The Medical Advisor

In the video below (1), board-certified dermatologist Dr. Andrea Suarez, known online as Dr. Dray, shares some fascinating insights about niacinamide, a water-soluble form of vitamin B3 (niacin), and its benefits for skin health. Niacinamide, also known as nicotinamide, is a precursor for NAD+, which is not only involved in the conversion of food to energy but is also important in the process of repairing damaged DNA. This is crucial because your skin faces constant environmental stressors, including ultraviolet (UV) radiation, which can damage DNA in skin cells and suppress your immune system. Niacinamide shows promise for skin cancer prevention due to its ability to enhance DNA repair and reduce UV-induced immunosuppression in skin cells. These mechanisms are useful in preventing the development of non-melanoma skin cancers (NMSCs), which include basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The Promise of Niacinamide for Skin Cancer Prevention Clinical trials ...

  Niacinamide is a precursor to NAD+ (nicotinamide adenine dinucleotide), a vital signaling molecule that’s believed to play an important role in longevity. In fact, the best single NAD+ precursor is niacinamide, and this is reason alone to educate yourself about its benefits, but niacinamide, also known as nicotinamide (NAM), is also valuable in its own right. Supplementation with NAM has been found to improve insulin sensitivity in models of human diabetes, for instance, and it also decreases oxidative stress and prevents fatty liver. 1  It also shows impressive promise for fighting obesity and associated diseases, including stroke, cardiovascular diseases, diabetes and certain cancers, which have reached epidemic levels worldwide. 2 But the key with NAM is that you need the right “Goldilocks” dose. The most common mistake people make is taking too much and thereby actually sabotaging any metabolic benefits. Niacinamide Reprograms Fat Metabolism, Ameliorates Obesity NAD+ mod...

Dr. David Minkoff is a pioneer in natural medicine with an active practice in Clearwater, Florida. In this interview, we dive deep into some of his best strategies to optimize your health and resolve common health challenges that conventional medicine is incapable of resolving. Like me, he’s passionate about exercise and has been an avid athlete since his youth. So far, he’s participated in 43 Ironman competitions and will be doing another in September 2022.  “Most of my practice is chronically ill people, but I have worked with some very high-end athletes, and I can really help them because I understand what kind of metabolism you need to do to be able to perform consistently at a high level,” he says. “I've sort of been in the laboratory myself, and that's been very helpful.”   Dr David Minkoff’s Journey  Minkoff has had a rather eclectic medical training, including adult and pediatric infectious disease. In 1995, his wife, a registered nurse, took him to a series of J...

About 21% of U.S. adults suffer from chronic pain, with new cases occurring more often than new cases of other common conditions like diabetes, depression and high blood pressure (1). Pain is considered chronic if it occurs every day or most days over a period of three months or more. For about 8%, the chronic pain is considered high-impact, 2  meaning it limits life or work activities, demonstrating the heavy burden this condition places on those affected. Many reach for dangerous opioid drugs for relief, which suppress mitochondria 3  — the last thing you want if you’re struggling with chronic pain. Chronic Pain Is a Symptom of Mitochondrial Dysfunction Researchers with Utrecht University in the Netherlands revealed that nicotinamide riboside (NR) — a form of vitamin B3 and precursor to nicotinamide adenine dinucleotide (NAD+), a molecule involved in DNA repair and healthy aging — helps relieve chronic pain in mice 4  by improving mitochondrial function. “Previous resea...