6 Best Prebiotic and Probiotic Combination for Weight Loss 2023

Probiotics are a combination of live microorganisms, while prebiotics are non-digestible food ingredients. Both probiotics and prebiotics are essential for digestive health and overall wellness. Probiotics help to promote the growth of beneficial bacteria in the gut, while prebiotics can help to feed those beneficial bacteria and support a healthy balance of bacteria in the digestive tract. 

What Strain of Probiotic Is Best for Weight Loss?

Lactobacillus Gasseri

Lactobacillus gasseri, of all the probiotic bacteria examined so far, shows some of the most promising weight-loss effects. It has been shown in numerous animal experiments that it has anti-obesity properties.

In addition, studies in adults have also shown encouraging results. According to a study, probiotic Lactobacillus gasseri showed lowering effects on abdominal adiposity, body weight and other measures in adults with obese tendencies.

Another study was conducted using 210 healthy Japanese adults with significant amounts of belly fat who were asked to consume Lactobacillus gasseri for 12 weeks.

As result, BMI, waist and hip circumferences, and body fat mass were significantly decreased. Moreover, belly fat was also reduced by 8.5%. However, this study also suggests that constant consumption might be needed to maintain the effect.

What Probiotic Strain Causes Weight Gain?

Keep in mind that one probiotic should not be considered the same as another, there's many different probiotic strains out there. It has been shown that some probiotic strains may actually cause weight gain.

A study suggests that lactobacillus acidophilus administration resulted in significant weight gain in humans and in animals. Moreover, Lactobacillus fermentum and Lactobacillus ingluviei were also associated with weight gain in animals.

Does Prebiotics Help Weight Loss?

The best prebiotics for weight loss are those that contain high levels of dietary fibers, such as inulin, oligofructose, and resistant starch. Fiber can help to reduce hunger and give the sensation of being full, which may be beneficial for weight loss. 

Moreover, independent of other lifestyle changes, one study suggests oligofructose supplementation has the potential to promote weight loss and improve glucose regulation in overweight adults.

Another study also suggest inulin-enriched diet is able to promote weight loss in obese patients, the treatment efficiency being related to gut microbiota characteristics.

How to Take Probiotics and Prebiotics for Weight Loss

When is the Best Time to Take Probiotics and Prebiotics?

In addition to taking a probiotic supplement for weight loss, you need to follow all the healthy things, for instance:

a. Don’t skip breakfast
A balanced breakfast is essential for weight loss since it helps to supply the right balance of nutrients to keep your body nourished and operating as it should.Moreover, breakfast helps to regulate your appetite and reduce cravings throughout the day, which can help to prevent overeating.

b. Eat a nutritious diet
Include a variety of vegetables, fruits, high-fiber whole grains, legumes, and healthy fats in your diet. Reduce the amount of sugar and refined carbs in your diet. Cut down on alcohol and junk food.

c. Increase your physical activity or exercise
Physical activity is essential for losing weight. Exercise can aid in the burning of excess calories that cannot be lost by diet alone. Not only for weight management, exercise can give you many other health benefits!

d. Take control of your stress
Learn stress-relieving techniques, for instance yoga, meditation, etc.

e. Get adequate sleep
Getting adequate, quality sleep is also important part of a healthy weight loss plan. In a study of people undergoing 14 days of calorie restriction, the participants lost less fat when they spent 5.5 h a day in bed than when they spent 8.5 h a day in bed

Best Prebiotic and Probiotic Combination for Weight Loss

1. Physician's CHOICE Probiotics for Weight Loss Management

- Supports Weight Loss 
In a Clinical study, 100 patients lost an average of over 30 lbs. in 90 days taking 300 mg of stimulant-free Greenselect Phytosome daily with a reduced-calorie diet & exercise. Greenselect is a green tea caffeine free extract

- Supports Gut & Bloating
Contains Probiotics & organic prebiotics with natural green tea extract. With our weight management probiotics you can be assured that our formula has been formulated to you on your weight management journey

- Supports Digestive Health & Balance
A daily probiotic and organic prebiotic with digestive enzymes to promote gut health and balance. These strains act together in supporting gut health. Our formula contains Capsimax to help promote weight management

- Probiotics to Support Weight Loss Management for Women & Men
Our probiotic for women & men is designed to support weight loss management & digestive health. Thin30 is a useful diet aid that is a great addition to your diet & exercise regimen.

- Safety Assured Standard of Quality
Our Probiotic is 3rd-party tested for purity, manufactured in the USA using imported and domestic ingredients in a cGMP compliant facility. Our probiotics for women & men for weight loss management are non-GMO

4.1 out of 5 - more than 15,100 global ratings

I purchase this probiotic 3 times because of how I like it! I wanted to lose some stubborn weight and also help me with overall gut health. I started taking it and felt better almost instantly. After taking it for a month I saw flatter stomach and I was happy. After two months I actually saw myself leaner and thinner in the mirror. Well, I do watch my diet of course, but I think that this probiotic is a great aid in weight loss. Keep buying!

2. Garden of Life Dr. Formulated Probiotics Fitbiotic

- Digestion Support
This 50 billion CFU once daily probiotic supplement includes L gasseri and L rhamnosus clinically studied for weight loss support, acidophilus for digestive health, constipation relief, immune system health and more

- Weight Loss Supplement
Once daily probiotic dietary supplement helps and support satiety with 4g of organic fiber

- Probiotic and Prebiotic Supplement
This prebiotic and probiotic supplement contains organic Acacia (A. Senegal) fiber to help good bacteria thrive

- Shelf Stable Probiotics
This 50 billion probiotics supplement comes in 20 one daily packets; no refrigeration required

- Organic Diet Probiotic
Our probiotic for men or women is dairy free, gluten free, soy free, certified organic, vegetarian, and sugar free

4.4 out of 5 - more than 900 global ratings

I am always fighting my weight and this probiotic from the well respected Garden of Life company is especially formulated to help support the body during weight loss. To my surprise these are not capsules but powder you mix with water to make an almost tasteless drink. 

Fiber is added to help the dieter fill full. Digestive problems often crop up when making changes in diet so this probiotic is particularly appreciated. Garden of Life is currently marketing specially targeted probiotics to women and men over and under fifty, for mood stability, pregnant and nursing mothers and so forth.

3. Surebounty 14-Day Cleanse Probiotic, Prebiotics

- Digestive Cleanse & Detox*
Surebounty Probiotic features full-spectrum digestive enzymes to break down the hard-to-digest buildup inside your body.* Includes High Fiber Complex to gently flush your GI tract of excessive waste & toxins, promoting healthy bowel movements.* The highest verified CFU count 200 billion helps quickly repopulate intestinal flora and maintain digestive function.* Take TWO caps daily, Feel Cleansed and Leaner with Surebounty 14-Day Cleanse Probiotic.*

- From Clogged to Cleansed*
Gaining weight and you don't know why? Feeling sluggish and fatigue? Have distended, bloated stomachs? If you are struggling with these issues, you’ve come to the right place. Surebounty 14-Day Cleanse Probiotic is designed to reset the microbiome and cleanse the digestive tract within 14 days.* Quick nourishment for increased regularity, refreshed energy, reduced bloating, and a flatter abdomen.*

- No Allergens or Nasties:
NO GMOs, soy, gluten, milk, sugar, egg, wheat, corn, nut, fish, shellfish. And never will you find Nasties like artificial ingredients, fillers, binders, or preservatives in Surebounty!

I didn't realize how well they were working, until running out. I ordered more quickly.

4. EndoMune Metabolic Rescue Prebiotic and Probiotic

- Promote Health Weight Loss
Our natural blend of the prebiotics Xylooligosaccharides (XOS) and Bifidobacterium lactis stimulates the release of specific hormones that often result in a decreased appetite, which in turn promotes healthy weight loss and optimal blood sugar levels. 

- Support Healthy Glucose and Cholesterol Levels
XOS nourishes the bifidobateria which in turn releases beneficial hormones to promote healthy blood sugar and cholesterol levels, keys to maintaining overall good health and metabolism

- Formulated by A Doctor Using Data and Research
EndoMune Metabolic Rescue was developed by a Gastroenterologist and is a unique and perfect Prebiotic and Probiotic blend. The shelf stable vegan capsule contains no dairy, no GMOs, no gluten, and no shellfish ingredients. It is certified Kosher

- A Happier, Healthier You
The gut-brain axis (GBA) is bidirectional communication between your brain and gut through signaling from gut-microbiota to your brain. Additionally, 95% of serotonin, a mood stabilizer is produced in the gut. Research suggests that the probiotic bifidobacteria may be part of the delivery system for these neuroactive compounds leading to a happier you

I like how fast it works and stays constant. I can tell if I don’t use it for a few days, my gut feels off. I will continue to use it. It has helped with my weightloss as well.

5. New Chapter Weight Management Probiotic

- The Most Advanced Probiotics
Delivers powerful probiotics in clinically studied amounts that support weight management and help you meet your healthy lifestyle goals*

- Immune & Digestion Support
One daily probiotic boosts immune defenses and promotes digestive health, enhancing your gut’s ability to absorb nutrients from food*

- Prebiotics & Probiotics + Targeted Herbs
Green Coffee Bean & Hibiscus are thermogenic (fat-burning) herbs known to boost metabolism and invigorate the body,* also includes prebiotic fiber to fuel the live probiotics

- Shelf-stable Until Expiration
No refrigeration needed. Dairy Free, Non-GMO Project Verified, 100% Vegan, DNA tested for identity, Gluten Free, No Added Sugar or Sweeteners, No Synthetic Fillers, No Artificial Colors or Flavors

I'm older and I need all of the digestive support I can get. My digestive enzymes might not be functioning to the degree they once did. L. acidophilus is a probiotic bacteria that naturally occurs in the human gut and other parts of the body. This bacteria helps the digestive system break down sugars. This has 10 billion CFU of lactobacillus cultures. It also has chaste tree berry extract, organic maca root extract and organic lavender extract and inulin from organic Jerusalem artichoke root.

Let's say that I feel these are helping me, not hurting, especially with digestion. And then, there's the added benefit of the hormone balance proprietary blend. I've been taking these, my energy is good and I feel good.

This is a product that I would buy and probably will buy in the future.

6. MaryRuth Organics Probiotics Weight Management 

- Probiotic Weight Management+
Support healthy weight with our Probiotic Weight Management+ capsules. These capsules were formulated with a blend of probiotic strains and botanicals, that were made to promote gut health and support your overall weight management goals!

- Multiple Benefit
Garcinia cambogia, a tropical fruit native to Southeast Asia, MorosilTM, the extract of Moro red oranges (Citrus sinensis), and Green Tea leaf help support a healthy weight. The probiotics, Lactobacillus plantarum, Lactobacillus casei, and Lactobacillus acidophilus, are included to support your gut health and gut biome.

- Just Two Capsules Per Day
Adults take two capsules per day with water. Can be taken with or without food. While our weight management probiotic capsules are shelf-stable, refrigeration may lengthen shelf life. Support your gut and help maintain a healthy weight with these capsules today.

4.3 out of 5 - more than 2,100 global ratings

Hey guys! I've been using Mary Ruth's Probiotic Weight Management pills for about 1 month now and Im really impressed! These pills are completely Vegan, non GMO. I usually take 2, 1 before I eat breakfast in the morning and the second one later on in the day. I have lost 11lbs since I've been taking them. I will continue to use more of there products because they are all Natural and gives me more energy!


a. What Food is Highest in Probiotics?

Yogurt is rich in probiotics, you can also find probiotics in fermented foods such as kimchi, sauerkraut, tempeh, kefir, and miso.

b. What Food is Highest in Prebiotics? 

Foods that are rich in prebiotics include onions, garlic, leeks, asparagus, bananas, oats, apples, wheat, barley, and flaxseeds.

c. Signs You Need Probiotics

Digestive irregularity
Your metabolism is a bit slow
You’ve taken an antibiotic, even if it was a long time ago. Antibiotic can kill both bad and good bacteria, as the result, you may need probiotic to balance your gut bacteria.
You’ve got some skin issues like eczema, psoriasis, and itchy rashes

Above all, these symptoms are not always linked to a lack of probiotics. Best to talk with your doctor for a diagnosis.

d. How Do You Know If Probiotics Are Working?

When you take a high-quality probiotic supplement, you may feel a variety of benefits in your body, from better digestion and energy to a better mood and clearer skin. Improved digestion is frequently the first and most noticeable change people will notice.

The probiotic bacteria help to restore your gut flora, which can enhance things like bowel movement frequency and regularity while also reducing bloating and gas.

e. Connection Between Probiotics and Antibiotics

There are already good and bad bacteria live in your body. The good bacteria help keep you healthy, by boosting your immune system and preventing illness.

Bad bacteria, on the other hand, can get in and cause illness. Antibiotics can kill bad bacteria, but they usually kill a lot of healthy bacteria as well. This is where probiotics can help, by balancing your gut bacteria.

f. Can You Take Probiotics While Taking Antibiotics?

If you want to take a probiotic while consuming an antibiotic, you can start it the same day you start the antibiotic. But you must take them at different time. After consuming antibiotics, wait at least two hours before taking a probiotic.

Probiotics are usually taken on an empty stomach. They should be continued for at least a few weeks after your antibiotic treatment is ended, though some people take probiotics on a daily basis to not only aid digestion but also to boost their immune system and improve nutritional absorption.



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