10 Best Stem Cell Supplements to Naturally Boost Stem Cell Regeneration (2024 Edition)

Stem cells are special cells in the body that are capable of developing into different cell types such as brain cells, muscle cells, among many others. In addition to that, they also have the ability to repair damaged tissues.  

If you search online for stem cell supplementsyou’re bound to find a long list. Figuring out what to make of all of these supplements can be pretty daunting, as each claims to be the best.

You need to be careful with supplements and health claims and especially stem cell supplements. Why? Generally, the process of creating a new supplement is pretty simple. You go online, find some studies that seem to fit what you’re looking for, create a master file, choose your ingredients, and you’re off. Meaning, no original lab or clinical research is performed.

For example, to create a stem cell supplement, you could focus on the different ways that stem cells get impacted by supplement ingredients, like proliferation. This means that the substance helps stem cells make more of themselves. You then choose from some the ingredients below and you’ve got a new supplement. However, is this really what’s desired? Do you want more stem cells? Is that a good thing or a bad thing? What other impacts do these supplements have on stem cells?

Best Stem Cell Supplements of 2024

There are different ways that stem cells get impacted by supplement ingredients, like proliferation. This means that the substance helps stem cells make more of themselves. 

Here, we’ll start with a few common supplements you might see on the grocery store shelf, to see what the research says about how they impact stem cells. Realize that many of the research studies that can be found on this topic may use a different stem cell type. Hence, we tried to focus mostly on mesenchymal stem cells (MSC). They can both direct tissue repair like a general contractor and also differentiate (turn into) many different cell types like bone, cartilage, muscles, tendon, etc… These cells also have subtypes that come from various tissues like bone marrow, fat, or elsewhere. While similar, these different MSC types are not the same.

So, if you plan to Naturally Boost Stem Cell Regeneration, below are some of the top supplements that you need to consider.

  • Amazon's Choice
  • Ranked No. 1 stem cell supplement by CChit Magazine and Dr Doug Crosby.
  • STEM CELL RENEWAL IS KEY TO LONGEVITY - Stem cells have the ability to create copies of themselves or even transform into other kinds of cells, which helps keep your body’s systems running optimally. But over time, stem cells tend to lose these properties. GeroProtect uses three plant-based nutrients to support a healthy balance of stem cell self-renewal and differentiation for optimal cell health and longevity.
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
  • NUTRIENTS TO ENCOURAGE BALANCED STEM CELL HEALTH - Promotes youthful, healthy stem cell function and encourages balanced stem cell differentiation and self-renewal. It does so with three plant-based nutrients identified by artificial intelligence to promote the cellular pathways that help maintain youthful stem cell behavior, a healthy, functional protein pool, DNA health, AMPK signaling and more.
  • ARTIFICIAL INTELLIGENCE TECHNOLOGY - Traditional clinical trials for stem cell support nutrients can be impractical because of the length of time required. To overcome this, Life Extension partnered with Insilico Medicine, Inc., who used artificial intelligence to identify ingredients that support stem cell health. GeroProtect can help you maintain youthful, healthy stem cell function–so you can live your healthiest life yet.
  • INGREDIENTS MATTER - Sourced using only the finest raw ingredients with the purity and potency your body deserves. This product is certified non-GMO and gluten-free. Manufactured in the USA and a Certificate of Analysis is available for every product we produce.

2. Actif Stem Cell Mega Support with 15 Factors - Non-GMO, 2 Month Supply, Made in USA


  • Ranked No. 2 stem cell supplement by CChit Magazine and Dr Doug Crosby.
  • The most potent stem cell supplement with 15 STEM CELL FACTORS to support stem cell and decrease DNA damage
  • Clinically proven formula to help support stem cell renewal, cognitive function and circulation, anti-aging and regeneration
  • Minimizes oxidative damage in stem cells due to aging and environmental toxins
  • Improves neuron formation and cognitive processed
  • FREE Shipping, Non-GMO, BPA -free, gluten-free, Made in USA, 100% Customer Satisfaction

3. Lifecode Stem Cell 100+: Multi-Pathway Anti-Aging & Regeneration Supplement Supports Stem Cells, Telomeres, More…


  • Acts on Multiple Anti-Aging and Regenerative Pathways to Promote Stem Cells, Telomeres, Longevity Genes, Healthy Inflammation Levels, Vascular Circulation, Neural Function, Autophagy, and More.
  • Free Shipping With Purchase of 3 Bottles or More
  • More Youthful Energy, Stress Resistance, and Vitality; Younger Looking Skin
  • Help for Joint Aches and Pains
  • Doubled Maximum Life Span in an Animal Study

4. Purtier Placenta 7th Edition - 60 Capsules, Made in New Zealand

purtier 7th edition
Purtier 7th Edition


Over 16 years, Riway International has presented one and only supplement in its business which is proudly known as Purtier Placenta. Purtier Placenta has evolved and upgraded the ingredients from 6 to 14 premium ingredients in one capsule. Unique formulation with patented ingredients to achieve complete wellness, repair damaged cells in our body, reverse ageing, prevention of chronic diseases, boost immunity, reduce inflammation and many other benefits. Chart below has statistics of the unprecedented sales over the years globally.


Purtier Deer Placenta health supplement contains fresh deer placenta cell extracts and deer protein that is bio-compatible with human biology. Because of this biocompatibility, deer placenta stem cell extract, along with other natural ingredients, is naturally chosen as the main active component.

Consuming Purtier Deer Placenta health supplement over time will support and maintain healthy cardiovascular functions, cholesterol levels, blood pressure, hormonal balance, joints, youthful vigour, weight loss, immune system, muscle tone, fatigue level and metabolism. 
  • 60 Softgels - Made in New Zealand using High-quality Enteric coating Biosoftgel (aka Liquid Gel) & Nano Emulsification Technology that improve nutrient delivery productivity and allow effective and efficient absorption into the body.
  • NATURAL PRODUCTS - Formulated using 100% finest quality deer placenta extract. Only support government licensed farms, harvested in compliance with the quality standard of placenta food stipulated by New Zealand Government.
  • YOUTH - Antiaging and restorative formulations have often relied upon placenta as a primary ingredient in formulations designed to rejuvenate the body.
  • RECHARGE ENERGY AND VITALITY - Formulated with the combination of Deer Placenta extract with Hyaluronic Acid. Regenerates cells to counter the aging process, protects skin against UV damage.
  • MORE POTENT DEER PLACENTA - Advance synergy formulation, freeze drying and nitrogen filled technology preserve live cells bioactive content for 3-4 years after extraction for longer lasting anti-aging effect.
Where to BuyContact Us

  • The most complete stem cell supplement with 10+ STEM CELL FACTORS
  • Clinically proven formula to help support stem cell renewal, cognitive function and circulation, anti-aging and regeneration
  • Minimizes oxidative damage in stem cells due to aging and environmental toxins
  • Improves neuron formation and cognitive processes
  • FREE Shipping, Non-GMO, BPA -free, gluten-free, Made in USA, 100% Customer Satisfaction

  • CLINICALLY PROVEN IN MULTIPLE HUMAN STUDIES TO INCREASE CIRCULATING STEM CELLS with clinically proven formula shown to double EPCs (endothelial progenitor cells), which are essential in regenerating & replacing damaged blood vessels. Beta glucan, vitamin D3 and ellagic acid further protect stem cells from oxidative stress.
  • PROMOTES ANTI-AGING & INJURY REPAIR by increasing naturally occuring endothelial stem cells up to 100%. Endothelial Stem Cells regenerate and repair the endothelial system (lining of all blood vessels). Endothelial dysfunction is implicated in many chronic diseases. Blood vessel renewal also aids in athletic recovery or rehabilitation.
  • PROTECTS CARDIOVASCULAR HEALTH by encouraging a strong endothelial system, which helps decrease your risk for cardiovascular disease and other chronic diseases. High stem cell count correlates with fewer instances of illness and disease.
  • SOOTHES JOINT ACHES & PAINS by promoting healthy functioning of the circulatory system, boosting systems that impact inflammation and increasing overall immune health. Users reported increased hair and nail growth.
  • 100% NATURAL INGREDIENTS: Contains a patented, heat-treated extract of Lactobacillus Fermentum and the powerful antioxidants astragalus root, goji berry, and green tea. 60 capsules per bottle (one month supply).

7. Regenexx Liquid Advanced Stem Cell Support Formula - Strawberry Banana Flavor

  • Strawberry Banana Flavor Advanced Stem Cell Support Formula is a proprietary blend of vitamins, herbs, and supplements that may help support healthy stem cell function and cartilage production.*
  • 8-IN-1 proprietary blend of vitamins, herbs, and supplements was formulated by scientists and is the only lab-tested formula in its category.
  • Recommended daily dose: 1 ounce one time per day. Refrigerate after opening.
  • Contains a one-month supply at the recommended dose, 32-ounce bottle.
  • 100% MONEY-BACK GUARANTEE: Purchase is backed with our 100% satisfaction, no-hassle guarantee. If you're not happy with the product, we're delighted to provide a refund - no questions asked.Supplement Detailed Information and Ingredients
  • Contains shellfish (shrimp, crab, lobster and/or crayfish) derivatives. Contains corn. Does not contain wheat, gluten, sugar, soy or dairy. Suggested Use: For adults take 1 oz daily or half an ounce twice daily. 1 oz is equal to 2 tablespoons. 1 oz bottle cap included for easy measurement. Wash cap after each use. Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Do not exceed recommended serving.

8. MHD NutriZen Blue Green Algae Complex (AFA), Made in New Zealand

MHD NutriZen is a non-toxic health boosting supplement that improves immunity, heart health, reduces inflammation, reduces weight and mental health. The MHD NutriZen contains 5 key ingredients with Aphanizomenon Flos Aquae (AFA) as the key active ingredient. Known as the world's most complete super food with 83 nutrients, AFA is an edible blue-green algae species that lives in freshwater. 

The 5 key ingredients in MHD NutriZen are AFA (Aphanizomenon Flos Aquae), Green Tea Extract Powder, Olive oil (Olea Europaea), Vitamin D3 (Cholecalciferol) and Bilberry Extract Powder.

Vitamins, minerals and plant nutrients are essential nutrients and antioxidants required by our body to function at optimum level. These broad spectrum of essential nutrients are important to help to fill the nutritional gap that we are missing as we age.

MHD NutriZen Blue Green Algae Complex health supplement is superior to other multivitamin brands, which typically come in powdered capsules and thus have greatly reduced efficacy, due to the technologies they used to retain and optimise the bio activeness of the natural ingredients for up to 4 years.

The Science Behind: The Bluegreen Algae (AFA) Consumption over 48 Hours Increases the Total Number of Peripheral CD34+ Cells in Healthy Patients (Journal of Personalized Medicine 2020)

9. Madre Cell Plus - Stem Cell Supplement Made of Purest AFA for Cells Regeneration and Renewal, Gluten Free Blue Green Algae Enhancer


  • STEM CELLS ENHANCER: Madre Cell Plus stimulates the production of adult stem cells in the bone marrow, releasing them in the bloodstream to reach and regenerate cells where your body needs the most
  • BENEFITS: Helps against most types of ailments such as diabetes, heart problems, rheumatism, varicose veins, spider veins; brain disorders; lack of energy and skin problems
  • CELL RENEWAL: Our stem cells capsules help fighting most heart and brain related conditions by replacing damaged cells with renewed healthy cells promoting a better functioning of the organism
  • MAIN INGREDIENT: Highest and purest form of Aphanizomenon Flos Aquae (AFA), a blue-green algae that supports the release of adult stem cells
  • FEATURES: 100% natural, no side effects, ultra-concentrated AFA formula, gluten free with no sugar, soy or preservatives

10. Stem Cell Supplement (2packs,30 sact,) Reverse Your Biological Clock with Superlife Stc30, No1 Immunity Booster !Clinicaly Proven to Restore and Reactivate Your Stem Cells (1pk is 15sact)


  • BOOSTS IMMUNITY
  • DETOXIFIES THE BODY:* Detoxification which includes but no limited to flushing water from the body. That is why we advise to drink plenty of water while using STC30, at least 2 Liters of water.
  • REJUVENATES THE BODY: It gives you a new lease of life, a new strength . There are so many complementary reports from all our clients worldwide looking younger than they were before and with a sudden boost of strength/energy, vigor & agility.

What To Consider When Choosing The Best Stem Cell Supplements

When buying a new stem cell supplements, you want to make sure you choose the right one. While many factors can affect your decision, some general guidelines can help you choose the perfect stem cell supplements for your needs.

Before becoming interested in stem cell supplements, you may have learned about the stem cell supplements industry. You may also have learned many things to understand, such as the quality of the stem cell supplements, what exactly it is made of, how much it costs, and how it compares with similar products. These factors will all make a difference in what kind of purchase you will make. This article gives tips on how to choose the best stem cell supplements.

Choosing the right stem cell supplements is always difficult because many factors exist. A few general questions should help you narrow down what kind of stem cell supplements you want to buy and how much you should pay.
  • Is the stem cell supplements made of high-quality material?
  • Is it durable and long-lasting?
  • How much does it cost?
  • Is the price reasonable?
  • What kind of warranty does the seller offer?
  • Are there any additional features with this stem cell supplements that might make your purchase worthwhile?
It’s also important to ensure that the stem cell supplements has a solid reputation for quality. You don’t want to buy something that will break down on you within days or weeks of buying it.

When choosing the best stem cell supplements, it is important to consider various factors. The following are some of the most important things you must consider when choosing a product.

Price

It is important to choose an affordable stem cell supplements. You should compare prices before buying to find one that matches your budget. If possible, do not be tempted by low prices because they might not be reliable. You will probably spend more money on repairs and replacements in the future than if you had bought a more reliable product in the first place.

The best way to get a good deal on a stem cell supplements is by shopping around. You can use the internet to find several retailers who sell similar products and then compare prices. This will help you to find a retailer that offers excellent value for money.

Feature

Another important factor is the stem cell supplements features and whether it meets your needs. The more features a model has, the higher the price. If you’re on a budget, look for a simple model with only the basic features. If you have more money to spend and want a model with lots of features, look for one that has more to offer. If you’re looking for a simple model, check out the stem cell supplements reviews. Some models are often praised for having fewer features but being easy to use and providing good performance.

Durability

If you’re using your stem cell supplements frequently or in harsh conditions, then durability becomes even more important than price because failing equipment can cause further damage or injuries if not working properly. Durability depends on several factors, including build quality, materials used in construction, and design features. Choosing a durable model will mean less downtime.

Ideally, you should use a durable product that can withstand heavy use. If possible, go for a product that is made from high-quality materials. This way, even if you use your stem cell supplements frequently, it will remain in good condition for a long time.

Budget

Another important factor that should influence your choice of stem cell supplements is your budget. If you have a tight budget, you should consider buying an affordable model instead of an expensive one that offers little benefit over cheaper models. 

Brand Reputation


The major thing to look at is the brand reputation. You want to find a company that has been in business for a long time and has an excellent track record. If they have been around for years, they are doing something right and have built a good reputation among customers. Check out their website or research online to see what others have said about them.

Customer Support

If you want to know what your future stem cell supplements will be like, look at how the company handles its customers’ problems. If there are many complaints on forums and social networks about poor customer service, there are problems with this particular brand or model. It would be better to choose another brand if you care about your comfort and convenience.

Customer Reviews

Another important thing that should not be ignored is customer reviews. People who have already used stem cell supplements can share their impressions with other users, so it is worth reading them before making a purchase decision. In addition, if you have any questions regarding the product’s features or specifications, this information can also be found in the reviews.

Specific Supplements and Diet

Here we’ll start with a few common supplements you might see on the grocery store shelf, to see what the research says about how they impact stem cells. Realize that many of the research studies that can be found on this topic may use a different stem cell type. Hence, we tried to focus mostly on mesenchymal stem cells.

So, if you plan to naturally boost stem cell regeneration, below are some of the top science backed supplements that you need to consider.

1. Glucosamine and Chondroitin

Glucosamine has been associated with reduced mortality in humans (R,R), and can extend lifespan in animals (R,R).

Glucosamine can for example help mesenchymal stem cells to generate cartilage cells (R). Glucosamine can also improve stem cell proliferation in the gut (R,R).
 
These two supplements are commonly used in arthritis treatments and are often derived from shellfish. Hence it makes sense that glucosamine can promote MSCs (Mesenchymal Stem Cells) to become cartilage and inhibit the breakdown of cartilage. Chondroitin can also enhance the ability of MSCs to turn into cartilage (R).
 
Chondroitin also has real measurable effects on knee cartilage in actual patients. In one study, it reduced cartilage volume loss on MRI after 6 months (R). Glucosamine also seemed to help cartilage quality when measured on a specialized MRI (R). In another study, glucosamine reduced cartilage breakdown products (R). Finally, when compared to prescription Celebrex, the combination of glucosamine and chondroitin were better at improving function and reducing cartilage breakdown in the knee (R).

2. Curcumin (Turmeric)

The most commonly promoted anti-inflammatory supplements right now are curcumin and turmeric. Turmeric and curcumin are derived from the turmeric root with turmeric being the spice you know from Indian cooking, and curcumin one of the chemical compounds known as curcuminoids, which are believed to be biologically active. In addition, in order for curcumin to be absorbed in the gut, a black pepper extract is commonly required.

In one study that used adipose MSCs to treat heart attacks, curcumin improved the viability of the cells, reduced scarring in the heart muscle being repaired, and promoted new blood vessel formation (R). In another involving bone marrow MSCs, curcumin improved bone formation (R).

The curcuminoids also impact arthritis through anti-inflammatory pathways and reducing inflammatory cytokines. All of these effects have translated into real measurable impacts on patients with knee arthritis (R). In other studies, Curcumin has been shown to be as effective as common NSAID anti-inflammatories such as Diclofenac (R).

By itself, curcumin is poorly absorbed. Among the methods devised to address the issue, the most common (and most often tested) is to pair curcumin with piperine (a black pepper extract).

To supplement curcumin with piperine, take 500 mg of the former with 5-6.7 mg of the latter, thrice a day (i.e., 1,500 mg of curcumin and 15-20 mg of piperine per day) (R).

3. Resveratrol and Pterostilbene

Resveratrol (RSVL) is a natural type of polyphenolic phytoestrogen and is mainly found in red grapes, blueberries, peanuts, and other plants. The effect of resveratrol on stem cell is well documented (R). 

It also helps MSC (mesenchymal stem cell) differentiation into osteogenic (bone related) cells and suppresses differentiation into the fat related tissue lineage [R]. 

The combination therapy of MSCs (mesenchymal stem cell) transplantation and resveratrol has also played a great therapeutic effect in animal models of diabetic complications (RRR).

According to Examine.com:
  • The lower end of supplementation tends to be for cardiovascular health, insulin sensitivity, and longevity for somebody who is otherwise unhealthy is 5-10mg daily. For persons who are otherwise healthy, dosages between the range of 150-445mg have been used (with no clear indication for what is the optimal dose).
  • Supplementing for cerebral blood flow requires a dose in the 250-500mg range whereas supplementation for aromatase inhibition requires 500mg as well.
  • Supplementation of resveratrol refers to trans-resveratrol exclusively.

4. Quercetin and Fisetin

This can be found in many fruits, vegetables, grains, and leaves. Kale and red onions are examples of foods that contains an appreciable amount of quercetin among many others. It comes with a bitter flavor and is commonly used as an ingredient in foods, beverages, and dietary supplements.

Here are the benefits of quercetin: 
  • Antioxidant
  • It supports mitochondria
  • It can prevent the death of cells
  • It can protect your body by reducing your stress levels
  • It can serve as a natural antihistamine and can get rid of allergy symptoms
  • It is a safe alternative to painkillers since it can treat arthritis and joint pain
  • Research suggests that it can support stem cell growth and differentiation (R)
The recommended dosage for quercetin: 
  • Currently, there are no ideal amounts set by the scientific community. You can ask your doctor regarding this one to find out how much is needed based on your health's current status.
  • Majority of supplements require 500mg and it has to be taken twice daily. But with quercetin, you can already experience the benefits even if you take something lesser than that considering that it's known to be diet rich.
According to Examine.com:
  • Dosages of quercetin used are in the range of 12.5 to 25mg per kg body weight, which translates to a range of 1,136-2,272mg daily consumption of quercetin when in isolation.
  • It is suggested to supplement with other bioflavonoids such as resveratrolgenistein, or green tea catechins to increase the potency synergistically and theoretically get the benefits at a reduced level of intake.
  • When looking for quercetin, the form of dihydrate has the apparent best bioavailability followed by glycosides, aglycone, and finally rutinoside.
Fisetin is a molecular cousin to quercetin. Fisetin is a naturally occurring substance found in fruits and vegetables, such as strawberries, apples, grapes, onions, and cucumbers. 

Substances like fisetin reduce inflammation (R,R) and help the body to clear senescent cells, leading to an increased lifespan (R).

Fisetin has shown to reduce aging-related increase in inflammation and lower toxic substances senescent cells secrete which damage stem cells (R).  

5. NMN (nicotinamide mononucleotide)

NMN is a substance that increases NAD levels in our cells. NAD is a pivotal molecule to protect and repair DNA and the epigenome, including in stem cells.

NMN can improve and protect stem cells such as mesenchymal stem cells that form bone and fat tissue (R,R).

Researchers from the East China University of Science and Technology in China show that nicotinamide mononucleotide (NMN) — an NAD+ precursor known to elevate NAD+ levels — helps to maintain the functional longevity of stem cells in a dish, which can lead to improved effectiveness of stem cell therapies. As published in Antioxidants (2023), Zheng and colleagues report that NMN enhances stem cell migration, diminishes stem cell ROS, and prevents stem cell senescence.

6. Vitamin C and AKG (Alpha KetoGlutarate)

Vitamin C can also improve stem cell health (R,R).

But ideally, vitamin C has help from alpha-ketoglutarate, given these two substances are substrates for important epigenetic enzymes, such as the TET enzymes (R).

7. Glycine (Amino Acid)

Glycine is a naturally-occuring substance in our body; in fact, it’s an amino acid. However, during aging, levels of glycine decline.

Glycine has shown to improve stem cell health (R,R). It can do this by protecting proteins in cells, or by inducing autophagy, which is the digestion of cellular waste.

8. Molecular Hydrogen

Molecular hydrogen is the smallest anti-oxidant. The ability of molecular hydrogen (H2) to protect the DNA and the mitochondria from oxidative damage may have beneficial effects on chronic diseases and cancer. But perhaps it could help slow down or reverse the aging process itself. A couple of cellular studies give us some interesting clues [R, R].

It was already discovered that hydrogen can prolong the life of stem cells by reducing oxidative stress
(Biochem Biophys Res Commun. 2010).

A hydrogen-rich environment reduced both oxidative stress and aging in cells. Some scientists think
that drinking hydrogen water could increase longevity in humans (Circ J. 2016).

9. Olive oil and Mediterranean Diet

PubMed has indexed 30 research studies on olive oil and stem cell.

A Mediterranean diet rich in virgin olive oil is effective in boosting stem cells. A 4-week control study published in The American Journal of Clinical Nutrition (2011) showed that compared to those on a diet high in saturated fat or a diet low in fat but high in carbohydrates, those on a Mediterranean diet rich in virgin olive oil showed a significant doubling in their endothelial progenitor cell count in the blood.

Epoch Times Photo


10. Dark chocolate

Dark chocolate contains flavanols that have biological properties. Researchers at the University of California recruited patients with coronary artery disease in a 30-day controlled trial. One group drank hot chocolate low in flavanols (only nine mg per serving) twice a day, and the other group drank hot chocolate high in flavanols (containing 375 mg per serving) twice a day. The results were surprising: the group with high-level flavanol had twice as many stem cells in their blood as that with low-level flavanol, and the former’s blood flow improved twice as much as the latter.

11. L-Carnosine (Amino Acid)

L-Carnosine is a “performance enhancer” amino acid shown to enhance muscular endurance. In fact, many who take this potent ingredient report being able to dramatically increase strength performance at the gym, as well as:
  • Burn more fat [R]
  • Show to increase adult stem cell proliferation by 25% in vitro [R]
  • Increase lean muscle [R]
  • Improve cardiovascular performance [study]
12. Taurine

Stem cells hold the key to tissue repair and regeneration. But as the body ages, its numbers and activity decline.

Studies have shown that taurine can help stimulate stem cell production (Nutr Neurosci 2017), particularly neural stem cells, which can boost brain function, in addition to regenerating various tissues throughout the body.

13. Blue Green Algae

The Science Behind: Bluegreen Algae (AFA) Consumption over 48 Hours Increases the Total Number of Peripheral CD34+ Cells in Healthy Patients (Journal of Personalized Medicine 2020).

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