Omega XL Reviews 2023: Pros and Cons

Omega XL is a pain and inflammation supplement said to be 22x more potent than a regular omega 3 fish capsule without the side effects. The company touts that the special ingredient that sets it apart from a plain old Omega 3 capsule is the ingredient called Perna Canalicilus, otherwise known as PCSO-524.

Within this ingredient, there are over 30 fatty acids found just from the lipped mussel extract out of New Zealand. [R] The company that creates this product is called Great HealthWorks, and they are located out of Fort Lauderdale, FL. The return policy for all of their products including Omega XL says,

You have thirty (30) days from the date you receive your product to request a refund of the purchase price. If you purchased a bottle of OmegaXL® on the Great HealthWorks’ online store, Great HealthWorks’ will honor the OmegaXL® 90 day money back guarantee.” [R]

How Does Omega XL Work?

In each bottle, you will find a total of 60 soft gel capsules, and the instructions for taking those capsules is as follows: “Take 2 soft gel capsules 1-3 times per day, preferably with food.” [Amazon] There is said to be no fishy aftertaste when taking the small capsules, and they claim the product is 89% more effective than standard fish oil capsules at reducing joint pain in the body. 

Other than just taking the capsule as directed there is nothing more to this supplement. It is not marketed for weight loss of any kind, but rather just for reducing inflammation in the body more effectively than your normal omega 3 capsules. For one bottle which lasts anywhere from 1-2 months depending on how frequently you take it, it will cost $79.99 plus shipping costs.

Is Omega XL Safe?

This is one question that might be persistent when looking at this product because it is different from just a normal fish oil pill. Green-lipped mussels are high in Boron if they are gathered from the right area. According to a study,

“The NZ green lipped mussel extract that is claimed to relieve arthritis was originally gathered from White Island, a volcanic island with vents under the sea. The mussels absorbed boron from the sea in this way and this was the secret to their success. Mussels gathered from other areas do not have the same effect as they lack the boron.” [R]

The key here is the source is extremely important when looking at the effectiveness or lack thereof of Boron which is supposed to relieve inflammation and pain in joints. Without it, there is little success. Boron in large quantities is not safe, so be mindful of that. There is no boron present in this supplement, which makes me question its overall effectiveness.

Pros and Cons of Omega XL

  • Small capsules are easy to swallow
  • Neutral taste (no fishy after-taste)
  • Source of fatty acids clearly displayed
  • Blend of 30 fatty acids
  • Sourced from Green Lipped Mussel
  • Contains Extra Virgin Olive Oil
  • Does not work as effectively as other products
  • High price per dose
  • Lacks a very important ingredient: boron.
  • According to Consumer Lab Review Report on Omega XL: "Omega XL (distributed by Great Healthworks) is described on its website as a "highly concentrated Omega-3 'Super Oil' supplement," for joint pain and inflammation that is "better than standard fish oil." However, when tested this product, it discovered surprisingly little omega-3 fatty acids (EPA and DHA)."


The primary benefits are quite solid. The capsules are quite soft. They are small too. This combination makes them very easy to swallow. We also appreciated that the manufacturer mentioned the source of the fatty acids in these capsules. Most pills just say fish oil. Knowing the source makes this capsule more trustworthy.

OmegaXL® 60 Count – Omega 3 Essential Fatty Acid

omega XL review
  • Blend of 30 fatty acids
  • Sourced from Green Lipped Mussel
  • Contains Extra Virgin Olive Oil
  • Small capsules
Amazon Reviews: 4.7 out of 5 - more than 28,000 global ratings

Amazon Best Sellers: #4 in Omega 3 Nutritional Supplements.



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