The Medical Advisor

When it comes to health and disease prevention, your mitochondrial health and function simply cannot be overstated. If your mitochondria are not functioning well, nothing else will either. Optimization of mitochondria is also a central key for life extension. Dr. Lee Know, who is a naturopathic physician, has written a must-read book on this topic called " Mitochondria and the Future of Medicine: The Key to Understanding Disease, Chronic Illness, Aging, and Life Itself ." Lee Know has been a passionate student of mitochondria for quite some time. "I've always been interested in antiaging and longevity, but that was not the motivation behind the book," he says. That motivation grew out of an interest in Coenzyme Q10. Animal research was showing that age-related female infertility was closely linked to mitochondrial dysfunction and aging mitochondria, and could be reversed through CoQ10 supplementation. Fertility clinics in Canada started to use CoQ10, and...

What is choline?   Choline is is an essential nutrient . It is a component of cell membranes and the neurotransmitter acetylcholine, which is essential for proper brain function, and it helps remove fat from the liver. The body naturally produces some choline and the rest can be obtained from the diet, but some people are not able to produce sufficient choline, particularly postmenopausal women and people with certain genetic traits, putting them at risk for choline deficiency. In addition, women need extra choline when pregnant or nursing. Although a small amount of choline is produced by your liver, the rest must be supplied through your diet. Unfortunately, an estimated 90 percent of the U.S. population are deficient in choline ( PMC 2009 ).   What does choline do?  Getting adequate choline from the diet helps prevent fatty liver (which can lead to reduced liver function) and muscle damage.  During pregnancy , choline taken by women may redu...

Abstract Methylene blue (MB), a phenothiazine-derived compound with a well-established history in medical applications, has recently garnered attention for its potential role in cancer therapy. This review examines the pharmacological properties, mechanisms of action, and emerging evidence supporting MB's anticancer effects. Through its redox-cycling capabilities, MB influences mitochondrial function, induces oxidative stress in malignant cells, and exhibits selective cytotoxicity. We further explore preclinical and clinical studies evaluating MB's efficacy and safety, while also discussing challenges and future research directions. Introduction Cancer remains a leading cause of morbidity and mortality worldwide, necessitating novel therapeutic approaches. Methylene blue, a heterocyclic aromatic dye initially introduced as an antimalarial agent, has demonstrated various pharmacological activities, including antimicrobial, neuroprotective, and antioxidant properties. Recently, ...

The Thomas Levy Chelation Protocol is a heavy metal detoxification approach developed by Dr. Thomas E. Levy, MD, JD, a cardiologist recognized for his expertise in oxidative stress and vitamin C therapy. This protocol combines high-dose vitamin C, glutathione, and other chelators to facilitate the removal of toxic metals such as mercury, lead, arsenic, and cadmium. Key Components of the Thomas Levy Protocol for Heavy Metal Detox 1. Vitamin C (Ascorbic Acid / Liposomal Vitamin C) Mechanism: Vitamin C acts as a mild chelator and a potent antioxidant, supporting the mobilization and excretion of metals while reducing oxidative stress ( 2 , 4 , 5 ). Studies have shown that vitamin C supplementation can significantly increase the urinary excretion of lead, supporting its role in heavy metal detoxification ( 4 ). Dosage: Oral: 3,000–10,000 mg/day (or to bowel tolerance). IV Vitamin C: 15–50g per session is often cited for more acute detox needs 2 . 2. Glutathione (Reduced Form – Best Taken L...