Dr Richard Bartlett Inhaled Budesonide Protocol for COVID-19

In April 2021, The Lancet reported evidence of UK’s first effective drug to treat COVID-19 in patients at home, inhaled budesonide, showing the treatment can reduce recovery time by a median of three days. The treatment has since been included in clinical guidelines for treating early-stage COVID-19 across the UK, Canada and India.

Dr. Richard Bartlett shared with ACWT (America Can We Talk) about how asthma medicine Budesonide emptied a hospital ICU after being used to treat coronavirus. 

Inhaled budesonide is a safe, generic, inexpensive prescription medication that is being successfully used by millions of people who suffer from asthma every day. It can be prescribed by any doctor or nurse practitioner for respiratory symptoms or lung inflammation (FDA-approved). Budesonide is also available in some over-the-counter nasal sprays such as Rhinocort.

 

Richard Bartlett made waves in a July 2, 2020 interview (the video has been removed for violating YouTube's Community Guidelines) that already has racked up 4.1 million views online. In the interview, Bartlett, who has practiced medicine for 28 years and was part of former Texas Gov. Rick Perry’s Health Disparities Task Force, boasted a 100% survival rate for his patients since March 2020 by using his treatment strategy, centered around an inhaled steroid called budesonide.

“We have cracked the case,” the doctor said. He emphatically doubled down in an interview last week: “The cat is out of the bag. We have an answer for this. We don’t need another answer.”

Updates:

• Publication of the British trial (PRINCIPLE) of inhaled budesonide in outpatient, with 3 days faster recovery and a 25% reduction (8.8% vs 6.8%) in hospitalization/death (The Lancet, Aug 2021).
• Budesonide is widely known as an anti-inflammatory and not anti-viral. However, this study (Viruses - July 2021) demonstrated a dose-dependent inhibition of SARS-CoV-2 that was comparable between all viral variants tested and could indicate a multimodal mode of action of budesonide against SARS-CoV-2 and COVID-19, which could contribute to an improved clinical performance.
• COVID-19 is a highly dynamic topic. Please refer to the latest FLCCC protocol (constantly updated).

Well, with COVID-19, nothing has been that simple. But the “silver bullet,” as Bartlett called it, isn’t new at all, which is part of what makes it so intriguing. And despite very reasonable pushback from some sectors of the medical community, it’s worth a closer look.

For more than 20 years, doctors have prescribed budesonide, an anti-inflammatory, as preventive medicine for asthmatics. Inhaled corticosteroids, in fact, have been used for some time in patients of all ages, and very safely. On a theoretical basis, employing steroids to fight COVID-19 makes practical sense.

Dr. Richard Bartlett’s Protocol - Daystar Christian TV Network (September 2021)

The updated protocol below was given on The Daystar Christian TV Network on September 2021. Dr. Richard Bartlett on 9-14-2021 shares about the new treatment protocol being used to treat COVID and explains the impact it is having. If you want to watch this program online, click this link: https://player.lightcast.com/zMTO5IDO. This is an edited transcript.  

1. Budesonide – A steroid that decreases inflammation in the lungs. It has been out for 25 years and is FDA approved. For the budesonide, he recommends getting a portable nebulizer machine for $30-$40 where you place a pre-measured amount of the medicine in the nebulizer, push the button on, and do their breathing treatments once a day. It is readily available at a pharmacy by prescription.

2. Clarithromycin – An antibiotic that protects people from a bacterial pneumonia, both atypical pneumonia and strep-pneumonia.

3. Aspirin – A low-dose 81mg aspirin, a baby aspiring, is enough to protect the blood from clotting. One poison released from the lung tissues is called thromboxane that causes the increased clotting, heart attack, strokes, and clots in the lungs that are happening with some COVID-19 patients. 

4. Zinc also helps with viruses and can be purchased over the counter. (It helps to boost your immune system). 

5. Nose Spray – Budesonide comes in an over-the-counter form as a nose spray called Rhinocort also, which decreases the amount of receptors for the virus to latch on to. Walgreens has their own generic brand of Budesonide. You are doing this to kill some of the viral load so your system has less virus to fight. 

6. Mouthwash – Another recommendation is mouthwash such as Listerine to help kill some of the viral load. Some mouthwash kills 99.9% of germs such as bacteria and funguses, and it can slow the spread of viruses. This is the kind you want to get. Gargle only twice a day. For more information, click the following link to read the article, “To Disrupt the COVID-19 Virus, Gargle and Rinse!” https://www.healthleadersmedia.com/covid-19/disrupt-covid-19-virus-gargle-and-rinse.

Medical Journal Articles or Studies

Below are links to a peer-reviewed studies, articles in medical journals, or news articles regarding the efficacy of budesonide.

• Database of Budesonide COVID-19 studies (constantly updated)
• ProLung™-budesonide Inhibits SARS-CoV-2 Replication and Reduces Lung Inflammation (Konduri et al., bioRxiv)
• Inhaled budesonide for COVID-19 in people at higher risk of adverse outcomes in the community: interim analyses from the PRINCIPLE trial (Yu et al., medRxiv)
• Common asthma treatment reduces need for hospitalisation [by 90%] in COVID-19 patients, study suggests (University of Oxford)
• Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection – ScienceDirect (from the American Journal of Medicine)
• Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19) (Reviews in Cardiovascular Medicine)
• Inhaled corticosteroids and COVID-19: a systematic review and clinical perspective (from European Respiratory Journal)
• Inhaled corticosteroids in virus pandemics: a treatment for COVID-19? (From The Lancet)
• SARS-CoV-2 and The Case for Empirical Treatment (The Global Journal of Science Frontier Research – Volume 20, Issue 4)
• Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection (US National Library of Medicine National Institutes of Health)
• Budesonide facilitates weaning from mechanical ventilation in difficult-to-wean very severe COPD patients (US National Library of Medicine National Institutes of Health)
• Effect of nebulized budesonide on respiratory mechanics and oxygenation in acute lung injury/acute respiratory distress syndrome (US National Library of Medicine National Institutes of Health)

News Reports & Studies

• Common asthma drug cuts COVID-19 hospitalization risk, recovery time – Oxford study (Reuters)
• Common asthma drug cuts need to send Covid patients to hospital by 90 per cent and shortens recovery time, Oxford University scientists say (The Daily Mail)
• Common asthma drug can reduce COVID hospitalizations by 90% — study (The Times of Israel)
• Common asthma drug slashes Covid hospitalisation by 90%, experts say (The Sun)
• Coronavirus: Inhaling this can reduce COVID severity by 90 per cent, claims study (The Times of India)
• University of Oxford Does it Again! Now Showing that AstraZeneca’s Pulmicort Reduces COVID-19 Hospitalization Rate by 90% (Trial Site news)
• Common asthma treatment reduces need for hospitalization in COVID-19 patients, study suggests (Medical Express)
• Study finds that inhaled budesonide can reduce severity of and speed recovery from COVID-19 (OINDP News)
• Some Texas Doctors Are Treating COVID Patients With A ‘Silver Bullet’ Drug (Texas Standard)
• Is a new steroid treatment a miracle solution for COVID-19—or is it snake oil? (Fortune Magazine)

Below are links to studies or articles about the efficacy or success of some of the other remedies we recommend for prevention and treatment.

• Betadine (Povidone Iodine) and Coronavirus
• Mouthwash eliminates coronavirus in 30 seconds… in the lab (BBC Science Focus)
• Library of Articles and Studies on the success of the H2Bev drinks (H2Bev website)
• Vitamin D can help reduce coronavirus risk by 54%: Boston University doctor (Boston Herald
• Iota-Carrageenan Nasal Spray in the prophylaxis of COVID-19 (Betadine Cold Defence Nasal Spray)
• Nitric Oxide Nasal Spray and COVID-19

Clinical Research

There are several open-label studies currently open to recruitment examining the role of inhaled budesonide in COVID-19 infection (ISRCTN86534580, NCT04355637, NCT04331054) and others investigating the role of inhaled ciclesonide (NCT04330586, NCT04377711, NCT04381364, NCT04356495); whether these studies also show an effect on long COVID will be of importance.

Editor's Note and Key Takeaway

Two recent Randomized Controlled Trials (STOIC 2021, PRINCIPLE 2021) have demonstrated more rapid symptomatic improvement in ambulatory patients with COVID-19 treated with inhaled budesonide, however, there was no difference in the rate of hospitalization. It should be noted that both these studies were open label (no placebo in the control arm) and that the primary end-point was subjective (time to symptom resolution). Corticosteroids downregulate the expression of interferons (hosts primary antiviral defenses) and downregulated ACE-2 expression (harmful). 

Furthermore, two population level studies (Lancet Resp Med 2021, OpenSAFELY 2021) suggest that inhaled corticosteroids may increase the risk of death in patients with COVID-19. Based on these data the role of inhaled corticosteroids in the 'early phase' of COVID-19 is unclear. 

There is also a common confusion between 'inhaled' budesonide and 'nasal spray' budesonide. They are not the same. Nasal sprays are meant for the nose and is commonly used for allergic rhinitis. However, for the drug to get to the lungs, budesonide needs to be in an inhalation device (e.g. Pulmicort Turbohaler).

Related: 

• List of Doctors that will prescribe Ivermectin or Budesonide

• List of Pharmacies that will fill Ivermectin or Budesonide

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