Fenbendazole in Stage 4 Kidney-Urinary Cancers - the 2021 Stanford University Case Series and More

What is the "Stanford Fenbendazole Protocol"?

I bet you've never heard of the "Stanford Fenbendazole Protocol" for treating Cancer. Yet, it exists. But it's heavily suppressed by search engines and mainstream Oncology, especially in the United States and Canada. In 2021 a group at Stanford University Medical Center, Department of Medicine, published a Case Series (Clin. Oncol. Case Rep 2021)* on a "forbidden" repurposed drug, Fenbendazole.

*Note: Clinical Oncology Case Reports is a peer-reviewed International clinical and medical oncology and cancer research Journal. Clinical Oncology Case Reports (COCR) is a high-impact multidisciplinary journal focus on the area of clinical and medical investigation.

They wrote about 3 cases of Stage 4 Cancer patients who self-treated and cured their cancers.

 

Case 1: 63 year old man with a Stage 4 Renal Cell Carcinoma (clear cell), a 5.3cm mass and mets to pancreas and bone, failed 3 lines of chemo. He achieved remission on 1000mg Fenbendazole 3 times per week and his tumors shrank dramatically. Case 2: 72 year old man with Stage 4 Urothelial Carcinoma of Urethra, developed lung, lymph node and brain metastases. He failed radiotherapy, carboplatin, paclitaxel, pembrolizumab, and 6 cycles of gemcitabine and cisplatin Started 1000mg Fenbendazole orally 3 days per week, Vitamin E 800mg daily, Curcumin 600mg daily and CBD Oil CT scan showed tumor shrinkage of 2cm aortocaval node metastasis until it disappeared (complete radiographic response). Case 3: 63 year old woman with Stage 4 Urothelial Carcinoma of Bladder, with a 7.5cm tumor and extension to pelvic side wall. She took combination of Chemotherapy WITH Fenbendazole 1000mg three times a week. Follow-up CT revealed no evidence of disease. Sources and References:

• Fenbendazole Enhancing Anti-Tumor Effect: A Stanford University Case Series
• https://x.com/MakisMD/status/1822335996651770172

For more Fenbendazole in Genito-Urinary stage 4 cancer case series, check out the case reports below. 

Kidney Cancer Success Stories (5 cases)

Case No. 5 - 2025: 42 year old woman with Stage 4 Kidney Cancer to lungs, liver and shoulder

Dr. William Makis shared on X.com in August 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 42 year old woman with Stage 4 Kidney Cancer to lungs, liver and shoulder, is CANCER FREE after one year! STORY: 42 year old woman with Stage 4 Kidney Cancer to lungs, liver and shoulder Started Ivermectin and Fenbendazole Reports back after 1 year: "my scan today showed NED (No Evidence of Disease)." "I cannot thank you enough for what you are doing for people who are being handed a death sentence. You have given so many of us hope! Bless you"

Case No. 4: 63 year old Florida man with Stage 4 Clear cell renal cell carcinoma (ccRCC)* metastatic to chest

Dr. William Makis shared on X (Twitter) in April 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 63 year old Florida man with Stage 4 Renal Cell Clear Cell Cancer metastatic to chest becomes "CANCER FREE" after 3 months! Renal Cancer is a tough one...or...is it? 62 year old man with history of Stage 3 locally advanced Renal Clear Cell Carcinoma had a 3 cm tumor recurrence in the hilum. In early August 2024, this was one of my first patients. We started: Ivermectin 1mg/kg/day increasing to 2mg/kg/day Fenbendazole 1000mg/day July 2024 PET/CT showed: 3cm hilar metastasis Aug 2024 (early): Ivermectin + Fenbendazole Oncologist: immunotherapy Nov.18, 2024 PET/CT: Cancer Free Apr.5, 2024 PET/CT: Cancer Free April 7 patient wrote me: "I promised I would keep you in the loop on my follow-up PET/CT scan. No evidence of cancer! Again, I want to thank you for helping me. " "Most people I talk to, especially those that have cancer or their loved ones have cancer, think I am nuts with the protocol I take but the results speak for themselves!" "I will keep spreading the word and praying for you and your family" PET/CT April 5, 2025: "No evidence of recurrent or residual renal cell cancer". "The most recent PET/CT showed a complete response" "My Oncologist is thrilled". I bet he is! Because he sure as heck didn't do this. My Take... Quick. Easy. Cancer Free. Look, it honestly doesn't have to be complicated. The good news here is that there wasn't much overall tumor burden to deal with. One 3cm lesion. Patient jumped on this quickly before it spread further and he also knew that the Oncologist, having failed once, probably wasn't going to fix this. Remember, he was cancer free, on top of the line treatment that modern Oncology can offer in the United States (immunotherapy) and he STILL developed a 3cm recurrent cancer! I don't know how he found me, but he did. It was Day 3 of my Cancer Clinic. I'm now in the 8th month.

*Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer, making up about 80% of all kidney cancer cases.

Case No. 3: 68 yr old Male with Stage 4 Clear Cell Renal Cell Carcinoma - shrinking lung metastases by 60-70%! 

Dr. William Makis shared on X (Twitter) in March 2025:

Do you think Renal Cell Carcinoma can be beaten? Most doctors will tell you it can't.  Well, they're wrong.  Of course, your local friendly mRNA Vaccinated Oncologist has no chance to even contemplate this. Story: 68 year old man with Stage 4 Clear Cell Renal Cell Carcinoma and lung metastases reached out to my Ivermectin Cancer Clinic.

   Did a 3 month protocol of :

• Ivermectin 2mg/kg/day
• Fenbendazole 888mg/day
• CBD Oil 25mg/day
• Melatonin 120mg/day

RESULTS: Largest lung metastasis shrunk from 1.3x0.7cm to 1.2x0.3cm. According to Grok, that’s a reduction of 60-70% tumor volume. Another lung nodule shrunk 0.7cm to 0.6cm, a reduction of 37% tumor volume. No chemo. No radiation. No immunotherapy.

Case No. 2: Stage 4 Metastatic Clear Cell Renal Carcinoma (aka Kidney cancer) - July, 2022

Husband diagnosed 7/19/21

Stage 4 Metastatic Clear Cell Renal Carcinoma (aka Kidney cancer).

Surgery 8/2/21 left radical nephrectomy with complications and have colostomy

9/2/21 Start Opdivo

10/2021 colostomy reversal

11/2021 land in ER with sepsis (unknown origin) and have surgery

11/2021 Start Yervoy in addition to Opdivo (and FenBen)

11/2021 (just before Thanksgiving), doctor said ”let’s see if you can make it 5 weeks” when husband asked about prognosis

12/21 Travel to NYC to spend what my husband believes is his last Christmas

1/3/21 ER visit due to lack of lucidity

1/22 Start Cabo (have been off FenBen because of all the hospital visits)

2/4/22 see medical consultant – start FenBen again

5/22 – Cancer is shrinking some totally gone – off nearly all pain meds. Doctor says he’s never seen this much progress in such little time.

6/22 – Cancer is still shrinking – off almost every pain med (1 10MG Oxy a day)

7/22 – Cancer still shrinking!! PTL


Case No. 1: Stage 4 Kidney Cancer (December, 2021)

In 2016 I was diagnosed with stage 4 cancer in my kidney and abdomen alongside a secondary diagnosis of follicular lymphoma. The Oncologist predicted that if I am lucky I will have 6 months left to spare.

I declined any medical help that came my way and decided with dedication and faith to take the natural path to healing from the very beginning of my cancer journey.

It has been a challenging journey for me the last year and I thought I might not make it at one point. But, then, everything started to change and my symptoms were fading slowly but surely from using various methods and eventually ended up taking fenbendazole and following the protocol religiously. I started off on a dose of 150mg and kept on increasing it from there over a period of four months. I showed symptoms when I hit the 600mg dosage and was very concerned that it might not be the best approach and even though I kept on increasing the dose over a reasonable amount of time and took a break off of it for a couple of days before I would continue on it again.

Over the last month the swelling in my face seems to have decreased and I don’t experience anymore pain in my eye, and the lymph nodes were busy disappearing up to the point of not being visible anymore. My persistence and belief in the protocol paid off, this is the least I can say!

I still have a long journey to walk, but I am more motivated than ever and I attribute all the success to the use of this protocol and encourage everyone to give it a go! Do not lose hope.

See also Bladder (Urinary) Cancer success story below. 

Stage 4 Urinary Bladder Cancer Success Story

Case No. 1 - 2025: Stage 4 Urothelial Bladder Cancer

Link: https://t.co/eJLohDUh5q

Description: Shared on March 24, 2025, by @MakisMD, this details a 75-year-old man with Stage 4 urothelial bladder cancer with metastases to multiple organs. He reportedly showed dramatic improvement on PET/CT scans after using ivermectin and fenbendazole.

TREATMENT 

• Padcev and Keytruda 12/23/2024 to 3/10/2025 
• Fenbendazole 222mg/d 1/3/2025 to 2/19/2025 
• Ivermectin 30mg/d 1/20/2025 to 2/19/2025 
• Fenbendazole 1500mg/d (Makis Protocol) 2/19/2025 - 3/10/2025 
• Ivermectin 1mg/kg/d (Makis Protocol) 2/19/2025 - 3/10/2025

Fenbendazole and Other Stage 4 Cancer Types

The compilation includes over 140 stage 4 cancer case reports across 17 cancer types. Full details are provided in the following: https://www.onedaymd.com/2025/06/ivermectin-fenbendazole-mebendazole-stage-4-cancer.html.

Notes:

No single drug is a miracle cure for all cancers. Taking a particular drug as a stand alone strategy cannot replace an unhealthy lifestyle i.e. heavy smoker, alcoholic, a very stressful and non-active lifestyle, overweight and obesity. All these cancer promoting factors need to change.

The best way to fight cancer is to utilise a menu of strategies by maintaining good health, like from eating a nutritious whole-food diet with lots of fruits and vegetables, avoid ultra processed foods and a healthy lifestyle. Each strategy might produce an incremental improvement in results for some cancers when added to existing treatment regimens.

Everyone’s situation is different, however, it is important to arm yourself with medical knowledge that cancer doctors (Oncologists) may simply not give you.

Whether you’re living with cancer or a survivor, talk to your doctor to determine the best treatment for you.

Disclaimers: 

• Please do not consider this guide as personal medical advice, but as a recommendation for use by professional providers. Consult with your doctor and discuss with her/him. 
• Our aim here isn't to replace your doctors' advice. It is intended as a sharing of knowledge and information. Do take note that most treatments are not 100% protective or curative against cancer. It's a continuous struggle between the immune system and the cancer cells. Cancer treatments are meant to assist the immune system in this battle.
• Cancer treatment should be part of a multi-modal approach in order to provide the best possible outcome. Diet and lifestyle changes are meant to run alongside conventional treatment. They are complementary, not alternative. That said, there is no miracle diet or treatment that can cure all cancers.

Find Integrative Oncologists in USA, Mexico, Europe or Asia

While the potential anti-cancer properties of fenbendazole are intriguing, it’s crucial to approach with caution.

Consulting with an integrative healthcare expert is key to crafting a Fenbendazole protocol tailored to your unique health requirements. 

To find integrative oncologists, check out "find integrative oncologists".

New & Improved Joe Tippens Protocol

In 2016, Joe Tippens was diagnosed with non-small-cell lung cancer with extensive metastatic disease. At the advice of a veterinarian friend, he took Fenbendazole together with nanocurcumin, and three months after starting these drugs his PET scan was completely clear. 

Below is a modified version of the Joe Tippens protocol, a synergistic combination of fenbendazole,ivermectin and nutraceuticals, as recommended by Canadian oncologist Dr. William Makis.

• Fenbendazole is commonly taken at 300 mg for six days a week, with doses increasing to up to 1 gram in cases of aggressive "turbo cancers." The original Joe Tippens protocol recommended the Panacur C brand of fenbendazole. 
• Ivermectin (24 mg, 7 days a week) or in the case of severe turbo cancers up to 1mg/kg/day.
• Lifestyle: Eliminate sugar (BMJ 2023), adopt a whole-food diet, avoid ultra-processed foods (BMJ 2024), prioritize sleep, and manage stress.
• Bio-Available Curcumin (600mg per day, 7 days a week). 
• Vitamin D (62.5 mcg [2500 IU] seven days a week).
• Enhanced absorption Berberine (500mg per day) if you are trying to starve your cancer of sugars.

Please note that this protocol now includes the vital Vitamin D addition, with the one day off for the fenbendazole administration. This protocol represents the most comprehensive and cutting edge repurposed drug and vitamin treatment approach to date.

*Note: If you are taking ivermectin and mebendazole, you might not need fenbendazole. Consult your doctor.

• Vitamin E: Removed from the protocol (Joe Tippens, July 22, 2020) due to interactions (e.g., with blood thinners).

Source: Adapted from OneDayMD.com. https://www.onedaymd.com/2024/11/fenbendazole-and-cancer-15-minutes-with.html (November 2024).

References:

• Dr Peter McCullough: How to Detox Spike Protein from Body
• FLCCC I-Recover Protocol (Post-Vaccine Treatment Protocol)
• Top 10 Repurposed Drugs and Metabolic Interventions for Cancer Treatment
• Can Diet and Lifestyle influence your Risk of getting Cancer?
• Mebendazole vs fenbendazole for cancer

Read More: This article is part of the Winning the War on Cancer series.

Source: Reddit

The Wellness Company's Ivermectin and Mebendazole

Ivermectin and mebendazole, both approved for human use, are now available in the U.S.

Researched and approved by Dr. Peter McCullough.

• Prescribed by licensed medical professionals
• Compounded and dispensed by a licensed US-based pharmacy
• Approved for human use

Where to buy Ivermectin and Mebendazole Formula: Available on The Wellness Company's website. Here is the link: Ivermectin and Mebendazole.