10 Best Supplements to Fix Brain Fog 2023

It’s common to experience occasional brain fog, especially when a person can identify a specific cause, such as being exhausted, being sick, or experiencing stress at home. However, people should visit a doctor if: brain fog is disturbing your everyday routine or making it difficult to perform daily tasks.

If left untreated, brain fog can decrease your quality of life and increase your risk for Alzheimer’s disease, Parkinson’s disease, and memory loss.

Causes of Brain Fog

There are numerous reasons why brain fog occurs. The problem can be fixed once the root cause has been located. Here are the potential reasons:

a. Electromagnetic radiation – from computer, mobile phone, etc.
b. Stress – decreases blood supply to the brain, which results in memory loss.
c. Lack of sleep.
d. Diet – for instance: lack of vitamin B12 can cause brain fog.
e. Chemicals, pollutants, toxins, and insecticides.
f. Medication – such as cancer treatment (chemo brain).
g. Medical condition – alzheimer’s disease, hypothyroidism, autoimmune diseases, like lupus, arthritis, and multiple sclerosis, dehydration, etc.

How is Brain Fog Diagnosed

A doctor cannot identify brain fog with a single test. A doctor will conduct a physical examination and inquire about your health history, current medications or nutritional supplements, level of physical activity, diet, and mental health.

If you have other symptoms, for instance hair loss, dry skin, brittle nails, or weight gain, you should tell your doctor.

Moreover, your doctor may also conduct other tests like a blood test, imaging tests (X-rays, magnetic resonance imaging (MRI), or computerized tomography (CT) scans), and allergy testing.

Best Supplements to Fix Brain Fog

A. Vitamin B12
B. Vitamin D
C. Omega-3s
D. Magnesium
E. Vitamin C
F. L-theanine

A. Vitamin B12

Vitamin B12 has been shown to be associated with cognitive function. A vitamin B12 deficiency can result in behavioral abnormalities, dementia, memory issues, paranoia, depression, and other conditions.

A study of 202 people with cognitive impairment and low B12 levels discovered that B12 supplemental therapy enhanced cognition in 84% of participants and resulted in improved memory and attention tests in 78% of participants.

Additionally, older people are more common to get vitamin B12 deficiencies because it is absorbed from food by stomach acid. But as you get older, your stomach acid production tends to decrease. That’s why most older people are advised to take supplements.

1. MaryRuth Organics Vitamin B12 Liquid Spray

MaryRuth Organics Vitamin B12 Liquid Spray

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– Multiple Benefits
Maintain your body’s energy levels and benefit your brain by supporting neurofunction with this tasty berry spray. B12 may help the body with normal nerve function and red blood cells, but you also may notice increased energy if you’re deficient! Additionally, if you have an MTHFR gene variant (and around 40% of us might), you may find this to be your preferred type of B12!

– Vegan Formula
USDA Organic Methyl B12 Liquid Spray by MaryRuth’s Ingredients Per Serving (2 Sprays): 1500 mcg Vitamin B12 (as Methylcobalamin). Other Ingredients: Purified Water, Organic Glycerin, Organic Mixed Berry Flavor. Keep out of Children’s reach in case of accidental overdose or choking. Store in a cool, dry place.

– Easy-to-Take Liquid Drops
No more hard-to-swallow pills or capsules! Shake well before use. Adults take 2 sprays or as recommended by a physician or healthcare professional. Each bottle comes with 120 servings. Available in a One or Two-Pack!

– Free of Common Allergens
MaryRuth’s Methyl B12 Spray is USDA Organic, 100% Plant Based, Vegan, Non-GMO, Dairy Free, Nut Free, Gluten & Wheat Free, Soy Free, Corn Free, Nightshade Free, Sugar Free. Bariatric Friendly, Celiac Friendly, Keto Friendly.

4.6 out of 5 – more than 6,450 global ratings

MaryRuth Organics Vitamin B12 Liquid Spray Reviews
After reading Dr. Wentz books on Hashimoto thyroiditis
I started to use this supplement and noticed a lot of the Brain ‘fog’ i was having disappear. I am more focused and very happy with the ease in using this product and it has a great flavor.

2. SLS Vitamin B12 Liquid Spray

SLS Vitamin B12 Liquid Spray

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– Fast Absorption
Our Vitamin B12 Sublingual Fast-Acting Complex will not only be absorbed into your body faster, but it is also more soluble than capsules so that you will get more of the vitamin into your system as well.

– Suitable for Vegans and Vegetarians
Our Vitamin B12 is Vegan, Non-GMO, Gluten Free and does NOT contain any Yeast, Wheat, Milk or Milk Derivatives, Lactose, Sugar, Soy, Artificial Colors and Flavors. Each easy to open bottle contains 2 fluid ounces which is a full 60-day supply.

– Energy Boost
If you’ve been dragging a lot lately, it could be that you’re not getting enough Vitamin B12. Along with the other B Vitamins, B12 is known for its ability to convert carbohydrates into glucose which leads to energy production. The boost in energy levels will help keep you alert and feeling energized throughout the day.

– Speed Up Metabolism
Vitamin B-12 assists the digestive system to function properly and you will notice that if you don’t get enough of it you are more prone to constipation and a sluggish digestive system.

4.4 out of 5 – more than 5,450 global ratings

SLS Vitamin B12 Liquid Spray Reviews
Within a few days I could feel huge difference in my brain clearity. No more foggy brain or forgetfulness. Will continue to repurchase.

B. Vitamin D

Vitamin D is a potent antioxidant and anti-inflammatory in our brain. Low vitamin D levels can have a bad effect on cognitive health and contribute to brain fog symptoms.

A few research also revealed a link between depression and low vitamin D levels. Brain fog symptoms, such as difficulty concentrating and memory issues, are frequently experienced by people who have depression.

How Much Vitamin D Per Day Is Safe?

According to the U.S. National Academy of Medicine, the safe upper limit is 4,000 IU (100 mcg) per day (nih.gov).

Only 400 to 800 IU (15 to 20 mcg) of vitamin D is needed daily to maintain healthy levels, but higher dosages, such as 2,000 IU daily, are used to enhance low levels and are generally safe. However, without your doctor’s permission, don’t take more than 4,000 IU of vitamin D. It exceeds the safe upper consumption limits and isn’t related to any additional health advantages.

3. SmarterNutrition Plant-Based Vitamin D3 5000IU with Vitamin K2

SmarterNutrition Plant-Based Vitamin D3 5000IU with Vitamin K2

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– Remium Plant-based Vitamin D3
Unlike other Vitamin D supplements that contain lanolin excreted from sheep’s glands, then chemically processed, Smarter Nutrition’s Vitamin D3 comes from the most premium plant source of active Vitamin D3.

– 4 Natural Ingredients
Smarter Nutrition Vitamin D3 is encapsulated in vegetarian softgels with organic extra virgin coconut oil for faster bioavailability than powdered products. The medium chain triglycerides (MCTs) in coconut oil provide quick energy for the body and enable absorption of the fat-soluble vitamins D3 and K2.* It’s the optimal blend of ingredients for safety and maximum benefits.

– Fully Bioavailable Vegetable Softgels
Using cutting-edge technology, Smarter Nutrition Vitamin D3 is encapsulated in vegetarian softgels without chemical coatings, fillers, and synthetic binders.

– Includes Vitamin K2
Smarter Vitamin D3 includes vitamin K2 to support bone health.* Vitamin D3 pulls calcium into the bloodstream, but it’s actually vitamin K2 that pushes calcium from your blood and into your bones.

– 5,000 IU of Vitamin D3
Vitamin D supports a healthy immune system, as well as various other processes and systems throughout the body. It is an essential nutrient for overall health and wellness.

4.8 out of 5 – more than 2,800 global ratings

SmarterNutrition Plant-Based Vitamin D3 with Vitamin K2 Reviews
Smarter Nutrition’s plant-based Vitamin D3 supplement is easy to swallow and leaves no aftertaste. I value its ability to support brain health by helping to alleviate “brain-fog” and positively elevate my mood. Additionally, the added value of immune system support makes this supplement a win-win.

4. Doctor's Best Vegan Vitamin D3 2500IU

Doctor's Best Vegan Vitamin D3 Supplements

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– Doctor’s Best Vegan D3 Features Vitashine D3
A plant source of vitamin D3 (cholecalciferol), the superior form of supplemental vitamin D. Needed for the body to regulate phosphorus and calcium levels for bones, teeth and heart protection. Vitamin D3 is produced in the skin by absorbing the sun’s UV rays and is obtained from food in limited amounts. Sun protection and climate factors may influence low Vitamin D3 levels.

– Vitamin D Benefits
Vitamin D is essential to ensure healthy control over calcium absorption and the availability of calcium to bone. Multiple studies have shown its support for healthy bone structure from childhood through old age. The liver converts cholecalciferol into the activated form of vitamin D (25-hydroxy vitamin D3) and not only influences bone health but helps support immune system responses, the heart and circulation, the lungs, the musculoskeletal system and virtually all the body’s other functional systems.

4.8 out of 5 – more than 3,350 global ratings

Doctor’s Best Vegan Vitamin D3 2500IU Reviews
good price and suits my needs for gluten free and a whole food plant based diet to supply needed fats for my elderly brain!

5. MaryRuth Organics Liquid Vitamin D Spray

MaryRuth Organics Liquid Vitamin D Spray

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– Vegan Vitamin D3 Oral Spray
Unflavored. Non-GMO, Vegan, All Natural and Organic Ingredients! For Men, Women and Children. Did you know that 99% of Vitamin D3 comes from Lanolin (Sheep’s wool)? MaryRuth’s Vegan Vitamin D3 comes from Non-GMO Vegan Lichen.

– GMP Compliant
Made in GMP compliant facility in a 1oz glass bottle. Mother-daughter owned company. Made in USA!

Always review our ingredients (below) and the Supplement Facts chart carefully to ensure you do not have any sensitivities. Children under 12, seniors over 65, and pregnant or lactating women should always consult with a physician or healthcare professional prior to use. If you have any questions, please reach out to us.

4.7 out of 5 – more than 1,200 global ratings

MaryRuth Organics Liquid Vitamin D Spray Reviews
I purchased this product because, as someone with endometriosis, I frequently have a vitamin D deficiency. I like the fact that this organic product is in liquid form. Sometimes capsule or pill forms irritate my stomach. There is virtually no taste to this product, so the product is very tolerable to take. I recommend this product.

C. Omega-3s

Omega-3 fatty acids are known for having remarkable health benefits. Concentrated omega-3 supplements may improve some signs of brain fog, such as problems paying attention and remembering things.

Omega-3 fatty acids (EPA and DHA) supplementation have been shown in studies to enhance brain health, including memory, attention, and mood. A study with 176 adults who consumed little omega-3 discovered that supplementing with 1.16 grams of DHA per day for six months improved episodic and working memory more than a placebo.

6. Bronson Omega 3 Fish Oil Triple Strength 2720 mg

Bronson Omega 3 Fish Oil Triple Strength 2720 mg

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– Extra High-Potency
2720 MG of Fish Oil , 1250 MG EPA and 488 MG DHA per serving.

– Promotes Heart Health
Omega-3 fatty acids have been shown to help promote heart and joint health, may also help support a positive mood, healthy brain function, and eye health.*

– Safe & Effective
Non-GMO, Gluten-Free, Soy-Free and Heavy Metal tested. Perfect for people of all ages.

– Highest Quality Formula
We use only the best ingredients available. Manufactured in a FDA Registered cGMP Facility. Laboratory tested.

4.6 out of 5 – more than 1,050 global ratings

Bronson Omega 3 Fish Oil Supplement Reviews
This has the most EPA and DHA per serving for the money. Generally Fish Oil is Fish Oil is Fish Oil. But best value per pill, this is it. No fishy taste, no burps, great product. I intend to use this for the rest of my Fish Oil supplementation.

7. Garden of Life Omega 3 Fish Oil Supplement with Vitamin D

Garden of Life Omega 3 Fish Oil Supplement with Vitamin D

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Minami Platinum Omega-3 Fish Oil is an ultra-concentrated omega-3 supplement made from the purest fish oil utilizing dual supercritical CO2 extraction technology that delivers an unprecedented 1,100mg of omega-3s in the natural triglyceride form, in just one softgel daily. It has a clean orange flavor with no fishy aftertaste, and with 1,000IU of added vitamin D, this unique omega-3 supplement is designed to support brain, mood, immune and cardiovascular health.†

– concentrated omega-3 fish oil plus vitamin d3
– 1,100mg total of omega-3 nutrition in just one softgel daily
– 1,000iu vitamin d3, 250% daily value
– clean, orange flavor and no fishy aftertaste

4.7 out of 5 – more than 1,850 global ratings

Garden of Life Omega 3 Fish Oil Supplement with Vitamin D Reviews
Overall, in terms of physical attributes, these capsules are quite large but very easy to swallow since they have a smooth surface. Also they have a slight orange taste and leaves no after taste. There are also no fish burps. I like the ratio of EPA to DHA, which most experts agree is desirable. The bottle is protective of light which is important to preserve the capsule. The price of this product is higher than most, however in my opinion well worth it.

D. Magnesium

Magnesium is a mineral that plays a role in a number of vital biological functions. Magnesium may help you sleep better. It aids in the activation of mechanisms that quiet and relax you, and it plays a key part in your nervous system. It may also aid in the relief of anxiety and depression, both of which can cause brain fog.

In a study of older adults aged 60 and older, it was discovered that those with higher magnesium levels performed better on tests of cognitive abilities including attention and memory and had lower risks of developing cognitive impairment.

Some animal studies have found that magnesium threonate is more effective at increasing magnesium ions in the brain and improving cognitive function than magnesium sulfate. Therefore, doctors may recommend magnesium L-threonate to normalize an individual’s magnesium levels and for potential benefits to the brain. (Source)

8. Life Extension Neuro-Mag Magnesium L-Threonate

Life Extension Neuro-Mag Magnesium L-Threonate

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Best Magnesium Supplement for Brain Health

– Magnesium L-threonate Helps Your Brain Work Better
Your daily activities demand focus and attention. Still, over time, the little details can slip your mind and you find yourself looking for sunglasses that are on your head. That’s where our formula comes in! Our magnesium L-threonate is easy for your body to absorb into the nervous system and your brain, where it helps maintain the crucial connections between your brain cells.

– Maintain Ideal Magnesium Levels
Magnesium does wonders for your brain, but it’s also important to more than 300 biochemical reactions in your body. Unfortunately, most of us don’t get enough magnesium from our diets, and optimal levels begin to decline as we age. That’s why supplementing with (easy-to-absorb) magnesium is a great complement to your healthy lifestyle choices, especially over time!

– Ingredients Matter
Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every product we produce.

4.6 out of 5 – more than 6,550 global ratings

Life Extension Neuro-Mag Magnesium Supplement for Brain Fog Reviews
Morning of Day 4 the brain fog is gone. After 3 years of the cloud living in my consciousness slowly putting me to sleep, I have taken initiative and made the effort to stop the numbing effects of whatever it is that is slowing me down and not caring. THIS is Working and working fast. 

I am not a paid or bribed in any way to write a review. I want to raise my hand for all of those who seek a genuine review in a sea of unilateral bribe contracts across google. So far, this is a true product. I will write again for I predict my functioning may get better with continued use. Awesome I recommend Neuro-mag

9. Designs for Health NeuroMag - Chelated Magnesium L-Threonate for Cognitive Support

Designs for Health NeuroMag - Chelated Magnesium L-Threonate for Cognitive Support

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Best Magnesium Supplement for Cognitive Function

– Cognitive Focused Magnesium
Researchers at MIT concluded that elevating brain magnesium content via supplementation with magnesium L-threonate may be a useful strategy to support cognitive abilities.* 

– Superior Bioavailability
Many Magnesium supplements have low bioavailability in relation to the brain. This form of magnesium may offer superior brain support due to its ability to transport magnesium ions across lipid membranes.*

– Promote Clarity
Magnesium chelated to threonic acid may support memory, clarity, and the brain health in already healthy individuals.*

– Higher Standards, Better Results
Designs for Health maintains a strict, no-compromises approach to quality raw material selection. We never cut corners with substandard ingredients. This product is Non-GMO, Gluten-Free, and Vegetarian-friendly.

4.8 out of 5 – more than 200 global ratings

Designs for Health NeuroMag Magnesium L-Threonate Reviews
This type of magnesium crosses the blood brain barrier as explained by our doctor. Great for autistic children and overall brain health!!

E. Vitamin C

According to a study, having appropriate vitamin C levels in the blood was linked to better focus, memory, concentration, and attention. Brain fog may result from low vitamin C levels, which may also lead to symptoms like depression.

A study suggests that vitamin C may produce mood-elevating effects in patients with subclinical depression. This might improve cognitive function, so lessening depression-related brain fog.

10. Ester-C Vitamin C 500mg | 24 Hour Immune Support*

Ester-C Vitamin C 500mg | 24 Hour Immune Support*

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Ester-c 24 hour vitamin c supplement tablets for immune support offer a unique formula that stays in your system for up to 24 hours, so you have around-the-clock immune support. The metabolites in ester-c help enhance the retention of vitamin c in your white blood cells, which are a vital component of your immune system.

– this vitamin c supplement is clinically studied to last up to two times longer than regular vitamin c
– non-gmo, gluten free vegetarian vitamins are made with no artificial color, flavor, or sweetener

For adults, take two ester-c 500 mg vitamin c immune support supplements once daily, preferably with a meal.

4.8 out of 5 – more than 6,200 global ratings

Ester-c Vitamin C Immune Support Tablets Reviews
I prefer this type of Vit C as it does not bother my stomach as much as the cheaper kind. I take one a day as maintenance, but when coming down with a bug I take 2-3 a day. I do not get sick as often or as bad when taking this product.


a. Does Brain Fog Affect Memory?

Yes, someone who has brain fog may feel as though their thinking, understanding, and memory functions are not functioning properly. Their memory, particularly their capacity to store and recall information, may be affected.

b. Does Covid Cause Brain Fog?

Brain fog after COVID-19 is biologically similar to cognitive impairment caused by cancer chemotherapy, something doctors often refer to as “chemo brain.” In both cases, excessive inflammation damages the same brain cells and processes, according to research led by Stanford University School of Medicine.

We found that even mild COVID can cause prominent inflammation in the brain that dysregulates brain cells and would be expected to contribute to cognitive impairment,” said Michelle Monje, MD, PhD, professor of neurology and neurological sciences. (Source)

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