Is a combination of Fenbendazole and Ivermectin a real cancer killer?

Fenbendazole and/or Mebendazole seem the perfect pairing with Ivermectin as an off label combination against cancer; recent research shows this 3-in-1 combination attacks the mitochondrial stem cell connection.

I am increasingly asked by cancer patients about the combination of anthelmintic Fenbendazole and Ivermectin against cancer.

Importantly, these patients aren’t the usual stage 2 cancer patients for whom conventional medicine still has a long way to go. These belong to two distinct groups.

First, there are older men whose lung cancer or prostate cancer has returned and they feel that conventional medicine (which they had before) didn’t work before, so why would it work next time. They subscribe to Einstein’s definition of insanity - doing the same thing over and over again and expecting a different result.

Secondly, and this is an equally big group of patients - under 40s with rampant breast cancer, colorectal cancer or lymphoma - the 'early onset' cancer victims. Yes, I did use the word ‘victims’ - this group have ‘turbo cancers’ a new condition not witnessed before the Pandemic. Yale Medical School has identified them.

 

Go to: Yale Medicine seeing the growth of Turbo cancer

 

Now, I have been posting research on off-label drugs since 2007; the first being Low Dose Naltrexone. Next, it was Metformin and Atorvastatin. We’ve covered at least 40 on the CANCERactive Website.

 

I have previously suggested two protocols that have since worked for patients. We have a CANCERactive protocol involving Fenbendazole; and a p53 protocol involving Niclosamide..

 

If you don’t want any more chemo or radiotherapy because of the past poor performance and the debilitating side-effects, why wouldn’t you ask about off-label drugs? They generally have few side-effects and because they’ve been around for years, any side-effects are well known.

 

The problem is that none has a proper Phase III clinical trial behind them. Of course not. Off label drugs are largely off patent and cheap and, worse, could take serious volume and profits away from Big Pharma. So who is going to fund the trials?

 

An off label protocol that delivers?

 

In building a protocol the big question is where to start? You need 'an attack dog'. I like the benzimidazoles - especially Fenbendazole and Mebendazole. They yield consistent results - prostate cancer, lung cancer, TNBC, pancreatic cancer, colorectal cancer and more. They block multiple cancer pathways and with recent pancreatic cancer and TNBC research there were even pictures in the research showing the disappearance of cancer cells from tumours. But then, I've said all this before.

 

Fenbendazole is licensed for animals - Go to review on Fenbendazole

 

Mebendazole is licensed for humans - Go to review on Mebendazole

 

Actually, Mebendazole and Fenbendazole, although they belong to the same class of drugs, have slightly differing and complementary benefits. You could even use both, although with slightly different protocols. We have been covering these drugs for over a decade. Fenbendazole was included in the CANCERactive enhanced off label drug protocol.

 

But, it’s not enough to merely knock a tumour back. You need to damage and ideally eradicate the Cancer Stem Cells. The cells that grow back and cause recurrence. Conventional chemo is not very good at this. 

 

A drug that preferentially targets and destroys CSCs is the insecticide Ivermectin. It was approved by the FDA who at the time said it was the safest drug they’d ever approved. In the past I chose Retinoic Acid (in acne drug Accutane) for the same job, but it’s hard to find.

 

A 2017 research study in my Ivermectin review showed that while Ivermectin attacked cancer cells (but not as well as Paclitaxel), it preferentially destroyed CSCs and reduced levels of ‘stemness genes’ to a far, far greater extent than the chemo drug.

 

Go to: Off-label Ivermectin attacks cancer in many ways; a Review

 

As regular readers will know, I have covered research on Ivermectin extensively. It was my 'go-to' for Covid prevention and treatment. 

 

The 3-in-1 protocol doses

Although the original clinical approval for Fenbendazole was for intestinal parasites and not for cancer, and it is approved for animal use, the drug has already gone through human clinical trials and so all of the clinical trial work related to toxicity has already been done and Fenbendazole has been deemed safe for human consumption for many years. There can be a liver toxicity issue at high doses so you must monitor your liver enzymes.

There is a ‘Stanford Medicine Protocol’ from five Doctors at Stanford Medical School - all patients had chemo for their cancers. The protocol was typically 444 - 1000 mg Fenbendazole per day 3 days per week;  vitamin E daily 800 mg; Curcumin, 600 mg; CBD oil. All patients became NED (No evidence of disease)within a couple of months. Some patients did take more. You can follow the reference in the FenBen review.

The recommended dose for Mebendazole in humans is 2 x 100 mg daily.

Both Fenbendazole and Mebendazole probably should not be taken continuously over a long period.

The label for the product approval talks of animals not humans. With animals, it is known that there is a likely interaction with salicylanilides like Niclosamide and Dibromsalan, so we suggest you avoid mixing it with either.

Ivermectin was said by the FDA to be the safest drug they'd ever tested, and has a somewhat different action. Some people take 2 mg per 10 kg body weight daily. That rises in Stage 4 cancer to levels of 4 mg per 10 kg.

Research, and experts, suggest the combination drugs should be used for 2-3 months and can be used with chemo.

In my opinion, you should use the drugs with berberine 3 x 500 mg (not metformin because it is inconsistent and also raises cancer-promoting homocysteine levels). You might also use Honokiol to block angiogenesis and Modified Citrus Pectin to block Galectin-3 which causes cancer spread and drug resistance.

Is there any research for the 3-in-1 protocol?

Yes. There is now a peer-reviewed research study where patients with cancer successfully took all three drugs Fenbendazole, Mebendazole and Ivermectin. Experts believe this combination attacks the mitochondrial support for cancer stem cells (1)

All other research references are in the three articles. 

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Sources and References

https://www.canceractive.com/article/is-a%20combination%20of%20fenbendazole%20and%20ivermectin%20a%20real%20cancer%20killer

1. Targeting the mitochondrial stem cell connection in cancer treatment; a hybrid orthomolecular protocol: ilyes Baghli, William Makis, Paul E Marik et al; Journal of Orthomolecular Medicine September 19, 2024

New & Improved Joe Tippens Protocol

The holy grail turbo cancer cure may just be the synergistic combination therapy of Fenbendazole AND Ivermectin as follows:

• Fenbendazole (300mg, 6 days a week) or in the case of severe turbo cancers up to 1 gram.

• Ivermectin (24mg, 7 days a week) or in the case of severe turbo cancers up to 1mg/kg/day (Find a Doctor)

• Bio-Available Curcumin (600mg per day, 2 pills per day 7 days a week).

• Vitamin D (62.5 mcg [2500 IU] seven days a week).

• Tocotrienol and Tocopherol forms (all 8) of Vitamin E (400-800mg per day, 7 days a week). A product called Gamma E by Life Extension (Amazon).

• Removing sugar and processed foods from one’s diet is crucial during this protocol (BMJ 2023), eating a nutritious fresh whole-food diet with fruits and vegetables (BMJ 2024) and a healthy lifestyle with less stress and good quality sleep.

• CBD oil (1-2 droppers full [equal to 25mg per day] under the tongue, 7 days a week)
  CBD-X: The most potent full spectrum organic CBD oil, with 5,000 milligrams of activated cannabinoids and hemp compounds CBD, CBN & CBG per serving.

Please note that this protocol now includes the vital Vitamin D addition, with the one day off for the fenbendazole administration. This protocol represents the most comprehensive and cutting edge repurposed drug and vitamin treatment approach to date.

Adapted from: https://www.2ndsmartestguyintheworld.com/p/15-minutes-with-dr-makis-episode