Mebendazole for Thyroid Cancer: 2020 paper by Johns Hopkins University

MEBENDAZOLE and Thyroid Cancer - Inhibits tumor growth and prevents lung metastasis - shocking new Johns Hopkins research on Fenbendazole's sister drug.

In a 2020 paper by Johns Hopkins researchers led by Tara Williamson, Mebendazole halted Anaplastic Thyroid Cancer and shrunk Papillary thyroid tumors.

For those of you who know, Anaplastic Thyroid Cancer is one of the most aggressive cancers that exist.

"The purpose of this study was to determine if mebendazole could be repurposed to effectively treat thyroid cancer, in particular before metastasis." "In vitro, mebendazole potently inhibited the growth of a panel of human papillary and anaplastic thyroid cancer cells" "In aggressive anaplastic thyroid cancer cells, mebendazole significantly repressed migratory and invasive potential" "In vivo, mebendazole treatment resulted in significant papillary thyroid tumor regression and growth arrest of anaplastic tumors, with treated tumors displaying reduced expression of the proliferation marker Ki67 and less vascular epithelium" "Most importantly, daily oral mebendazole prevented established thyroid tumors from metastasizing to the lung" "Given the low toxicity, this novel preclinical study of mebendazole has promising therapeutic implications for patients with treatment refractory papillary or anaplastic thyroid cancer." As Dr William Makis continue to do Cancer Consultations, he has been approached by a number of Thyroid Cancer patients who have run out of options. Seeing the tumors shrink in mice like this is something you don't see everyday and is shocking and impressive.

  While Fenbendazole and Ivermectin get all the glory for being the top repurposed drugs for Cancer today (including COVID-19 mRNA Vaccine Induced Turbo Cancers), it's important to remember that Fenbendazole's sister drug Mebendazole also has a vast body of preclinical research that is, in many cases (including this one), absolutely stunning.

Are there more related studies? For more Fenbendazole case series, check out Fenbendazole Cancer Case Series.

Notes:

No single drug is a miracle cure for all cancers. Taking a particular drug as a stand alone strategy cannot replace an unhealthy lifestyle i.e. heavy smoker, alcoholic, a very stressful and non-active lifestyle, overweight and obesity. All these cancer promoting factors need to change.

The best way to fight cancer is to utilise a menu of strategies by maintaining good health, like from eating a nutritious whole-food diet with lots of fruits and vegetables, avoid ultra processed foods and a healthy lifestyle. Each strategy might produce an incremental improvement in results for some cancers when added to existing treatment regimens.

Everyone’s situation is different, however, it is important to arm yourself with medical knowledge that cancer doctors (Oncologists) may simply not give you.

Whether you’re living with cancer or a survivor, talk to your doctor to determine the best treatment for you.

Disclaimers: 

• Please do not consider this guide as personal medical advice, but as a recommendation for use by professional providers. Consult with your doctor and discuss with her/him. 
• Our aim here isn't to replace your doctors' advice. It is intended as a sharing of knowledge and information. Do take note that most treatments are not 100% protective or curative against cancer. It's a continuous struggle between the immune system and the cancer cells. Cancer treatments are meant to assist the immune system in this battle.
• Cancer treatment should be part of a multi-modal approach in order to provide the best possible outcome. Diet and lifestyle changes are meant to run alongside conventional treatment. They are complementary, not alternative. That said, there is no miracle diet or treatment that can cure all cancers.

Find Integrative Oncologists in USA, Mexico, Europe or Asia

While the potential anti-cancer properties of fenbendazole are intriguing, it’s crucial to approach with caution.

Consulting with an integrative healthcare expert is key to crafting a Fenbendazole protocol tailored to your unique health requirements. 

To find integrative oncologists, check out "find integrative oncologists".

Updated Joe Tippens Protocol

The following is a modernized version of the original Joe Tippens protocol, updated to incorporate the ivermectin- and mebendazole-based regimen published in the Journal of Orthomolecular Medicine (2024). It combines repurposed antiparasitic drugs with evidence-supported nutraceuticals:

• Ivermectin (24 mg, 6 days a week) or in the case of severe aggressive cancers up to 1mg/kg/day.
• Mebendazole (Dose of 200 - 400 mg/day) or Fenbendazole, commonly taken at 300 mg for six days a week, with doses increasing to up to 1 gram in cases of aggressive cancers.
• Most berberine and curcumin supplements have low oral bioavailability. UltraCur Curcumin Complex and Pure Encapsulations Berberine UltraSorb are specially formulated for optimal absorption.
• Bio-Available Curcumin (600 mg per day, 7 days a week). 
• Enhanced absorption Berberine (500 mg per day) to starve your cancer of sugar.
• Diet and Lifestyle: 
• A 2026 study (American Association for Cancer Research), linked Ultra-Processed Foods to Reduced Survival after Cancer. Sugar, starch, saturated fat packed into ultra-processed food not only associated with obesity, diabetes, and heart disease, it also worsens cancer prognosis.
• Another 2026 study published in The BMJ examined how everyday exposure to food preservatives influences cancer risk. The findings were clear — people who consumed more preservatives had higher rates of overall cancer and breast cancer. The findings support recommendations for consumers to favour freshly made, minimally processed foods.
• Another 2026 findings published in Nature Communications, insulin resistance has been linked to a 25% higher risk of 12 different types of cancer. Insulin resistance is often caused by obesity and its associated chronic inflammation. Both diabetes and obesity are associated with a higher risk of cancer. 
• Adopt a whole-food diet and avoid ultra-processed foods, as recommended by the BMJ 2024 guidelines. 
• Eliminate sugar consumption as supported by the BMJ 2023 umbrella review, which recommends reducing free and added sugars to below 25 g/day and limiting sugar-sweetened beverages to less than one serving per week to reduce adverse health effects. 
• Additionally, prioritise adequate sleep and effective stress management to support overall health.

*Notes:

• Please note that this protocol now includes the vital Vitamin D addition, with the one day off for the fenbendazole administration. This protocol represents the most comprehensive and cutting edge repurposed drug and vitamin treatment approach to date.
• Vitamin E: Removed from the protocol (Joe Tippens, July 22, 2020) due to interactions (e.g., with blood thinners).

References:

• Dr Peter McCullough: How to Detox Spike Protein from Body
• FLCCC I-Recover Protocol (Post-Vaccine Treatment Protocol)
• Top 10 Repurposed Drugs and Metabolic Interventions for Cancer Treatment
• Can Diet and Lifestyle influence your Risk of getting Cancer?
• Mebendazole vs fenbendazole for cancer

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