Global Campaign for Vitamin C and COVID-19: VitaminC4COVID

By Dr. Frank Yap, MD -

VitaminC4COVID.com - The VitaminC4COVID campaign is backed by leading vitamin C scientists, doctors and nutritionists with more than 5000 signatories from about 60 countries.

SOMMAI/ Shutterstock

The UK-led campaign cites a review of more than 100 vitamin C trials, published recently in Nutrients. Lead author of the review, Patrick Holford, told Nutraingredients vitamin C data was as strong as that which existed for vitamin D and had the potential to reduce COVDI-19 symptoms at low cost and 'suppress viral replication in the early stages'.

A randomised controlled trial in Wuhan, China showed 68% less death among critical COVID-19 ICU patients on a ventilator with high dose vitamin C. A Spanish trial showed 17 out of 18 ICU patients had undetectable vitamin C levels.

"The irony is that Zhongnan Hospital ran out of COVID patients by the end of April as a consequnce of the Chinese government shipping in 50 tons (50 million 1g doses) into Wuhan on February 2nd and distributing to all hospitals which not only gave hospitalised patients high doses of vitamin C, intravenously in ICUs, but also gave daily vitamin C to all hospital workers," Holford said.

The current WHO (World Health Organisation) position of supplementation states: "Micronutrients, such as Vitamins D and C and Zinc, are critical for a well functioning immune system and play a vital role in promoting health and nutritional well-being."

According to Holford, "We've had 11 viral epidemics this century. The reality is there will be more. Keeping one's immune system strong with vitamin D, vitamin C and Zinc is a critical part of any anti-viral strategy."

The Science

Patrick Holford 1,* Anitra C. Carr 2, Thomas H Jovic 3 4, Stephen R Ali 3 4, Iain S Whitaker 3 4, Paul E Marik 5, A. David Smith 6

1 Founder of the Institute for Optimum Nutrition, Ambassador House, Paradise Road, TW9 1SQ Richmond, UK; pat@patrickholford.com
2 Nutrition in Medicine Research Group, Department of Pathology & Biomedical Science, University of Otago, Christchurch, P.O. Box 4345, Christchurch 8140, New Zealand. anitra.carr@otago.ac.nz
3 Reconstructive Surgery & Regenerative Medicine Research Group, Institute of Life Sciences, Swansea University Medical School, Swansea University, SA28PY Swansea, UK; Thomas.Jovic@wales.nhs.uk
(T.H.J.); Stephen.Ali@wales.nhs.uk (S.R.A.); Iain.Whitaker@wales.nhs.uk (I.S.W.)
4 Welsh Centre for Burns & Plastic Surgery, Morriston Hospital, SA66NL Swansea, UK
5 Division of Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA. marikpe@evms.edu
6 Department of Pharmacology, University of Oxford, Oxford OX1 3QT, UK. david.smith@pharm.ox.ac.uk.

Abstract: There are limited proven therapies for the treatment of COVID-19. Vitamin C’s antioxidant, anti-inflammatory and immunomodulating effects, make it a potential therapeutic candidate, both for the prevention and amelioration of COVID-19 infection, and as an adjunctive therapy in the critical care of COVID-19, supporting anti-inflammatory treatment.

This literature review focuses on vitamin C deficiency in respiratory infections including COVID-19; the mechanism of action in infectious disease and adrenal function supporting the anti-inflammatory actions of glucocorticosteroids: its role in preventing and treating colds and pneumonia and its role in treating sepsis and COVID-19.

The evidence to date indicates that oral vitamin C (2-8g/d) may reduce incidence and duration of respiratory infections and intravenous vitamin C (2-24g/d) has been shown to reduce mortality, Intensive Care Unit and hospital stays, time on mechanical ventilation in severe respiratory infections. Further trials are urgently warranted.

Given the favourable safety profile and low cost of vitamin C, and frequency of vitamin C deficiency in respiratory infections it may be worthwhile testing patients’ vitamin C status and treating accordingly with intravenous use within ICUs and orally with doses between 2 and 8g/day in hospitalised and infected persons.




Comments

Post a Comment

Labels

Show more

Popular posts from this blog

12 Types of Zinc Supplementation and Absorption 2024

By Dr. Frank Yap, MD -
Image
Zinc is a powerful immune nutrient known for its benefits for providing immune health support and anti inflammation as well as for improving cold and respiratory symptoms, wound healing, acne reduction, and lowering the risk of age-related diseases. Research on atherosclerosis and diabetes mellitus suggests that zinc deficiency may contribute to low-grade systemic inflammation. Types of Zinc What's the best absorbed zinc supplement form?  We know there’s an ocean of information out there to navigate, so we’ve compiled a list of common zinc types and an overview on each zinc type below. There are several types of zinc supplements. Supplements contain several forms of zinc, including zinc gluconate, zinc citrate and zinc picolinate. The percentage of elemental zinc varies by form.  Choosing a zinc supplement can be confusing because there are so many different types. zinc acetate zinc angstro
Read more

Fenbendazole vs Mebendazole: What is the Difference?

By Dr. Frank Yap, MD -
Image
Fenbendazole for Humans Fenbendazole (also known as fenben) is a veterinary medication used to treat parasites and worms such as tapeworms, hookworms, roundworms, and whipworms, in animals. It is commonly used under brand names like Panacur C and Safe-Guard. Recently, researchers have been experimenting with fenbendazole for humans cancer. Though the studies are limited, what researchers have found so far is promising for cancer patients. Many cancer patients have been following the Fenbendazole for cancer Protocol . However, fenbendazole isn’t the only worming medication that has the potential to fight cancer. Researchers have also been studying how Mebendazole, a drug that can treat worms in humans, could be just as, or even more, effective at shrinking tumors and killing cancer cells. Here’s what you need to know about each of these medications: Fenbendazole vs. Mebendazole Fenbendazole is part of a larger group of drugs known as benzimidazole, which are anthelmintic dr
Read more

Fenbendazole Cancer Success Stories and Treatment Testimonials: Case Series (2024)

By Dr. Frank Yap, MD -
Image
The inspiring testimonials (below) you are about to read are shared by individuals who have generously recounted their remarkable journeys with the hope of motivating and uplifting fellow patients. It’s essential to acknowledge that while these case studies offer incredible hope, the Fenbendazole protocol isn’t a universal solution. Related:  Best Anti Cancer Supplements Below is the list categorised by different cancer types alphabetically. Fenbendazole Breast Cancer Success Stories December, 2022 Condition: Stage 4 ER+PR+HER2- Metastatic Breast Cancer to bones A friend told me about the Joe Tippens Protocol and ivermectin the day after I got my diagnosis for a third bout with breast cancer. I started both immediately. I saw my oncologist a week later. She added Faslodex, Kisqali, and Femara. She supported me added the JTP and the ivermectin. In 8 weeks I was in remission as measured by my CA2729. At week 11, a PET scan showed NED. Which of the protocol components
Read more

Lumbrokinase vs Nattokinase vs Serrapeptase: What's the Difference?

By -
Image
Lumbrokinase, nattokinase, and serrapeptase are all enzymes that have been studied for their potential health benefits. They are all considered as proteolytic enzymes. Proteolytic enzymes have a variety of roles in the body, from helping to digest food to taking part in the immune response. What is Lumbrokinase? Lumbrokinase (LK) is an enzyme derived from earthworms is thought to aid in blood clot prevention, inflammation reduction, and circulation problems.  Lumbrokinase for Blood Clots Thrombolytic agents typically used to dissolve clots are urokinase (u-PA), streptokinase, and tissue plasminogen activator (t-PA). These drugs, however, are not specific for fibrin and have adverse and dangerous side effects including severe bleeding and heavy blood loss which may result in death. In contrast, LK is very specific to fibrin as a substrate and it does not cause excessive bleeding. It can dissolve the fibrin itself or convert plasminogen to plasmin by inducing endogenous t-PA activity to
Read more

How to Detox Spike Protein After COVID - Dr Mercola

By Dr. Frank Yap, MD -
Image
The spike protein is naturally found in SARS-CoV-2, no matter the variant. In its native form in SARS-CoV-2, the spike protein is responsible for the pathologies of the viral infection. As of October 30, 2023, federal  data  published by the US CDC found that 14.3% (National Estimate) of adults who previously had a COVID-19 infection are currently experiencing symptoms of long COVID.  In its wild form it’s known to open the blood-brain barrier, cause cell damage (cytotoxicity) and, as Dr. Robert Malone, the inventor of the  mRNA and DNA vaccine core platform technology , said in a commentary on  News Voice , “is active in manipulating the biology of the cells that coat the inside of your blood vessels — vascular endothelial cells, in part through its interaction with ACE2, which controls contraction in the blood vessels, blood pressure and other things.” It’s also been revealed that the spike protein on its own is enough to cause inflammation and damage to the vascular system, even i
Read more

NAC vs NAD vs NR vs NMN? What are the Differences?

By Dr. Frank Yap, MD -
Image
NAC vs NAD vs NR vs NMN ? Due to the small alphabetical differences, these supplements are often mixed up and confused by most consumers. We will cover the essentials and explain about each of these supplements below. NAD NAD is derived from Nicotinamide Riboside (NR). The levels of NAD in our body determine the speed of aging process. In younger cells and tissues, the levels of NAD are higher. As a result, younger people tend to have better physical activity, cognitive function and potential for cell repair and regeneration. As we grow, the levels of NAD in our body start to decline. This is reflected in the form of slowed cognitive response, loss of memory and reduced agility. Research suggests it may be possible to reverse mitochondrial decay with dietary supplements that increase cellular levels of a molecule called NAD (nicotinamide adenine dinucleotide).  NAD is a linchpin of energy metabolism, among other roles, and its diminishing level with age has been implicated in mitochond
Read more

How Linoleic Acid Wrecks Your Health (2024) - Dr Mercola

By Dr. Frank Yap, MD -
Image
The majority of Americans might be misled by official health recommendations to eat “healthy” vegetable oils. Even the term “vegetable oil” is misleading because it gives you the impression that you are receiving vegetable micronutrients when these oils are actually highly toxic, industrially-processed seed oils. Seed oils are some of the most dangerous items you could eat. Tucker Goodrich and Dr Mercola discussed what will be the topic of Dr Mercola's next book, namely linoleic acid (LA), which he believed is likely the leading contributing cause of virtually all chronic diseases we've encountered over the last century. Unfortunately, this is a topic that most clinicians and health care practitioners who focus on natural medicine have only a superficial understanding of.   Goodrich has a business background as a stockbroker and asset manager, and developed an IT risk management system used by two of the largest hedge funds in the w
Read more

FLCCC I-MASK+ Protocol for COVID-19

By Dr. Frank Yap, MD -
Image
FLCCC (Front Line COVID-19 Critical Care) I-MASK+ Protocol I-MASK+ Prevention & Early Outpatient Treatment Protocol for COVID-19 was designed for use as a prevention and in early outpatient treatment, for those who test positive for COVID-19. Component nutrients include vitamin D, C, melatonin, quercetin and zinc . All the component medicines are FDA-approved (except ivermectin), inexpensive, readily available and have been used for decades with well-established safety profiles. Please take note that I-MASK+ protocols are now: I-PREVENT protocol for prevention (prophylaxis) I-CARE protocol for early treatment . PREVENTION PROTOCOL As rates of infection with influenza and RSV rose in fall/winter 2022, FLCCC adapted th
Read more

The Key to Reversing All Autoimmune Diseases - Dr Mercola

By Dr. Frank Yap, MD -
Image
It has been estimated that over 54.4 million people in the United States have an autoimmune disease  ( R ).   Some of the major ones would be rheumatoid arthritis (RA), multiple sclerosis and inflammatory bowel diseases like Crohn's and ulcerative colitis. Since I have a massive clinical experience with RA (Rheumatoid Arthritis), I am going to use it as an example of how all autoimmune diseases can be treated. Why? Because they all have similar origins which are related to an antigen sneaking into your body and your immune system confusing it as a foreign invader. The antigen that gets into your system determines which of your body's tissues will be impacted. From the late 1980s and for the following 10 years, I treated over 3,000 patients with rheumatic illnesses, including systemic lupus erythematosus (SLE), scleroderma, polymyositis and dermatomyositis. RA has a devastating prognosis in many patients. Rheumatoid arthritis affects about 1% of our population
Read more

How to Get Ivermectin in the US: Pharmacies (2023)

By Dr. Frank Yap, MD -
Image
To assist all who are having difficulty finding pharmacists to fill prescriptions for ivermectin for preventing or treating COVID-19, FLCCC offer the following list of pharmacies that have assured us that they will fill these off-label prescriptions. Note: Ivermectin is often recognized – 2nd to penicillin – for having the greatest impact on human health. And its discovery won the Nobel Prize in 2015. Ivermectin has an increasing list of indications due to its antiviral and anti-inflammatory properties, and is included on the  WHO’s Model List of Essential Medicines .  Several studies reported antiviral effects of ivermectin on RNA viruses such as Zika, dengue, yellow fever, West Nile, Hendra, Newcastle, Venezuelan equine encephalitis, chikungunya, Semliki Forest, Sindbis, Avian influenza A, Porcine Reproductive and Respiratory Syndrome, Human immunodeficiency virus type 1, and COVID 19 virus. Ivermectin also offer potential benefits in addressing conditions such as  cance
Read more