10 Best Topical Pain Relief Products 2022

Chronic joint pain affects almost one-quarter of people worldwide. Common joints affected include the knees, hands, elbows, shoulders, back and elsewhere. In most cases, this is caused by the most common type of arthritis, osteoarthritis. 

Topical painkillers are products that you apply onto your skin to provide relief for joint and muscle aches.

What Is The Main Cause of Joint Pain?

The most common causes of chronic pain in joints are: Osteoarthritis, a common type of arthritis, happens over time when the cartilage, the protective cushion in between the bones, wears away. The joints become painful and stiff. Osteoarthritis develops slowly and usually occurs during middle age.

How Can I Stop Joint Pain?

- Stay at a healthy weight. Extra pounds put pressure on weight-bearing joints like hips and knees. Each pound you gain adds nearly four pounds of stress on your knees and puts six times the pressure on your hips.

- Control your blood sugar. High blood sugar can stiffen the tissue that supports your joints and make them more sensitive to stress.

- Exercise. Just 30 minutes of exercise five times a week helps joints stay limber and strengthens the muscles that support your knees and hips. Focus on low-impact exercises like walking, cycling or swimming.

- Stretch. Gentle stretching can improve your range of motion and keep your joints limber. Try to work in simple stretches into every day.

- Avoid injury. An injured joint is more likely to develop arthritis than one that was never injured. Wear protective gear when playing sports and always lift with your knees and hips, not your back. 

- Quit smoking. Smoking puts stress on tissues that protect your joints and can lead to arthritis pain. Learn how Blue Cross can help you quit.

- Eat fish twice a week. Eat fish high in Omega-3s, like salmon, trout and mackerel. Omega-3s have many health benefits and may reduce inflammation.

- Get routine preventive care. Your doctor may be able to suggest lifestyle changes that can help reduce your risk or slow the progress of arthritis.

Best Topical Pain Relief Products 2022

1. Penetrex Joint and Muscle Therapy Cream - Best Muscle and Joint Relief Cream

- Penetrex Pain Relief Cream
- Intensive Concentrate for Relief & Recovery 
- Whole-Body Formula with Arnica, Vitamin B6 & MSM (DMSO2) 
- Penetrex is recommended for use on its own & is safe to use in conjunction with complementary therapies such as Heating Pads, Ice Packs, Back Massagers, Knee Braces and Supplements.
- Relief & Recovery for Joints & Muscles on your Back, Neck, Knee, Hand, Foot, and more. 
- Contains unique ingredients including Arnica, Glucosamine, MSM (DMSO2), Choline, Boswellia Serrata (Frankincense) & Vitamin B6 deep into the tissue to soothe affected areas.
- Vanishing scent / non-greasy / non-sticky / non-staining / paraben-free 
- Vegan and Cruelty-free (never tested on animals).

4.3 out of 5 - 70,458 global ratings

 If I wake up with a sore back or neck, I rub this in and it instantly diminishes the pain at least 75 percent. I rubbed it into my hands and wrists and it helped my carpel tunnel at least 40- 50 percent. 

Buy on Amazon

2. Topricin Pain Relief Cream 8oz - Best Pain Relief Cream for Joint Pain

Topricin is moisturizing, non-irritating, odorless and non-staining. It supports the body's natural processes that work to Heal the Cells Causing the Pain. Topricin has 22-years of history in the medical community and is used by hundreds of thousands all over the world.

Topricin contains 11-natural biomedicines delivering reliable pain relief, improving quality-of-life, and providing a strong adjunct to professional care with no side effects and won’t interfere with other medications

The safest alternative for people who cannot tolerate prescription and non-prescription OTC oral pain medication. It stimulates and supports your body's desire to ""Heal the Cells that are Causing the Pain"". Topricin is safe effective and ideal treatment for the entire family and for all skin types.

- Topricin Pain Relief Cream
- Fast acting pain relieving cream

• Headaches, Joint, Muscle, Nerve Pain
• Post-Surgical Pain
• Carpal Tunnel Syndrome (CTS)
• Injury of Hand, Wrist and Fingers
• Joint Pain: (neck, shoulders, back, wrist, hand, knee and fingers)
• Neck & Shoulder Pain/Bursitis
• Lower Back Pain / Sciatica
• Sports / Trauma Injuries / Impact Injuries
• Dislocations and any other trauma injuries of the joints and muscles
• Ankle Sprain & Heel Spurs
• Muscle Spasm/Night Leg Cramps
• Tennis/Golfers Elbow/Tendonitis
• Scar Tissue Management

• 11-natural Homeopathic Biomedicines
• Safe, Effective And Gentle
• Will Not Interfere With Any Medication
• Effective For Pain Associated With A Wide Range Of Ailments
• Ideal For The Entire Family: Elderly, Children
• Guaranteed To Work Or Your Money Back
• Made In The USA

- Generously apply 3 to 4 times daily or more if needed, 3 inches on and around affected area.
- Massage in until absorbed.
- Use before and after sports workouts and competitions.
- Apply immediately for acute trauma.
- Seek immediate medical attention if pain or swelling is severe.
- Reapply before bedtime and in the morning for Best Results.
- For external use only Do not apply in eyes. Use only as directed.

4.4 out of 5 - 4,770 global ratings
I have neuropathy in my feet/legs and find that using this cream at night before bedtime really helps things calm down so I can sleep. I recommend this to others who are looking for a cream to use for similar reasons.

3. Voltaren Arthritis Pain Gel - Diclofenac Sodium Topical Gel for Knee Pain

The Voltaren emulgel formula, which combines a cream and a gel, penetrates deep through the skin to deliver powerful arthritis pain relief. When applied to the skin it creates a cooling and moisturizing effect.

Voltaren provides targeted pain relief in the areas you need it most. All you have to do is rub Voltaren directly to the site of pain. Voltaren Arthritis Pain Gel can be applied to your hands, wrists, elbows, feet, ankles, and knees.

Voltaren relieves arthritis pain, improves mobility and reduces stiffness to provide prescription strength arthritis joint pain relief.

- Voltaren Topical for Back Pain
- Topical Arthritis Pain Relief
- Contains One 3.5 oz/100 g tube and one 0.71 oz/20 g sample tube 
- Non-greasy Voltaren Emulgel combines the properties of an arthritis pain relief cream and a gel to target pain
- Diclofenac sodium topical gel penetrates deep to attack arthritis pain directly at the site, treating pain rather than just masking it
- Apply on up to two joints at the same time for hand pain, wrist pain, elbow pain, ankle pain, foot pain or knee pain relief

4.4 out of 5 - 7,188 global ratings

So I did not expect much... I put some on my elbow which had moderate pain. Then I applied to my right foot at the ball of the big toe where it attaches to the foot. I have had trouble walking on it for about a year. This hurt a lot. To my amazement I had about a 90 % percent reduction in pain in about 30 min! 600 mg of Ibuprofen would barley knock the edge off. I will buy again.

4. Lidocaine 4% Topical Analgesic Cream, 3oz - Muscle Pain Relief Cream

lidocaine pain relief cream

- Lidocaine Topical for Back Pain

This pain reliever cream works to desensitize aggravated nerves with the numbing relief of maximum strength 4% lidocaine HCl as an active ingredient. It is formulated with a light tropical jasmine scent that is both soothing and pleasant and a non-greasy formula that doesn't leave any residue behind

Benefits of Bengay
Localized treatment - allows you to concentrate treatment only on affected area
Speed of effect - ingredients do not have to travel through the bloodstream and are absorbed directly into affected area
Lightly scented lidocaine cream has a soothing and pleasant scent

- Works to desensitize aggravated nerves with effective, numbing relief. 
- Formulated with 4% lidocaine HCI as an active ingredient
- The topical analgesic cream also helps relieve pain. 
- 3-ounces of Bengay Pain Relieving Lidocaine Cream for maximum strength pain relief in a fresh tropical jasmine scent
- Great for back, neck, shoulder, knee, elbow, hand & wrist pain, as well as backaches, joint pain and arthritis
- For use, apply the topical lidocaine cream to the affected area no more than 3-4 times a day for effective, numbing relief

4.5 out of 5 - 8,791 global ratings

Amazing scent, smells like a jasmine perfume, and super effective!!!!!!! I have ankylosing spondylitis , psoriatic arthritis, and fibromyalgia! Super helpful for the muscle / joint pain, and for my nerve pain it reduces the swelling.

5. MaxRelief Arnica Montana Pain Cream - Best Topical Pain Relief for Arthritis 

- Anti Inflammatory Cream for Arthritis
- For Sufferers of Knee, Joint & Outback Muscle Pain. Reduce Arthritis & Joint Inflammation. 
- Plantar Fasciitis & Fibromyalgia Relief + Emu Oil 3.5 oz

Apply MaxRelief anywhere you experience Pain, Discomfort, Tingling, or Numbness including your Back, Neck, Knee, Hand, Wrist or Foot. Excellent for Sciatic pain. MaxRelief works on its own or with complementary therapies such as Heating Pads, Ice Packs, Arthritis Gloves, Back Pain Massagers, Tennis Elbow Straps, Carpal Tunnel Braces, Fibromyalgia Supplements, Neuropathy Socks, Sciatica Cushions, Tendonitis Supports, Bursitis Braces, etc.

Sufferers all over the world have now discovered our unique formulation. Arnica montana (a mountain flower) has been used for centuries as a natural pain reliever, and today, it’s one of the most popular natural medicines in the world. MaxRelief is 23% Arnica – 3 times that of other leading products. Maximum Strength, compared to Arnica Gel at 7%

We are the ONLY pain relief cream to include the tremendous pain relief benefits of Arnica, Eucalyptus, & Emu Oil in one incredible product. Support for Wrist and Lower Back pain. Arnica is trusted by professional athletes to soothe sore muscles, by prominent cosmetic surgeons to relieve post-procedure pain, and by savvy moms to treat playground bumps and bruises.

Reduces arthritis pain, tingling and joint inflammation while increasing capillary circulation. Just rub it in.

Arnica for Inflammation. Emu Oil for Cell Regeneration, Rosemary for Improved Blood Flow. 

- Vanishing Scent 
- Made in the USA 
- Non-Greasy / Non-Staining 
- Paraben-Free 

4.3 out of 5 - 2,522 global ratings

MaxRelief Arnica is absolutely amazing! Not only does it provide extremely fast pain relief in a matter of minutes but it doesn't just provide a 'bandaid' of temporary relief and instead the anti-inflammatory aspect of the compound helps to decrease inflammation to the area of pain and promote healing.

6. Salonpas Pain Relieving Patch - Best Topical Pain Relief Patch

- Salonpas Pain Relief Patch
- For Back, Neck, Shoulder, Knee Pain and Muscle Soreness 
- 8 Hour Pain Relief 
- 60 Count

Pain relieving patch
These comfortable, convenient and effective topical pain patches have 3 powerful pain fighters that work at the site of pain; Analgesics include camphor, menthol and methyl salicylate

Versatile comfort
With rounded corners and flexible fabric, application is easy and the patches bend with your movements

Targeted relief
Provides temporary relief of pain associated with sore back, neck, wrist, ankle, hip, shoulder, knee and elbow; Help alleviate muscle soreness, backache, joint pain and sprains

For penetrating, mess-free and targeted relief, apply spray or patch to manage pain in specific areas; Salonpas pain relieving patches and sprays offer pain relief for up to 8 hours

Soothe your pain
With pain relief patches, sprays, creams, gels and liquids, Salonpas is here to help you get through your day with discreet, easy-to-use, topical pain relief for temporary relief of aches and pains

- The patches stay where you need them and are easy to remove.
- Do not use with a heating pad

4.6 out of 5 - 21,962 global ratings

These are amazing. I have struggled with trapezius tightness for years. Massage and relaxing help but who has time to be a lady of leisure? The NSAID in this is the bomb. I am a nurse and recommend it to my patients. For those who must avoid NSAIDS, I have verified with the clinical pharmacist at work that microscopic amounts of it are absorbed systemically, allowing for full freedom to use topically. Totally cures the pain. I wear it to bed and wake up a new person. Mild mediciny smell but it’s more like eucalyptus than anything else. Totally tolerable.

7. Kailo Pain Relief Patch - Knee Pain Relief Patches

Kailo’s patented technology uses nanocapacitors to “turn off” your pain like a light switch – that may provide natural relief, anywhere on your body, in seconds.

Kailo has hundreds of applications. Patients say it quickly turns off pain in the head, neck, shoulder, back, knee, hand, foot, and more!

Correctly place Kailo wherever you feel pain and watch it disappear almost immediately.

Unlike drugs, the Kailo patch is non-transdermal (which means no chemicals or medicine enters your body) and is made with 100% natural occurring elements.

Worn over and over, day after day, without losing functionality. Just replace the adhesive after 3-7 days of continued use and you’re good to go. No other pain relief product offers so much value for a one-time purchase.

The strength of our body’s electrical field allows Kailo to target the pain when its placed on your skin.

Extremely durable and designed to handle any physical activity or weather condition. Wear Kailo in the shower, in the pool, during a workout, running errands & more.

Kailo Pain Relief How To Use
Step 1) Move Kailo over the part of your body where you want to target pain. Hold the Kailo patch for a few seconds, slowly moving it around the targeted area to find the maximum pain relief. You may be surprised to find that placing the patch on your elbow relieves pain further down or up your arm. That’s how pain signals work. Adjust Kailo as needed until you find the spot for optimum pain relief.

Step 2) Unpeel the adhesive backing, then attach it to the Kailo patch. Your Kailo starter kit comes with a pack of adhesive patches. You unpeel the backing from the adhesive patch, then place it on the back of the Kailo patch device. Press the adhesive firmly against Kailo. Smooth the adhesive to ensure you can reuse the patch over and over again.

Step 3) Unpeel the clear adhesive backing, then apply the patch to your skin or clothing. Once you’re ready to use Kailo to target pain, just peel the other half of the adhesive backing and apply it to your skin or clothing. Leave the patch on for several minutes or several hours. Most people seem to experience maximum pain relief within 5 to 10 minutes of applying the patch, although your experience may vary.

That’s it! You can reuse each adhesive patch multiple times. Just remove the patch from your skin, wash it with water, then let it dry to restore the stickiness.

Kailo Pain Relief Reviews
I received your product yesterday and immediately started using it. It took me about 3 minutes before I found a good spot on my upper back. The pain went away within seconds. I have been suffering from daily muscle spasms and tightening that was so painful. This would happen daily when I walked for more than a couple of minutes and when I would lie down to sleep. This has gone on for over 4 years . MRI’s , Xrays, chiropractor, massage therapy, orthopedist. I have tried everything and still ..pain. I know that your product isn’t fixing the issue, but it has (so far) given me amazing relief from the daily pain that I’ve been feeling. I have told several people about this product and I have no doubt that they will be ordering from you. Thank you so much for developing this amazing technology and delivering it at a reasonable price!!

8. Coralite Muscle and Joint Pain Relief Patch

- Topical analgesic
- Perfect for Small and Hard-to-cover areas
- Hours of relief to aching muscles and minor pains due to arthritis, strains, bruises, and sprains
- Double-sided packaging
- Adhesive patch
- Coralite Pain Relief Patch
- Extra Strength Joint & Muscle Pain Relief Patches for Back Pain, Muscle Soreness and Joint Pain
- 2 Patches Per Pack (24 Pack)

Coralite backache patches helps to relieve minor aches and pains by targeting the affected area and delivering concentrated relief. Don’t let pain stop you in your tracks, use our heating pad patches to help you get back to your day. 

Our pain patch quickly relieves aches associated with the overuse of muscles and joints. Our patches can offer joint and muscle relief. 

Coralite pain patches can also be used for arthritis pain relief, strains, bruising and sprains. The discreet design can be used without making a mess and can be worn comfortably under your clothes. 

Powerful relief in a 4.88in X 3.31in size patch with camphor, methyl salicylate and menthol. Just one of our muscle soreness relief patches can offer pain relief for up to 8 hours. We recommend using one patch at a time. 

Coralite pain relief products are easy and convenient to use at home or on the go. Just clean and dry the area needing pain relief, remove the film from the back of the patch and apply it directly to the skin.

4.7 out of 5 - 110 global ratings

Very easy to apply and the heat sensation last for over 8 hours. My lower back pain is entirely replaced by a feeling of warmth.

9. Luminas Pain Relief Patch

- Fast Acting and Long Lasting, 24 Pack
- SAFE ALL-NATURAL PAIN RELIEF PATCHES target pain instantly to treat inflammation with no side effects
- DRUG-FREE & CHEMICAL-FREE patches for chronic pain, muscle cramp, joint pain and soreness
- WORKS FASTER & LASTS LONGER without medication, odors or discomfort
- EASY TO APPLY directly to area of pain for fast-acting pain relief that takes effect within minutes
- STAYS IN PLACE for up to 24 hours of muscle pain relief, lower back pain, shoulder pain and joint pain

The patches hold a small charge of electrons captured from ingredients known to reduce inflammation. Your bioelectric field induces the flow of electrons into your body to target the root of inflammation without side effects.

3.9 out of 5 - 872 global ratings

After traveling, walking what felt like 500 miles, my coccyx and knee were more painful than ever. My patches were waiting for me. 2 small on my knee, 2 more just above my tailbone with 70% relief in 30 minutes. I noticed my aching back isn't an issue. Although the swelling and pain in my knee isn't completely gone, these have provided more relief than ANYTHING including creams, gels and opioids. I will purchase these again and again for chronic pain since no doctor believes there is anything medically wrong.

10.  Sciaticream Nerve Pain Relief Cream - Best Topical Pain Relief for Sciatica

- Best Topical Pain Relief for Nerve Pain

Sciaticream Sciatica Nerve Pain Relieving Cream
The Sciatic nerve is the longest nerve in your body so even small twists or injury can lead to frustrating pain. Additionally, when a disk herniates, it might put pressure on the nerves around it. This can cause a lot of pain when that happens to be the sciatic nerve.

Here is where Vita Sciences Sciaticream can help you. As experts of neuropathy & nerve pain-relieving products, we formulated a natural formula that is scientifically targeted to relieve sciatica nerve pain while deeply soothing your skin.

Our sciatica nerve pain-relieving cream:
- prevents burning, tingling, numbness
- calms & gives quick relief from sciatica nerve pain
- uses natural ingredients and is quick to absorb

- Contains Arnica, B1, B5, B6, MSM. Soothing Aloe and Coconut Oil Base Fast Treatment for Sciatic Pain 
- Reduce Burning, Tingling, Numbness. 
- Airless dispenser provides metered dose.
- Odor Free
- Contains high doses of Vitamin B12 and Vitamin E. 
- Contains Vitamin B1, B5, & B6, MSM, Cetyl Myristoleate, Capsaicin and Andrographis extract that all work to lessen symptoms and support nerve health. and comfort
- Moisturizers and antioxidants allow this powerful cream to easily absorb into the skin.

3.7 out of 5 - 689 global ratings

Fantastic !!! Got this by accident. It was for someone else but Amazon told me to keep it. I will keep buying it. Two years ago I had a massive infection on my sciatic nerve and I spent two horrible weeks in the hospital while they tried to find the source of the worst pain I ever had. Of course I still have pain and this stuff works. It is also great for nighttime leg cramps


1. What Causes Chronic Knee Pain?

Temporary knee pain is different from chronic knee pain. Many people experience temporary knee pain as a result of an injury or accident. 

Chronic knee pain rarely goes away without treatment, and it isn’t always attributable to one incident. It’s most often the result of several causes or conditions.

Step 1 in dealing with a chronic knee pain is to know the cause or 'diagnosis', a term used by medical doctors. Treatment is step 2. This may appear logical but many people jump into various kind of treatments without even knowing the cause of the knee pain. Thus, wasting their hard-earned money in none effective treatments.

Physical conditions or diseases can cause knee pain. These include:
  • osteoarthritis: pain, inflammation, and joint destruction caused by degeneration and deterioration of the joint
  • tendinitis: pain in the front of the knee that is made worse when climbing, taking stairs, or walking up an incline
  • bursitis: inflammation caused by repeated overuse or injury of the knee
  • chondromalacia patella: damaged cartilage under the knee cap
  • gout: arthritis caused by the buildup of uric acid
  • Baker’s cyst: a buildup of synovial fluid (fluid that lubricates the joint) behind the knee
  • rheumatoid arthritis (RA): a chronic autoimmune inflammatory disorder that causes painful swelling and can eventually cause joint deformity and bone erosion
  • dislocation: dislocation of the kneecap most often the result of trauma
  • meniscus tear: a rupture in one or more of the cartilage in the knee
  • torn ligament: tear in one of the four ligaments in the knee — the most commonly injured ligament is the anterior cruciate ligament (ACL)
  • bone tumors: osteosarcoma (second most prevalent bone cancer), most commonly occurs in the knee
As you can see from the above, there are many causes of knee pain. That's why you need to understand the importance of 'diagnosis' or finding the cause of the knee pain. Knee pain due to gout or rheumatoid arthritis has to be treated differently from knee osteoarthritis. A mis-diagnosis will lead to a mis-treatment.

2. How Can I Get Rid of Inflammation Naturally?

- Anti-Inflammatory Diet

Researchers have identified certain foods that can help control inflammation. Many of them are found in the so-called Mediterranean diet, which emphasizes fish, vegetables and olive oil, among other staples.

There’s a standardized research tool that’s updated regularly that allows anybody to see if they’re eating foods we know cause chronic inflammation. This is called the The Dietary Inflammatory Index or DII. The choices of pro-inflammatory foods were initially based on studies showing that certain foods like trans-fatty acids (unsaturated fats) caused a spike in serum inflammatory markers in people.

- Autoimmune Protocol Diet

The Autoimmune Protocol (AIP) is a diet that aims to reduce inflammation, pain, and other symptoms caused by autoimmune diseases, such as lupus, inflammatory bowel disease (IBD), celiac disease, and rheumatoid arthritis (pubmed).

Many people who have followed the AIP diet report improvements in the way they feel, as well as reductions in common symptoms of autoimmune disorders, such as fatigue and gut or joint pain. Yet, while research on this diet is promising, it’s also limited.

The AIP diet is an elimination diet designed to help reduce inflammation or other symptoms caused by autoimmune disorders.

It’s comprised of two phases designed to help you identify and ultimately avoid the foods that may trigger inflammation and disease-specific symptoms. Research on its efficacy is limited but appears promising.

Due to its limited downsides, people with autoimmune disorders generally have little to lose by giving it a try. However, it’s likely best to seek guidance from a qualified health professional to ensure you continue to meet your nutrient needs throughout all phases of this diet.


Your doctor will likely recommend non-drug treatments if you have joint pain, and these recommendations may include supplements.

However, not all supplements are equally effective, and it’s essential to learn how to safely use them.

Before taking any supplements:
  • check first with your doctor that they are safe for you to use
  • get your supplements from a reputable source
  • follow the instructions provided
Other non-drug treatments can include:
  • trying to follow a healthy, balanced, and nutrient-dense diet
  • if you are over-weight, strive to loss weight 
  • find out the underlying cause of the joint pain. Could be from poor sitting or standing position.
  • physical therapy



Show more


Show more

Popular posts from this blog

12 Types of Zinc Supplementation and Absorption 2024

Fenbendazole Joe Tippens Protocol: A Step-by-Step Guide (2024)

Fenbendazole Cancer Success Stories and Treatment Testimonials: Case Series (2024)

Lumbrokinase vs Nattokinase vs Serrapeptase: What's the Difference?

10 Best Nicotinamide MonoNucleotide Supplements Review 2024

How to Detox Spike Protein After COVID (2024)

Top 10 Cancer Fighting Supplements 2024: Unveiling the Science Behind Cancer, Diet and Supplements (1,000+ Studies Analyzed)

NAC vs NAD vs NR vs NMN? What are the Differences?

The Surprising Potential of Ivermectin Against Cancer: Dr. Kathleen Ruddy (Transcript)

FLCCC I-MASK+ Protocol for COVID-19