Top 10 Longevity Leaders Reveal New Secrets (2025)
Key takeaways:
- Personalized protocols are paramount, with each leader tailoring their approach to their unique biology
- Advanced testing and data analysis play a crucial role in optimizing longevity interventions
- Lifestyle factors, particularly sleep optimization and stress management, have gained increased focus
- Emerging technologies and supplements are being integrated into established longevity practices
- Community and knowledge sharing have become essential components of the longevity movement
- The diversity in backgrounds and approaches among these leaders highlights the multifaceted nature of longevity science
10. Julie Gibson Clark

Julie and Amy aren’t the only NOVOS customers making waves. Lil Eskey, a 41-year-old female, is also outperforming Bryan Johnson. In this case, Lil is ranked for her improvement in her pace of biological aging in a before-after NOVOS comparison. Lil slowed her biological pace of aging down from 0.925 per year before NOVOS to just 0.77 after only 6 months of taking NOVOS Core and NOVOS Boost (Julie also had impressive results according to this metric, slowing her pace of aging from 0.765 to 0.65 after 6 months of NOVOS). (source)
And it’s not only women. Men like Rick Chiovarelli, who’s in 7th place on the global leaderboard, have slowed their biological pace of aging by more than 21% to just 0.785 per year.
Web: juliegibsonclark.com
9. Brooke Paulin

Brooke Paulin, the highest-ranking woman on the list, is a dedicated biohacker and entrepreneur based in Chicago, Illinois. She is the Founder and Manager of Biohacker Supply, an online retailer specializing in cutting-edge biohacking equipment. Prior to founding Biohacker Supply, she worked as an independent Biohacking Consultant, offering personalized consultations to clients seeking to enhance their health and performance.
Web: https://biohackersupply.com
8: Daniel Lewis

A rising star in the longevity community, Daniel has gained prominence through his data-driven approach to personalized health optimization. He's known for leveraging advanced testing and analytics to fine-tune his longevity protocol.
7: Siim Land

A 30-yr-old well-known figure in the metabolic health space, Siim has pioneered the integration of continuous glucose monitoring and epigenetic testing into everyday longevity practices. He's author of the book "The Longevity Leap," discussing key factors for optimizing health and lifespan. He's also known for his work on metabolic flexibility and hormesis. (Read More)
6. David Sinclair

A 55-yr-old professor of genetics at Harvard Medical School, Dr. David Sinclair is renowned for his research on aging and the development of therapies to slow down and reverse the aging process. His work on sirtuins and NAD+ has been groundbreaking, and he is the author of the bestselling book “Lifespan: Why We Age—and Why We Don’t Have To.”
You may have come across his published, New York Times best-selling book on aging, “Lifespan: Why We Age – And Why We Don’t Have To”, going deeper into those subjects.
Web: davidasinclair.com
Twitter followers: 471K
5. Joseph Mercola

Twitter followers: more than 400K
4. Bryan Johnson

Web: www.bryanjohnson.com.
Facebook followers: 88 K
3. Rhonda Patrick

Dr Rhonda Patrick with Dr Peter Attia (Instagram)
A biochemist and researcher, Dr. Rhonda Patrick is known for her work on aging, nutrition, and disease prevention. She is the founder of FoundMyFitness, where she shares insights on the latest scientific research on health and longevity.
Twitter Followers: 582K
Frequency 1 post/month
Domain Authority: 51
2. Gary Brecka

54-yr-old renowned human biologist, biohacker, and longevity expert, Gary is dedicated to helping you become the best version of yourself. One of the top biohackers and one of the most controversial minds in human biology. Host of The Ultimate Human Podcast, Gary’s mission is to empower you with the knowledge and tools to achieve peak performance and vitality.
1. Peter Attia

A 52-yr-old physician focusing on the applied science of longevity, Dr. Peter Attia explores the most effective ways to increase lifespan and healthspan. He hosts “The Peter Attia Drive” podcast, discussing topics related to health, performance, and longevity.
Dr Peter Attia explores strategies and tactics to increase lifespan, health span, and well-being, and optimize cognitive, physical, and emotional health. Peter is a physician focusing on the applied science of longevity. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (how long you live), while simultaneously improving healthspan (the quality of your life).
Personalization: The cornerstone of success
Advanced testing and data analysis
Emerging technologies and supplements
The top leaders are early adopters of cutting-edge technologies and novel supplements:• Senolytic Therapies: There's growing interest in interventions targeting senescent cells, with some leaders experimenting with both natural and pharmaceutical senolytic compounds.
• Exosome Treatments: A few top performers are exploring the potential of exosome therapies for cellular rejuvenation.
• Novel NAD+ Precursors: Beyond NMN and NR, some leaders are testing new compounds aimed at boosting NAD+ levels more effectively.
The power of Community and Knowledge sharing
Siim Land hosts a weekly "Longevity Roundtable" where he invites fellow biohackers to share their latest experiments and results. Bryan Johnson has expanded his open-source approach, providing detailed protocols and data analysis tools to the public.
This collaborative spirit is accelerating the pace of discovery and allowing for rapid iteration of longevity strategies across the community.
Conclusion: The road ahead
Analyzing the strategies of the top 10 longevity leaders reveals a field advancing at an unprecedented pace. The integration of advanced testing, personalized protocols, and cutting-edge technologies—combined with a renewed emphasis on foundational lifestyle practices—is redefining the boundaries of human healthspan.
Despite varied interventions, these leaders share a commitment to self-experimentation, data-driven decision-making, and open knowledge sharing. This collaborative approach is likely to continue driving innovations in longevity science, bringing us closer to the goal of significantly extending healthspans for all.
Their journey offers both inspiration and a practical roadmap for optimizing health and longevity. If you're inspired to begin your own longevity journey, start by assessing your current health and identifying areas for improvement. Consulting a longevity specialist can help you create a personalized plan aligned with your goals and biology. Remember, small, consistent changes can lead to profound improvements in healthspan over time.
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