10 Best Probiotic Supplements of 2025: Price and Reviews
Probiotics are living microorganisms that offer lots of health benefits if consumed in sufficient amounts, such as balancing the “good” bacteria in your digestive system, strengthening immune system, and lowering the risk and severity of diarrhoea. Many studies also linked probiotics with improvement in mental health conditions such as anxiety, depression, and stress.
The global gut health is predicted to grow by around 8% annually at least to the end of the decade. There are a number of factors combining to drive growth in the gut and digestive health market. One is that consumers are increasingly aware of the importance of gut health and comfort, and that they can, to some extent, manage that themselves through food choices and supplements. This is linked to the fact that global populations are ageing, and more and more people are living with chronic gastric disorders. At the same time, scientists are gaining better understanding of both the importance of the gut (microbiome) on human health and how we can influence it.
The global gut health is predicted to grow by around 8% annually at least to the end of the decade. There are a number of factors combining to drive growth in the gut and digestive health market. One is that consumers are increasingly aware of the importance of gut health and comfort, and that they can, to some extent, manage that themselves through food choices and supplements. This is linked to the fact that global populations are ageing, and more and more people are living with chronic gastric disorders. At the same time, scientists are gaining better understanding of both the importance of the gut (microbiome) on human health and how we can influence it.
Probiotics can be found in fermented foods such as yogurt and high-fiber vegetables. However, it is still possible that you aren’t getting enough probiotics from your diet, therefore a probiotics supplement is a good solution for a better result.
Best Probiotics for Men
Inflammation and dysbiosis the most studied conditions for probiotics in recent years – new probiotics database (ProBioQuest)
Where can I buy probiotic supplements? Here are the Best Probiotic Supplements of 2022, along with their outstanding performance and honest customers’ reviews.
Physician's CHOICE Probiotic formulation is made with prebiotics and probiotics based on clinical research without unnecessary binders, soy, gluten, milk, egg, wheat, peanuts, shellfish, or preservatives. They provide you exactly what's on the label with 10 probiotic strains, 60 Billion Cfu, and an organic prebiotic blend. Moreover, in order to ensure the stability of their products, they designed a Patented Shelf-Stable bottle.
Their probiotic daily blend, combined with an organic prebiotic fiber blend, helps to support the stomach's digestive environment and supports the natural stomach balance. Excellent for digestive health and intestinal health, as well as occasional gas relief, bloating relief, constipation, digestive health, and intestinal health. Last but not least, regarding their safety, this probiotic is 3rd-party tested for purity and potency.
An increased level of the Akkermansia muciniphila strain in the gut results in a stronger intestinal wall, which is important for keeping your digestive system in good shape. This unique strain is called a keystone strain for gut health as it restores, protects, and strengthens the digestive lining. Take 1 capsule daily to help fuel and boost your gut microbiome and eliminate digestive problems. A well-balanced gut microbiome helps with overall health. Higher amounts of Akkermansia muciniphila mean your gut is healthier, so take a probiotic that contains this beneficial bacteria.
"The beneficial oxygen-intolerant bacteria Akkermansia muciniphila is essential for a healthy microbiome, but many people have few to none at all. When selecting Akkermansia supplements, choose those that utilize advanced, timed-release capsules or microencapsulation technology. These methods keep the bacteria dormant and protected until they reach your colon, typically within two to four hours after ingestion, ensuring that a higher number of live bacteria survive the journey through your digestive system." - Dr Joseph Mercola.
- Once Daily Probiotics for Women: A probiotic supplement for women with 50 Billion CFUs plus clinically proven ingredients to help promote digestion, immune support and feminine health. Organic prebiotics and 6 probiotic strains with D-Mannose & ProCran, a science backed cranberry extract that provides powerful antioxidants. 50 mg of ProCran is equivalent to 2,500 mg of cranberries without the sugar and calories.
Wholesome Wellness Raw Probiotic contains 100 Billion Cfu & 34 Strains per serving or 3 Trillion Cfu per bottle. This probiotic is made with genuine prebiotics, digestive enzymes, and probiotics based on clinical testing. Their formulation is free from binders, soy, gluten, milk, egg, wheat, peanuts, shellfish, additives, and preservatives.
The capsules are designed with Timed Release Technology in order to work effectively. How? This technology ensures that their raw probiotics stay safe, secure, and alive as they travel to your intestines, while some other probiotics are released before they reach the intestines which makes them ineffective.
Regarding their quality, this probiotic is GMP Certified. They guarantee their high-quality supplements will actually work to support the free stomach digestive environment biotics condition and supports the natural stomach balance. Moreover, their raw probiotics are shelf-stable and no refrigeration is required.
Best Probiotics for Women
1. Physician's CHOICE Probiotics 60 Billion CFU - Probiotics and Prebiotics for Gut Health
Rating: 4.5/5 - More than 120,000 ratings
#1 Amazon's Best Seller in the Probiotics Category
• 30 Veggie Capsules
• 60 Billion CFUs per serving.
• Made with 10 probiotic strains & Non-GMO ingredients
• Patented Shelf-Stable bottle
• Made with 10 probiotic strains & Non-GMO ingredients
• Patented Shelf-Stable bottle
Physician's CHOICE Probiotic formulation is made with prebiotics and probiotics based on clinical research without unnecessary binders, soy, gluten, milk, egg, wheat, peanuts, shellfish, or preservatives. They provide you exactly what's on the label with 10 probiotic strains, 60 Billion Cfu, and an organic prebiotic blend. Moreover, in order to ensure the stability of their products, they designed a Patented Shelf-Stable bottle.
Their probiotic daily blend, combined with an organic prebiotic fiber blend, helps to support the stomach's digestive environment and supports the natural stomach balance. Excellent for digestive health and intestinal health, as well as occasional gas relief, bloating relief, constipation, digestive health, and intestinal health. Last but not least, regarding their safety, this probiotic is 3rd-party tested for purity and potency.
2. Pendulum Akkermansia Probiotic with Prebiotic Fiber
Rating: 4.2/5 - More than 900 ratings
- Next generation probiotic
- Unique delivery system, including chicory inulin and a plant-based, acid resistant, delayed release capsule, so that the strain gets through the stomach acid and nurtures a thriving microbiome.
Pendulum Akkermansia contains 100 million AFU of a patented strain of Akkermansia muciniphila. It is a novel probiotic strain that naturally occurs in the layer of the large intestines and works by protecting and enhancing the gut lining. Studies show that the Akkermansia strain makes up approximately 4% of the intestinal bacteria in healthy people, making it essential for a healthy gut microbiome. Akkermansia increases the levels of these good bacteria in your gut.
An increased level of the Akkermansia muciniphila strain in the gut results in a stronger intestinal wall, which is important for keeping your digestive system in good shape. This unique strain is called a keystone strain for gut health as it restores, protects, and strengthens the digestive lining. Take 1 capsule daily to help fuel and boost your gut microbiome and eliminate digestive problems. A well-balanced gut microbiome helps with overall health. Higher amounts of Akkermansia muciniphila mean your gut is healthier, so take a probiotic that contains this beneficial bacteria.
"The beneficial oxygen-intolerant bacteria Akkermansia muciniphila is essential for a healthy microbiome, but many people have few to none at all. When selecting Akkermansia supplements, choose those that utilize advanced, timed-release capsules or microencapsulation technology. These methods keep the bacteria dormant and protected until they reach your colon, typically within two to four hours after ingestion, ensuring that a higher number of live bacteria survive the journey through your digestive system." - Dr Joseph Mercola.
3. Best Probiotic for Women Weight Loss - Physician's Choice Probiotics for Women
Ratings: 4.5 out of 5 – more than 48,000 global ratings
Amazon Best Sellers Rank: #1 in Prebiotic Nutritional Supplements
Amazon Best Sellers Rank: #2 in Probiotic Nutritional Supplements
Amazon Best Sellers Rank: #2 in Probiotic Nutritional Supplements
4. NewRhythm Probiotics 50 Billion CFU 20 Strains - Probiotics Without Sugar
Rating: 4.6/5 - More than 30,000 ratings
Amazon Best Sellers Rank: #9 in Probiotic Nutritional Supplements
• 60 Vegetarian Capsules
• 50 Billion CFUs per serving.
• Made with Non-GMO ingredients
• Fridge-free
• Made with Non-GMO ingredients
• Fridge-free
NewRhythm Probiotic contains 50 Billion Living Organisms per serving. Their formulation is made with 100% natural ingredients, verified non-GMO, and free from gluten, sugar, soy, yeast, egg, magnesium stearate, artificial ingredients, preservatives. Featuring Targeted Release Technology to help probiotics survive stomach acids and reach your intestinal tract.
This potent and pure probiotic can help support healthy digestion and balanced intestinal ecology. Moreover, good news for travelers! Their product is shelf-stable and they do not require refrigeration. Regarding their quality, NewRhythm Probiotc obtained Good Manufacturing Practices (GMP) certification, which represents the highest level of technology, quality purity, and consistency.
5. Wholesome Wellness Raw Probiotic 100 Billion CFU - Probiotics and Digestive Enzymes
Rating: 4.5/5 - More than 18,000 ratings
• 30 Vegetable Capsules
• 100 Billion CFU, 34 Strains
• No refrigeration required
• Non-GMO ingredients
Wholesome Wellness Raw Probiotic contains 100 Billion Cfu & 34 Strains per serving or 3 Trillion Cfu per bottle. This probiotic is made with genuine prebiotics, digestive enzymes, and probiotics based on clinical testing. Their formulation is free from binders, soy, gluten, milk, egg, wheat, peanuts, shellfish, additives, and preservatives.
The capsules are designed with Timed Release Technology in order to work effectively. How? This technology ensures that their raw probiotics stay safe, secure, and alive as they travel to your intestines, while some other probiotics are released before they reach the intestines which makes them ineffective.
Regarding their quality, this probiotic is GMP Certified. They guarantee their high-quality supplements will actually work to support the free stomach digestive environment biotics condition and supports the natural stomach balance. Moreover, their raw probiotics are shelf-stable and no refrigeration is required.
6. Florastor Daily Probiotic Supplement for Women and Men
Ratings : 4.8 out of 5 - More than 6,000 global ratings
Amazon Best Sellers Rank: #7 in Probiotic Nutritional Supplements
Proven to Support Digestive Health, Saccharomyces Boulardii CNCM I-745 (100 Capsules)
Daily Probiotic Supplement
Each capsule contains 250mg of our unique probiotic strain, which is larger and stronger than many other probiotics and provides increased intestinal coverage and protection
Digestive and Immune Support
Florastor helps increase the natural flora in your digestive tract and supports overall health by strengthening your digestive balance and supporting a healthy immune system
Healthy Lifestyle
Made with ingredients found in nature that are vegetarian, gluten-free, and appropriate for lactose intolerance, Florastor probiotics complement your healthy and active lifestyle
No Refrigeration Required
Our capsules and powder sachets do not require refrigeration and have a 3-year shelf life. You can swallow capsules whole or mix the powder into your favorite food or beverage
About a week ago, I came home from work absolutely defeated and at the end of my rope. I had only eaten 2 eggs the whole day and I felt completely swollen and looked 6 months pregnant. The last doctor I went to had briefly mentioned probiotics and I had a bottle of Florastor sitting in my medicine cabinet that I never tried. I took 2 pills in the evening and shortly after felt a slight burn in my stomach. I went to sleep that night and the next morning woke up with no bloat. Later in the morning, I had the best bowel movement I’ve had in 1.5 yrs (sorry tmi) and since then I have been feeling great! I take 2 pills in the morning on an empty stomach & 2 pills before dinner in the evening. I feel like the old me! No more bloat, no more GI issues, digestion is exactly how it was before I got sick and I’ve even lost a few pounds! I don’t feel swollen or defeated anymore. I feel like me again! Thank you Florastor, you saved my life!!!
7. Garden of Life Probiotics for Men and Adults - Best Probiotics with Lactobacillus
Rating: 4.7/5 - More than 6,000 ratings
This unique formula is created exclusively for men, with a high potency count of beneficial probiotics made from diverse strains, including Lactobacilli and Bifidobacteria, that are resistant to stomach acid and bile, to support colon health and support immune digestive system health. Each capsule has a powerful 50 billion CFU tailored to support men’s daily gastrointestinal health.
No refrigeration needed—suitable for travel use! Their supplement is also shelf-stable to ensure your probiotics arrive alive and stay alive. Moreover, their ingredients are verified non-GMO, dairy-free, certified gluten-free by NSF, soy-free, and vegetarian.
• 30 Vegetarian Capsules
• Specially designed for Men
• No refrigeration required
• Non-GMO ingredients
No refrigeration needed—suitable for travel use! Their supplement is also shelf-stable to ensure your probiotics arrive alive and stay alive. Moreover, their ingredients are verified non-GMO, dairy-free, certified gluten-free by NSF, soy-free, and vegetarian.
8. Garden of Life Whole Food Probiotic Supplement - Best Probiotics Without Soy
Ratings : 4.8 out of 5 - more than 2,000 global ratings
- Primal Defense Ultra Ultimate for Digestive and Gut Health
- 216 Vegetarian Capsules
DIGESTION SUPPORT
Primal Defense 15 billion CFU probiotic supplement contains Lactobaccilus acidophilus, Bifidobacteria, and other strains to maximize the benefits of a healthy diet, boost nutrient absorption, relieve constipation and support digestive health.
SOIL BASED PROBIOTICS
The only shelf stable probiotic powder formula containing a unique whole food blend with Homeostatic Soil Organisms (HSO)
IMMUNE SUPPORT
This dietary supplement has 15 billion CFU and 13 hardy beneficial strains for immune system health. Supports normal digestion of dairy products. Soy free.
COLON HEALTH SUPPORT
These probiotics for constipation promote regular, healthy and comfortable bowel movements.
VEGETARIAN PROBIOTIC
Whole food, gluten free, vegetarian probiotics supplement for a balanced, health internal environment.
This comes from a trusted brand and I'm using quiet a lot of products from this brand.
I can kuch for this probiotic and I must say extremely effective.
9. Lifted Naturals Mood Boosting Probiotic - Best Probiotics for Mood and Anxiety
Ratings: 4.3 out of 5 - more than 1,800 global ratings
Mood Boosting Probiotic is our original MOOD formulated probiotic featuring 9 feel-good strains of probiotic bacteria + prebiotic GOS; all designed to help with mood health, digestive health, and immune health.
Recent studies have proven that adding beneficial bacteria to the gut can reduce stress in the body and promote feelings of wellbeing. We've included the best bacterial strains to help with mood and aid the body's stress response.
- 30 Billion CFU
- Mood Boosting Supplement w/ prebiotics & probiotics for Women and Men
- 60 Days Supply
- Supports Digestive Health
- Shelf Stable Probiotic Supplement
- Vegan, Non-GMO
TARGETED "FEEL GOOD" STRAINS - This formula features the TOP performing bacterial strains to help with mood.
30 BILLION CFU with the BEST probiotic strains for MOOD and DIGESTION make it a HIGH POTENCY probiotic... offering digestive, immune, and mood support. 60 Capsules per bottle -- a TWO MONTH supply!
9 NOURISHING STRAINS. In addition to B. Infantis and B. Longum, we included seven more strains (9 various strains total) to ensure healthy digestion, immunity and mood support
I take this product with an SSRI and a mood stabilizer. The product nothing short of amazing and works better the longer you take it!!! I'm very in tune with my body and noticed a difference the first day! It has helped tremendously with both depression and anxiety.
10. Best Lactobacillus Gasseri probiotic for Weight loss - Physician's Choice Thin 30 Probiotic
Amazon Reviews: 4.1 out of 5 – more than 13,000 global ratings
Amazon Best Sellers Rank: #17 in Probiotic Nutritional Supplements
- In a clinical study, 100 patients lost an average of over 30 lbs. in 90 days taking 300 mg of stimulant-free Greenselect Phytosome daily with a reduced-calorie diet. Greenselect is a caffeine-free extract from green tea.
- In a clinical study, 100 patients lost an average of over 30 lbs. in 90 days taking 300 mg of stimulant-free Greenselect Phytosome daily with a reduced-calorie diet. Greenselect is a caffeine-free extract from green tea.
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