Mebendazole and Triple Negative Breast Cancer brain metastases (2024)

Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype that metastasizes to the central nervous system (CNS) in up to 50% of affected patients Once disseminated to CNS, TNBC carries poor prognosis, with limited treatment options, and a median survival of only 5 months (much less if you have been COVID-19 mRNA Vaccinated) Among breast cancer subtypes, TNBC accounts for the shortest time between primary diagnosis and CNS metastasis.


In 2024, a group of Stanford researchers led by Rodrigues et al, published an impressive pre-clinical study on the cousin of Fenbendazole - Mebendazole*.

*Fenbendazole and Mebendazole are part of a larger group of drugs known as benzimidazole, which are anthelmintic drugs (i.e., drugs that kill parasitic worms including threadworms, whipworms, hookworms, and roundworms). The class of drugs known as benzimidazoles includes fenbendazole, mebendazole, albendazole and flubendazole. 
Mebendazole was developed in the 1960s to treat a range of gastrointestinal helminth infections, and it is still one of the most commonly used medications in the world "its relatively small size and lipophilic properties render it an appropriate agent to be repurposed for CNS pathologies" In this study, Mebendazole had a notable effect on the growth of TNBC tumors, which was dose dependent. Compared to the control, Mebendazole treatment significantly extended survival in the TNBC model Histological examination of brain sections revealed that Mebendazole effectively reduced metastatic dissemination in the TNBC model, with a significant effect on single cell and small metastasis populations CONCLUSION: "Our data suggest that Mebendazole targets cancers with high migratory capacity & may be particularly effective when these cancers spread into leptomeningeal space" "Consistent with the strong inhibitory effect of Mebendazole on migration of TNBC cells, Mebendazole extended survival of mice with TNBC Leptomeningeal Disease" "Mebendazole was demonstrated to be a safe and effective oral agent in an aggressive animal model of TNBC CNS metastasis." The anti-parasitic Mebendazole (a relative of Fenbendazole) is going to be a key anti-TNBC drug going forward, especially in individuals who took COVID-19 mRNA Vaccines and developed Turbo Cancer TNBC.

Are there more? For more Fenbendazole case series, check out Fenbendazole Cancer Case Series.

Notes:

No single drug is a miracle cure for all cancers. Taking a particular drug as a stand alone strategy cannot replace an unhealthy lifestyle i.e. heavy smoker, alcoholic, a very stressful and non-active lifestyle, overweight and obesity. All these cancer promoting factors need to change.

The best way to fight cancer is to utilise a menu of strategies by maintaining good health, like from eating a nutritious whole-food diet with lots of fruits and vegetables, avoid ultra processed foods and a healthy lifestyle. Each strategy might produce an incremental improvement in results for some cancers when added to existing treatment regimens.

Everyone’s situation is different, however, it is important to arm yourself with medical knowledge that cancer doctors (Oncologists) may simply not give you.

Whether you’re living with cancer or a survivor, talk to your doctor to determine the best treatment for you.

Disclaimers: 
  • Please do not consider this guide as personal medical advice, but as a recommendation for use by professional providers. Consult with your doctor and discuss with her/him. 
  • Our aim here isn't to replace your doctors' advice. It is intended as a sharing of knowledge and information. Do take note that most treatments are not 100% protective or curative against cancer. It's a continuous struggle between the immune system and the cancer cells. Cancer treatments are meant to assist the immune system in this battle.
  • Cancer treatment should be part of a multi-modal approach in order to provide the best possible outcome. Diet and lifestyle changes are meant to run alongside conventional treatment. They are complementary, not alternative. That said, there is no miracle diet or treatment that can cure all cancers.

Find Integrative Oncologists in USA, Mexico, Europe or Asia

While the potential anti-cancer properties of fenbendazole are intriguing, it’s crucial to approach with caution.

Consulting with an integrative healthcare expert is key to crafting a Fenbendazole protocol tailored to your unique health requirements. 

To find integrative oncologists, check out "find integrative oncologists".

New & Improved Joe Tippens Protocol

Adapted from: 2ndsmartestguyintheworld.com/p/synergistic-pairing-of-ivermectin

References:

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