Zelenko Protocols: COVID-19 Prophylaxis and Treatment (2022)
What is the Zelenko protocol? The Zelenko COVID-19 Protocol was developed by Dr Vladimir Zelenko. A retrospective study analyzing Dr Zelenko's patient data was accepted for publication in the International Journal of Antimicrobial Agents after a rigorous peer review process. The study finds that early intervention and treatment of high-risk patients with COVID-19 resulted in significantly fewer hospitalizations and deaths. The treatment consisting of zinc, low-dose hydroxychloroquine (HCQ), and azithromycin, is also referred to as "The Zelenko Protocol." Dr Zelenko has since updated his protocols to incorporate new evidence.
Update: Recently, Ivermectin has come to the fore as a more effective (also long standing, cheap, generic drug), in all three stages of COVID-19. Dr Zelenko has also updated his protocols to incorporate ivermectin as an option for both the prophylactic and treatment protocols as shown below.
Introduction
This webpage compiles content related to the early outpatient treatment protocol that has been proposed by Dr. Vladimir Zelenko for the SARS-CoV-2 virus. Dr. Zelenko originally risk-stratified patients and treated high-risk patients with hydroxychloroquine, zinc, and azithromycin.Zelenko Covid-19 Prophylaxis Protocol
Low Risk Patients - Young healthy people do not need prophylaxis against COVID-19. In young and healthy people, this infection causes mild cold-like symptoms. It is advantageous for these patients to be exposed to Covid-19, build up their antibodies and have their immune system clear the virus. This will facilitate the development of herd immunity and help prevent future Covid-19 pandemics. However, if these patients desire prophylaxis against Covid-19, then they should take the protocol noted below.
Moderate Risk Patients - Patients from this category are healthy but have high potential viral-load exposure. This group includes medical personnel, caregivers of high-risk patients, people who use public transportation, first responders and other essential personnel who are crucial to the continued functioning of society. These patients should be encouraged to take prophylaxis against Covid-19 in accordance with the protocol noted below.
High Risk Patients - Patients are considered high risk if they are over the age of 45, or if they are younger than 45 but they have comorbidities, that is, they have other health conditions that put them at risk. These patients have between a 5 to 10% mortality rate if they are infected with Covid-19. These patients should be strongly encouraged to take prophylaxis against Covid-19 in accordance with the protocol noted below.
- Zinc (elemental) 25mg 1 time a day (PubMed) (Amazon) (iHerb)
- Vitamin D3 5000 iu 1 time a day (vdnmeta.com) (Amazon) (iHerb)
- Vitamin C 1000 mg 1 time a day (PubMed) (Amazon) (iHerb)
- Quercetin 500mg 1 time a day (Amazon) (iHerb)
- Hydroxychloroquine (HCQ) 200mg once a day for 5 days, then HCQ 200 mg one time a week (ScienceDirect) (Find a Doctor)
- Vitamin D3 5000 IU/day for 5 days (Amazon)
- Zinc 25 mg/day (Amazon) | How much zinc to take with hydroxychloroquine?
- Zinc is critical. It helps block the virus from multiplying. Hydroxychloroquine is the carrier taking zinc INTO the cells to do its job.
- Vitamin D3: Preferable in oil capsules for better absorption.
- Inorganic zinc such as zinc sulfate, is not as effective or useable by your body as chelated zinc sources. Zinc lozenges are preferred so that the tissues of the nose and throat are rich in zinc as soon as they encounter the virus
Zelenko Protocol - Treatment Plan for Patients with Covid-19 symptoms
Fundamental Principles (Dr Zelenko Protocol When to Start)
Patient Categories
Low risk patient - Younger than 45, no co-morbidities, and clinically stableHigh risk patient - Older than 45, younger than 45 with co-morbidities, or clinically unstable
Treatment Options
Low risk patients - over the counter options:
1. Elemental Zinc 50mg 1 time a day for 7 days (PubMed) (Amazon)
2.1. Quercetin 500mg 2 times a day for 7 days (PubMed) (Amazon) OR
2.2. Epigallocatechin-gallate (EGCG) 400mg 1 time a day for 7 days (J. Agric. Food Chem. 2014)
4. Vitamin D3 5000iu 1 time a day for 7 days (Amazon)
Editor's Note on Vitamin D3: Preferable in oil capsules for better absorption.
Hydroxychloroquine (HCQ) 200mg 2 times a day for 5-7 days (ScienceDirect)
and/or
Ivermectin 0.4-0.5mg/kg/day for 5-7 days (ivmmeta.com). (Find a Doctor)
Either or both HCQ and IVM can be used, and if one only, the second agent may be added after about 2 days of treatment if obvious recovery has not yet been observed etc.
If HCQ is not available, Quercetin 500mg 3 times a day for 7 days OR EGCG 400mg 2 times a day for 7 days
1. Elemental Zinc 50 - 100 mg 1 time a day for 7 days (Amazon)
2. Hydroxychloroquine (HCQ) 200mg 2 times a day for 7 days3. Azithromycin 500mg 1 time a day for 5 days OR Doxycycline 100mg 2 times a day for 7 days
4. Vitamin C 1000 mg 1 time a day for 7 days (Amazon)
5. Vitamin D3 10,000 IU 1 time a day for 7 days (Amazon)
- If you simply cannot get hydroxychloroquine or ivermectin, quercetin is a viable stand-in. Quercetin works best when taken with vitamin C and Bromelain, as vitamin C helps activate it and bromelain helps with the absorption.
- Dexamethasone 6-12mg 1 time a day for 7 days OR Prednisone 20mg twice a day for 7 days, taper as needed (not suitable during viral phase)
- Budesonide 1mg/2cc solution via nebulizer twice a day for 7 days (not suitable during viral phase)
- Blood thinners (i.e. Lovenox, Eliquis, Xarelto, Pradaxa, Aspirin) (Amazon)
- Colchicine 0.6mg 2-3 times a day for 5-7 days (MedRxiv 2021)
- Monoclonal antibodies
- Home IV fluids and oxygen
- Curcumin: 500 mg twice a day (Ref) (Amazon)
- Fluvoxamine: 50 mg twice daily for 10–14 days. Add to ivermectin if: 1) minimal response after 2 days of ivermectin; 2) in regions with more aggressive variants; 3) treatment started on or after day 5 of symptoms or in pulmonary phase; or 4) numerous co-morbidities/risk factors. Avoid if patient is already on an SSRI (selective serotonin reuptake inhibitor).
- If you can’t get fluvoxamine (Luvox), using 30mg once a day of fluoxetine (Prozac) is equally effective (equivalent to 50mg twice a day of fluvoxamine).
- Pulse Oximeter: Monitoring your oxygen saturation with a pulse oximeter and to go to the hospital if you get below 94%. (Amazon)
- Mouthwash: 3 x daily – gargle (do not swallow) antiseptic mouthwash with cetylpyridinium chloride (e.g. Crest, Scope mouthwash™), ListerineTM with essential oils, or povidone/iodine 1 % solution as alternative (Betadine® Antiseptic Sore Throat Gargle™). (Ref)
- Nasal Spray: Xlear Nasal Spray with Xylitol (Ref) (Amazon)
- Aspirin: 325 mg/day unless contraindicated. (Amazon) (not suitable during viral phase)
- Bromhexine 8 mg three times a day (Ref) (Lazada Malaysia*)
About Dr Vladimir Zelenko
He graduated with a B.A. degree with high honors in Chemistry from Hofstra University. After receiving an academic scholarship to attend S.U.N.Y. at Buffalo School of Medicine, he earned his M.D. degree in May 2000. Dr. Zelenko completed his family medicine residency at South Nassau Communities Hospital in Oceanside, N.Y. in May 2004. Since then, Dr. Zelenko has practiced family medicine in New York’s Hudson Valley. He has been described by his patients as like a family member to thousands of families, and is a medical adviser to the volunteer ambulance corps in Kiryas Joel, New York.
When asked about studies that seemed to discredit the efficacy of
HCQ in treating the Chinese coronavirus, Zelenko explained “You don’t fire a gun without a bullet in it and then say the
gun doesn’t work when you don’t kill the target. The studies that
were done on HCQ did not include the use of Zinc. HCQ is what
opens the cell and enables Zinc to attack the virus. One is not
effective without the other, or without a suitable substitute for
HCQ. The studies were designed to fail.”
Dr. Zelenko says
that both prophylaxis measures and actual case treatments need to be
customized to the individual. As a general rule, he says, those
people who are in the higher risk groups, both by age and by other
pre-existing conditions, require more aggressive actions on both the
preventative and diagnostic side.
“This virus remains
relatively stable inside the host for about the first five days,”
Zelenko says. “After that it starts to multiply rapidly. It also
starts to migrate from sinus to lungs and cardio areas where
involvement becomes more severe and treatment becomes more
difficult. The key is early intervention.” Zelenko again
mentioned his 84% success rate in high-risk patients.
Related Scientific Papers
- Nov 25, 2021: Remarkable results from Turkish randomized trial of 237 hospitalized Covid patients treated with Hydroxychloroquine + Azithromycin + Zinc standard of care +/- high-dose IV vitamin C.
- R. Derwand, M. Scholz, "Does zinc supplementation enhance the clinical efficacy of chloroquine/hydroxychloroquine to win today's battle against COVID-19?", Medical Hypotheses 142 (2020), 109815
- Scholz, M.; Derwand, R.; Zelenko, V. "COVID-19 outpatients - early risk-stratified treatment with zinc plus low dose hydroxychloroquine and azithromycin: a retrospective case series study", International Journal of Antimicrobial Agents 56 (2020), 106214 [press release]
- Peter A. McCullough, Ronan J.Kelly, Gaetano Ruocco, Edgar Lerma, James Tumlin, Kevin R.Wheelan, Nevin Katz, Norman E.Lepor, Kris Vijay, Harvey Carter, Bhupinder Singh, Sean P.McCullough, Brijesh K.Bhambi, Alberto Palazzuoli, Gaetano M.De Ferrari, Gregory P.Milligan, TaimurSafder, Kristen M.Tecson, Harvey A.Risch: "Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection", The American Journal of Medicine 134 (2020), 16-22
- Peter A. McCullough, Paul E. Alexander, Robin Armstrong, Cristian Arvinte, Alan F. Bain, Richard P. Bartlett, Robert L. Berkowitz, Andrew C. Berry, Thomas J. Borody, Joseph H. Brewer, Adam M. Brufsky, Teryn Clarke, Roland Derwand, Alieta Eck, John Eck, Richard A. Eisner, George C. Fareed, Angelina Farella, Silvia N. S. Fonseca, Charles E. Geyer, Jr., Russell S. Gonnering, Karladine E. Graves, Kenneth B. V. Gross, Sabine Hazan, Kristin S. Held, H. Thomas Hight, Stella Immanuel, Michael M. Jacobs, Joseph A. Ladapo, Lionel H. Lee, John Littell, Ivette Lozano, Harpal S. Mangat, Ben Marble, John E. McKinnon, Lee D. Merritt, Jane M. Orient, Ramin Oskoui, Donald C. Pompan, Brian C. Procter, Chad Prodromos, Juliana Cepelowicz Rajter, Jean-Jacques Rajter, C. Venkata S. Ram, Salete S. Rios, Harvey A. Risch, Michael J. A. Robb, Molly Rutherford, Martin Scholz, Marilyn M. Singleton, James A. Tumlin, Brian M. Tyson, Richard G. Urso, Kelly Victory, Elizabeth Lee Vliet, Craig M. Wax, Alexandre G. Wolkoff, Vicki Wooll, Vladimir Zelenko."Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19)", Reviews in Cardiovascular Medicine 21 (4) (2020), 517-530
- Brian C. Procter, Casey Ross, Vanessa Pickard, Erica Smith, Cortney Hanson, Peter A. McCullough. "Clinical outcomes after early ambulatory multidrug therapy for high-risk SARS-CoV-2 (COVID-19) infection", Reviews in Cardiovascular Medicine 21 (4) (2020), 611-614
Documents from Dr. Zelenko
- 03/23/2020: Dr. Zelenko's open letter to the medical professional community. [pdf] || [original link] || [tinyurl]
- 04/28/2020: Dr. Zelenko's second open letter to the medical professional community. [pdf] || [original link] || [tinyurl]
- 06/14/2020: Dr. Zelenko's letter to the Israeli government [pdf] || [original link] || [tinyurl]
- 07/15/2020: Dr. Zelenko's open letter to the White House [pdf] || [original link]
- 08/23/2020: Dr. Zelenko's updated treatment protocol. [pdf] || [original link] || [tinyurl] || (presentation: [youtube link]) || (another presentation: [bitchute link])
- 08/23/2020: Dr. Zelenko's prophylactic protocol. (updated 02/08/2021) [pdf] || [original link] || [tinyurl]
- 10/27/2020: Press Release: Data Based On Zelenko Protocol Passes Peer Review [pdf] || [original link]
- 11/22/2020: Dr. Zelenko's Protocol Plus chart. [pdf] || [original link]
- 11/26/2020: Dr. Zelenko's updated treatment protocol. (2nd update); (3rd update: 02/08/2021) [pdf] || [original link] || [tinyurl]
- 11/23/2020: Dr. Zelenko's second open letter to the White House [pdf] || [original link]
- 12/02/2020: Dr. Zelenko's statement to the U.S. Senate Committee on Homeland Security [pdf] || [original link]
- 12/23/2020: Dr. Zelenko's third open letter to the White House [pdf] || [original link]
- 01/20/2021: Choose Truth and Choose Life [pdf] || [original link]
- 01/22/2021: Nebulized Hydroxychloroquine for COVID-19 Treatment: 80x Improvement in Breathing [pdf] || [original link]
- 02/23/2021: Plan to Reopen Israel [pdf] || [original link]
- 02/23/2021: Dr. Zelenko's updated treatment protocol. [pdf] || [original link]
- 02/23/2021: Dr. Zelenko's prophylactic protocol. [pdf] || [original link]
Video updates from Dr. Vladimir Zelenko
04/19/2020: Dr. Zelenko on the latest statistical clinical outcomes of his treatment.
[youtube link] (censored) ||[bitchute]
04/30/2020: Dr. Zelenko responds to the VA study and his plans to publish his data in observational peer-reviewed research papers.
[youtube link] (censored) ||[bitchute]
11/15/2020: Dr. Zelenko provides an update on the current political situation and also on an upcoming Senate hearing by Senator Ron Johnson on early treatment. Also comments on the necessary general public health policy, mask mandates, antibofy and t-cell immunity testing, quarantine policies, the importance of adapting treatment protocols to individual patients, and the vaccine. This is a must-watch interview.
[youtube link] || [bitchute]
12/30/2020: Dr. Zelenko announces his new website, in response to censorship by twitter. Also comments on the vaccine, reinfections, and the new mutation of the SARS-CoV-2 virus, and t-cell immunity. Note that the youtube version is abbreviated, to avoid censorship.
[youtube link] || [facebook] || [bitchute]
01/24/2021: Say No to Covid-19 Anxiety.
[youtube link] || [bitchute]
02/01/2021: Dr. Zelenko's brief statement on the covid vaccines
[youtube link] || [bitchute]
02/01/2021: Dr. Zelenko's statement on the Israeli vaccine policy
[facebook] || [bitchute]
[youtube] || [bitchute]
[youtube link] || [bitchute]
12/09/2020: Dr. Zelenko curing Covid19 patients without fanfare! (interview by Dr. Carole Lieberman)
[voiceamerica]
12/14/2020: Dr. Zelenko interview by Patriot Transition
[youtube link] || [bitchute]
12/16/2020: Dr. Zelenko interview by Patriots in Tune
[youtube] (censored) || [bitchute]
12/16/2020: Dr. Zelenko interview by Del Bigtree
[bitchute]
12/16/2020: Dr. Zelenko interview by John Mappin
[youtube] || [bitchute]
12/23/2020: Red Dawn News interview w/ Dr. Zelenko Pt 1 of 2
[youtube link] || [rumble] || [bitchute]
12/25/2020: Talkline With Zev Brenner Interviews Dr. Zev Zelenko
[youtube link]
12/26/2020: Dr. Zev Zelenko on Covid-19 Vaccination Tyranny and Dangers
[worldviewweekend]
12/27/2020: Red Dawn News interview w/ Dr. Zelenko Pt 2 of 2
[youtube link] || [bitchute]
01/08/2021: Dr. Zelenko: Steps can be taken to reduce deadliness of COVID-19
[newslink]
01/08/2021: Dr. Zelenko 2nd interview with the TCN TV Network
[brighteon]
01/28/2021: Dr. Zelenko: Interview with Dr. Peter Breggin. This is a very profound interview and should be watched more than once.
[youtube link] || [bitchute] || [newtube]
02/06/2021: Dr. Zelenko's interview with Laura Eisenhower
[bitchute]
02/26/2021: ASIA PACIFIC TODAY. Early treatment of Covid-19 saves lives with Dr Vladimir Zelenko.
[rumble]
02/25/2021: An amazing interview with Leah Wilson by Dr. Peter Breggin: Finding the Courage to be True to Yourself and America
[youtube] || [bitchute]
[youtube link] || [bitchute]
12/04/2020: The FLCCC Alliance press conference from Houston, Texas
[youtube link]
12/10/2020: Dr. Peter McCullough interview with Dr. Peter Breggin: Peter A. McCullough, MD, MPH--Save Yourself, Your Family, the World From COVID-19
[youtube link] || [bitchute]
12/22/2020: Dr. Peter McCullough interview with Dr. Peter Breggin
[youtube link] || [bitchute]
01/16/2021: Bioweapons expert Dr. Lee Merrit Interview on SARS-CoV-2
[youtube link] || [bitchute]
02/03/2021: Panel of medical doctors and researchers discuss Covid-19 protection, treatments, cures, and the vaccines.
[rumble] || [bitchute]
02/11/2021: Dr. Simone Gold interview on experimental mRNA vaccines and their safety
[youtube]
02/13/2021: ASIA PACIFIC TODAY. Early treatment for Covid-19 reduces deaths with Dr Peter Mccullough
[rumble]

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