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Creatine for Physical and Mental Health 2025

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The powerful benefits of creatine are now being widely recognized, with experts even recommending it as the go-to fitness supplement that can give you “the best bang for your buck.” (1) Apart from enhancing athletic performance, studies have also credited it for helping build body mass and decrease body fat percentage when combined with exercise. (2) But even if you’re not a bodybuilder or professional athlete, you can benefit from increasing your creatine intake and optimizing your levels. Let’s take a closer look at what creatine can do for you. What Is Creatine? Although creatine is often referred to as an “amino acid," it isn’t one of the 20 amino acids that are considered the building blocks of protein. Rather, creatine is a nitrogenous organic acid made from three true amino acids, namely glycine, arginine and methionine. 3 , 4 Your body naturally produces creatine — 95% of your body’s creatine supply is found in your skeletal muscle while 5% is in your brain. It supplies en...

How to Help Prevent and Treat Alzheimer’s Disease - Dr Dale Bredesen

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In this video (below), I interview repeat guest Dr. Dale Bredesen, a neurologist specializing in the treatment of Alzheimer’s. In 2014, he published a paper1 demonstrating the power of lifestyle choices for the prevention and treatment of this tragic condition. By leveraging 36 healthy lifestyle parameters, he was able to reverse Alzheimer’s in 9 out of 10 patients. Randomized Trial Launch For starters, his team has published another proof-of-concept paper and are now launching a randomized, controlled trial at six sites: Hollywood, Florida; Nashville, Tennessee; Cleveland, Ohio; and Sacramento, Oakland and San Francisco in California. Biological aging, brain aging and epigenetics will be assessed in this trial, using newer blood tests that weren’t available even a few years ago, including phospho-tau 181, phospho-tau 217, A-beta 42 to 40 ratio, glial fibrillary acidic protein (GFAP) and neurofilament light polypeptide (NF-L).  “A couple of these are not commercially available ye...

Not All Carbs Are Created Equal: What You Need to Know (2025)

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This interview (below) features repeat guest Georgi Dinkov who is a virtual firehose of information and an expert on the work of the late Ray Peat (1,2) Ph.D., an author and pioneer in nutrition, bioenergetic medicine, environmental factors and regenerative processes. Some of the information in this interview will challenge some of your long held views as it did mine. We all have conformational biases and I encourage you to let yours go for awhile and consider the possibility that some of this information might be true for you and others. This is among the best interviews I’ve done in years, and we take deep dives into a wide variety of topics. The full interview is over three hours long, so I’m dividing it into two parts. This is Part 1. This year, on a near-daily basis, I’ve been listening to Dinkov’s podcast for two to three hours at a stretch, and I sometimes repeat them two or three times, because each episode is just so chockful of information. If you want to get a deep understan...

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