Ivermectin and Fenbendazole for Psoriasis: 12 Case Reports (2025)

More than a superficial skin condition, psoriasis is a chronic condition of your immune system that triggers cells to build up on the surface of your skin. This leads to thick, scaly and red patches that itch and are sometimes painful.

Approximately 7.5 million Americans suffer with psoriasis, which also has a surprising economic impact. (1)

The combined annual cost of psoriasis reached nearly $112 billion in 2013 (2). Although it commonly affects the skin, it also affects your joints (psoriatic arthritis), and has been associated with diabetes, asthma, cardiovascular disease and depression. (1)

Psoriasis also has significant emotional and mental impact on patients, with the prevalence of depression measured as high as 50%. (1)

While psoriasis is an inflammatory response, it can lead to an infection if you frequently scratch the affected areas. 

Ivermectin and Fenbendazole for Psoriasis

Ivermectin and Fenbendazole combination works surprisingly well in psoriasis.

Case No. 12

@SDSmith51562954 shared on X in June 2025:

I’ve had psoriasis for 30yrs (depressing), got severe in last 5yrs, took IVM (6mg) 2x daily for 20 day (bought in Mexico) to test & severity reduced. Went to doc (Alberta) to show results & could not get IVM. Doc needs to do research first . Tried all, IVM works & cant get it.

Case No. 11

@susieqjax75 shared on X in June 2025:

Got my 15 YO nephew taking it for his severe psoriasis. He started it three weeks ago when he came to visit me here in Florida. He has about 80 to 90% coverage on his body. After three weeks of alternating between topical and oral (ivermectin), he is almost completely clear . His mother and father are beside himself and it’s been fun to watch his self-confidence grow.

Case No. 10

Thefirmament17 shared on X (Twitter) in March 2025:

 "Yes ivermectin and febendazole works! Treated my psoriasis within 30 days skin cleared up. Had the problem for 15 plus years. "

Case No. 1 - 9

Dr. William Makis shared on X (Twitter) in March 2025:

Case 1: 15 years of Psoriasis "Thank you Dr.Makis. Yes Ivermectin and fenbendazole works! Treated my psoriasis within 3 days skin cleared up. Had the problem for 15 plus years." 

Case 2: Stage 1 Breast Cancer Patient: "On a positive note, my mother has noticed that her psoriasis has started to clear up for the first time in years since she began taking IVM." 

Case 3: Stage 4 Lung Cancer Patient: "I found that my scalp psoriasis cleared up after taking your oral protocol within a couple of weeks" 

Case 4: "I've been taking Ivermectin for almost a month. A tooth I thought would need a root canal doesn't. Psoriasis is gone. Clear skin. Stomach pain on left side. Gone." 

Case 5: "37 years of psoriasis spent thousands on treatments steroids have damaged me and a few weeks ago I took fenbendazole like Ivermectin and 4 weeks later I'm 95% clear" 

Case 6: "I solved a bad case of psoriasis with Ivermectin & Fenbendazole" 

Case 7: "Update on Ivermectin for psoriasis, used 4 days topically. My inflammation has gone down, not itchy, and huge visible difference." 

Case 8: "I have psoriatic arthritis, and I noticed that my mild psoriasis cleared up after the course of Ivermectin too!" 

Case 9: "girl in office told me last year they rx for Ivermectin for Psoriasis & she was in a clinical trial for it years ago" 

Ivermectin is fantastic for many inflammatory and auto-immune conditions, including FDA approved for Rosacea!

Buying Guide: 1.87% ivermectin paste is affectionately known as "horse paste" (Buy on Amazon)

Related: Ivermectin, Fenbendazole, Vitamin D, Curcumin and Omega-3 for Psoriasis Treatment

Sources and References

1 American Academy of Dermatology, Psoriasis (Archived)
2 Journal of the American Medical Association, 2015;151(6):651