 600mg dosage and was very concerned that it might not be the best approach and even though I kept on increasing the dose over a reasonable amount of time and took a break off of it for a couple of days before I would continue on it again.

Over the last month the swelling in my face seems to have decreased and I don’t experience anymore pain in my eye, and the lymph nodes were busy disappearing up to the point of not being visible anymore. My persistence and belief in the protocol paid off, this is the least I can say!

I still have a long journey to walk, but I am more motivated than ever and I attribute all the success to the use of this protocol and encourage everyone to give it a go! Do not lose hope.


Case 1: November, 2021

In the beginning of 2021 I was diagnosed with stage three kidney cancer followed by stomach cancer a few months after.

I did not want to go for any radiation or chemo knowing the adverse effects it will have on my body. I jumped onto a fenbendazole course immediately which I followed for a good 6 months and got the incredible news that I am completely cancer free!


See also Bladder (Urinary) Cancer success stories (below)

Urinary Bladder Cancer Success Stories (9 cases)

Case No. 9: 61 year old Virginia man with Bladder Cancer (papillary urothelial carcinoma)

Dr. William Makis shared on X in December 2025:

IVERMECTIN, FENBENDAZOLE, CBD Oil Testimonial - 61 year old Virginia man with Bladder Cancer (papillary urothelial carcinoma) reports after 6 months - two clear cystoscopies...

I've had a fascinating experience with many Bladder Cancer cases on Ivermectin and you know what it is?

Patients can stop bladder cancer from coming back...again, if you have dealt with this before, you know how big this actually is...front page of the New York Times big (well...maybe that's not so desirable anymore.

STORY:
61 year old Virginia man with Bladder Cancer (papillary urothelial carcinoma) In mid July 2025 he started: Ivermectin 1mg/kg/day Fenbendazole 1000mg/day CBD Oil 100mg/day "The doctor mentioned that the walls of the bladder looked better than they had in years and most scar tissue lessened" This one I've heard from many bladder cancer patients on Ivermectin, that things looked "better than they had in years" "cystoscopy showed everything looked even better inside the bladder, no signs of bleeding, no tumors. It's been a couple years since I had two clean cysto's in a row. That's an amazing win!!! Thank you so much!!!"


Case No. 8: 57 year old Chicago man with Stage 4 Small Cell Carcinoma of the Bladder

Dr. William Makis shared on X (Twitter) in September 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 57 year old Chicago man with Stage 4 Small Cell Carcinoma of the Bladder - cancer free after 2 months! We have been particularly successful with bladder cancers of all types. 57 year old Chicago man with Stage 4 Small Cell Carcinoma of the Bladder (very aggressive type) End of May 2025 he started:
  • Ivermectin 1.5mg/kg/day
  • Fenbendazole 1500mg/day
He also had pelvic radiation Results after 2 months: "Today's PET examination demonstrates complete interval resolution of previous hypermetabolic pelvic tumor" "Complete metabolic response to therapy. No FDG avid tumor currently" "Signatera CT DNA bloodwork...is back at zero" From the patient: "This is clearly a success story after starting the protocol with a very aggressive form of cancer. We cannot thank you enough" "They said he is cancer free".


Case 7: 65 year old patient from Sweden with recurrent Bladder (urinary) Cancer

Dr William Makis shared on X/Twitter (April 2025):

IVERMECTIN and FENBENDAZOLE Testimonial - 65 year old patient from Sweden with recurrent Bladder Cancer becomes "Cancer Free" for the first time in 2.5 years! Cancer patients come to me from around the world. This time: Sweden. "I am 65 years old. I was diagnosed with bladder cancer 2 years ago. I have follow-up visits every 3 months and then relapse all the time". This time he did something different, he came to my Ivermectin Cancer Clinic. We started some Ivermectin & Fenbendazole 3 months later... "April 3, it was time again for my cystoscopy of the bladder...doctor said before the examination that now I have to start chemotherapy" 
"This time they did not find a single tumor!!! After the examination, the doctor said I could forget about the chemo, but she couldn't understand how I was suddenly cancer-free" 
"That was absolutely amazing news, and I want to thank you for helping me get cancer-free. Without your help, it wouldn't have been possible".


Case 6 - 2025: 75-year-old man with Stage 4 urothelial bladder cancer with metastases to multiple organs


Description: Shared on March 24, 2025, by @MakisMD, this details a 75-year-old man with Stage 4 urothelial bladder cancer with metastases to multiple organs. He reportedly showed dramatic improvement on PET/CT scans after using ivermectin and fenbendazole.

TREATMENT 
  • Padcev and Keytruda 12/23/2024 to 3/10/2025 
  • Fenbendazole 222mg/d 1/3/2025 to 2/19/2025 
  • Ivermectin 30mg/d 1/20/2025 to 2/19/2025 
  • Fenbendazole 1500mg/d (Makis Protocol) 2/19/2025 - 3/10/2025 
  • Ivermectin 1mg/kg/d (Makis Protocol) 2/19/2025 - 3/10/2025
Related: EV-302: Long-term subgroup analysis from the phase 3 global study of enfortumab vedotin in combination with pembrolizumab (EV+P) vs chemotherapy (chemo) in previously untreated locally advanced or metastatic urothelial carcinoma (la/mUC)


Case 5: Papillary Urothelial Bladder Cancer

Dr William Makis shared on X/Twitter (Feb 2025):

IVERMECTIN and FENBENDAZOLE Testimonial - Bladder Cancer (Papillary Urothelial Carcinoma) - "Cancer Free for the first time since 2014" "Dr.Makis...I'm writing to inform you about my latest bladder biopsy which was negative. Since 2014, every pathology returned was positive for low-grade papillary urothelial tumors, until now" "I started taking Ivermectin 1mg per kilo. Then somehow I was able to get in touch with you to ask if I should do anything else. You mentioned 444mg of Fenbendazole". "Cancer Free for the first time since 2014"
   My Take… "I believe this is my first bladder cancer testimonial. Can you imagine helping someone become "cancer free" for the first time in 10 years?"  Recent research backs the use of Ivermectin + Fenbendazole in bladder cancer: 2024 - Fan et al - Ivermectin Inhibits Bladder Cancer Cell Growth and Induces Oxidative Stress and DNA Damage.
  “Our study showed that in vitro and in vivo, Ivermectin inhibited the growth of bladder cancer cells. In addition, Ivermectin could induce apoptosis, ROS production, DNA damage, and activate ATM/P53 pathway-related proteins in bladder cancer cells. Conclusion: According to these findings, Ivermectin may be a potential therapeutic candidate against bladder cancer due to its significant anti-cancer effect.” 2022 Tung et al - Ivermectin induces cell cycle arrest and caspase-dependent apoptosis in human urothelial carcinoma cells “Ivermectin inhibited growth, regulated the cell cycle, and induced apoptosis in human UC cells. It also induced the activation of both extrinsic and intrinsic caspase-dependent apoptotic pathways. Further investigation revealed that ivermectin induced apoptosis in UC cells is mediated via c-Jun N-terminal kinase signaling. Herein, we demonstrated that Ivermectin can be used as a new therapeutic agent for treating UC cells.” 2021 Chiang et al - Fenbendazole Enhancing Anti-Tumor Effect: A Case Series “A 63-year-old Caucasian female presented with increasing lower urinary tract symptoms and hematuria. CT imaging revealed a 7.5 cm right lateral bladder mass with extension to the right pelvic sidewall and right-sided hydronephrosis requiring percutaneous nephrostomy. There was no evidence of metastatic disease, consistent with clinical T4 tumor. Transurethral Resection of Bladder Tumor (TURBT) demonstrated a large necrotic mass with pathology confirming urothelial carcinoma with 85% squamous and 2% sarcomatoid histology. She was treated with Accelerated Methotrexate, Vinblastine, Doxorubicin, and Cisplatin (AMVAC) for 6 cycles over the course of 4 months along with concurrent Fenbendazole (FBZ) 1 gram three times weekly. Follow-up CT revealed no evidence of disease with minimal residual thickening in the right inferior bladder wall. She declined to proceed with cystectomy and remains on surveillance with no evidence of progression.”
  • Ivermectin 1mg/kg/day.
  • Fenbendazole 444mg/day

Case 4

Wonderful!

Yes, I take three Ivermectin and one Doxycycline when I get up in the morning with a large, 16 oz glass of water. I wait an hour and have some light food (organic eggs and avocado slices, kimchi for example).

At around 5 p.m. I take three Fenbendazole with a light meal with little carb and higher fat/protein.

I started protocol on 11/11/23.

I had surgery on the 22nd of November for the removal of three cancerous tumors from my bladder(my third surgery, and will have an MRI in two weeks to see if muscle invasive as was before.)

As a result of my 11/11 initiation protocol I noticed an area the size of a dime below my left clavicle disappear ( a skin lesion that I had had for 2-3 years that was raised and would be prone to slight bleeding when rubbed too hard with a towel) to now virtually nothing.

I know this protocol was the reason for this healing. Thrilled! I feel this regime is doing the same to any cancer I may have left in my bladder area. I’ll keep you posted.

I am so grateful to you.

Thank YOU!!!!!

Best, K.

(Please note that K. is using a modified ketogenic diet to starve the cancer of sugars and carbohydrates, which we know is what feeds cancers. An important article on this subject is forthcoming, along with a new product that not only serves as a sugar replacement, but, also, helps eradicate both cancers and diabetes.)


Case 2: Plasmacytoid urothelial (bladder) carcinoma (PUC) (Updated February 2023)

Condition: Plasmacytoid urothelial (bladder) carcinoma (PUC)

July 2022:
I was told from the pathologist report that I had Plasmacytoid cancer after they removed two tumors from my bladder. I was informed that this type of cancer is very rare and is highly aggressive and that it doesn’t respond to chemo or radiation and that I was a candidate for bladder removal. I asked how long I had to live and they said they couldn’t tell me for sure maybe a year maybe 6 months they didn’t know how it was going to react. The it was between me and God!!

I walked out with my death sentence in my hand on the papers they gave me of the report an letter from the Dr. It was a difficult time, but I have been in recovery from alcoholism an drug addict for 10 years as of the 2nd of April 2022, this was on April 22nd 2022. I refused to accept it I thought that there must be something I could do I prayed to God for direction!

I thought about contacting MD Anderson and donate my body to them for trials they wanted money up front!! I post my condition on face book so my friends would know, I begin to get calls and text about people using Fenbenzadole found in Dog Dewormer so I googled it and found it.

I started taking Fenben last part of April 2022, and it is July 19th now an I’m still taking it. I quit my job came back to Oklahoma and contact OU Cancer hospital. I went July 15th an had CT’s an scans done to see what the cancer was doing an how it had spread. The Dr. came in and said he couldn’t see any cancer anywhere in my body that had spread and that he couldn’t see any cancer anywhere else or any Tumors or cancer in my Bladder!!!

I take Fenbenzadole every day I have changed my diet I eat only fish an chicken no meat with blood in it, I drink hot lemon juice once a day I eat all kinds of berries an fruits, take vitamins an I believe that that God has healed me through this medicine an I pray that you don’t give up any do what you must if it healed me then maybe it can heal you too.

Update – February 2023:

Yesterday I received my PET scan report. No signs of any METASTATIC DISEASE ANYWHERE! MRI of my brain was NORMAL, NO SIGNS OF CANCER OR TUMORS ANYWHERE !! These factors prove that FENBENZADOLE AND TURMERIC CURCUMIN AND CHANGES IN MY DIET HAVE KILLED THIS RARE AND HIGHLY AGGRESSIVE CANCER WITH KNOW KNOWN CURE ALONG WITH FAITH IN A GOD THAN CAN PERFORM MIRACLES AND STUN THE MEDICAL PEOPLE WHO ARE IN DENIAL ABOUT THIS DRUG!! NOW must continue to follow this path and make the changes to keep cancer free and use Fenbenzadole as I must. Thank you and never give up !!!

Listen here for an interview with Earnest: Earnest Best was Given the Death Sentence and He Didn’t Take It.
 

Case 1: High grade, Urothelial carcinoma (December, 2021)

From high grade, urothelial carcinoma to no evidence of disease (NED) in less than a year – thanks to fenbendazole! I was diagnosed late 2021 with tumors the size of my thumb growing on the inside of my uterus. The tumor was removed as soon as possible with several immunotherapy BCG treatments that followed (delivers immunotherapy drugs directly to your bladder through a catheter).

Related: 
See also Kidney Cancer success stories (above)

Enfortumab Vedotin and Pembrolizumab in Untreated Advanced Urothelial Cancer (EV-302/KEYNOTE-A39) - NEJM 2024

A combination of Keytruda and Astellas and Pfizer’s Padcev won full FDA approval as a first-line treatment for advanced bladder cancer—regardless of the patient’s eligibility for chemotherapy. The approval came after the phase 3 EV-302 trial linked the Keytruda-Padcev combo to a 53% reduction in the risk of death compared with chemo. (EV-302/KEYNOTE-A39)

But the EV-302 readout was viewed as more of a success for Padcev and the antibody-drug conjugate modality, especially given Keytruda’s previous stumbles (KEYNOTE 361) in first-line bladder cancer as a monotherapy and as part of a combination with traditional chemotherapy.

Prolonged Progression-Free Survival, Disease-Free Survival, and Cystectomy Avoidance With IL-15* Receptor Lymphocyte-Stimulating Agent NAI Plus Bacillus Calmette-Guérin in Bacillus Calmette-Guérin-Unresponsive Papillary-Only Nonmuscle-Invasive Bladder Cancer - Journal of Urology 2025

ImmunityBio's data is now published in the Journal of Urology demonstrating bladder preservation and long term disease free survival.

*Note: Anktiva (brand name) is an interleukin-15 (IL-15) receptor agonist, meaning it binds to receptors on immune cells like natural killer (NK) and T cells.

Fenbendazole and Other Stage 4 Cancer Types

The compilation includes over 250 stage 4 cancer case reports across 17 cancer types. Full details are provided in the following: https://www.onedaymd.com/2025/06/ivermectin-fenbendazole-mebendazole-stage-4-cancer.html.


Notes:

No single drug is a miracle cure for all cancers. Taking a particular drug as a stand alone strategy cannot replace an unhealthy lifestyle i.e. heavy smoker, alcoholic, a very stressful and non-active lifestyle, overweight and obesity. All these cancer promoting factors need to change.

The best way to fight cancer is to utilise a menu of strategies by maintaining good health, like from eating a nutritious whole-food diet with lots of fruits and vegetables, avoid ultra processed foods and a healthy lifestyle. Each strategy might produce an incremental improvement in results for some cancers when added to existing treatment regimens.

Everyone’s situation is different, however, it is important to arm yourself with medical knowledge that cancer doctors (Oncologists) may simply not give you.

Whether you’re living with cancer or a survivor, talk to your doctor to determine the best treatment for you.


Disclaimers: 
  • Please do not consider this guide as personal medical advice, but as a recommendation for use by professional providers. Consult with your doctor and discuss with her/him. 
  • Our aim here isn't to replace your doctors' advice. It is intended as a sharing of knowledge and information. Do take note that most treatments are not 100% protective or curative against cancer. It's a continuous struggle between the immune system and the cancer cells. Cancer treatments are meant to assist the immune system in this battle.
  • Cancer treatment should be part of a multi-modal approach in order to provide the best possible outcome. Diet and lifestyle changes are meant to run alongside conventional treatment. They are complementary, not alternative. That said, there is no miracle diet or treatment that can cure all cancers.

Find Integrative Oncologists in USA, Mexico, Europe or Asia

While the potential anti-cancer properties of fenbendazole are intriguing, it’s crucial to approach with caution.

Consulting with an integrative healthcare expert is key to crafting a Fenbendazole protocol tailored to your unique health requirements. 

To find integrative oncologists, check out "find integrative oncologists".

New & Improved Joe Tippens Protocol

In 2016, Joe Tippens was diagnosed with non-small-cell lung cancer with extensive metastatic disease. At the advice of a veterinarian friend, he took Fenbendazole together with nanocurcumin, and three months after starting these drugs his PET scan was completely clear.

Below is a modified version of the Joe Tippens protocol, a synergistic combination of fenbendazole, ivermectin and nutraceuticals, updated based on the ivermectin and mebendazole based protocol published in the Journal of Orthomolecular Medicine (2024):
  • Ivermectin (24 mg, 6 days a week) or in the case of severe aggressive cancers up to 1mg/kg/day.
  • Mebendazole (Dose of 200 - 400 mg/day) or Fenbendazole, commonly taken at 300 mg for six days a week, with doses increasing to up to 1 gram in cases of aggressive cancers.
  • Vitamin D (62.5 mcg [2500 IU] seven days a week).
  • Bio-Available Curcumin (600 mg per day, 7 days a week). 
  • Enhanced absorption Berberine (500 mg per day) to starve your cancer of sugar.
  • Diet and Lifestyle: Eliminate sugar (BMJ 2023), adopt a whole-food diet, avoid ultra-processed foods (BMJ 2024and a healthy lifestyle with quality sleep and proper stress management. 
Notes:
  • Please note that this protocol now includes the vital Vitamin D addition, with the one day off for the fenbendazole administration. This protocol represents the most comprehensive and cutting edge repurposed drug and vitamin treatment approach to date.
  • If you are taking ivermectin and mebendazole, you might not need fenbendazole. Consult your doctor.
  • Vitamin E: Removed from the protocol (Joe Tippens, July 22, 2020) due to interactions (e.g., with blood thinners).

References:
  1. Dr Peter McCullough: How to Detox Spike Protein from Body
  2. FLCCC I-Recover Protocol (Post-Vaccine Treatment Protocol)
  3. Top 10 Repurposed Drugs and Metabolic Interventions for Cancer Treatment
  4. Mebendazole vs fenbendazole for cancer
  5. Enfortumab Vedotin and Pembrolizumab in Untreated Advanced Urothelial Cancer (EV-302/KEYNOTE-A39) - NEJM 2024
  6. 21 year old Washington soccer goalkeeper Mia Hamant died from Stage 4 Kidney Cancer on Nov.6, 2025 (William Makis 2025)
Read More: This article is part of the Winning the War on Cancer series.

Source: Reddit




Ivermectin and mebendazole, both approved for human use, are now available in the U.S.

Researched and approved by Dr. Peter McCullough.
  • Prescribed by licensed medical professionals
  • Compounded and dispensed by a licensed US-based pharmacy
  • Approved for human use
Where to buy Ivermectin and Mebendazole Formula: Available on The Wellness Company's website. Here is the link: Ivermectin and Mebendazole.

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