The Medical Advisor

The pharmaceutical market in 2025 continues to be led by innovative therapies addressing cancer, metabolic diseases, autoimmune conditions, and chronic illnesses. Below is an updated overview of the top 10 drugs by projected global sales in 2025. 1. Keytruda (Merck) 2. Ozempic (Novo Nordisk) 3. Mounjaro (ELi Lilly) 4. Dupixent (Sanofi and Regeneron) 5. Wegovy (Novo Nordisk) 6. Biktarvy (Gilead Sciences) 7. Skyrizi (Abbvie) 8. Eliquis (Bristol-Myers Squibb) 9. Darzalex (Johnson & Johnson) 10. Humira (Abbvie) Among the top ten best-selling drugs forecasted, three belong to the GLP-1 class, all of which fall under metabolic therapy. Additionally, two autoimmune drugs, Dupixent (dupilumab) and Skyrizi (risankizumab), remain regulars on the best-seller list, ranking fourth and seventh, respectively. Keytruda (Pembrolizumab) remains the global leader in drug sales with projected revenues exceeding $31 billion in 2025. This cancer immunotherapy has expanded to over 40 approved indication...

Patients with lupus have an imbalance in a crucial chemical pathway in their bodies, according to a Nature study published on Wednesday. Researchers found  (Nature) that this imbalance produces more disease-causing cells that promote lupus. If this chemical imbalance can be corrected, they believe lupus can be reversed. Current lupus treatments often target symptoms or broadly suppress the immune system, leading to side effects. The researchers believe targeting the specific chemical imbalance identified could more effectively treat lupus without systemic immunosuppression interventions. Lupus is a chronic autoimmune disease that causes the body to attack its own tissues and organs, including the joints, skin, kidneys, blood cells, brain, heart, and lungs. There is currently no cure for lupus. A Surprising ‘Molecular Switch’ The chemical that researchers identified is the aryl hydrocarbon receptor (AHR). AHR is a key protein involved in the imbalance of immune cells in lupus patien...

Exercise really is as good as a drug, a groundbreaking new study found. In a global trial, workouts did better than pricey chemotherapy to prevent colon cancer recurrence. Oncologists gathered at the biggest annual cancer meeting in June gave the news a standing ovation. For over a decade, the medical community has recognized that exercise may improve cancer outcomes. One of the earliest clinical indications came from the Nurses’ Health Study in 2006, which showed that substantial and sustained weight loss over several years was associated with a lower incidence of postmenopausal breast cancer ( JAMA 2006 ). In the years since, numerous preclinical and observational studies have supported the idea that physical activity can positively influence cancer outcomes. However, definitive level 1 evidence has remained elusive. Scientists and doctors often joke that exercise is one of the best drugs we have. But can a workout truly rival chemotherapy in...

In This Article: Methodology: Focuses on evidence-based research for cancer prevention and supplements. What is Cancer & Causes: Discusses how lifestyle and environmental factors contribute to cancer risk. Diet & Cancer Prevention: Plant-based, Mediterranean diets; avoid processed foods and red meat, sugar, and alcohol. Lifestyle & Cancer Prevention: Quit smoking, maintain healthy weight, exercise, reduce stress, and avoid radiation. Best Anti-Cancer Supplements: Includes Vitamin D3, Turmeric, Omega-3, Vitamin C, Green Tea Extract (EGCG), Magnesium, Molecular Hydrogen, Zinc, Probiotics and Garlic. Other Recommendations: Quality sleep, regular medical care, avoiding toxins, infections, carcinogens. Key Takeaways: Focus on holistic health, proper diet, supplements, and lifestyle changes. Introduction Despite trillions spent on cancer research , cancer still  kills around 10 million people a year  and is a leading cause of death globally, according to the W...