Fenbendazole for Cancer: A 2022 Review

What Is Fenbendazole?

According to Wikipedia, Fenbendazole (also called Fenben) is a broad spectrum anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits, most reptiles, freshwater shrimp tanks as planaria and hydra treatments, as well as seals.

Common brand names include Pancur, Panacur C and Safe-Guard.

However, it is also being used by humans in a cancer treatment method known as the Joe Tippens Protocol.

Is fenbendazole a cancer cure scam? 

One study suggests that fenbendazole has “been safely utilized as an anti-parasitic for various different animal species and could be repurposed for treating human malignancies.” Other benzimidazoles, including albendazole, parbendazole, mebendazole and flubendazole have already been shown to have promising results in humans

Another study states that the “repurposing of veterinary drugs showing promising results for human use can result in considerable time and cost reduction required to develop new drugs.”

Is Joe Tippens, My Cancer Story Rocks, and Fenbendazole Fame Still Alive?

One of the contributors from CancerDefeated.com met Joe in person and interviewed him in April 2022. Here’s what she discovered…

Joe’s scan was completely clear in early 2017. His scan in Feb. 2022 still shows no evidence of disease.

Since cancer is notorious for recurrences, Joe continues to follow his regimen for prevention… and plans to for the rest of his life. However, he recently revamped the rest of his entire cancer treatment protocol.

Joe has scaled back to three days a week on the FenBen, now that he’s been cancer-free for five years. He recommends staying on the seven-day fenbendazole protocol till you’re cancer-free for at least three years.

Based on his extensive research, he’s added things to his protocol. including Frankincense and berberine. All products are in a much more bioavailable form, too. He notes that getting absorption of nutrients into the bloodstream is a bigger problem than most people realize. His new protocol helps address this problem.

Joe spent much of 2021 collaborating with scientists and M.D.’s in the pharmaceutical and nutraceutical space, to develop processes that dramatically improve nutrient delivery into the bloodstream at previously unheard-of levels.

Here’s the three-pronged approach he uses in 2022 (R):

1: Support healthy cell division. Joe consumes cryogenically extracted CEM™ Hemp. Getting the terpenes and cannabinoids from full-spectrum hemp is critical to gaining its best benefits. The product is now cryo-extracted to preserve these substances. It also includes Frankincense and a Nano MCT oil.

2: Support healthy cell life cycles and clearance of dead cells with curcumin. Curcumin was always part of Joe’s protocol. He previously used the most bioavailable curcumin product he could find. He cringes when he relates how much he was depending on a nutrient that’s so extremely challenging to absorb, while fighting a deadly disease. The new product he uses is light years ahead in terms of absorption – at least six times better – thanks to new technology.

3. Support optimal cellular glucose metabolism with berberine. Berberine is known for its effects on insulin resistance and the normalization of blood glucose levels. Since cancer cells use glucose to grow and spread, berberine helps starve those cancer cells. (Incidentally, he also recommends you strip sugar from your diet, but admits he’s poor at practicing what he preaches.)

All three of these nutritional products are available through a company called Ultra Botanica in their Onco-Adjunct line. Joe made it very clear that he makes no money from recommending any of these products, nor does he own any stock or other interest in the company. He simply thinks their products are the best now available for his protocol and he’s been recommending them since late in 2021.

Q&A Session with Joe Tippens (Jan 2022)



Is Fenbendazole Safe For Humans With Cancer?

While little research has been done on the effects of fenbendazole and human consumption, studies have shown that the medication is typically tolerated well by humans, and thus far, has not reported any major side effects. While we can’t state that fenbendazole is safe for humans, the research appears promising.

According to a 2018 study, Fenbendazole (methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl) carbamate) is a broad-spectrum benzimidazole anthelminthic approved for use in numerous animal species. Repurposing of veterinary drugs showing promising results for human use can result in considerable time and cost reduction required to develop new drugs. Fenbendazole is known to have a high safety margin and most species tolerate it very well. It has very low degree of toxicity and high degree of safety in experimental animals.

Another study also discussed the potential side effects of using fenbendazole in humans. “Based on limited human data it appears that doses up to 500 mg per person did not result in adverse effects,” the study states. “Moreover, single doses up to 2,000 mg per person were reported to cause no adverse effects.”

Fenbendazole For Cancer In Humans

This study revealed when testing cancer cell lines against the off-label drug, “the group supplemented with both vitamins and fenbendazole exhibited significant inhibition of tumor growth.” 

Another study suggested, “it caused mitochondrial translocation of p53 and effectively inhibited glucose uptake, expression of GLUT transporters as well as hexokinase (HK II) – a key glycolytic enzyme that most cancer cells thrive on.” 

While I’ve discovered positive studies, there are others that show no benefits of Fenbendazole, so we must take a balanced approach.

Joe Tippens Protocol Dosages


- Fenbendazole: 222 mg per day seven days a week with food.
- Curcumin: 600 mg (2 pills per day) of bio-available curcumin 7 days a week.
- CBD oil: 25 mg sublingually (under the tongue) seven days a week.
- Vitamin E (optional): 400-800mg per day, seven days a week.


Best Fenbendazole For Humans

Merck and Safeguard are well established companies whose products have been safety tested in animals and used by veterinarians for many years.

1. Safe-Guard Dewormer for Cancer


Buy on Amazon

How To Use Fenbendazole for Cancer

It can be taken as a single dose in the morning, with or without food. 

It may be best to place the powdered substance directly in your mouth and chase it down with a flavored drink such as cranberry juice as it does not dissolve well in any liquids. You could also try to mix it into a smoothie, greens drink, or something else. 

Fenbendazole for Cancer Dosage

One box of three packets will last a week on the beginning dose since you take one packet per day for three straight days and then take FOUR DAYS OFF. Example: Take the Fenbendazole only on Monday, Tuesday, and Wednesday each week. 

Those with later-stage cancers may choose to take 2-3 packets per day and take no days off!

Do not follow the weight-dependent dosing (for dogs) that is given on the back of the packaging!
 

2. Panacur-C for Cancer

Buy on Amazon

How To Use Panacur C for Cancer

It can be taken as a single dose in the morning, with or without food. 

It may be best to place the powdered substance directly in your mouth and chase it down with a flavored drink such as cranberry juice as it does not dissolve well in any liquids. You could also try to mix it into a smoothie, greens drink, or something else. 

Panacur C for Cancer Dosage

One box of three packets will last a week on the beginning dose since you take one packet per day for three straight days and then take FOUR DAYS OFF. Example: Take the Fenbendazole only on Monday, Tuesday, and Wednesday each week. 

Those with later-stage cancers may choose to take 2-3 packets per day and take no days off!

Do not follow the weight-dependent dosing (for dogs) that is given on the back of the packaging! 


While little research has been done on the effects of fenbendazole and human consumption, studies have shown that the medication is typically tolerated well by humans, and thus far, has not reported any major side effects. While we can’t state that fenbendazole is safe for humans, the research appears promising.

Fenbendazole is a benzimidazole used to treat cancer as part of the Joe Tippens Protocol
According to a 2018 study, Fenbendazole (methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl) carbamate) is a broad-spectrum benzimidazole anthelminthic approved for use in numerous animal species. Repurposing of veterinary drugs showing promising results for human use can result in considerable time and cost reduction required to develop new drugs. Fenbendazole is known to have a high safety margin and most species tolerate it very well. It has very low degree of toxicity and high degree of safety in experimental animals.

Another study also discussed the potential side effects of using fenbendazole in humans. “Based on limited human data it appears that doses up to 500 mg per person did not result in adverse effects,” the study states. “Moreover, single doses up to 2,000 mg per person were reported to cause no adverse effects.”

FAQs

Can fenbendazole be taken in tablet, liquid or powder?

Fenbendazole is available in tablets (Happy Healing Store), liquid (Safeguard) and powder (Panacur). There may be other formulations available, but those are the primary products that patients are using.

Is it safe for humans to take fenbendazole?

Since fenbendazole is a veterinary medicine, and is not licensed for human use and there is no specific human safety data available. The similar human forms of this class of medications, mebendazole and albendazole, have been used for parasitic infections for many years and have a good safety record. Fenbendazole has been reported to have a very low degree of toxicity and a high degree of safety in animal experiments.

Is fenbendazole toxic for the liver?

Although fenbendazole is generally well tolerated, there have been reports of elevated liver enzymes from the use of fenbendazole, as well as the human medications mebendazole and albendazole. 

I’ve found a Fenbendazole brand which is not made by Merck, is it ok?

There are a variety of opinions on which product is best, but no research exists that compares the effectiveness of various formulations in humans. Merck and Safeguard are well established companies whose products have been safety tested in animals and used by veterinarians for many years. 

Would the fenbendazole protocol work with conventional treatment? - chemotherapy?

Yes, fenbendazole has the potential to synergize with conventional treatments, and possibly enhance treatment response. Some aspects of the protocol, such as vitamin E and curcumin, may interfere with chemotherapy and radiation due to their anti-oxidant properties. 

Some people take it 3 day on 4 off, some 1 gram a day, some 2 or even 4 grams a day. What is the correct dosage?

Joe Tippens, who popularized the use of Fenbendazole for cancer, recommends 222 mg for three consecutive days, then four days off. There are many people who take larger doses, more frequently. Since Fenbendazole is not licensed for the treatment of cancer in humans, there is no correct dose that is supported by research, pharmacists or physicians. The dose you choose to take should be assessed based on your other medications and treatments, your type of cancer, prognosis, organ function and lab values.

How long do I need to be on this protocol?

This will be up to you based on your treatment response to the protocol. It is reported that Joe Tippens continues to use the protocol for prevention.

How do I know when it is time to dose up?

This is an individual decision based on treatment response, tolerance, other treatments/medications and lab values. 

Fenbendazole Publications and References

1) Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways.
https://www.nature.com/articles/s41598-018-30158-6

2) Unexpected Antitumorigenic Effect of Fenbendazole when Combined with Supplementary Vitamins.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687140/

3) Fenbendazole as a Potential Anticancer Drug.
http://ar.iiarjournals.org/content/33/2/355.full

4) The Anthelmintic Drug Mebendazole Induces Mitotic Arrest and Apoptosis by Depolymerizing Tubulin in Non-Small Cell Lung Cancer.
https://mct.aacrjournals.org/content/1/13/1201.long

5) Pilot study of albendazole in patients with advanced malignancy. Effect on serum tumor markers/high incidence of neutropenia.
https://www.ncbi.nlm.nih.gov/pubmed/11474247

6) Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis.
https://www.ncbi.nlm.nih.gov/pubmed/15565325

7) Benzimidazole as Novel Therapy for Hormone-Refractory Metastatic Prostate Cancer.
https://apps.dtic.mil/dtic/tr/fulltext/u2/a545657.pdf

8) Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.
https://www.ncbi.nlm.nih.gov/pubmed/18667591

9) Phase I clinical trial to determine maximum tolerated dose of oral albendazole in patients with advanced cancer.
https://link.springer.com/article/10.1007%2Fs00280-009-1157-8

10) Repurposing Drugs in Oncology (ReDO) — mebendazole as an anti-cancer agent.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096024/

11) Anthelmintic Flubendazole and Its Potential Use in Anticancer Therapy.
https://pdfs.semanticscholar.org/2b47/0bf133be75b36c09ebc8b17e70cea85fd9af.pdf

12) Chronic myelogenous leukemia in a great horned owl (Bubo virginianus)
https://www.ncbi.nlm.nih.gov/pubmed/19530405


Find Integrative Oncologists in USA

This is a 3 part directory (categorized by state in USA). Check out part 1,2 and part 3:

Notes and Disclaimers: 
  • Please do not consider this guide as personal medical advice, but as a recommendation for use by professional providers. Consult with your doctor and discuss with her/him. 
  • Our aim here isn't to replace your doctors' advice. It is intended as a sharing of knowledge and information. Do take note that most treatments are not 100% protective or curative against cancer. It's a continuous struggle between the immune system and the cancer cells. Cancer treatments are meant to assist the immune system in this battle.
  • Cancer treatment should be part of a multi-modal approach in order to provide the best possible outcome. Diet and lifestyle changes are meant to run alongside conventional treatment. They are complementary, not alternative. That said, there is no miracle treatment that can cure all cancers.


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