12 Best Natural Alternatives to Ozempic for Weight Loss (2025)

There are natural alternatives to Ozempic like berberine, turmeric and psyllium husk.

Ozempic is a popular weight-loss medication that helps curb appetite and induces various metabolic changes linked to improved weight management.

However, this injectable medication is costly, and its long-term use may lead to serious health issues, including thyroid cancer, muscle mass loss, and kidney damage.

The 2023 report from the World Obesity Federation estimates that the economic impact of overweight and obesity will surpass $4.3 trillion annually by 2035. In the U.S., the CDC reports the prevalence of obesity in adults was 41.9% measured from 2017 to March 2020. This represented an increase from 30.5% from 1999 to 2000. The estimated annual medical costs were roughly $173 billion in 2019 dollars.

Prescriptions for semaglutide have doubled since mid-2021, rising to more than 1.2 million. In April 2023, a spokesperson for Novo Nordisk, maker of semaglutide, said the drugs are now available in pharmacies nationwide. Semaglutide is sold under the name Ozempic as a diabetes drug and under the name Wegovy as a weight loss prescription drug.

Wegovy has recently boomed in popularity for its use to help people lose weight... fast. Celebrities and public figures have admitted they're taking it. Instagram influencers are showing off remarkable before and after photos. It's been called "TikTok's favorite weight loss drug." As one doctor said, "we haven't seen a prescription drug with this much cocktail and dinner chatter since Viagra came to the market."

Discover natural alternatives to Ozempic and learn how to make beneficial dietary changes to achieve and maintain a healthy body weight without needing pharmaceutical drugs.

What is Ozempic?

Ozempic is a brand name for the generic medication called semaglutide, which the FDA approved in 2017. Ozempic is in a class of medications called GLP-1 receptor agonists. Ozempic and Wegovy are both semaglutide, but Wegovy, which is approved for weight management, is a higher dose.

GLP-1 receptors in your pancreas help increase insulin secretion while reducing the secretion of glucagon, a hormone that raises blood sugar levels. GLP-1 receptor agonists activate these receptors to help lower blood sugar levels.

Ozempic is a non-insulin injectable medication for type 2 diabetes. The typical starting dose of Ozempic is 0.25 milligrams once weekly for four weeks, then 0.5 milligrams weekly for at least four weeks. If blood sugar targets aren’t being met with 0.5 milligrams weekly, the dose can gradually be increased to a maximum of 2 milligrams weekly.

Ozempic may promote weight loss because it helps reduce hunger and promotes fullness by slowing stomach emptying (2). Slowed stomach emptying can also reduce spikes in blood sugar levels.

Semaglutide is sold under the name Ozempic as a diabetes drug and under the name Wegovy as a weight loss prescription drug.

According to GoodRx, a month's prescription of Wegovy costs from $1,300 to $1,500, depending on where you purchase it.

The GLP-1 Paradox

Ozempic does indeed provide a hormone that your body desperately needs, GLP-1 is a hormone that is primarily produced by specialized cells in your colon called enteroendocrine L cells. These cells are scattered throughout your intestines, but they're most concentrated in your colon.

But unlike Ozempic that gives you continuous GLP-1, these L cells produce GLP-17 in response to the nutrients you eat, especially carbohydrates and fats. GLP-1 plays a crucial role in regulating your blood sugar. It stimulates insulin secretion, inhibits glucagon release, and slows down how quickly your stomach empties (Int J Mol Sci. 2024).

The effects of these gut hormones on your appetite and food intake are profound. GLP-1, whether naturally released or administered as a medication, has been consistently shown to reduce food intake in both animals and humans.

This is why GLP-1 receptor agonists are now used as treatments for obesity and Type 2 diabetes. The effects of GIP on appetite are less clear and somewhat controversial, with some studies suggesting it might increase food intake. However, recent research has shown promise in combining GLP-1 and GIP agonists for even greater weight loss and metabolic benefits (Nutrients. 2021).

The mechanisms by which these hormones influence your eating behavior are complex. They involve both direct effects on your digestive system — slowing down stomach emptying and intestinal movement — and interactions with your nervous system. GLP-1, for example, can activate nerve endings in your intestine that send signals to your brain, influencing areas involved in appetite control and food reward.

It can also act directly on your brain after crossing the blood-brain barrier. This intricate system of nutrient sensing and hormone release in your gut plays a crucial role in regulating your appetite, metabolism, and overall health, underscoring the truth in the old saying that you are what you eat.

Ozempic is mimicking a natural process in your body, but at what cost? They're not addressing the root cause of why your L cells might not be producing enough GLP-1 in the first place. Instead, they're creating a dependency on an external source of this hormone.

And let's not forget the price tag — $20,000 per year for something your body should be producing naturally if given the right conditions. It's another example of how the pharmaceutical industry is profiting from our metabolic dysfunction rather than helping us address the underlying issues.

What you should be asking is: why aren't your L cells functioning properly? What in your diet and lifestyle is disrupting this natural process? But of course, there's no profit in teaching you how to eat and live in a way that supports your natural GLP-1 production. It's much more lucrative to sell you a synthetic version for the rest of your life.

We're not treating the cause; we're managing symptoms at an exorbitant cost, both financially and in terms of our long-term health.

Natural alternatives to Ozempic

Because of Ozempic’s high cost, risk of side effects, and potential long-term health concerns, many individuals are seeking natural alternatives to pharmaceutical weight loss drugs.

Ozempic works by mimicking GLP-1. Interestingly, various plant compounds naturally stimulate GLP-1 release and enhance its activity in the body.

Here are twelve natural alternatives to Ozempic.

1. Berberine

Berberine, often called natural Ozempic, is a plant pigment found in goldenseal, barberry, Oregon grape, and tree turmeric. For centuries, berberine has been used to promote metabolic balance in traditional Ayurvedic and Chinese medicine.

 

Berberine is a compound we can find in some plants like European barberry, goldenseal, goldthread, Oregon grape, Phellodendron, and tree turmeric. Berberine is a natural alternative for treating insulin resistance and high blood sugar.

Berberine has received a lot of media attention as it gains momentum on social media as a weight loss supplement. Berberine is a compound that's extracted from goldenseal, barberry, Oregon grape and tree turmeric. It has traditionally been used in Ayurvedic medicine and traditional Chinese medicine for nearly 2,000 years.

A 2024 research published in the Archives of Biochemistry and Physiology found that berberine can directly induce GLP-1 release in the gastrointestinal tract.

A 2022 systematic review of the literature evaluated randomized controlled trials of adults who were given berberine supplementation. The pooled results demonstrated that berberine did reduce insulin levels and the optimal dose given in these studies was 1 gram per day. The data from the systematic review in 2022 showed that berberine could help improve insulin sensitivity and may therefore influence weight loss.

According to another small study on people with metabolic syndrome (a condition that can lead to type 2 diabetes), berberine improved insulin sensitivity and reduced participants’ waist circumference (5).

 
Waist circumference is associated with insulin resistance. Therefore, reducing waist size can indicate improving insulin sensitivity and lower blood sugar levels.

A pilot study directly compared berberine and metformin (a popular pill used to treat diabetes) for their ability to help treat symptoms of type 2 diabetes (6).

The researchers found that berberine produced identical results as metformin in improving blood glucose metabolism. Berberine may help promote weight loss by improving insulin resistance.

You can take berberine in supplement form at a dose of up to 1.5 grams daily. However, the studies on berberine tend to be six months or less, so it’s not as clear how safe it is to take the maximum dose indefinitely.

According to many studies, berberine is well-tolerated. However, it can interfere with some medications, including oral chemotherapy, high blood pressure medications, blood thinners, cholesterol medications, immunosuppressive drugs, and pharmaceutical diabetes treatments (US News). Women who are pregnant or breastfeeding should avoid berberine. Other side effects can include constipation, diarrhea, low blood sugar, nausea and vomiting.

Like metformin, berberine can also activate AMPK*. However, berberine is an alkaloid, which often are quite toxic compounds.

*AMP-activated protein kinase (AMPK) is a crucial cellular energy sensor. Once activated by falling energy status, it promotes ATP production by increasing the activity or expression of proteins involved in catabolism while conserving ATP by switching off biosynthetic pathways. (source)

In our opinion, there are not enough studies showing that long-term berberine intake is safe, or even better, that berberine can extend lifespan in different organisms.

Related: Best Berberine Supplements

2. Turmeric for weight loss

Most famously sprinkled in Indian dishes, turmeric is more than just colorful. Curcumin, a natural anti-inflammatory compound in turmeric, shows promise in helping fight diabetes, especially given its efficacy in reducing blood sugar and fat levels in animal studies.

A 2019 meta-analysis of 21 randomized controlled trials involving 1,604 participants has affirmed the weight loss potential of curcumin. Curcumin intake was found to significantly lower BMI, weight, and waist circumference. It also is shown to decrease leptin levels—a hormone linked to fat storage—while elevating adiponectin levels, which is beneficial for metabolism.

Recommended: Bioavailable Curcumin

3. Caffeine and Slimming Coffee Products

Caffeine is the most commonly consumed psychoactive substance in the world (Source).

It is found naturally in coffee, green tea and dark chocolate, and added to many processed foods and beverages.

Caffeine is a well known metabolism booster, and is often added to commercial weight loss supplements.

How it works: Short-term studies have shown that caffeine can boost metabolism by 3-11%, and increase fat burning by up to 29% (Source, Source, source, source).

Effectiveness: There are also some studies showing that caffeine can cause modest weight loss in humans (Source, Source).

Side effects: In some people, high amounts of caffeine can cause anxiety, insomnia, jitteriness, irritability, nausea, diarrhea and other symptoms. Caffeine is also addictive and can reduce the quality of your sleep.

The best sources of caffeine are quality coffee and green tea, which also have antioxidants and other health benefits.

The coffee diet is a relatively new diet plan that’s rapidly gaining popularity. It involves drinking several cups of coffee per day while restricting your calorie intake. Some people have reported short-term weight loss success with the diet. However, it has some significant downsides.

The coffee diet encourages you to drink at least 3 cups (720 ml) of coffee per day while restricting calorie intake.

Though it may result in short-term weight loss, it’s not a healthy diet in the long run.

It can lead to weight regain and adverse effects from excessive caffeine intake. For safe and healthy weight loss, you should avoid restrictive programs, such as the coffee diet, in favor of more sustainable plans.

What about caffeine supplements and slimming coffee products? There are many coffee supplements and coffee slimming products available online. If you are already drinking a cup or two cups of coffee a day, it may not be necessary for you to take caffeine supplements or slimming coffee products. However, if you do intend to take them, do not go overboard as they may lead to side effects if taken excessively.

As mentioned above, it could be useful in the short term but the long term solution is to have a sustainable and healthy weight loss program.

4. Quercetin with Bromelain for Weight Loss

Some people believe that consuming quercetin, whether in foods or as a natural supplement, can help promote weight loss. However, there have been mixed reviews and conclusions on the effects of quercetin for weight loss and its effect on the expression of certain genes. 

These inconsistent findings from the studies maybe are due to the difference in the range of fitness of the subjects, differences in research design, different methods in the preparation of quercetin extract, etc. In order to assist you in doing your own research, let's dive into some relevant studies and reviews.

Matthew Solan, author of Doctor’s Detox Diet reports that quercetin can mimic the effect of calorie restriction. However, it shows to have a greater effect on weight loss when combined with other fat-fighting phytochemicals such as resveratrol and genistein.

Another interesting side effect of quercetin, as reported by MuscularDevelopment.com, is that quercetin may offer some of the same psychostimulant properties of caffeine. Therefore, consuming it may help people increase their activity throughout the day and delay fatigue. Plus, this can lead to expending more energy during workouts, thus burning more calories.

Dr Josh Axe also adds that some athletic supplements contain quercetin because some people believe that is increases endurance and athletic performance.

In another study, a combination of Quercetin along with Resveratrol inhibited the formation of mature fat cells, which subsequently resulted in weight loss. Quercetin increases the secretion of the enzyme, triglyceride lipase that breaks down fat, thus aiding in weight loss.

It was also discovered that consumption of 500 mg of quercetin twice a day increased the VO2 max (the maximum amount of oxygen that is utilised by an individual) in untrained individuals as a result of an increase in mitochondrial biogenesis. This enhancement in fitness without exercise training can be used in disease prevention such as obesity.

Since bromelain can help to improve the absorption of quercetin, there should be greater benefit when quercetin and bromelain are taken together.

5. Green Tea Extract

Green tea extract is a popular ingredient in many weight loss supplements.

This is because numerous studies have shown the main antioxidant in it, EGCG, to aid fat burning.

How it works: Green tea extract is believed to increase the activity of norepinephrine, a hormone that helps you burn fat (source).

Effectiveness: Many human studies have shown that green tea extract can increase fat burning and cause fat loss, especially in the belly area (Source, Source, Source, source).

Side effects: Green tea extract is generally well tolerated. It does contain some caffeine, and may cause symptoms in people who are caffeine sensitive. However, Green tea extract supplements have been linked to rare cases of liver damage. Green tea extracts might make liver disease worse. Talk to your doctor before taking a green tea extract. Tell your doctor if you have signs of liver damage such as yellowing skin, dark urine, or abdominal pain. Keep in mind that drinking green tea as a beverage is normal amounts is still probably safe. But despite all the health perks that come with that cup, downing too many in a day can actually make some people sick. This is exactly what happened to one 16-year-old girl after she started slurping down three cups of Chinese herbal green tea a day over three months as part of a weight loss plan. She showed up at the hospital with what she thought was a severe UTI, only to find it was actual this type of herb-induced hepatitis. 

Additionally, all of the health benefits of drinking green tea should apply to green tea extract as well.

6. Niacinamide for Weight Loss

Niacinamide is a precursor to NAD+ (nicotinamide adenine dinucleotide), (a vital signaling molecule that’s believed to play an important role in longevity.

Writing in The Journal of Nutritional Biochemistry (2022), researchers from Tsinghua University, Beijing, revealed that NAM reprograms adipose cellular metabolism and increases mitochondrial biogenesis to ameliorate obesity. In a study on obese mice, NAM supplementation led to significant reductions in fat mass and improved glucose tolerance, while increasing mitochondrial biogenesis in fat tissue.

Read More: Niacinamide and Weight Loss: Niacinamide Has Striking Antiobesity Effects

7. Psyllium Husk

Ozempic shortage, the high cost and potential side effects have some turning to natural, over-the counter alternatives to lose weight, including psyllium husk supplements. It’s the main ingredient in Metamucil.

A 2023 meta-analysis found that, on average, 10.8 grams* of psyllium husk per day, taken before meals, led to a 2.1-kilogram weight loss and a 2.2-centimeter reduction in waist circumference among people with overweight and obesity after nearly five months. This weight loss is likely due to reduced insulin resistance from improved blood sugar control and reduced calorie intake from increased feelings of fullness.

Psyllium husk is affordable, accessible and available without a prescription. But can it really promote significant weight loss?

News4 asked Dr. Michele Arthurs, an obesity medicine physician with Kaiser Permanente, what you need to know.

Arthurs recommended combining a high-fiber diet and lifestyle changes before considering taking any prescription medication to lose weight.

“Fiber is a starting point, well before medication is used,” she said. “It helps us to feel fuller longer when we have sources of fiber in our diet.”

While psyllium husk is primarily used to help improve digestive health, research shows it also can lower cholesterol, control blood sugar levels and help people lose weight.

*Note: 1 teaspoon - 5 grams

8. Vitamin D for Weight Loss

A 2011 study in The Journal of Investigative Dermatology revealed a remarkable fact of metabolism: The exposure of human skin to UV light results in increased subcutaneous fat metabolism. While subcutaneous fat, unlike visceral fat, is not considered a risk factor for cardiovascular disease, it is known that a deficiency of one of sunlight's best known beneficial byproducts, vitamin D, is associated with greater visceral fat (Seo 2012). 

Also, there is a solid body of research showing that vitamin D deficiency is linked to obesity, with 9 such studies on GreenMedInfo obesity research page. One of them, titled "Association of plasma vitamin D levels with adiposity in Hispanic and African Americans," and which was published in the journal Anticancer Research in 2005, found that vitamin D levels were inversely associated with adiposity in Hispanics and African-Americans, including abdominal obesity (Young 2009).

9. Glucomannan

Glucomannan is a type of fiber derived from an Asian plant called Konjac.

How it works: Glucomannan absorbs water and becomes gel-like. It "sits" in your gut and promotes a feeling of fullness, helping you eat fewer calories (source).

Effectiveness: Three human studies showed that glucomannan, combined with a healthy diet, can help people lose 8-10 pounds (3.6-4.5 kg) of weight in 5 weeks (Source).

Other benefits: Glucomannan is a fiber that can feed the friendly bacteria in the intestine. It can also lower blood sugar, blood cholesterol and triglycerides, and is very effective against constipation (Source, Source, Source).

Side effects: It can cause bloating, flatulence and soft stools, and can interfere with some oral medications if taken at the same time.

10. Garcinia Cambogia

Garcinia cambogia is a tropical fruit from South-East Asia which is also known as Malabar Tamarind or Brindleberry. 

The fruit became hugely popular after its premiere on The Dr Oz Show; naming garcinia cambogia as the “the newest breakthrough in weight management”. However, in June 2014, Dr. Oz was chided for making unwarranted claims about garcinia cambogia and other products in an appearance before the Senate Subcommittee on Consumer Protection, Product Safety, Insurance, and Data Security.

Recommended dosages can vary between brands. When it comes to a recommended dose, most sources provide the recommended dose of HCA rather than garcinia cambogia itself. According to ConsumerLab.com, the recommended dose of garcinia cambogia is 900 mg to 1,500 mg of HCA a day. This is consistent with doses used in a number of studies.

It is always best to follow the dosage instructions on the label.

Studies have only tested these supplements for up to 12 weeks at a time. Therefore, it may be a good idea to take a few weeks off every three months or so.

11. Lactobacillus Gasseri (Probiotic) for Weight Loss

Lactobacillus gasseri, of all the probiotic bacteria examined so far, shows some of the most promising weight-loss effects. It has been shown in numerous animal experiments that it has anti-obesity properties.

In addition, studies in adults have also shown encouraging results. According to a study, probiotic Lactobacillus gasseri showed lowering effects on abdominal adiposity, body weight and other measures in adults with obese tendencies.

Another study was conducted using 210 healthy Japanese adults with significant amounts of belly fat who were asked to consume Lactobacillus gasseri for 12 weeks.

As result, BMI, waist and hip circumferences, and body fat mass were significantly decreased. Moreover, belly fat was also reduced by 8.5%. However, this study also suggest that constant consumption might be needed to maintain the effect.

12. Chlorella and Spirulina for Weight Loss

Chlorella Benefits for Weight Loss

Chlorella may have an effect on how fat cells behave in the body, therefore it may help with weight loss.

Chlorella appears to have good health benefits on slightly hypercholesterolemic subjects’ blood lipid profiles, at least in part by improving serum carotenoid profiles. According to one study, the possible effects of Chlorella on serum lipids might be caused by a suppression of intestinal lipid absorption attributable to increased levels of highly polar carotenoids from Chlorella. However, further studies are required to determine this finding.

Spirulina Benefits for Weight Loss

According to a study, spirulina platensis, as a supplemental therapy, may help with adherence to restricted calorie diet, weight loss management, and triglyceride reduction via modulating anti-inflammatory pathways.

Another study found that consuming Spirulina maxima on a regular basis for three months improves BMI and weight. Furthermore, it improves blood pressure and endothelial function in overweight patients with hypertension.

Ozempic Side Effects

Some of the most common Ozempic side effects include:

• Gastrointestinal symptoms like upset stomach (nausea or vomiting), stomach pain, loss of appetite, heartburn, burping, gas, and bloating
• Diarrhea or constipation
• Headache
• Dizziness
• Ozempic-related tiredness (fatigue)
• Injection site pain
• Low blood sugar (especially if you’re taking another diabetes medication like insulin or sulfonylureas)

According to Dr. Peter Attia, “Not all weight loss is healthy.” Shedding excess fat mass is certainly a positive, but “shedding lean mass—which includes muscle and bone—is associated with poorer health trajectories and reduced lifespan.” Ozempic, a once-weekly injectable medication, appears to result in the shedding of lean mass, according to the respected medical professional. Moreover, this is an injection that needs to be taken for the entirety of one’s life. If an individual stops taking the medication, there is a very high chance that they will put all the weight back on.

Diet and Exercise: Lower Your Blood Sugar

Patients may want to look at over-the-counter (OTC) drugs or vitamins for a solution to help lower their blood sugar. However, according to the American Diabetes Association (ADA), when considering a vitamin or supplement, there is a possibility of drug interactions and potential effects on blood sugar (for example, causing blood sugar to get too low or too high). Some supplements can have drug interactions or cause troublesome side effects. The ADA notes that “research on many supplements is inconclusive.” Consult your healthcare provider before adding any vitamins or supplements to your regimen.

Making some diet and lifestyle modifications can help control blood sugar. However, dietary and lifestyle changes are not a replacement for your prescription medication. Ask your healthcare provider which diet plan is best for you.

A healthy diet should include a variety of fruits and vegetables, lean protein, whole grains, and low-fat dairy.

Exercise can help to control blood sugar as well. Talk to your healthcare provider if you need help determining what type of exercise will be safe and effective for you. Be sure to discuss when to test blood sugar in relation to exercise—and how to avoid and treat hypoglycemia (low blood sugar). You can use this chart as a guideline but show it to your healthcare provider to make sure it is appropriate for you.

Related: Fasting: The Science Behind

 

Key Takeaways

Ozempic has become a popular weight loss drug. However, it’s a costly medication that’s associated with side effects and long-term health risks, including thyroid cancer and kidney damage.

Natural alternatives to Ozempic, such as berberine and turmeric (curcumin), have been shown to offer comparable metabolic and weight loss benefits to pharmaceutical drugs, with a lower risk of adverse effects.

If you've tried all the strategies mentioned and haven't seen progress, it may be time to seek help from a medical professional. Consulting a doctor can provide valuable insights and personalized guidance tailored to your specific weight loss challenges.

It's essential to assess whether your weight loss goals are realistic and achievable within a healthy timeframe. Unrealistic expectations for rapid weight loss can lead to frustration or unhealthy practices. A doctor can help you set attainable goals and develop a sustainable plan that aligns with your health needs.

Speaking with a doctor about your weight loss struggles can also help identify any underlying medical conditions that may be hindering your progress. Medical professionals can conduct assessments, perform necessary tests, and provide expert advice on the best way forward.

Weight loss is a gradual process that requires patience, consistency, and a balanced approach. While slimming products may offer some benefits, they should be combined with other healthy habits like reducing carb and sugar intake and staying active. If you’re using a slimming product, always follow the recommended dosage—taking more won’t necessarily make it more effective and may even be harmful.

Rather than setting overly ambitious short-term goals, consider breaking your weight loss journey into smaller, more manageable milestones over a longer period. Seeking support from a registered dietitian, personal trainer, or support group can also be beneficial, providing guidance, motivation, and accountability.

Most importantly, approach your weight loss journey with a positive mindset. Be patient with yourself, and celebrate even small victories along the way. With the right support and a well-rounded approach, you can make steady progress toward your weight loss goals in a healthy and sustainable way.

Sources and References:

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2. Marathe CS, Rayner CK, Jones KL, Horowitz M. Relationships between gastric emptying, postprandial glycemia, and incretin hormones. Diabetes Care. 2013. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631884/
3. Brunton S. GLP-1 receptor agonists vs. DPP-4 inhibitors for type 2 diabetes: is one approach more successful or preferable than the other? Int J Clin Pract. 2014. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238422/
4. Tsampasian V, Baral R, Chattopadhyay R, Debski M, Joshi SS, Reinhold J, Dweck MR, Garg P, Vassiliou VS. The Role of SGLT2 Inhibitors in Heart Failure: A Systematic Review and Meta-Analysis. Cardiol Res Pract. 2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397556/
5. Pérez-Rubio KG, González-Ortiz M, Martínez-Abundis E, Robles-Cervantes JA, Espinel-Bermúdez MC. Effect of berberine administration on metabolic syndrome, insulin sensitivity, and insulin secretion. Metab Syndr Relat Disord. 2013. https://pubmed.ncbi.nlm.nih.gov/23808999/
6. Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2410097/
7. Veronese N, Watutantrige-Fernando S, Luchini C, Solmi M, Sartore G, Sergi G, Manzato E, Barbagallo M, Maggi S, Stubbs B. Effect of magnesium supplementation on glucose metabolism in people with or at risk of diabetes: a systematic review and meta-analysis of double-blind randomized controlled trials. Eur J Clin Nutr. 2016. https://pubmed.ncbi.nlm.nih.gov/27530471/
8. de Valk HW. Magnesium in diabetes mellitus. Neth J Med. 1999. https://pubmed.ncbi.nlm.nih.gov/10218382/
9. Radha MH, Laxmipriya NP. Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. J Tradit Complement Med. 2015. https://www.sciencedirect.com/science/article/pii/S2225411014000078 
10. Rajasekaran S, Ravi K, Sivagnanam K, Subramanian S. Beneficial effects of aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes. Clin Exp Pharmacol Physiol. 2006. ​​https://pubmed.ncbi.nlm.nih.gov/16487267/ 
11. Kidney and Gastro Issues Linked to Ozempic
12. Booming Demand for Obesity Pill to Solve Junk Food Problem
13. Ozempic Use Now Linked to ‘Deflated’ Breasts
14. Thyroid Cancer Concerns Raised Regarding Active Ingredient in Popular Drugs Ozempic and Wegovy
15. Over 200 Cases of Suicidal Thoughts After Taking Weight Loss Drugs: Reuters Analysis
16. US FDA Recommends Against the Continued Use of Meridia (sibutramine)
17. Compounded versions of Ozempic and Wegovy under federal scrutiny

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